List of works - Wataru Ikeda

ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions

scientific article

Association of frabin with specific actin and membrane structures.

scientific article published on April 2002

Binding between the junctional proteins afadin and PLEKHA7 and implication in the formation of adherens junction in epithelial cells.

scientific article

Blockade of the fractalkine-CX3CR1 axis ameliorates experimental colitis by dislodging venous crawling monocytes

Cataract-preventing contact lens for in vivo imaging of mouse retina

scientific article published on 01 August 2018

Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation

scientific article (publication date: 14 June 2001)

Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse

scientific article (publication date: 21 February 2003)

Identification of splicing variants of Frabin with partly different functions and tissue distribution

scientific article (publication date: 7 September 2001)

Imaging Window Device for Subcutaneous Implantation Tumor

scientific article published on 01 January 2018

Inhibition of cell movement and proliferation by cell-cell contact-induced interaction of Necl-5 with nectin-3

scientific article

Interaction and localization of Necl-5 and PDGF receptor beta at the leading edges of moving NIH3T3 cells: Implications for directional cell movement.

scientific article published on March 2008

Interaction of Nectin-like Molecule 2 with Integrin α6β4 and Inhibition of Disassembly of Integrin α6β4 from Hemidesmosomes ⬇️

scientific article published on August 31, 2011

Interaction of cancer cells with platelets mediated by Necl-5/poliovirus receptor enhances cancer cell metastasis to the lungs.

scientific article

Interaction of integrin alpha(6)beta(4) with ErbB3 and implication in heregulin-induced ErbB3/ErbB2-mediated DNA synthesis.

scientific article published on 29 July 2010

Involvement of the interaction of afadin with ZO-1 in the formation of tight junctions in Madin-Darby canine kidney cells

scientific article

Involvement of up-regulated Necl-5/Tage4/PVR/CD155 in the loss of contact inhibition in transformed NIH3T3 cells.

scientific article published on 29 November 2006

Mechanisms of activation and action of mDial in the formation of parallel stress fibers in MDCK cells.

scientific article published on July 2000

Necl-5/PVR enhances PDGF-induced attraction of growing microtubules to the plasma membrane of the leading edge of moving NIH3T3 cells.

scientific article published on 21 October 2010

Necl-5/poliovirus receptor interacts in cis with integrin alphaVbeta3 and regulates its clustering and focal complex formation

scientific article

Nectin Couples Cell-Cell Adhesion and the Actin Scaffold at Heterotypic Testicular Junctions

scientific article published on 01 July 2002

Nectin and junctional adhesion molecule are critical cell adhesion molecules for the apico-basal alignment of adherens and tight junctions in epithelial cells.

scientific article published on 24 September 2013

Nectin-dependent localization of ZO-1 at puncta adhaerentia junctions between the mossy fiber terminals and the dendrites of the pyramidal cells in the CA3 area of adult mouse hippocampus.

scientific article published in June 2003

Nectin-like molecule-1/TSLL1/SynCAM3: a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes.

scientific article

Nectin-like molecule-5/Tage4 enhances cell migration in an integrin-dependent, Nectin-3-independent manner.

scientific article published on 9 February 2004

Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization.

scientific article

Novel role of nectin: implication in the co-localization of JAM-A and claudin-1 at the same cell-cell adhesion membrane domain.

scientific article

Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues.

scientific article published in April 2018

Rab13 Small G Protein and Junctional Rab13-binding Protein (JRAB) Orchestrate Actin Cytoskeletal Organization during Epithelial Junctional Development ⬇️

scientific article published on October 24, 2012

Regulation of platelet-derived growth factor-induced Ras signaling by poliovirus receptor Necl-5 and negative growth regulator Sprouty2.

scientific article published on March 2007

Requirement of interaction of nectin-1alpha/HveC with afadin for efficient cell-cell spread of herpes simplex virus type 1.

scientific article published on May 2001

Restoration of E-cadherin-based cell-cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line.

scientific article

Role of Anti-Fractalkine Antibody in Suppression of Joint Destruction by Inhibiting Migration of Osteoclast Precursors to the Synovium in Experimental Arthritis

scientific article published on 01 February 2019

Roles and modes of action of nectins in cell-cell adhesion.

scientific article

Roles of Necl-5/poliovirus receptor and Rho-associated kinase (ROCK) in the regulation of transformation of integrin alpha(V)beta(3)-based focal complexes into focal adhesions.

scientific article

Roles of cell adhesion molecules nectin and nectin-like molecule-5 in the regulation of cell movement and proliferation.

scientific article published on September 2008

Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells.

scientific article published on 17 April 2008

Structure and Expression of the Human SM22 Gene, Assignment of the Gene to Chromosome 11, and Repression of the Promoter Activity by Cytosine DNA Methylation ⬇️

scientific article (publication date: July 1997)

Tage4/Nectin-like molecule-5 heterophilically trans-interacts with cell adhesion molecule Nectin-3 and enhances cell migration

scientific journal article

The immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin.

scientific article published on January 2008

Transcriptional activation of the mouse Necl-5/Tage4/PVR/CD155 gene by fibroblast growth factor or oncogenic Ras through the Raf-MEK-ERK-AP-1 pathway.

scientific article

List of works by Wataru Ikeda

ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions

Association of frabin with specific actin and membrane structures.

