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List of works by Paola Monti

3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro.

scientific article

5-Methylcytosine at HpaII sites in p53 is not hypermutable after UVC irradiation

scientific article published in December 1999

Autophagy induced by SAHA affects mutant P53 degradation and cancer cell survival

scientific article published on 19 February 2019

Characterization of the p53 mutants ability to inhibit p73β transactivation using a yeast-based functional assay

scientific article published on 01 August 2003

Comparison of ibrutinib and idelalisib plus rituximab in real-life relapsed/resistant chronic lymphocytic leukemia cases

scientific article published on 30 December 2020

Comparison of the biological effects of MMS and Me-lex, a minor groove methylating agent: clarifying the role of N3-methyladenine.

scientific article

Determining mutational fingerprints at the human p53 locus with a yeast functional assay: a new tool for molecular epidemiology

scientific article published on 01 March 1997

Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.

scientific article

Etoposide-resistance in a neuroblastoma model cell line is associated with 13q14.3 mono-allelic deletion and miRNA-15a/16-1 down-regulation

scientific article published in Scientific Reports

Gambogic acid counteracts mutant p53 stability by inducing autophagy.

scientific article published on 26 November 2016

Heterogeneousp53 mutations in a Burkitt lymphoma from an AIDS patient with monoclonalc-myc andVDJ rearrangements ⬇️

scientific article published on December 10, 1997

High frequency of genomic deletions induced by Me-lex, a sequence selective N3-adenine methylating agent, at the Hprt locus in Chinese hamster ovary cells.

scientific article published on September 2009

Human transcription factors in yeast: the fruitful examples of P53 and NF-кB.

scientific article

Identification of a novel TP53 germline mutation in a large Italian Li-Fraumeni syndrome Family

scientific article published on 01 February 2009

Influences of base excision repair defects on the lethality and mutagenicity induced by Me-lex, a sequence-selective N3-adenine methylating agent.

scientific article published on 31 May 2002

Mutagenicity of N3-methyladenine: a multi-translesion polymerase affair.

scientific article published on January 2010

NEAT1 Long Isoform Is Highly Expressed in Chronic Lymphocytic Leukemia Irrespectively of Cytogenetic Groups or Clinical Outcome

scientific article published on 13 March 2020

P53 family members modulate the expression of PRODH, but not PRODH2, via intronic p53 response elements.

scientific article

P63 modulates the expression of the WDFY2 gene which is implicated in cancer regulation and limb development

scientific article published on 01 December 2019

Relationship between DNA methylation and mutational patterns induced by a sequence selective minor groove methylating agent

scientific article published on 01 June 1999

Rev1 and Polzeta influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent.

scientific article published on 7 January 2008

SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations

scientific article published on 16 September 2019

Simple identification of dominant p53 mutants by a yeast functional assay

scientific article published on 01 October 1997

Structure of p73 DNA-binding domain tetramer modulates p73 transactivation

scientific article

Studying p53 family proteins in yeast: induction of autophagic cell death and modulation by interactors and small molecules.

scientific article published on 28 September 2014

TP53 dysfunction in chronic lymphocytic leukemia: clinical relevance in the era of B-cell receptors and BCL-2 inhibitors

scientific article published on 17 June 2020

TP53 mutants in the tower of babel of cancer progression

scientific article published on 14 March 2014

TP63 mutations are frequent in cutaneous melanoma, support UV etiology, but their role in melanomagenesis is unclear.

scientific article published on 14 August 2017

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis.

scientific article published on 17 November 2012

Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code

scientific article

Transcriptional functionality of germ line p53 mutants influences cancer phenotype.

scientific article

Ultraviolet-light induced p53 mutational spectrum in yeast is indistinguishable from p53 mutations in human skin cancer ⬇️

scientific article published on May 1, 1998

Yeast As a Chassis for Developing Functional Assays to Study Human P53

scientific article published on 04 August 2019

p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements

scientific article published in June 2001

p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening system

scientific article

∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites

scientific article

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