List of works - Kazuaki Yoshioka

ATP- and adenosine-mediated signaling in the central nervous system: purinergic receptor complex: generating adenine nucleotide-sensitive adenosine receptors.

scientific article published on February 2004

Agonist-promoted heteromeric oligomerization between adenosine A(1) and P2Y(1) receptors in living cells.

scientific article

Aldosterone inhibits endothelial morphogenesis and angiogenesis through the downregulation of vascular endothelial growth factor receptor-2 expression subsequent to peroxisome proliferator-activated receptor gamma ⬇️

scientific article published on December 28, 2011

Analysis of various types of single-polypeptide-chain (sc) heterodimeric A₂AR/D₂R complexes and their allosteric receptor-receptor interactions.

scientific article published on 2 December 2014

Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6.

scientific article published on 3 August 2017

Ca2+-independent, inhibitory effects of cyclic adenosine 5'-monophosphate on Ca2+ regulation of phosphoinositide 3-kinase C2alpha, Rho, and myosin phosphatase in vascular smooth muscle

scientific article published on 16 November 2006

Class II PI3Ks α and β Are Required for Rho-Dependent Uterine Smooth Muscle Contraction and Parturition in Mice

scientific article published on 01 January 2019

Class II phosphatidylinositol 3-kinase α and β isoforms are required for vascular smooth muscle Rho activation, contraction and blood pressure regulation in mice

scientific article published on 19 March 2020

Class II phosphoinositide 3-kinase alpha-isoform regulates Rho, myosin phosphatase and contraction in vascular smooth muscle

scientific article published on 01 March 2006

Early endothelialization associated with a biolimus A9 bioresorbable polymer stent in a porcine coronary model.

scientific article

Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function.

scientific article

Enhanced Ca2+-dependent activation of phosphoinositide 3-kinase class IIα isoform-Rho axis in blood vessels of spontaneously hypertensive rats.

scientific article published on 4 October 2010

Essential role for class II phosphoinositide 3-kinase alpha-isoform in Ca2+-induced, Rho- and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells.

scientific article published on 19 December 2006

Essential role of class II phosphatidylinositol-3-kinase-C2α in sphingosine 1-phosphate receptor-1-mediated signaling and migration in endothelial cells

scientific article published on 28 November 2012

Functions of heteromeric association between adenosine and P2Y receptors.

scientific article

G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.

scientific article published on 14 May 2008

Hetero-oligomerization of adenosine A1 receptors with P2Y1 receptors in rat brains

scientific journal article

Heteromeric association creates a P2Y-like adenosine receptor

scientific article published on 5 June 2001

In vivo microdialysis/liquid chromatography/tandem mass spectrometry for the on-line monitoring of melatonin in rat

scientific article published on 01 January 1999

Lysophosphatidic acid-induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4

scientific article published on 23 July 2019

MTMR4, a phosphoinositide-specific 3'-phosphatase, regulates TFEB activity and the endocytic and autophagic pathways

scientific article published on 02 July 2018

Negative regulation of endothelial morphogenesis and angiogenesis by S1P2 receptor

scientific article published on 02 June 2006

Nucleosides and nucleotides. 200. Reinvestigation of 5'-N-ethylcarboxamidoadenosine derivatives: structure-activity relationships for P(3) purinoceptor-like proteins.

scientific article

Oligomerization of adenosine A2A and dopamine D2 receptors in living cells

scientific article (publication date: 27 June 2003)

Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling

scientific article

Pharmacology of a unique adenosine binding site in rat brain using a selective ligand.

scientific article published in April 2001

Phosphatidylinositol 3-kinase class II α-isoform PI3K-C2α is required for transforming growth factor β-induced Smad signaling in endothelial cells

scientific article published on 22 January 2015

Purinergic-receptor oligomerization: implications for neural functions in the central nervous system.

scientific article

Rho-dependent, Rho kinase-independent inhibitory regulation of Rac and cell migration by LPA1 receptor in Gi-inactivated CHO cells.

scientific article published on 27 March 2006

S1P(2), the G protein-coupled receptor for sphingosine-1-phosphate, negatively regulates tumor angiogenesis and tumor growth in vivo in mice.

scientific article published on 12 January 2010

Sphigosine-1-phosphate receptor 1 promotes neointimal hyperplasia in a mouse model of carotid artery injury

scientific article published on 15 February 2019

Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases.

scientific article published on 23 June 2012

Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice.

scientific article

Sphingosine-1-phosphate receptor-2 facilitates pulmonary fibrosis through potentiating IL-13 pathway in macrophages.

scientific article published on 21 May 2018

Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system.

