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List of works by Jila Sadeghi

A direct time-based ITC approach for substrate turnover measurements demonstrated on human FMO3

scientific article published on 01 May 2019

A nucleotidase with unique catalytic properties is secreted by Trichinella spiralis.

scientific article

A rapid screening for cytochrome P450 catalysis on new chemical entities: cytochrome P450 BM3 and 1,2,5-oxadiazole derivatives

scientific article published on 13 September 2012

An electrochemical microfluidic platform for human P450 drug metabolism profiling.

scientific article published on 24 November 2010

Breakthrough in P450 bioelectrochemistry and future perspectives.

scientific article published on 18 July 2010

CYP116B5: a new class VII catalytically self-sufficient cytochrome P450 from Acinetobacter radioresistens that enables growth on alkanes

scientific article published on 30 December 2014

Characterisation of the electron transfer and complex formation between flavodoxin from D. vulgaris and the haem domain of cytochrome P450 BM3 from B. megaterium.

scientific article published on 30 January 2009

Characterization of a new Baeyer-Villiger monooxygenase and conversion to a solely N-or S-oxidizing enzyme by a single R292 mutation

scientific article published on 22 June 2016

Chimeric P450 enzymes: activity of artificial redox fusions driven by different reductases for biotechnological applications.

scientific article published on January 2013

Comparison of the refined crystal structures of wild-type (1.34 Å) flavodoxin fromDesulfovibrio vulgarisand the S35C mutant (1.44 Å) at 100 K

scientific article published on 28 September 2002

Control of human cytochrome P450 2E1 electrocatalytic response as a result of unique orientation on gold electrodes.

scientific article published in June 2010

Cytochrome P450 ubiquitination: branding for the proteolytic slaughter?

scientific article

Direct electrochemistry of an [FeFe]-hydrogenase on a TiO2 Electrode

scientific article published in 2011

Drug–drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4

scientific article published in August 2012

Dynamics and flexibility of human aromatase probed by FTIR and time resolved fluorescence spectroscopy

scientific article

Effect of Human Flavin-Containing Monooxygenase 3 Polymorphism on the Metabolism of Aurora Kinase Inhibitors

scientific article published on January 28, 2013

Effects of protein-protein interactions on electron transfer: docking and electron transfer calculations for complexes between flavodoxin and c-type cytochromes

scientific article published in July 1999

Electrochemical detection of human cytochrome P450 2A6 inhibition: a step toward reducing dependence on smoking

scientific article published on 14 February 2014

Electrochemistry of Canis familiaris cytochrome P450 2D15 with gold nanoparticles: An alternative to animal testing in drug discovery.

scientific article published on 12 June 2015

Engineering Macaca fascicularis cytochrome P450 2C20 to reduce animal testing for new drugs.

scientific article published on 7 June 2012

Engineering and design in the bioelectrochemistry of metalloproteins.

scientific article

Engineering multi-domain redox proteins containing flavodoxin as bio-transformer: preparatory studies by rational design

scientific article published in September 1998

Entrapment of human flavin-containing monooxygenase 3 in the presence of gold nanoparticles: TEM, FTIR and electrocatalysis.

scientific article published on 2 October 2012

Escherichia coli Overexpressing a Baeyer-Villiger Monooxygenase from Acinetobacter radioresistens Becomes Resistant to Imipenem.

scientific article

Fluorescence detection of ligand binding to labeled cytochrome P450BM3

scientific article published in 2012

Graphene oxide-mediated electrochemistry of glucose oxidase on glassy carbon electrodes.

scientific article published on 14 July 2015

Human Cytochrome P450 3A4 as a Biocatalyst: Effects of the Engineered Linker in Modulation of Coupling Efficiency in 3A4-BMR Chimeras

scientific article published on 21 March 2017

Human flavin-containing monooxygenase 3 on graphene oxide for drug metabolism screening.

scientific article

Human flavin-containing monooxygenase 3: Structural mapping of gene polymorphisms and insights into molecular basis of drug binding.

scientific article

Hydrogen production at high Faradaic efficiency by a bio-electrode based on TiO2 adsorption of a new [FeFe]-hydrogenase from Clostridium perfringens.

scientific article published on 11 August 2015

Identification of a novel Baeyer‐Villiger monooxygenase from Acinetobacter radioresistens: close relationship to the Mycobacterium tuberculosis prodrug activator EtaA

scientific article published on August 2, 2012

Identification of human flavin-containing monooxygenase 3 substrates by a colorimetric screening assay.

scientific article published on 27 January 2017

In vitro drug metabolism by C-terminally truncated human flavin-containing monooxygenase 3.

scientific article

Ionic strength dependence of the non-physiological electron transfer between flavodoxin and cytochrome c 553 from D. vulgaris

scientific article published in November 2000

Iron-based redox centres of reductase and oxygenase components of phenol hydroxylase from A. radioresistens: a redox chain working at highly positive redox potentials

scientific article published in 2012

Laser-written nanoporous silicon diffraction gratings for biosensors

scientific article

Layer-by-Layer Assembly of Supported Lipid Bilayer Poly-L-Lysine Multilayers.

scientific article published on 7 December 2015

Mediated electrochemistry of peroxidases—effects of variations in protein and mediator structures

scientific article published in December 1997

Molecular Lego: design of molecular assemblies of P450 enzymes for nanobiotechnology

scientific article published in January 2002

P450-based porous silicon biosensor for arachidonic acid detection

scientific article published on 22 July 2011

Protein and electrode engineering for the covalent immobilization of P450 BMP on gold.

scientific article

Subtle structural changes in the Asp251Gly/Gln307His P450 BM3 mutant responsible for new activity toward diclofenac, tolbutamide and ibuprofen

scientific article

Tuning the reduction potential of engineered cytochrome c-553.

scientific article published in July 2002

Understanding uncoupling in the multiredox centre P450 3A4–BMR model system

scientific article published on 21 September 2010