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List of works by Magdalena Villarroya

An Alternative Homodimerization Interface of MnmG Reveals a Conformational Dynamics that Is Essential for Its tRNA Modification Function

scientific article published on 02 June 2018

Bacillus subtilis exhibits MnmC-like tRNA modification activities.

scientific article

Defective Expression of the Mitochondrial-tRNA Modifying Enzyme GTPBP3 Triggers AMPK-Mediated Adaptive Responses Involving Complex I Assembly Factors, Uncoupling Protein 2, and the Mitochondrial Pyruvate Carrier

scientific article published on 7 December 2015

Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARγ-UCP2-AMPK axis.

scientific article published on 18 January 2018

Effects of mutagenesis in the switch I region and conserved arginines of Escherichia coli MnmE protein, a GTPase involved in tRNA modification.

scientific article published on 27 June 2005

Enzymology of tRNA modification in the bacterial MnmEG pathway.

scientific article published on 28 February 2012

Modification of the wobble uridine in bacterial and mitochondrial tRNAs reading NNA/NNG triplets of 2-codon boxes

scientific article

Mutations in the Caenorhabditis elegans orthologs of human genes required for mitochondrial tRNA modification cause similar electron transport chain defects but different nuclear responses.

scientific article published on 21 July 2017

Structure-Function Analysis of Escherichia coli MnmG (GidA), a Highly Conserved tRNA-Modifying Enzyme

scientific article

The Escherichia coli RlmN methyltransferase is a dual-specificity enzyme that modifies both rRNA and tRNA and controls translational accuracy.

scientific article

The GTPase activity and C-terminal cysteine of the Escherichia coli MnmE protein are essential for its tRNA modifying function.

scientific article published on 30 April 2003

The MELAS mutation m.3243A>G alters the expression of mitochondrial tRNA fragments

scientific article published on 11 June 2019

The MELAS mutation m.3243A>G promotes reactivation of fetal cardiac genes and an epithelial-mesenchymal transition-like program via dysregulation of miRNAs

scientific article published on 19 June 2018

The tRNA-modifying function of MnmE is controlled by post-hydrolysis steps of its GTPase cycle ⬇️

scientific article published on April 28, 2013

microRNA-mediated differential expression of TRMU, GTPBP3 and MTO1 in cell models of mitochondrial-DNA diseases

scientific article

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