List of works - Michel Espinoza-Fonseca

Aromatic-aromatic interactions in the formation of the MDM2-p53 complex

scientific article published on 18 March 2008

Atomic-level mechanisms for phospholamban regulation of the calcium pump.

scientific article

Backbone conformational preferences of an intrinsically disordered protein in solution.

scientific article published on 13 April 2012

Docking and quantum mechanic studies on cholinesterases and their inhibitors

scientific article published on 19 October 2006

Dynamic optimization of signal transductionvia intrinsic disorder ⬇️

scientific article published on November 14, 2011

Effect of a M1 allosteric modulator on scopolamine-induced amnesia.

scientific article published in January 2007

Effects of pseudophosphorylation mutants on the structural dynamics of smooth muscle myosin regulatory light chain.

scientific article published on October 2014

Exploring the possible binding sites at the interface of triosephosphate isomerase dimer as a potential target for anti-tripanosomal drug design.

scientific article published in June 2004

Fully flexible docking models of the complex between alpha7 nicotinic receptor and a potent heptapeptide inhibitor of the beta-amyloid peptide binding

scientific article published on 18 April 2006

Identification of multiple allosteric sites on the M1 muscarinic acetylcholine receptor.

scientific article published on 21 November 2005

Knowledgebase for addiction-related genes: is it possible an extrapolation to rational multi-target drug design?

scientific article published on 7 September 2008

Leucine-rich hydrophobic clusters promote folding of the N-terminus of the intrinsically disordered transactivation domain of p53.

scientific article published on 20 January 2009

Microsecond molecular dynamics simulations of Mg²⁺- and K⁺-bound E1 intermediate states of the calcium pump

scientific article

Molecular docking of four beta-amyloid1-42 fragments on the alpha7 nicotinic receptor: delineating the binding site of the Abeta peptides.

scientific article published in October 2004

Molecular dynamics simulations reveal a disorder-to-order transition on phosphorylation of smooth muscle myosin.

scientific article

Phosphorylation-induced structural changes in smooth muscle myosin regulatory light chain

scientific article

Preexisting domain motions underlie protonation-dependent structural transitions of the P-type Ca2+-ATPase.

scientific article published in April 2017

Reconciling binding mechanisms of intrinsically disordered proteins.

scientific article published on 03 March 2009

Structural basis for relief of phospholamban-mediated inhibition of the sarcoplasmic reticulum Ca2+-ATPase at saturating Ca2+ conditions

scientific article published on 22 June 2018

Structural considerations for the rational design of selective anti-trypanosomal agents: the role of the aromatic clusters at the interface of triosephosphate isomerase dimer.

scientific article published in March 2005

Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives.

scientific article published in May 2003

Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer

scientific article

The Ca2+-ATPase pump facilitates bidirectional proton transport across the sarco/endoplasmic reticulum.

scientific article published on 14 March 2017

The benefits of the multi-target approach in drug design and discovery

scientific article published on 03 October 2005

Thermodynamic and structural basis of phosphorylation-induced disorder-to-order transition in the regulatory light chain of smooth muscle myosin.

scientific article published on 21 August 2008

Toward a rational design of selective multi-trypanosomatid inhibitors: a computational docking study

scientific article published on 25 September 2006

Transient stability of the helical pattern of region F19-L22 of the N-terminal domain of p53: a molecular dynamics simulation study

scientific article published on 03 March 2006

Tyr74 is essential for the formation, stability and function of Plasmodium falciparum triosephosphate isomerase dimer.

scientific article published on 13 November 2009

p-Aminobenzoic acid derivatives as acetylcholinesterase inhibitors.

scientific article published on 25 April 2005

List of works by Michel Espinoza-Fonseca

Aromatic-aromatic interactions in the formation of the MDM2-p53 complex

Atomic-level mechanisms for phospholamban regulation of the calcium pump.

Backbone conformational preferences of an intrinsically disordered protein in solution.

Docking and quantum mechanic studies on cholinesterases and their inhibitors

Dynamic optimization of signal transductionvia intrinsic disorder ⬇️

Effect of a M1 allosteric modulator on scopolamine-induced amnesia.

Effects of pseudophosphorylation mutants on the structural dynamics of smooth muscle myosin regulatory light chain.

Exploring the possible binding sites at the interface of triosephosphate isomerase dimer as a potential target for anti-tripanosomal drug design.

Fully flexible docking models of the complex between alpha7 nicotinic receptor and a potent heptapeptide inhibitor of the beta-amyloid peptide binding

Identification of multiple allosteric sites on the M1 muscarinic acetylcholine receptor.

Knowledgebase for addiction-related genes: is it possible an extrapolation to rational multi-target drug design?

Leucine-rich hydrophobic clusters promote folding of the N-terminus of the intrinsically disordered transactivation domain of p53.

Microsecond molecular dynamics simulations of Mg²⁺- and K⁺-bound E1 intermediate states of the calcium pump

Molecular docking of four beta-amyloid1-42 fragments on the alpha7 nicotinic receptor: delineating the binding site of the Abeta peptides.

Molecular dynamics simulations reveal a disorder-to-order transition on phosphorylation of smooth muscle myosin.

Phosphorylation-induced structural changes in smooth muscle myosin regulatory light chain

Preexisting domain motions underlie protonation-dependent structural transitions of the P-type Ca2+-ATPase.

Reconciling binding mechanisms of intrinsically disordered proteins.

Structural basis for relief of phospholamban-mediated inhibition of the sarcoplasmic reticulum Ca2+-ATPase at saturating Ca2+ conditions

Structural considerations for the rational design of selective anti-trypanosomal agents: the role of the aromatic clusters at the interface of triosephosphate isomerase dimer.

Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives.

Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer

The Ca2+-ATPase pump facilitates bidirectional proton transport across the sarco/endoplasmic reticulum.

The benefits of the multi-target approach in drug design and discovery

Thermodynamic and structural basis of phosphorylation-induced disorder-to-order transition in the regulatory light chain of smooth muscle myosin.

Toward a rational design of selective multi-trypanosomatid inhibitors: a computational docking study

Transient stability of the helical pattern of region F19-L22 of the N-terminal domain of p53: a molecular dynamics simulation study

Tyr74 is essential for the formation, stability and function of Plasmodium falciparum triosephosphate isomerase dimer.

p-Aminobenzoic acid derivatives as acetylcholinesterase inhibitors.