List of works - Bea Kuiperij

A Practical Guide to Immunoassay Method Validation

scientific article

A multifunctional ELISA to measure oxidised proteins: oxPin1 in Alzheimer's brain as an example

scientific article

Activation of FoxO transcription factors contributes to the antiproliferative effect of cAMP.

scientific article published on March 2005

Addition of MHPG to Alzheimer's disease biomarkers improves differentiation of dementia with Lewy bodies from Alzheimer's disease but not other dementias

scientific article

Amyloid-β oligomer detection by ELISA in cerebrospinal fluid and brain tissue

scientific article published on 26 September 2012

Apolipoprotein D: a potential biomarker for cerebral amyloid angiopathy

scientific article published on 23 December 2019

Biochemistry of the Rap-specific guanine nucleotide exchange factors PDZ-GEF1 and -2.

scientific article published on January 2006

Biomarkers in cerebrospinal fluid for synucleinopathies, tauopathies, and other neurodegenerative disorders.

scientific article published in January 2017

CSF Neurofilament Light Chain but not FLT3 Ligand Discriminates Parkinsonian Disorders.

scientific article published on 5 May 2015

CSF d-serine concentrations are similar in Alzheimer's disease, other dementias, and elderly controls

scientific article published on 23 March 2016

CSF levels of DJ-1 and tau distinguish MSA patients from PD patients and controls

scientific article published on 12 September 2013

CSF levels of glutamine synthetase and GFAP to explore astrocytic damage in seronegative NMOSD

scientific article published on 26 March 2020

Cerebrospinal Fluid Galectin-1 Levels Discriminate Patients with Parkinsonism from Controls

scientific article published on 21 November 2018

Cerebrospinal Fluid NrCAM is not a Suitable Biomarker to Discriminate between Dementia Disorders--A Pilot Study.

scientific article

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

scientific article published on 27 October 2017

Cerebrospinal fluid monocyte chemoattractant protein 1 correlates with progression of Parkinson's disease

scientific article published on 03 September 2020

Cerebrospinal fluid myelin basic protein is elevated in multiple system atrophy

scientific article published on 15 June 2020

Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2

scientific article (publication date: 17 February 2003)

Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor

scientific article

Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease

scientific article published on 01 August 2011

Diagnosis of progressive supranuclear palsy: can measurement of tau forms help? ⬇️

scientific article published on October 13, 2010

Dickkopf-related protein 3 is a potential Aβ-associated protein in Alzheimer's Disease

scientific article

Differential expression of tapasin and immunoproteasome subunits in adenovirus type 5- versus type 12-transformed cells

scientific journal article

Disturbed balance in the expression of MMP9 and TIMP3 in cerebral amyloid angiopathy-related intracerebral haemorrhage

scientific article published on 06 July 2020

Do amyloid β-associated factors co-deposit with Aβ in mouse models for Alzheimer's disease?

scientific article published on January 2010

Identification of cerebrospinal fluid biomarkers for parkinsonism using a proteomics approach

scientific article published on 30 November 2021

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

scientific article published on January 2017

Inflammation biomarker discovery in Parkinson's disease and atypical parkinsonisms

scientific article published on 17 January 2020

Inhibition of α-synuclein aggregation by small heat shock proteins.

scientific article published on 26 August 2011

Levels of HVA, 5-HIAA, and MHPG in the CSF of vascular parkinsonism compared to Parkinson's disease and controls.

scientific article

Limitations of the hCMEC/D3 cell line as a model for Aβ clearance by the human blood-brain barrier.

scientific article published on 11 October 2016

Methods for analysis of amyloid-β aggregates.

scientific article

MicroRNA-29a Is a Candidate Biomarker for Alzheimer's Disease in Cell-Free Cerebrospinal Fluid.

scientific article published on 21 April 2015

MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid.

scientific article published on 17 August 2013

MicroRNAs in Cerebrospinal Fluid as Potential Biomarkers for Parkinson's Disease and Multiple System Atrophy.

scientific article published on 14 November 2016

Multicenter Analytical Validation of Aβ40 Immunoassays.

