List of works by Sw W. Spiekstra

A potential in vitro epidermal equivalent assay to determine sensitizer potency

scientific article published on 19 October 2010

Allergens of permanent hair dyes induces epidermal damage, skin barrier loss and IL-1 α increase in epidermal in vitro model.

scientific article published on 19 December 2017

Assessment of metal sensitizer potency with the reconstructed human epidermis IL-18 assay.

scientific article published on 24 October 2017

Assessment of preferential T-helper 1 or T-helper 2 induction by low molecular weight compounds using the local lymph node assay in conjunction with RT-PCR and ELISA for interferon-gamma and interleukin-4

scientific article

Autologous full-thickness skin substitute for healing chronic wounds.

scientific article published on August 2006

CCL5 and CCL20 mediate immigration of Langerhans cells into the epidermis of full thickness human skin equivalents.

scientific article

Comparison of the skin sensitization potential of 3 red and 2 black tattoo inks using interleukin-18 as a biomarker in a reconstructed human skin model

scientific article published on 22 August 2018

Cytokine and chemokine release upon prolonged mechanical loading of the epidermis.

scientific article

Dendritic cell migration assay: a potential prediction model for identification of contact allergens.

scientific article

Determination of the sensitising activity of the rubber contact sensitisers TMTD, ZDMC, MBT and DEA in a modified local lymph node assay and the effect of sodium dodecyl sulfate pretreatment on local lymph node responses.

scientific article

Development of a Full-Thickness Human Gingiva Equivalent Constructed from Immortalized Keratinocytes and Fibroblasts

scientific article published on 12 July 2016

Gingiva Equivalents Secrete Negligible Amounts of Key Chemokines Involved in Langerhans Cell Migration Compared to Skin Equivalents

scientific article published on 11 October 2015

Immune-competent human skin disease models.

scientific article published on 2 June 2016

In vitro exposure effects of cyclosporin A and bis(tri-n-butyltin)oxide on lymphocyte proliferation, cytokine (receptor) mRNA expression, and cell surface marker expression in rat thymocytes and splenocytes

scientific article

Induction of cytokine (interleukin-1alpha and tumor necrosis factor-alpha) and chemokine (CCL20, CCL27, and CXCL8) alarm signals after allergen and irritant exposure.

scientific article

Inter-laboratory study of the in vitro dendritic cell migration assay for identification of contact allergens.

scientific article published on 4 October 2011

International ring trial of the epidermal equivalent sensitizer potency assay: reproducibility and predictive-capacity.

scientific article published on 17 February 2014

MUTZ-3 Langerhans cell maturation and CXCL12 independent migration in reconstructed human gingiva.

scientific article published on 19 May 2016

MUTZ-3 derived Langerhans cells in human skin equivalents show differential migration and phenotypic plasticity after allergen or irritant exposure.

scientific article published on 29 May 2015

Technical advance: Langerhans cells derived from a human cell line in a full-thickness skin equivalent undergo allergen-induced maturation and migration.

scientific article published on 22 June 2011

Transfer of a two-tiered keratinocyte assay: IL-18 production by NCTC2544 to determine the skin sensitizing capacity and epidermal equivalent assay to determine sensitizer potency.

scientific article

Wound-healing factors secreted by epidermal keratinocytes and dermal fibroblasts in skin substitutes.

scientific article

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