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List of works by Alberto Ballestrero

5-fluorouracil causes endothelial cell senescence: potential protective role of glucagon-like peptide 1.

scientific article

A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11) in a patient with acute myeloid leukemia

scientific article published on 01 June 2008

A Multi-Scale Approach to Colorectal Cancer: From a Biochemical- Interaction Signaling-Network Level, to Multi-Cellular Dynamics of Malignant Transformation. Interplay with Mutations and Onco-Protein Inhibitor Drugs ⬇️

scientific article published on May 1, 2012

A T315I mutation in e19a2 BCR/ABL1 chronic myeloid leukemia responding to dasatinib.

scientific article published on 5 May 2010

A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation

scientific article published on 05 April 2019

A phase II study of neoadjuvant bevacizumab plus capecitabine and concomitant radiotherapy in patients with locally advanced rectal cancer

scientific article published on 03 January 2012

APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells

scientific article published on 11 May 2015

APO866 activity in hematologic malignancies: a preclinical in vitro study.

scientific article published in June 2009

Adjuvant chemotherapy with high-dose cyclophosphamide, etoposide and cisplatin intensification without progenitor cell support in breast cancer patients with ten or more involved nodes: 5-year results of a pilot trial.

scientific article published in January 2001

Adjuvant high-dose chemotherapy with autologous hematopoietic stem cell support for high-risk primary breast cancer: results from the Italian national registry.

scientific article

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies.

scientific article

Afatinib resistance in non-small cell lung cancer involves the PI3K/AKT and MAPK/ERK signalling pathways and epithelial-to-mesenchymal transition.

scientific article

Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols.

scientific article

Autologous peripheral blood stem cells (PBSC) in breast cancer

scientific article

Bi-weekly docetaxel and gemcitabine regimen in her-2-negative and anthracycline-pretreated metastatic breast cancer patients: a multicenter phase II trial

scientific article published on 16 February 2011

CDKN2A germline mutations are not associated with poor survival in an Italian cohort of melanoma patients

article

Cardiac toxicity of trastuzumab in metastatic breast cancer patients previously treated with high-dose chemotherapy: a retrospective study

scientific article published on April 2006

Clinico-pathological and transcriptomic determinants of SLFN11 expression in invasive breast carcinoma.

scientific article

Clinico-pathological associations and concomitant mutations of the RAS/RAF pathway in metastatic colorectal cancer

scientific article published on 29 April 2019

Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells.

scientific article published on June 2005

Correction to: Schlafen-11 expression is associated with immune signatures and basal-like phenotype in breast cancer

scientific article published on 01 October 2019

Correction: Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations.

scientific article published on 19 June 2018

DNA aneuploidy relationship with patient age and tobacco smoke in OPMDs/OSCCs

scientific article published on 6 September 2017

DNA damage response pathways and cell cycle checkpoints in colorectal cancer: current concepts and future perspectives for targeted treatment.

scientific article published on May 2012

Discontinuation of first-line bevacizumab in metastatic colorectal cancer: the BEAWARE Italian Observational Study

scientific article published on 11 March 2019

Dose-dense vinorelbine and paclitaxel with granulocyte colony-stimulating factor in metastatic breast cancer patients: anti-tumor activity and peripheral blood progenitor cell mobilization capability.

scientific article

Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status.

scientific article published on 10 June 2016

Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments: concordance with experimental results.

scientific article published on November 2010

EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition

scientific article

Effect of different cytokines on mammaglobin and maspin gene expression in normal leukocytes: possible relevance to the assays for the detection of micrometastatic breast cancer.

scientific article published in May 2005

Effects of three cytokine regimens on hematologic recovery and progenitor cell mobilization after high-dose cyclophosphamide, etoposide, and cisplatin.

scientific article published in June 2000

Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis.

scientific article published on 21 December 2004

Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells

scientific article published on 16 December 2015

Extracellular cytolysis by leukaemic blast cells ⬇️

scientific article published on 01 January 1984

Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition.

scientific article published in May 2015

Four-step high-dose sequential chemotherapy with double hematopoietic progenitor-cell rescue for metastatic breast cancer

scientific article

Frailty assessment in elective gastrointestinal oncogeriatric surgery: Predictors of one-year mortality and functional status

scientific article published on 07 May 2019

Germline mutations in the von Hippel-Lindau gene in Italian patients.

scientific article published on 21 May 2009

Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression

scientific article

HMGA2 overexpression in polycythemia vera with t(12;21)(q14;q22)

scientific article published on 01 September 2007

Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases.

scientific article

Heterogeneity and frequency of BRAF mutations in primary melanoma: Comparison between molecular methods and immunohistochemistry

scientific article published on 22 December 2016

High frequency of trisomy 8 in acute promyelocytic leukemia: a fluorescence in situ hybridization study.

