List of works - Richard A Hubner

"If You Prick Us, Do We Not Bleed?" Whom Should We Choose?

scientific article published on 04 January 2016

18F-FLT PET imaging of cellular proliferation in pancreatic cancer.

scientific article

18F-fluorodeoxyglucose positron emission tomography (18FDG-PET) for patients with biliary tract cancer: Systematic review and meta-analysis

scientific article published on 21 February 2019

A Phase II Study of BEZ235 in Patients with Everolimus-resistant, Advanced Pancreatic Neuroendocrine Tumours

scientific article published on February 2016

A multicentre comparison between Child Pugh and Albumin-Bilirubin scores in patients treated with sorafenib for Hepatocellular Carcinoma.

scientific article

A phase II study of antibody-drug conjugate, TAK-264 (MLN0264) in previously treated patients with advanced or metastatic pancreatic adenocarcinoma expressing guanylyl cyclase C.

scientific article published on 19 May 2017

Adjuvant chemotherapy and outcomes in patients with nodal and resection margin-negative pancreatic ductal adenocarcinoma: A systematic review and meta-analysis

scientific article published on 05 March 2019

Analysis of circulating cell-free DNA identifies KRAS copy number gain and mutation as a novel prognostic marker in Pancreatic cancer

scientific article published on 12 August 2019

Appendiceal Goblet Cell Carcinoids: Management Considerations from a Reference Peritoneal Tumour Service Centre and ENETS Centre of Excellence.

scientific article published on 10 September 2015

Chemotherapy for advanced non-pancreatic well-differentiated neuroendocrine tumours of the gastrointestinal tract, a systematic review and meta-analysis: A lost cause?

scientific article published on 25 January 2016

Combination chemotherapy with carboplatin, capecitabine and epirubicin (ECarboX) as second- or third-line treatment in patients with relapsed ovarian cancer: a phase I/II trial.

scientific article published on January 2006

Design and Validation of the GI-NEC Score to Prognosticate Overall Survival in Patients With High-Grade Gastrointestinal Neuroendocrine Carcinomas.

scientific article published on 27 January 2017

Differential tissue and enzyme inhibitory effects of the vasopeptidase inhibitor omapatrilat in the rat.

scientific article published in September 2003

Elderly patients diagnosed with hepatopancreatobiliary malignancies: A challenge beyond resection

scientific article published on 06 January 2017

Evidence for cardioprotective, renoprotective, and vasculoprotective effects of vasopeptidase inhibitors in disease ⬇️

scientific article published on December 1, 2001

Excision Repair Cross-Complementation Group 1 (ERCC1) Status and Lung Cancer Outcomes: A Meta-Analysis of Published Studies and Recommendations ⬇️

scientific article published on October 14, 2011

Folate Metabolism Polymorphisms Influence Risk of Colorectal Adenoma Recurrence

scientific article published on 01 September 2006

Folate and colorectal cancer prevention.

scientific article published on 16 December 2008

Gefitinib for oesophageal cancer progressing after chemotherapy (COG): a phase 3, multicentre, double-blind, placebo-controlled randomised trial.

scientific article published on 17 June 2014

Gemcitabine plus capecitabine in unselected patients with advanced pancreatic cancer.

scientific article

HER2/HER3 pathway in biliary tract malignancies; systematic review and meta-analysis: a potential therapeutic target?

scientific article published on 15 December 2016

Identification of clinical biomarkers for patients with advanced hepatocellular carcinoma receiving sorafenib.

scientific article published on 19 August 2016

Impact of biliary stent-related events in patients diagnosed with advanced pancreatobiliary tumours receiving palliative chemotherapy.

scientific article published on July 2016

Influence of co-morbidity on renal function assessment by Cockcroft-Gault calculation in lung cancer and mesothelioma patients receiving platinum-based chemotherapy.

scientific article published on 21 February 2011

MTHFR C677T and colorectal cancer risk: A meta-analysis of 25 populations

article

Molecular Profiling in Daily Clinical Practice: Practicalities in Advanced Cholangiocarcinoma and Other Biliary Tract Cancers

scientific article published on 03 September 2020

Nanoliposomal Irinotecan in the Clinical Practice Guideline for Metastatic Pancreatic Cancer: Applicability to Clinical Situations.

scientific article

Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial

scientific article published on 20 November 2015

Phase II study of the antibody-drug conjugate TAK-264 (MLN0264) in patients with metastatic or recurrent adenocarcinoma of the stomach or gastroesophageal junction expressing guanylyl cyclase C.

