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List of works by Keisuke Okita

A more efficient method to generate integration-free human iPS cells

scientific article (publication date: May 2011)

Adoptive Transfer of CD8+ T Cells Generated from Induced Pluripotent Stem Cells Triggers Regressions of Large Tumors Along with Immunological Memory

scientific article published on 12 April 2016

An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells

scientific article

Artificial acceleration of mammalian cell reprogramming by bacterial proteins

scientific article

Cardiomyocytes Derived from MHC-Homozygous Induced Pluripotent Stem Cells Exhibit Reduced Allogeneic Immunogenicity in MHC-Matched Non-human Primates

scientific article published on 04 February 2016

Characterization of dendritic cells and macrophages generated by directed differentiation from mouse induced pluripotent stem cells

scientific article published on May 2009

Clonal variation of human induced pluripotent stem cells for induction into the germ cell fate.

scientific article published on 27 April 2017

De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency

scientific article published on 02 May 2019

Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells

scientific article

Direct comparison of autologous and allogeneic transplantation of iPSC-derived neural cells in the brain of a non-human primate

scientific article

Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells

scientific article

Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells

scientific article

Drug screening for ALS using patient-specific induced pluripotent stem cells

scientific article published on August 2012

ECAT11/L1td1 is enriched in ESCs and rapidly activated during iPSC generation, but it is dispensable for the maintenance and induction of pluripotency

scientific article published in 2011

Endomucin is expressed in embryonic dorsal aorta and is able to inhibit cell adhesion.

scientific article

Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects.

scientific article published on 22 May 2015

Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity

scientific article published on 26 July 2016

Establishment of Human Neural Progenitor Cells from Human Induced Pluripotent Stem Cells with Diverse Tissue Origins

scientific article published on 26 April 2016

Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells

scientific article

Generation and characterization of induced pluripotent stem cells from Aid-deficient mice

scientific article

Generation of germline-competent induced pluripotent stem cells

scientific article (publication date: 19 July 2007)

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

scientific article (publication date: 2008)

Generation of mouse-induced pluripotent stem cells with plasmid vectors

scientific article

Generation of pluripotent stem cells from adult mouse liver and stomach cells

scientific article

Generation of retinal cells from mouse and human induced pluripotent stem cells

scientific article

Genome-wide DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) residing in mouse pluripotent stem cells.

scientific article published on 13 May 2010

Genomic organization and characterization of the mouse ELYS gene

scientific article published on 01 May 2003

Gingival Fibroblasts as Autologous Feeders for Induced Pluripotent Stem Cells

scientific article published on 14 October 2015

Gingival fibroblasts as a promising source of induced pluripotent stem cells

scientific article

Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors

scientific article published on 17 February 2018

Human and mouse induced pluripotent stem cells are differentially reprogrammed in response to kinase inhibitors.

scientific article

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model.

scientific article published in August 2017

Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency.

scientific article published in May 2017

Hypoxia enhances the generation of induced pluripotent stem cells

scientific article published on 27 August 2009

Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues

scientific journal article

Idiopathic Parkinson's disease patient-derived induced pluripotent stem cells function as midbrain dopaminergic neurons in rodent brains.

scientific article

Immunogenicity of induced pluripotent stem cells

scientific article published on 01 September 2011

Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development

scientific article published on 01 January 2019

Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice

scientific article

Induced pluripotent stem cells: opportunities and challenges

scientific article

Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A

scientific article

Induction of pluripotency by defined factors

scientific article published on 24 April 2010

Induction of pluripotent stem cells from fibroblast cultures

scientific article

Intracellular signaling pathways regulating pluripotency of embryonic stem cells

scientific journal article

KLF4 N-terminal variance modulates induced reprogramming to pluripotency

scientific article

Low Cell-Matrix Adhesion Reveals Two Subtypes of Human Pluripotent Stem Cells

scientific article published on 28 June 2018

MHC matching improves engraftment of iPSC-derived neurons in non-human primates

scientific article published on 30 August 2017

Methods for iPS cell generation for basic research and clinical applications.

scientific article

Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness

scientific article published on 21 February 2013

Modelling urea-cycle disorder citrullinemia type 1 with disease-specific iPSCs.

scientific article published on 13 March 2017

OVOL2 Maintains the Transcriptional Program of Human Corneal Epithelium by Suppressing Epithelial-to-Mesenchymal Transition.

scientific article

Orderly hematopoietic development of induced pluripotent stem cells via Flk-1(+) hemoangiogenic progenitors

scientific article

Pluripotent stem cell model of Shwachman-Diamond syndrome reveals apoptotic predisposition of hemoangiogenic progenitors

scientific article published on 09 September 2020

Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation

scientific article

Regulation of hematopoietic development in the aorta-gonad-mesonephros region mediated by Lnk adaptor protein

scientific journal article

Reprogramming of Melanoma Tumor-Infiltrating Lymphocytes to Induced Pluripotent Stem Cells

scientific article published on 28 December 2015

Response to comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".

scientific article published in June 2013

Rewinding the process of mammalian extinction

scientific article

Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts

scientific article published on 19 May 2009

Screening of Human cDNA Library Reveals Two differentiation-Related Genes, HHEX and HLX, as Promoters of Early Phase Reprogramming toward Pluripotency

scientific article

Spred-2 suppresses aorta-gonad-mesonephros hematopoiesis by inhibiting MAP kinase activation

scientific article

Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs.

scientific article published on 11 April 2018

Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

scientific article (publication date: 27 August 2009)

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility

scientific article published on 07 March 2019

Transcriptional Analysis of Intravenous Immunoglobulin Resistance in Kawasaki Disease Using an Induced Pluripotent Stem Cell Disease Model

scientific article published on 19 November 2016

Transplantation of mouse induced pluripotent stem cells into the cochlea

scientific article

Variation in the safety of induced pluripotent stem cell lines

scientific article

X-linked severe combined immunodeficiency (X-SCID) rats for xeno-transplantation and behavioral evaluation.

scientific article published on 4 February 2015

iPS cells for transplantation.

scientific article published on February 2011

miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues

scientific article published on July 2010

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