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List of works by Olga Abian

A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin

scientific article published on 11 September 2020

A look at ligand binding thermodynamics in drug discovery

scientific article published on March 2017

A unified framework based on the binding polynomial for characterizing biological systems by isothermal titration calorimetry.

scientific article

Allosteric inhibitors of the NS3 protease from the hepatitis C virus

scientific article (publication date: 2013)

Altering the interfacial activation mechanism of a lipase by solid-phase selective chemical modification

scientific article published on 23 August 2012

Amphipathic helical peptides hamper protein-protein interactions of the intrinsically disordered chromatin nuclear protein 1 (NUPR1)

scientific article published on 10 March 2018

Biophysical Screening for Identifying Pharmacological Chaperones and Inhibitors Against Conformational and Infectious Diseases

scientific article published on 31 January 2016

Biosourced All-Acrylic ABA Block Copolymers with Lactic Acid-Based Soft Phase

scientific article published on 05 December 2020

Co-aggregation of penicillin g acylase and polyionic polymers: an easy methodology to prepare enzyme biocatalysts stable in organic media.

scientific article

Correction to: Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study

scientific article published in 2021

Cysteine Mutational Studies Provide Insight into a Thiol-Based Redox Switch Mechanism of Metal and DNA Binding in FurA from Anabaena sp. PCC 7120.

scientific article published on 28 September 2015

Deconvolution analysis for classifying gastric adenocarcinoma patients based on differential scanning calorimetry serum thermograms.

scientific article published on 23 January 2015

Design and structure of an equilibrium protein folding intermediate: a hint into dynamical regions of proteins

scientific article

Designing and repurposing drugs to target intrinsically disordered proteins for cancer treatment: using NUPR1 as a paradigm

scientific article published on 16 May 2019

Determination of protein-protein interactions through aldehyde-dextran intermolecular cross-linking

scientific article published on 01 September 2004

Enantioselective synthesis of phenylacetamides in the presence of high organic cosolvent concentrations catalyzed by stabilized penicillin G acylase. Effect of the acyl donor.

scientific article

Enzyme structure and function protection from gastrointestinal degradation using enteric coatings

scientific article published on 23 July 2018

Epoxy sepabeads: a novel epoxy support for stabilization of industrial enzymes via very intense multipoint covalent attachment.

scientific article published in May 2002

Epoxy-amino groups: a new tool for improved immobilization of proteins by the epoxy method.

scientific article published in May 2003

Experimental validation of in silico target predictions on synergistic protein targets.

scientific article

Improving the industrial production of 6-APA: enzymatic hydrolysis of penicillin G in the presence of organic solvents.

scientific article

Increase in conformational stability of enzymes immobilized on epoxy-activated supports by favoring additional multipoint covalent attachment*

scientific article published on 01 April 2000

Janus Dendrimers to Assess the Anti-HCV Activity of Molecules in Cell-Assays

scientific article published on 07 November 2020

Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis

scientific article published on 28 March 2019

Mechanism of FMN Binding to the Apoflavodoxin from Helicobacter pylori

scientific article published on 15 September 2011

Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors

scientific article published on 04 September 2019

Molecular Context-Dependent Effects Induced by Rett Syndrome-Associated Mutations in MeCP2

scientific article published on 10 November 2020

Multifunctional epoxy supports: a new tool to improve the covalent immobilization of proteins. The promotion of physical adsorptions of proteins on the supports before their covalent linkage

scientific article published on 01 January 2000

NS3 protease from hepatitis C virus: biophysical studies on an intrinsically disordered protein domain

scientific article

New cationic exchanger support for reversible immobilization of proteins.

scientific article published in January 2004

Novel bifunctional epoxy/thiol-reactive support to immobilize thiol containing proteins by the epoxy chemistry.

scientific article

On the link between conformational changes, ligand binding and heat capacity

scientific article published on 14 October 2015

Protein-cation interactions: structural and thermodynamic aspects.

scientific article published on June 2011

Rationally designed interfacial peptides are efficient in vitro inhibitors of HIV-1 capsid assembly with antiviral activity

scientific article

Rescuing compound bioactivity in a secondary cell-based screening by using γ-cyclodextrin as a molecular carrier.

scientific article

Reversible and strong immobilization of proteins by ionic exchange on supports coated with sulfate-dextran.

scientific article

Reversible enzyme immobilization via a very strong and nondistorting ionic adsorption on support-polyethylenimine composites

scientific article published on 01 April 2000

Semisynthetic peptide-lipase conjugates for improved biotransformations

scientific article published on 02 August 2012

Shell Cross-Linked Polymeric Micelles as Camptothecin Nanocarriers for Anti-HCV Therapy.

scientific article published on 5 June 2015

Stabilization of enzymes by multipoint immobilization of thiolated proteins on new epoxy-thiol supports.

scientific article published in June 2005

Stabilization of penicillin G acylase from Escherichia coli: site-directed mutagenesis of the protein surface to increase multipoint covalent attachment.

scientific article published on February 2004

Stereoselective synthesis and biological evaluation as inhibitors of hepatitis C virus RNA polymerase of GSK3082 analogues with structural diversity at the 5-position

scientific article published on 12 March 2019

Stevia rebaudiana ethanolic extract exerts better antioxidant properties and antiproliferative effects in tumour cells than its diterpene glycoside stevioside.

scientific article published on 13 April 2016

Studying the Allosteric Energy Cycle by Isothermal Titration Calorimetry

scientific article published on 01 January 2012

Targeting intrinsically disordered proteins involved in cancer

scientific article published on 30 October 2019

Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma

scientific article published on 17 November 2019

The Paralogue of the Intrinsically Disordered Nuclear Protein 1 Has a Nuclear Localization Sequence that Binds to Human Importin α3

scientific article published on 08 October 2020

The histidine phosphocarrier protein, HPr, binds to the highly thermostable regulator of sigma D protein, Rsd, and its isolated helical fragments.

scientific article

The intervening domain from MeCP2 enhances the DNA affinity of the methyl binding domain and provides an independent DNA interaction site.

scientific article published on 31 January 2017

Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase

scientific article

Thermal Liquid Biopsy (TLB) Focused on Benign and Premalignant Pancreatic Cyst Diagnosis

scientific article published on 31 December 2020

Thermal Liquid Biopsy (TLB): A Predictive Score Derived from Serum Thermograms as a Clinical Tool for Screening Lung Cancer Patients

scientific article published on 19 July 2019

Thermal liquid biopsy for monitoring melanoma patients under surveillance during treatment: A pilot study

scientific article published on 26 April 2018

Thermodynamically controlled synthesis of amide bonds catalyzed by highly organic solvent-resistant penicillin acylase derivatives.

scientific article published in January 2004

Tinkering with Binding Polynomials in Isothermal Titration Calorimetry

scientific article published on 01 January 2019

Underexposed polar residues and protein stabilization.

scientific article published on 11 October 2010

Unveiling the Binding between the Armadillo-Repeat Domain of Plakophilin 1 and the Intrinsically Disordered Transcriptional Repressor RYBP

scientific article published in 2024

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