List of works - Cyrille Cohen

A TIGIT-based chimeric co-stimulatory switch receptor improves T-cell anti-tumor function

scientific article published on 09 September 2019

A novel lncRNA, GASL1, inhibits cell proliferation and restricts E2F1 activity.

scientific article published on April 2017

An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities.

scientific article

CXCR1 as a novel target for directing reactive T cells toward melanoma: implications for adoptive cell transfer immunotherapy

scientific article published on 24 March 2012

Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition

scientific article published on 22 May 2008

Direct detection and quantitation of a distinct T-cell epitope derived from tumor-specific epithelial cell-associated mucin using human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity

scientific article

Direct visualization of distinct T cell epitopes derived from a melanoma tumor-associated antigen by using human recombinant antibodies with MHC- restricted T cell receptor-like specificity.

scientific article

Durable Complete Response from Metastatic Melanoma after Transfer of Autologous T Cells Recognizing 10 Mutated Tumor Antigens

scientific article published on 16 June 2016

Efficiency of peptide presentation by dendritic cells compared with other cell types: implications for cross-priming.

scientific article published on 11 October 2006

Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity.

scientific article

Engineering T-Cell Specificity Genetically to Generate Anti-melanoma Reactivity

scientific article published on 20 January 2016

Enhanced antitumor activity mediated by human 4‐1BB‐engineered T cells ⬇️

scientific article published on July 16, 2013

Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond.

scientific article

Enhanced receptor expression and in vitro effector function of a murine-human hybrid MART-1-reactive T cell receptor following a rapid expansion

scientific article

Extended presentation of specific MHC-peptide complexes by mature dendritic cells compared to other types of antigen-presenting cells.

scientific article published on June 2004

Fast Image-Guided Stratification Using Anti-Programmed Death Ligand 1 Gold Nanoparticles for Cancer Immunotherapy

scientific article published on 13 October 2017

Generation of recombinant immunotoxins for specific targeting of tumor-related peptides presented by MHC molecules

scientific article published on 01 January 2003

Genetically modulating T-cell function to target cancer.

scientific article published on 24 December 2011

High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation

scientific article

How (specific) would like your T-cells today? Generating T-cell therapeutic function through TCR-gene transfer ⬇️

scientific article (publication date: 2012)

Human T cells engineered to express a programmed death 1/28 costimulatory retargeting molecule display enhanced antitumor activity.

scientific article published on 11 September 2013

In-vitro Optimization of Nanoparticle-Cell Labeling Protocols for In-vivo Cell Tracking Applications

scientific article

Incorporation of transmembrane hydrophobic mutations in the TCR enhance its surface expression and T cell functional avidity.

scientific article published on 27 April 2012

Increased RNA Editing May Provide a Source for Autoantigens in Systemic Lupus Erythematosus.

scientific article published in April 2018

Isolation and characterization of human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells directed toward the widely expressed tumor T-cell epitopes of the telomerase catalyti

scientific article published on 01 June 2002

Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes

scientific article

Isolation, purification and preliminary X-ray characterization of Cpn60-2 (65 kDa heat-shock protein) from Mycobacterium tuberculosis

scientific journal article

MHC-multimer guided isolation of neoepitopes specific T cells as a potent-personalized cancer treatment strategy.

scientific article

Nanomedicine for Cancer Immunotherapy: Tracking Cancer-Specific T-Cells in Vivo with Gold Nanoparticles and CT Imaging.

scientific article published on 11 June 2015

Out of the bitter came forth sweet: Activating CD28-dependent co-stimulation via PD-1 ligands.

scientific article published on January 2014

Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR.

scientific article

Recombinant antibodies with MHC‐restricted, peptide‐specific, T‐cell receptor‐like specificity: new tools to study antigen presentation and TCR–peptide–MHC interactions ⬇️

scientific article published on September 1, 2003

Simple sequence repeats in Escherichia coli: abundance, distribution, composition, and polymorphism

scientific article published on January 2000

Simultaneous monitoring of binding to and activation of tumor-specific T lymphocytes by peptide-MHC.

scientific article

Stable, Nonviral Expression of Mutated Tumor Neoantigen-specific T-cell Receptors Using the Sleeping Beauty Transposon/Transposase System.