scientific article published on 11 February 2017

Practical management of sunitinib toxicities in the treatment of pancreatic neuroendocrine tumors.

scientific article published on 16 September 2014

Prognostic factors for disease relapse in patients with neuroendocrine tumours who underwent curative surgery

scientific article published on 26 May 2016

Quality-adjusted survival with combination nal-IRI+5-FU/LV vs 5-FU/LV alone in metastatic pancreatic cancer patients previously treated with gemcitabine-based therapy: a Q-TWiST analysis

scientific article published on 28 March 2017

Reply to the letter to the editor 'second-line chemotherapy in advanced biliary cancer: the present now will later be past' by Vivaldi et al

scientific article published on 19 August 2014

Routine measurement of plasma chromogranin B has limited clinical utility in the management of patients with neuroendocrine tumours

scientific article

Second-line chemotherapy in advanced biliary cancer: a systematic review

scientific article published on 25 April 2014

Second-line treatment in patients with advanced extra-pulmonary poorly differentiated neuroendocrine carcinoma: a systematic review and meta-analysis

scientific article published on 27 April 2020

Somatostatin receptor expression in hepatocellular carcinoma: prognostic and therapeutic considerations.

scientific article

Sorafenib as first-line therapy in patients with advanced Child-Pugh B hepatocellular carcinoma-a meta-analysis

scientific article published on 29 October 2018

Sorafenib for the Treatment of Advanced Hepatocellular Cancer - a UK Audit

scientific article published on 10 December 2016

Sorafenib in combination with transarterial chemoembolisation in patients with unresectable hepatocellular carcinoma (TACE 2): a randomised placebo-controlled, double-blind, phase 3 trial.

scientific article published on 22 June 2017

Sunitinib for advanced pancreatic neuroendocrine tumors.

scientific article published on December 2011

Systematic review of microsatellite instability and colorectal cancer prognosis

scientific article

Targeting the Epidermal Growth Factor Receptor in Addition to Chemotherapy in Patients with Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis

scientific article

Telotristat ethyl: a new option for the management of carcinoid syndrome.

scientific article published on 7 November 2016

Temozolomide-Capecitabine Chemotherapy for Neuroendocrine Neoplasms: The Dilemma of Treatment Duration

scientific article published on 17 September 2019

The HER3 pathway as a potential target for inhibition in patients with biliary tract cancers

scientific article published in PLoS ONE

The dark side of T1 non-appendiceal small bowel neuroendocrine tumors

scientific article published on 09 May 2017

Thymidylate synthase polymorphisms, folate and B-vitamin intake, and risk of colorectal adenoma.

scientific article published on 30 October 2007

To BRCA or Not to PALB

scientific article published on 29 June 2015

Update on Treatment Options for Advanced Bile Duct Tumours: Radioembolisation for Advanced Cholangiocarcinoma

scientific article

Urgent need for consensus: international survey of clinical practice exploring use of platinum-etoposide chemotherapy for advanced extra-pulmonary high grade neuroendocrine carcinoma (EP-G3-NEC)

scientific article published on 30 November 2018

List of works by Richard A Hubner

"If You Prick Us, Do We Not Bleed?" Whom Should We Choose?

18F-FLT PET imaging of cellular proliferation in pancreatic cancer.

18F-fluorodeoxyglucose positron emission tomography (18FDG-PET) for patients with biliary tract cancer: Systematic review and meta-analysis

A Phase II Study of BEZ235 in Patients with Everolimus-resistant, Advanced Pancreatic Neuroendocrine Tumours

A multicentre comparison between Child Pugh and Albumin-Bilirubin scores in patients treated with sorafenib for Hepatocellular Carcinoma.

A phase II study of antibody-drug conjugate, TAK-264 (MLN0264) in previously treated patients with advanced or metastatic pancreatic adenocarcinoma expressing guanylyl cyclase C.

Adjuvant chemotherapy and outcomes in patients with nodal and resection margin-negative pancreatic ductal adenocarcinoma: A systematic review and meta-analysis

Analysis of circulating cell-free DNA identifies KRAS copy number gain and mutation as a novel prognostic marker in Pancreatic cancer

Appendiceal Goblet Cell Carcinoids: Management Considerations from a Reference Peritoneal Tumour Service Centre and ENETS Centre of Excellence.

Chemotherapy for advanced non-pancreatic well-differentiated neuroendocrine tumours of the gastrointestinal tract, a systematic review and meta-analysis: A lost cause?

Combination chemotherapy with carboplatin, capecitabine and epirubicin (ECarboX) as second- or third-line treatment in patients with relapsed ovarian cancer: a phase I/II trial.

