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List of works by Hsin-Chih Lai

A potential acyltransferase regulates swarming in Serratia marcescens

scientific article published on 28 April 2008

A simple gold nanoparticle probes assay for identification of Mycobacterium tuberculosis and Mycobacterium tuberculosis complex from clinical specimens.

scientific article

A swarming-defective mutant of Proteus mirabilis lacking a putative cation-transporting membrane P-type ATPase.

scientific article

Activation of NK cell cytotoxicity by the natural compound 2,3-butanediol

scientific article published on 16 July 2012

Activation of an NLRP3 inflammasome restricts Mycobacterium kansasii infection

scientific article (publication date: 2012)

Activation of multiple apoptotic pathways in human nasopharyngeal carcinoma cells by the prenylated isoflavone, osajin

scientific article

Alternative functions for the multifarious inflammasome.

scientific article published on June 2016

Amplified surface plasmon resonance immunosensor for interferon-gamma based on a streptavidin-incorporated aptamer.

scientific article

An iron detection system determines bacterial swarming initiation and biofilm formation.

scientific article

Anti-obesogenic and antidiabetic effects of plants and mushrooms.

scientific article

Antimicrobial resistance in Mycobacterium abscessus complex isolated from patients with skin and soft tissue infections at a tertiary teaching hospital in Taiwan.

scientific article

Antrodia cinnamomea produces anti-angiogenic effects by inhibiting the VEGFR2 signaling pathway.

scientific article published on 30 March 2018

Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice

scientific article published on 20 June 2017

Attenuation of lymphocyte immune responses during Mycobacterium avium complex-induced lung disease due to increasing expression of programmed death-1 on lymphocytes

scientific article published on 07 February 2017

Biochemical characterization of RssA-RssB, a two-component signal transduction system regulating swarming behavior in Serratia marcescens.

scientific article

Biosurfactant production by Serratia marcescens SS-1 and its isogenic strain SMdeltaR defective in SpnR, a quorum-sensing LuxR family protein.

scientific article published in May 2004

Characterization of the dapA-nlpB genetic locus involved in regulation of swarming motility, cell envelope architecture, hemolysin production, and cell attachment ability in Serratia marcescens

scientific article

Clinical manifestations, antibiotic susceptibility and molecular analysis of Mycobacterium kansasii isolates from a university hospital in Taiwan.

scientific article published on 7 July 2009

Clostridium innocuum is a vancomycin-resistant pathogen that may cause antibiotic-associated diarrhea

scientific article published on 16 February 2018

Co-ordinate expression of virulence genes during swarm-cell differentiation and population migration of Proteus mirabilis

scientific article published on 01 June 1992

Community-based multiple screening model

scientific article published on 01 April 2004

Corrigendum: Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota.

scientific article published on 11 July 2017

Corrigendum: The ATP-P2X7 Signaling Axis Is an Essential Sentinel for Intracellular Clostridium difficile Pathogen-Induced Inflammasome Activation

scientific article published on 17 July 2019

Cost-effectiveness analysis for determining optimal cut-off of immunochemical faecal occult blood test for population-based colorectal cancer screening (KCIS 16).

scientific article published in January 2007

Cost-effectiveness analysis of colorectal cancer screening with stool DNA testing in intermediate-incidence countries.

scientific article

Cross-talk between bacterial two-component systems drives stepwise regulation of flagellar biosynthesis in swarming development

scientific article published on 15 May 2017

Current dilemma and developments in the diagnosis of Mycobacterium tuberculosis Infection.

scientific article published in May 2008

Decreased T helper 17 cells in tuberculosis is associated with increased percentages of programmed death ligand 1, T helper 2 and regulatory T cells

scientific article

Development of an improved PCR-ICT hybrid assay for direct detection of Legionellae and Legionella pneumophila from cooling tower water specimens.

scientific article published on 19 May 2006

Diagnostic role of inflammatory and anti-inflammatory cytokines and effector molecules of cytotoxic T lymphocytes in tuberculous pleural effusion

scientific article published on 29 October 2014

Direct and simultaneous identification of Mycobacterium tuberculosis complex (MTBC) and Mycobacterium tuberculosis (MTB) by rapid multiplex nested PCR-ICT assay.

scientific article

Direct identification of mycobacteria from smear-positive sputum samples using an improved multiplex polymerase chain reaction assay.

scientific article published on 27 January 2012

Effects of obesity on depression: A role for inflammation and the gut microbiota.

scientific article

Ethanol extract of Phellinus merrillii protects against diethylnitrosamine- and 2-acetylaminofluorene-induced hepatocarcinogenesis in rats.

scientific article published on 2 August 2016

Fish tank granuloma caused by Mycobacterium marinum

scientific article

Fluoroquinolone resistance in Mycobacterium tuberculosis isolates: associated genetic mutations and relationship to antimicrobial exposure

scientific article published on 05 April 2007

Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota

scientific article published on 23 June 2015

Graphene oxide-based SPR biosensor chip for immunoassay applications

scientific article

Gut commensal Parabacteroides goldsteinii plays a predominant role in the anti-obesity effects of polysaccharides isolated from Hirsutella sinensis

scientific article published on 14 July 2018

High prevalence of antimicrobial resistance in rapidly growing mycobacteria in Taiwan.