scientific article published on 22 April 2008

Sphingosine-1-phosphate signaling in physiology and diseases.

scientific article published on 07 June 2012

Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice.

scientific article published on 3 March 2010

TGFβ receptor endocytosis and Smad signaling require synaptojanin1, PI3K-C2α-, and INPP4B-mediated phosphoinositide conversions

scientific article published on 08 January 2020

The class II phosphoinositide 3-kinases PI3K-C2α and PI3K-C2β differentially regulate clathrin-dependent pinocytosis in human vascular endothelial cells

scientific article published on 29 October 2018

List of works by Kazuaki Yoshioka

ATP- and adenosine-mediated signaling in the central nervous system: purinergic receptor complex: generating adenine nucleotide-sensitive adenosine receptors.

Agonist-promoted heteromeric oligomerization between adenosine A(1) and P2Y(1) receptors in living cells.

Aldosterone inhibits endothelial morphogenesis and angiogenesis through the downregulation of vascular endothelial growth factor receptor-2 expression subsequent to peroxisome proliferator-activated receptor gamma ⬇️

Analysis of various types of single-polypeptide-chain (sc) heterodimeric A₂AR/D₂R complexes and their allosteric receptor-receptor interactions.

Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6.

Ca2+-independent, inhibitory effects of cyclic adenosine 5'-monophosphate on Ca2+ regulation of phosphoinositide 3-kinase C2alpha, Rho, and myosin phosphatase in vascular smooth muscle

Class II PI3Ks α and β Are Required for Rho-Dependent Uterine Smooth Muscle Contraction and Parturition in Mice

Class II phosphatidylinositol 3-kinase α and β isoforms are required for vascular smooth muscle Rho activation, contraction and blood pressure regulation in mice

Class II phosphoinositide 3-kinase alpha-isoform regulates Rho, myosin phosphatase and contraction in vascular smooth muscle

Early endothelialization associated with a biolimus A9 bioresorbable polymer stent in a porcine coronary model.

Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function.

Enhanced Ca2+-dependent activation of phosphoinositide 3-kinase class IIα isoform-Rho axis in blood vessels of spontaneously hypertensive rats.

Essential role for class II phosphoinositide 3-kinase alpha-isoform in Ca2+-induced, Rho- and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells.

Essential role of class II phosphatidylinositol-3-kinase-C2α in sphingosine 1-phosphate receptor-1-mediated signaling and migration in endothelial cells

Functions of heteromeric association between adenosine and P2Y receptors.

G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.

Hetero-oligomerization of adenosine A1 receptors with P2Y1 receptors in rat brains

Heteromeric association creates a P2Y-like adenosine receptor

In vivo microdialysis/liquid chromatography/tandem mass spectrometry for the on-line monitoring of melatonin in rat

Lysophosphatidic acid-induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4

MTMR4, a phosphoinositide-specific 3'-phosphatase, regulates TFEB activity and the endocytic and autophagic pathways

Negative regulation of endothelial morphogenesis and angiogenesis by S1P2 receptor

Nucleosides and nucleotides. 200. Reinvestigation of 5'-N-ethylcarboxamidoadenosine derivatives: structure-activity relationships for P(3) purinoceptor-like proteins.

Oligomerization of adenosine A2A and dopamine D2 receptors in living cells

Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling

Pharmacology of a unique adenosine binding site in rat brain using a selective ligand.

Phosphatidylinositol 3-kinase class II α-isoform PI3K-C2α is required for transforming growth factor β-induced Smad signaling in endothelial cells

Purinergic-receptor oligomerization: implications for neural functions in the central nervous system.

Rho-dependent, Rho kinase-independent inhibitory regulation of Rac and cell migration by LPA1 receptor in Gi-inactivated CHO cells.

S1P(2), the G protein-coupled receptor for sphingosine-1-phosphate, negatively regulates tumor angiogenesis and tumor growth in vivo in mice.

Sphigosine-1-phosphate receptor 1 promotes neointimal hyperplasia in a mouse model of carotid artery injury

Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases.

Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice.

Sphingosine-1-phosphate receptor-2 facilitates pulmonary fibrosis through potentiating IL-13 pathway in macrophages.

Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system.

Sphingosine-1-phosphate signaling in physiology and diseases.

Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice.

TGFβ receptor endocytosis and Smad signaling require synaptojanin1, PI3K-C2α-, and INPP4B-mediated phosphoinositide conversions

The class II phosphoinositide 3-kinases PI3K-C2α and PI3K-C2β differentially regulate clathrin-dependent pinocytosis in human vascular endothelial cells