Binding between the junctional proteins afadin and PLEKHA7 and implication in the formation of adherens junction in epithelial cells.

Blockade of the fractalkine-CX3CR1 axis ameliorates experimental colitis by dislodging venous crawling monocytes

Cataract-preventing contact lens for in vivo imaging of mouse retina

Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation

Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse

Identification of splicing variants of Frabin with partly different functions and tissue distribution

Imaging Window Device for Subcutaneous Implantation Tumor

Inhibition of cell movement and proliferation by cell-cell contact-induced interaction of Necl-5 with nectin-3

Interaction and localization of Necl-5 and PDGF receptor beta at the leading edges of moving NIH3T3 cells: Implications for directional cell movement.

Interaction of Nectin-like Molecule 2 with Integrin α6β4 and Inhibition of Disassembly of Integrin α6β4 from Hemidesmosomes ⬇️

Interaction of cancer cells with platelets mediated by Necl-5/poliovirus receptor enhances cancer cell metastasis to the lungs.

Interaction of integrin alpha(6)beta(4) with ErbB3 and implication in heregulin-induced ErbB3/ErbB2-mediated DNA synthesis.

Involvement of the interaction of afadin with ZO-1 in the formation of tight junctions in Madin-Darby canine kidney cells

Involvement of up-regulated Necl-5/Tage4/PVR/CD155 in the loss of contact inhibition in transformed NIH3T3 cells.

Mechanisms of activation and action of mDial in the formation of parallel stress fibers in MDCK cells.

Necl-5/PVR enhances PDGF-induced attraction of growing microtubules to the plasma membrane of the leading edge of moving NIH3T3 cells.

Necl-5/poliovirus receptor interacts in cis with integrin alphaVbeta3 and regulates its clustering and focal complex formation

Nectin Couples Cell-Cell Adhesion and the Actin Scaffold at Heterotypic Testicular Junctions

Nectin and junctional adhesion molecule are critical cell adhesion molecules for the apico-basal alignment of adherens and tight junctions in epithelial cells.

Nectin-dependent localization of ZO-1 at puncta adhaerentia junctions between the mossy fiber terminals and the dendrites of the pyramidal cells in the CA3 area of adult mouse hippocampus.

Nectin-like molecule-1/TSLL1/SynCAM3: a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule localizing at non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes.

Nectin-like molecule-5/Tage4 enhances cell migration in an integrin-dependent, Nectin-3-independent manner.

Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization.

Novel role of nectin: implication in the co-localization of JAM-A and claudin-1 at the same cell-cell adhesion membrane domain.

Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues.

Rab13 Small G Protein and Junctional Rab13-binding Protein (JRAB) Orchestrate Actin Cytoskeletal Organization during Epithelial Junctional Development ⬇️

Regulation of platelet-derived growth factor-induced Ras signaling by poliovirus receptor Necl-5 and negative growth regulator Sprouty2.

Requirement of interaction of nectin-1alpha/HveC with afadin for efficient cell-cell spread of herpes simplex virus type 1.

Restoration of E-cadherin-based cell-cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line.

Role of Anti-Fractalkine Antibody in Suppression of Joint Destruction by Inhibiting Migration of Osteoclast Precursors to the Synovium in Experimental Arthritis

Roles and modes of action of nectins in cell-cell adhesion.

Roles of Necl-5/poliovirus receptor and Rho-associated kinase (ROCK) in the regulation of transformation of integrin alpha(V)beta(3)-based focal complexes into focal adhesions.

Roles of cell adhesion molecules nectin and nectin-like molecule-5 in the regulation of cell movement and proliferation.

Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells.

Structure and Expression of the Human SM22 Gene, Assignment of the Gene to Chromosome 11, and Repression of the Promoter Activity by Cytosine DNA Methylation ⬇️

Tage4/Nectin-like molecule-5 heterophilically trans-interacts with cell adhesion molecule Nectin-3 and enhances cell migration

The immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin.

Transcriptional activation of the mouse Necl-5/Tage4/PVR/CD155 gene by fibroblast growth factor or oncogenic Ras through the Raf-MEK-ERK-AP-1 pathway.