scientific article

Optimisation of the quantification of glutamine synthetase and myelin basic protein in cerebrospinal fluid by a combined acidification and neutralisation protocol.

scientific article

Plasma Aβ (Amyloid-β) Levels and Severity and Progression of Small Vessel Disease.

scientific article published on 14 March 2018

Protein kinase C-alpha is an upstream activator of the IkappaB kinase complex in the TPA signal transduction pathway to NF-kappaB in U2OS cells.

scientific article published in December 2000

Proteomic profiling of striatal tissue of a rat model of Parkinson's disease after implantation of collagen-encapsulated human umbilical cord mesenchymal stem cells

scientific article published on 16 June 2020

Reduced Influence of apoE on Aβ43 Aggregation and Reduced Vascular Aβ43 Toxicity as Compared with Aβ40 and Aβ42

scientific article published on 17 January 2020

Serpina1 (alpha1-AT) is synthesized in the osteoblastic stem cell niche

scientific article

Serum NFL discriminates Parkinson disease from atypical parkinsonisms

scientific article published on 27 February 2019

TDP-43 plasma levels are higher in amyotrophic lateral sclerosis

scientific article

TDP-43 plasma levels do not differentiate sporadic inclusion body myositis from other inflammatory myopathies

scientific article published on 03 November 2010

Tau Rather than TDP-43 Proteins are Potential Cerebrospinal Fluid Biomarkers for Frontotemporal Lobar Degeneration Subtypes: A Pilot Study.

scientific article published on 23 September 2016

Tau forms in CSF as a reliable biomarker for progressive supranuclear palsy

scientific article published on 18 April 2011

The Nrf2-ARE Signalling pathway: promising drug target to combat oxidative stress in neurodegenerative disorders

scientific article

The diagnostic value of CSF amyloid-β(43) in differentiation of dementia syndromes.

scientific article published in December 2013

The utility of α-synuclein as biofluid marker in neurodegenerative diseases: a systematic review of the literature

scientific article published on 28 August 2015

Total glutamine synthetase levels in cerebrospinal fluid of Alzheimer's disease patients are unchanged

scientific article published on 12 December 2014

Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study

scientific article published on 15 May 2015

Validation of microRNAs in Cerebrospinal Fluid as Biomarkers for Different Forms of Dementia in a Multicenter Study

scientific article published on 16 April 2016

Validation of soluble amyloid-β precursor protein assays as diagnostic CSF biomarkers for neurodegenerative diseases

scientific article published on 7 January 2016

White Matter Hyperintensities are No Major Confounder for Alzheimer's Disease Cerebrospinal Fluid Biomarkers

scientific article published on 21 November 2020

cDNA micro array identification of a gene differentially expressed in adenovirus type 5- versus type 12-transformed cells

scientific article (publication date: 29 December 2000)

List of works by Bea Kuiperij

A Practical Guide to Immunoassay Method Validation

A multifunctional ELISA to measure oxidised proteins: oxPin1 in Alzheimer's brain as an example

Activation of FoxO transcription factors contributes to the antiproliferative effect of cAMP.

Addition of MHPG to Alzheimer's disease biomarkers improves differentiation of dementia with Lewy bodies from Alzheimer's disease but not other dementias

Amyloid-β oligomer detection by ELISA in cerebrospinal fluid and brain tissue

Apolipoprotein D: a potential biomarker for cerebral amyloid angiopathy

Biochemistry of the Rap-specific guanine nucleotide exchange factors PDZ-GEF1 and -2.

Biomarkers in cerebrospinal fluid for synucleinopathies, tauopathies, and other neurodegenerative disorders.

CSF Neurofilament Light Chain but not FLT3 Ligand Discriminates Parkinsonian Disorders.

CSF d-serine concentrations are similar in Alzheimer's disease, other dementias, and elderly controls

CSF levels of DJ-1 and tau distinguish MSA patients from PD patients and controls

CSF levels of glutamine synthetase and GFAP to explore astrocytic damage in seronegative NMOSD

Cerebrospinal Fluid Galectin-1 Levels Discriminate Patients with Parkinsonism from Controls

Cerebrospinal Fluid NrCAM is not a Suitable Biomarker to Discriminate between Dementia Disorders--A Pilot Study.