scientific article

Hirsutella sinensis mycelium attenuates bleomycin-induced pulmonary inflammation and fibrosis in vivo

scientific article

Identification of CD24 as a cancer stem cell marker in human nasopharyngeal carcinoma

scientific article

Immunomodulatory Properties of Plants and Mushrooms.

scientific article published on 29 August 2017

Immunomodulatory properties of medicinal mushrooms: differential effects of water and ethanol extracts on NK cell-mediated cytotoxicity

scientific article published on 28 July 2016

Impact of the gut microbiota, prebiotics, and probiotics on human health and disease

scientific article

Interleukin 23/interleukin 17 axis activated by Mycobacterium avium complex (MAC) is attenuated in patients with MAC-lung disease.

scientific article

Is the inflammasome relevant for epithelial cell function?

scientific article

Isolation, Culture and Characterization of Hirsutella sinensis Mycelium from Caterpillar Fungus Fruiting Body

scientific article

Knockdown of c-MET induced apoptosis in ABCB1-overexpressed multidrug-resistance cancer cell lines.

scientific article published on 24 April 2015

ManA is regulated by RssAB signaling and promotes motility in Serratia marcescens.

scientific article published on 23 October 2013

Modulation of swarming and virulence by fatty acids through the RsbA protein in Proteus mirabilis.

scientific article published on December 2004

Molecular epidemiology of Clostridium difficile at a medical center in Taiwan: persistence of genetically clustering of A⁻B⁺ isolates and increase of A⁺B⁺ isolates.

scientific article

Mono- and poly-functional T cells in nontuberculous mycobacteria lung disease patients: Implications in analyzing risk of disease progression

scientific article published on 12 May 2019

Mushrooms - From cuisine to clinic

scientific article published on 01 November 2014

Myths and Realities Surrounding the Mysterious Caterpillar Fungus.

scientific article published in November 2017

N-acylhomoserine lactone-dependent cell-to-cell communication and social behavior in the genus Serratia.

scientific article

NK Cell-Derived IFN-γ Protects against Nontuberculous Mycobacterial Lung Infection

scientific article published on 30 July 2018

NK cells kill mycobacteria directly by releasing perforin and granulysin.

scientific article published on 19 August 2014

NLRP3 inflammasome is attenuated in patients with Mycobacterium avium complex lung disease and correlated with decreased interleukin-1β response and host susceptibility

scientific article published on 29 August 2019

Performance assessment of a nested-PCR assay (the RAPID BAP-MTB) and the BD ProbeTec ET system for detection of Mycobacterium tuberculosis in clinical specimens

scientific article published on October 2004

Performance assessment of the Capilia TB assay and the BD ProbeTec ET system for rapid culture confirmation of Mycobacterium tuberculosis.

scientific article published on 18 September 2007

Pinicolol B from Antrodia cinnamomea induces apoptosis of nasopharyngeal carcinoma cells.

scientific article published on 3 February 2017

Rapid identification of Mycobacterium avium clinical isolates by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

scientific article

Rapid identification of Mycobacterium tuberculosis infection by a new array format-based surface plasmon resonance method.

scientific article published on 8 March 2012

Regulation of swarming motility and flhDC(Sm) expression by RssAB signaling in Serratia marcescens.

scientific article published on 25 January 2008

Regulatory roles of spnT, a novel gene located within transposon TnTIR.

scientific article

Resveratrol ameliorates Serratia marcescens-induced acute pneumonia in rats.

scientific article published on 3 January 2008

Resveratrol induces apoptosis of human nasopharyngeal carcinoma cells via activation of multiple apoptotic pathways.

scientific article published on March 2011

Revealing the ultrastructure of the membrane pores of intact Serratia marcescens cells by atomic force microscopy

scientific article published on 15 October 2019

Role of RsmA in the regulation of swarming motility and virulence factor expression in Proteus mirabilis.

scientific article published in January 2003

RssAB signaling coordinates early development of surface multicellularity in Serratia marcescens.

scientific article

Subinhibitory Doses of Aminoglycoside Antibiotics Induce Changes in the Phenotype of Mycobacterium abscessus.

scientific article

The ATP-P2X7 Signaling Axis Is an Essential Sentinel for Intracellular Clostridium difficile Pathogen-Induced Inflammasome Activation

scientific article published on 16 March 2018

The RssB/RssA two-component system regulates biosynthesis of the tripyrrole antibiotic, prodigiosin, in Serratia marcescens.

scientific article published on 26 March 2010

The anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophages

scientific article (publication date: 2012)

The assessment of host and bacterial proteins in sputum from active pulmonary tuberculosis

scientific article published on 29 October 2016

The bacterial metabolite 2,3-butanediol ameliorates endotoxin-induced acute lung injury in rats.

scientific article published on 17 July 2007

The medicinal fungus Antrodia cinnamomea suppresses inflammation by inhibiting the NLRP3 inflammasome.

scientific article

Unraveling the role of the rssC gene of Serratia marcescens by atomic force microscopy

scientific article published on 20 October 2010

Use of fluorescein labelled antibody and fluorescence activated cell sorter for rapid identification of Mycobacterium species

scientific article published on 01 September 1998

Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/β-catenin pathway

scientific article

cis-Resveratrol produces anti-inflammatory effects by inhibiting canonical and non-canonical inflammasomes in macrophages

scientific article published on 22 October 2013

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