Design and Validation of the GI-NEC Score to Prognosticate Overall Survival in Patients With High-Grade Gastrointestinal Neuroendocrine Carcinomas.

Differential tissue and enzyme inhibitory effects of the vasopeptidase inhibitor omapatrilat in the rat.

Elderly patients diagnosed with hepatopancreatobiliary malignancies: A challenge beyond resection

Evidence for cardioprotective, renoprotective, and vasculoprotective effects of vasopeptidase inhibitors in disease ⬇️

Excision Repair Cross-Complementation Group 1 (ERCC1) Status and Lung Cancer Outcomes: A Meta-Analysis of Published Studies and Recommendations ⬇️

Folate Metabolism Polymorphisms Influence Risk of Colorectal Adenoma Recurrence

Folate and colorectal cancer prevention.

Gefitinib for oesophageal cancer progressing after chemotherapy (COG): a phase 3, multicentre, double-blind, placebo-controlled randomised trial.

Gemcitabine plus capecitabine in unselected patients with advanced pancreatic cancer.

HER2/HER3 pathway in biliary tract malignancies; systematic review and meta-analysis: a potential therapeutic target?

Identification of clinical biomarkers for patients with advanced hepatocellular carcinoma receiving sorafenib.

Impact of biliary stent-related events in patients diagnosed with advanced pancreatobiliary tumours receiving palliative chemotherapy.

Influence of co-morbidity on renal function assessment by Cockcroft-Gault calculation in lung cancer and mesothelioma patients receiving platinum-based chemotherapy.

MTHFR C677T and colorectal cancer risk: A meta-analysis of 25 populations

Molecular Profiling in Daily Clinical Practice: Practicalities in Advanced Cholangiocarcinoma and Other Biliary Tract Cancers

Nanoliposomal Irinotecan in the Clinical Practice Guideline for Metastatic Pancreatic Cancer: Applicability to Clinical Situations.

Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial

Phase II study of the antibody-drug conjugate TAK-264 (MLN0264) in patients with metastatic or recurrent adenocarcinoma of the stomach or gastroesophageal junction expressing guanylyl cyclase C.

Practical management of sunitinib toxicities in the treatment of pancreatic neuroendocrine tumors.

Prognostic factors for disease relapse in patients with neuroendocrine tumours who underwent curative surgery

Quality-adjusted survival with combination nal-IRI+5-FU/LV vs 5-FU/LV alone in metastatic pancreatic cancer patients previously treated with gemcitabine-based therapy: a Q-TWiST analysis

Reply to the letter to the editor 'second-line chemotherapy in advanced biliary cancer: the present now will later be past' by Vivaldi et al

Routine measurement of plasma chromogranin B has limited clinical utility in the management of patients with neuroendocrine tumours

Second-line chemotherapy in advanced biliary cancer: a systematic review

Second-line treatment in patients with advanced extra-pulmonary poorly differentiated neuroendocrine carcinoma: a systematic review and meta-analysis

Somatostatin receptor expression in hepatocellular carcinoma: prognostic and therapeutic considerations.

Sorafenib as first-line therapy in patients with advanced Child-Pugh B hepatocellular carcinoma-a meta-analysis

Sorafenib for the Treatment of Advanced Hepatocellular Cancer - a UK Audit

Sorafenib in combination with transarterial chemoembolisation in patients with unresectable hepatocellular carcinoma (TACE 2): a randomised placebo-controlled, double-blind, phase 3 trial.

Sunitinib for advanced pancreatic neuroendocrine tumors.

Systematic review of microsatellite instability and colorectal cancer prognosis

Targeting the Epidermal Growth Factor Receptor in Addition to Chemotherapy in Patients with Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis

Telotristat ethyl: a new option for the management of carcinoid syndrome.

Temozolomide-Capecitabine Chemotherapy for Neuroendocrine Neoplasms: The Dilemma of Treatment Duration

The HER3 pathway as a potential target for inhibition in patients with biliary tract cancers

The dark side of T1 non-appendiceal small bowel neuroendocrine tumors

Thymidylate synthase polymorphisms, folate and B-vitamin intake, and risk of colorectal adenoma.

To BRCA or Not to PALB

Update on Treatment Options for Advanced Bile Duct Tumours: Radioembolisation for Advanced Cholangiocarcinoma

Urgent need for consensus: international survey of clinical practice exploring use of platinum-etoposide chemotherapy for advanced extra-pulmonary high grade neuroendocrine carcinoma (EP-G3-NEC)