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

Cerebrospinal fluid monocyte chemoattractant protein 1 correlates with progression of Parkinson's disease

Cerebrospinal fluid myelin basic protein is elevated in multiple system atrophy

Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2

Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor

Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease

Diagnosis of progressive supranuclear palsy: can measurement of tau forms help? ⬇️

Dickkopf-related protein 3 is a potential Aβ-associated protein in Alzheimer's Disease

Differential expression of tapasin and immunoproteasome subunits in adenovirus type 5- versus type 12-transformed cells

Disturbed balance in the expression of MMP9 and TIMP3 in cerebral amyloid angiopathy-related intracerebral haemorrhage

Do amyloid β-associated factors co-deposit with Aβ in mouse models for Alzheimer's disease?

Identification of cerebrospinal fluid biomarkers for parkinsonism using a proteomics approach

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

Inflammation biomarker discovery in Parkinson's disease and atypical parkinsonisms

Inhibition of α-synuclein aggregation by small heat shock proteins.

Levels of HVA, 5-HIAA, and MHPG in the CSF of vascular parkinsonism compared to Parkinson's disease and controls.

Limitations of the hCMEC/D3 cell line as a model for Aβ clearance by the human blood-brain barrier.

Methods for analysis of amyloid-β aggregates.

MicroRNA-29a Is a Candidate Biomarker for Alzheimer's Disease in Cell-Free Cerebrospinal Fluid.

MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid.

MicroRNAs in Cerebrospinal Fluid as Potential Biomarkers for Parkinson's Disease and Multiple System Atrophy.

Multicenter Analytical Validation of Aβ40 Immunoassays.

Optimisation of the quantification of glutamine synthetase and myelin basic protein in cerebrospinal fluid by a combined acidification and neutralisation protocol.

Plasma Aβ (Amyloid-β) Levels and Severity and Progression of Small Vessel Disease.

Protein kinase C-alpha is an upstream activator of the IkappaB kinase complex in the TPA signal transduction pathway to NF-kappaB in U2OS cells.

Proteomic profiling of striatal tissue of a rat model of Parkinson's disease after implantation of collagen-encapsulated human umbilical cord mesenchymal stem cells

Reduced Influence of apoE on Aβ43 Aggregation and Reduced Vascular Aβ43 Toxicity as Compared with Aβ40 and Aβ42

Serpina1 (alpha1-AT) is synthesized in the osteoblastic stem cell niche

Serum NFL discriminates Parkinson disease from atypical parkinsonisms

TDP-43 plasma levels are higher in amyotrophic lateral sclerosis

TDP-43 plasma levels do not differentiate sporadic inclusion body myositis from other inflammatory myopathies

Tau Rather than TDP-43 Proteins are Potential Cerebrospinal Fluid Biomarkers for Frontotemporal Lobar Degeneration Subtypes: A Pilot Study.

Tau forms in CSF as a reliable biomarker for progressive supranuclear palsy

The Nrf2-ARE Signalling pathway: promising drug target to combat oxidative stress in neurodegenerative disorders

The diagnostic value of CSF amyloid-β(43) in differentiation of dementia syndromes.

The utility of α-synuclein as biofluid marker in neurodegenerative diseases: a systematic review of the literature

Total glutamine synthetase levels in cerebrospinal fluid of Alzheimer's disease patients are unchanged

Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study

Validation of microRNAs in Cerebrospinal Fluid as Biomarkers for Different Forms of Dementia in a Multicenter Study

Validation of soluble amyloid-β precursor protein assays as diagnostic CSF biomarkers for neurodegenerative diseases

White Matter Hyperintensities are No Major Confounder for Alzheimer's Disease Cerebrospinal Fluid Biomarkers

cDNA micro array identification of a gene differentially expressed in adenovirus type 5- versus type 12-transformed cells