scientific article published on September 1997

High-dose mitoxantrone with peripheral blood progenitor cell rescue: toxicity, pharmacokinetics and implications for dosage and schedule ⬇️

scientific article published on January 1, 1997

Histone deacetylase inhibitors affect dendritic cell differentiation and immunogenicity

scientific article published on 01 July 2007

Integrated Somatic and Germline Whole-Exome Sequencing Analysis in Women with Lung Cancer after a Previous Breast Cancer.

scientific article published on 28 March 2019

Kinase domain mutations of BCR-ABL identified at diagnosis before imatinib-based therapy are associated with progression in patients with high Sokal risk chronic phase chronic myeloid leukemia.

scientific article published in February 2010

Long-term survival in patients with metastatic breast cancer receiving intensified chemotherapy and stem cell rescue: data from the Italian registry.

scientific article

Low percentage of KRAS mutations revealed by locked nucleic acid polymerase chain reaction: implications for treatment of metastatic colorectal cancer

scientific article published on January 2012

Matrix metalloproteinase-2 and -9 are induced differently by doxorubicin in H9c2 cells: The role of MAP kinases and NAD(P)H oxidase.

scientific article published on 6 October 2005

Molecular characterization of an Italian series of sporadic GISTs.

scientific article

Neoadjuvant letrozole plus taselisib versus letrozole plus placebo in postmenopausal women with oestrogen receptor-positive, HER2-negative, early-stage breast cancer (LORELEI): a multicentre, randomised, double-blind, placebo-controlled, phase 2 tri

scientific article published on 08 August 2019

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

scientific article published on 7 November 2013

Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity

scientific article

Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair

scientific article

Parameter space exploration within dynamic simulations of signaling networks.

scientific article published in February 2013

Patient-Tailored Treatments with Anti-EGFR Monoclonal Antibodies in Advanced Colorectal Cancer: KRAS and Beyond ⬇️

scientific article published on May 1, 2012

Prospective study to optimize care and improve knowledge on ovarian function and/or fertility preservation in young breast cancer patients: Results of the pilot phase of the PREgnancy and FERtility (PREFER) study

scientific article published on 22 June 2018

Proteasome inhibitor-induced apoptosis in human monocyte-derived dendritic cells.

scientific article published in March 2006

Proteasome inhibitors as immunosuppressants: biological rationale and clinical experience.

scientific article published on July 2012

Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents

scientific article

Quantitative Real Time PCR assessment of hormonal receptors and HER2 status on fine-needle aspiration pre-operatory specimens from a prospectively accrued cohort of women with suspect breast malignant lesions

scientific article

Rejuvenating sirtuins: the rise of a new family of cancer drug targets

scientific article

Reliability and reproducibility of a RNA preamplification method for low-density array analysis from formalin-fixed paraffin-embedded breast cancer samples.

scientific article published on June 2009

Report on the first SLFN11 monothematic workshop: from function to role as a biomarker in cancer

scientific article published on 2 October 2017

Reverse-transcriptase polymerase chain reaction of the maspin gene in the detection of bone marrow breast carcinoma cell contamination

scientific article published in 2001

Role of angiogenesis inhibitors in colorectal cancer: sensitive and insensitive tumors.

scientific article published on May 2012

Schlafen-11 expression is associated with immune signatures and basal-like phenotype in breast cancer

scientific article published on 20 June 2019

Sequential dose-dense 5-fluorouracil, epirubicin and cyclophosphamide followed by docetaxel in patients with early breast cancer with four or more positive lymph nodes

scientific article published in March 2014

Specific conjunctival challenge in polysensitized subjects

scientific article published on 01 September 1997

Squalene epoxidase as a promising metabolic target in cancer treatment

scientific article published on 27 March 2018

Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer

scientific article

Squamous cell carcinoma of the breast: a case report.

scientific article published on 10 July 2009

Standard-dose recombinant human granulocyte colony-stimulating factor (rhG-CSF) allows safe and repeated administration of high-dose cyclophosphamide, etoposide, and cisplatin (CEP)

scientific article published on 01 June 1997

Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer.

scientific article published on May 2012

Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial.

scientific article published on 30 May 2016

The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level.

scientific article published on 28 March 2016

The NAD+-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells by Regulating Ca2+ Responses ⬇️

scientific article published on October 18, 2012

The effect of preoperative chemoradiotherapy on lymph nodes harvested in TME for rectal cancer.

scientific article

The induction of distinct cytokine cascades correlates with different effects of granulocyte-colony stimulating factor and granulocyte/macrophage-colony-stimulating factor on the lymphocyte compartment in the course of high-dose chemotherapy for bre

scientific article published on 01 September 1999

The use of dendritic cells in cancer immunotherapy

scientific article published on 04 December 2007

Tracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status ⬇️

scientific article published on September 5, 2012

Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells.

scientific article published in February 2004

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