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List of works by Philippe Lory

5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone.

scientific article published on 11 December 2013

A Ca(v)3.2/syntaxin-1A signaling complex controls T-type channel activity and low-threshold exocytosis

scientific article

A Recurrent Mutation in CACNA1G Alters Cav3.1 T-Type Calcium-Channel Conduction and Causes Autosomal-Dominant Cerebellar Ataxia

scientific journal article

A destructive interaction mechanism accounts for dominant-negative effects of misfolded mutants of voltage-gated calcium channels.

scientific article

A novel phospho-modulatory mechanism contributes to the calcium-dependent regulation of T-type Ca2+ channels

scientific article published on 30 October 2019

A role for voltage gated T-type calcium channels in mediating "capacitative" calcium entry?

scientific article published on 26 January 2006

Acceleration of activation and inactivation by the β subunit of the skeletal muscle calcium channel ⬇️

scientific article published on July 11, 1991

Activity-dependent regulation of T-type calcium channels by submembrane calcium ions

scientific article published on 21 January 2017

Alternatively spliced alpha(1G) (Ca(V)3.1) intracellular loops promote specific T-type Ca(2+) channel gating properties.

scientific article published on March 2001

Antisense depletion of beta-subunits fails to affect T-type calcium channels properties in a neuroblastoma cell line.

scientific article published on June 1998

Blockade of T-type calcium channels prevents tonic-clonic seizures in a maximal electroshock seizure model

scientific article published on 9 October 2015

Bradycardia and slowing of the atrioventricular conduction in mice lacking CaV3.1/alpha1G T-type calcium channels

scientific journal article

Ca(v)3.2 calcium channels control an autocrine mechanism that promotes neuroblastoma cell differentiation.

scientific article published on March 2004

Calcium channelopathies in inherited neurological disorders: relevance to drug screening for acquired channel disorders.

scientific article published on July 2010

Cell cycle dependent toxicity of an amphiphilic synthetic peptide ⬇️

scientific article published on November 24, 1997

Characterization of the dominant inheritance mechanism of Episodic Ataxia type 2.

scientific article published on 5 July 2017

Chemical determinants involved in anandamide-induced inhibition of T-type calcium channels.

scientific article published on 22 November 2006

Cross-modulation and molecular interaction at the Cav3.3 protein between the endogenous lipids and the T-type calcium channel antagonist TTA-A2.

scientific article

De novo Mutations in NALCN Cause a Syndrome of Congenital Contractures of the Limbs and Face with Hypotonia, and Developmental Delay

scholarly preprint article

De novo mutation screening in childhood-onset cerebellar atrophy identifies gain-of-function mutations in the CACNA1G calcium channel gene

scientific article published on 01 July 2018

De novo mutations in NALCN cause a syndrome characterized by congenital contractures of the limbs and face, hypotonia, and developmental delay

scientific article

Dehydroepiandrosterone (DHEA) inhibits voltage-gated T-type calcium channels ⬇️

scientific article published on March 3, 2012

Design of carrier peptide-oligonucleotide conjugates with rapid membrane translocation and nuclear localization properties

scientific article published on 01 February 1998

Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide

scientific article

Endogenous cardiac Ca2+ channels do not overcome the E‐C coupling defect in immortalized dysgenic muscle cells: evidence for a missing link ⬇️

scientific article published on July 24, 1995

Functional expression of CLIFAHDD and IHPRF pathogenic variants of the NALCN channel in neuronal cells reveals both gain- and loss-of-function properties

scientific article published on 13 August 2019

Hallmarks of the channelopathies associated with L-type calcium channels: a focus on the Timothy mutations in Ca(v)1.2 channels.

scientific article published on 31 May 2011

Hypokalemic periodic paralysis: an autosomal dominant muscle disorder caused by mutations in a voltage-gated calcium channel.

scientific article published on June 1997

Inhibition of Cav3.2 T-type Calcium Channels by Its Intracellular I-II Loop.

scientific article published on 30 April 2015

Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons

scientific article published in Scientific Reports

Modulation of T-type Ca2+ channels by Lavender and Rosemary extracts.

scientific article

Modulation of T-type calcium channels by bioactive lipids.

scientific article published on 16 February 2014

Molecular and functional properties of the human alpha(1G) subunit that forms T-type calcium channels.