scientific article published on 05 March 2016

T-cell receptor gene therapy of established tumors in a murine melanoma model

scientific article

T-cells "à la CAR-T(e)" - Genetically engineering T-cell response against cancer

scientific article published on 14 January 2019

TLR4 Expression Is Associated with Left Ventricular Dysfunction in Patients Undergoing Coronary Artery Bypass Surgery

scientific article published on June 2015

Targeting Multiple Tumors Using T-Cells Engineered to Express a Natural Cytotoxicity Receptor 2-Based Chimeric Receptor.

scientific article

Targeting glycosylated antigens on cancer cells using siglec-7/9-based CAR T-cells

scientific article published on 11 May 2020

The mutational status of p53 can influence its recognition by human T-cells

scientific article published on 31 January 2017

List of works by Cyrille Cohen

A TIGIT-based chimeric co-stimulatory switch receptor improves T-cell anti-tumor function

A novel lncRNA, GASL1, inhibits cell proliferation and restricts E2F1 activity.

An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities.

CXCR1 as a novel target for directing reactive T cells toward melanoma: implications for adoptive cell transfer immunotherapy

Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition

Direct detection and quantitation of a distinct T-cell epitope derived from tumor-specific epithelial cell-associated mucin using human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity

Direct visualization of distinct T cell epitopes derived from a melanoma tumor-associated antigen by using human recombinant antibodies with MHC- restricted T cell receptor-like specificity.

Durable Complete Response from Metastatic Melanoma after Transfer of Autologous T Cells Recognizing 10 Mutated Tumor Antigens

Efficiency of peptide presentation by dendritic cells compared with other cell types: implications for cross-priming.

Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity.

Engineering T-Cell Specificity Genetically to Generate Anti-melanoma Reactivity

Enhanced antitumor activity mediated by human 4‐1BB‐engineered T cells ⬇️

Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond.

Enhanced receptor expression and in vitro effector function of a murine-human hybrid MART-1-reactive T cell receptor following a rapid expansion

Extended presentation of specific MHC-peptide complexes by mature dendritic cells compared to other types of antigen-presenting cells.

Fast Image-Guided Stratification Using Anti-Programmed Death Ligand 1 Gold Nanoparticles for Cancer Immunotherapy

Generation of recombinant immunotoxins for specific targeting of tumor-related peptides presented by MHC molecules

Genetically modulating T-cell function to target cancer.

High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation

How (specific) would like your T-cells today? Generating T-cell therapeutic function through TCR-gene transfer ⬇️

Human T cells engineered to express a programmed death 1/28 costimulatory retargeting molecule display enhanced antitumor activity.

In-vitro Optimization of Nanoparticle-Cell Labeling Protocols for In-vivo Cell Tracking Applications

Incorporation of transmembrane hydrophobic mutations in the TCR enhance its surface expression and T cell functional avidity.

Increased RNA Editing May Provide a Source for Autoantigens in Systemic Lupus Erythematosus.

Isolation and characterization of human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells directed toward the widely expressed tumor T-cell epitopes of the telomerase catalyti

Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes

Isolation, purification and preliminary X-ray characterization of Cpn60-2 (65 kDa heat-shock protein) from Mycobacterium tuberculosis

MHC-multimer guided isolation of neoepitopes specific T cells as a potent-personalized cancer treatment strategy.

Nanomedicine for Cancer Immunotherapy: Tracking Cancer-Specific T-Cells in Vivo with Gold Nanoparticles and CT Imaging.

Out of the bitter came forth sweet: Activating CD28-dependent co-stimulation via PD-1 ligands.

Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR.

Recombinant antibodies with MHC‐restricted, peptide‐specific, T‐cell receptor‐like specificity: new tools to study antigen presentation and TCR–peptide–MHC interactions ⬇️

Simple sequence repeats in Escherichia coli: abundance, distribution, composition, and polymorphism

Simultaneous monitoring of binding to and activation of tumor-specific T lymphocytes by peptide-MHC.

Stable, Nonviral Expression of Mutated Tumor Neoantigen-specific T-cell Receptors Using the Sleeping Beauty Transposon/Transposase System.

T-cell receptor gene therapy of established tumors in a murine melanoma model

T-cells "à la CAR-T(e)" - Genetically engineering T-cell response against cancer

TLR4 Expression Is Associated with Left Ventricular Dysfunction in Patients Undergoing Coronary Artery Bypass Surgery

Targeting Multiple Tumors Using T-Cells Engineered to Express a Natural Cytotoxicity Receptor 2-Based Chimeric Receptor.

Targeting glycosylated antigens on cancer cells using siglec-7/9-based CAR T-cells

The mutational status of p53 can influence its recognition by human T-cells