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List of works by M. Alejandra Tortorici

A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of Human Respiratory Syncytial Virus

scientific article

A base-specific recognition signal in the 5' consensus sequence of rotavirus plus-strand RNAs promotes replication of the double-stranded RNA genome segments

scientific article

A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion.

scientific article published in November 2017

A positive-strand RNA virus uses alternative protein-protein interactions within a viral protease/cofactor complex to switch between RNA replication and virion morphogenesis

scientific article

Arenavirus nucleocapsid protein displays a transcriptional antitermination activity in vivo.

scientific article

Broad betacoronavirus neutralization by a stem helix–specific human antibody

scientific article

Coupling of rotavirus genome replication and capsid assembly.

scientific article published on January 2007

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

scientific article published on 18 May 2020

Crucial steps in the structure determination of a coronavirus spike glycoprotein using cryo-electron microscopy

scientific article

Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

scientific article

Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding

scientific article published on 17 June 2020

Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding

scientific article published on 11 August 2020

Expression and purification of Z protein from Junín virus

scientific article

Functional and evolutionary insight from the crystal structure of rubella virus protein E1

scientific article

Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy

scientific article

Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections.

scientific article published in November 2017

Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein.

scientific article published on 18 September 2017

Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology

scientific article published on 16 September 2020

Mechanism for Coordinated RNA Packaging and Genome Replication by Rotavirus Polymerase VP1

scientific article

Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc.

scientific article

Protocol and Reagents for Pseudotyping Lentiviral Particles with SARS-CoV-2 Spike Protein for Neutralization Assays

scientific article published on 06 May 2020

Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 Spike protein for neutralization assays

scientific article published on 24 April 2020

Rotavirus NSP2 interferes with the core lattice protein VP2 in initiation of minus-strand synthesis.

scientific article published in August 2003

Rotavirus genome replication and morphogenesis: role of the viroplasm.

scientific article published on January 2006

Rotavirus glycoprotein NSP4 is a modulator of viral transcription in the infected cell.

scientific article

SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern

scientific article

Structural Studies of Coronavirus Fusion Proteins

Structural and functional analysis of a potent sarbecovirus neutralizing antibody

scientific article published on 09 April 2020

Structural basis for human coronavirus attachment to sialic acid receptors

scientific article published in June 2019

Structural insights into coronavirus entry

scientific article published on 22 August 2019

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

scientific article published on 06 March 2020

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

scientific article published on 01 December 2020

Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors

scientific article published on 02 December 2019

Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion.

scientific article published on 3 October 2017

Template recognition and formation of initiation complexes by the replicase of a segmented double-stranded RNA virus.

scientific article published on 3 June 2003

The Ancient Gamete Fusogen HAP2 Is a Eukaryotic Class II Fusion Protein

scientific article published on February 2017

Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

scientific article

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

scientific article published on 21 February 2019

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

scientific article published on 01 December 2020

X-ray structure of the pestivirus NS3 helicase and its conformation in solution.

scientific article