scientific article

Molecular biology of T-type calcium channels.

scientific article

Molecular genetics of cardiovascular calcium channels

scientific article published on 01 June 1997

Molecular pathways underlying the modulation of T-type calcium channels by neurotransmitters and hormones.

scientific article published on 23 June 2006

Molecular physiology of human cardiovascular ion channels: from electrophysiology to molecular genetics

scientific article published on 01 January 1998

Mouse hippocampal phosphorylation footprint induced by generalized seizures: Focus on ERK, mTORC1 and Akt/GSK-3 pathways.

scientific article published on 3 November 2015

Myogenic tone is impaired at low arterial pressure in mice deficient in the low-voltage-activated CaV 3.1 T-type Ca(2+) channel

scientific article published on 18 February 2013

Neuronal Cav3 channelopathies: recent progress and perspectives

scientific article published on 07 July 2020

Neuronal T-type alpha 1H calcium channels induce neuritogenesis and expression of high-voltage-activated calcium channels in the NG108-15 cell line.

scientific article published on August 2002

Phosphorylation of the Cav3.2 T-type calcium channel directly regulates its gating properties

scientific article

Physiopathology of calcium channels: identification of calcium channelopathies

scientific article published on 01 January 1998

Plasma membrane expression of T-type calcium channel alpha(1) subunits is modulated by high voltage-activated auxiliary subunits.

scientific article published on 27 April 2004

RNAi silencing of P/Q-type calcium channels in Purkinje neurons of adult mouse leads to episodic ataxia type 2.

scientific article published on 21 April 2014

Role of voltage-gated calcium channels in epilepsy.

scientific article

Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability

scientific article

Specific properties of T-type calcium channels generated by the human alpha 1I subunit.

scientific article published in June 2000

Subunit-specific modulation of T-type calcium channels by zinc.

scientific article published on 2 November 2006

T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids.

scientific article published in October 2009

T-type calcium channels are inhibited by fluoxetine and its metabolite norfluoxetine.

scientific article published in March 2006

T-type calcium channels are involved in hypoxic pulmonary hypertension

scientific article published on 11 July 2014

T-type calcium channels in differentiation and proliferation.

scientific article published on 21 June 2006

T-type calcium channels: from discovery to channelopathies, 25 years of research

scientific article published on 10 July 2008

T-type voltage gated calcium channels are involved in endothelium-dependent relaxation of mice pulmonary artery

scientific article published on 21 April 2017

Temperature-dependent modulation of CaV3 T-type calcium channels by protein kinases C and A in mammalian cells.

scientific article published on 12 September 2007

The I-II loop controls plasma membrane expression and gating of Ca(v)3.2 T-type Ca2+ channels: a paradigm for childhood absence epilepsy mutations

scientific article

The NALCN ion channel is a new actor in pancreatic β-cell physiology.

scientific article published on January 2010

The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic beta-cell line

scientific article

The alpha1I T-type calcium channel exhibits faster gating properties when overexpressed in neuroblastoma/glioma NG 108-15 cells.

scientific article published on November 2001

The beta subunit controls the gating and dihydropyridine sensitivity of the skeletal muscle Ca2+ channel ⬇️

scientific article published on November 1, 1992

The involvement of Cav3.2/alpha1H T-type calcium channels in excitability of mouse embryonic primary vestibular neurones.

scientific article published on 16 June 2005

The molecular basis for T-type Ca2+ channel inhibition by G protein beta2gamma2 subunits.

scientific article

The sodium leak channel, NALCN, in health and disease

scientific article

Towards a unified nomenclature describing voltage-gated calcium channel genes

scientific article (publication date: August 1997)

Towards the discovery of novel T-type calcium channel blockers.

scientific article published on May 2007

Transient down-regulation of L-type Ca(2+) channel and dystrophin expression after balloon injury in rat aortic cells

scientific article published on 01 January 2001

[Calcium channelopathies: the current challenges]

scientific article published on 01 December 2006

[Functional specificity of T-type calcium channels and their roles in neuronal differentiation]

scientific article published on 01 January 2003

[Genetic diversity of voltage-gated calcium channels]

scientific article published on 01 May 2004

[Molecular diversity of calcium channel activities by depolarization]

scientific article published on 01 March 2000

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