List of works - M Anthony Moody

A comparison of neonatal Gram-negative rod and Gram-positive cocci meningitis.

scientific article published in February 2006

A rhesus macaque model of Asian-lineage Zika virus infection

scientific article

Aberrant B cell repertoire selection associated with HIV neutralizing antibody breadth

scientific article published on 20 January 2020

Adjuvant-dependent enhancement of HIV Env-specific antibody responses in infant rhesus macaques

article

Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity

scientific article published on 31 August 2016

An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum

scientific article

An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.

scientific article published on 10 March 2014

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

scientific article

Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines

scientific article

Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved

scientific article

Antibody polyspecificity and neutralization of HIV-1: a hypothesis

scientific article

Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses

scientific article

Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family

scientific article

Antigen-specific B cell detection reagents: use and quality control

scientific article

B cell responses to HIV-1 infection and vaccination: pathways to preventing infection

scientific article

Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.

scientific article

Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency

scientific article published on 31 January 2020

Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

scientific article

CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies

scientific article

Capacity for infectious HIV-1 virion capture differs by envelope antibody specificity

scientific article published on 19 February 2014

Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk

scientific article published on 2 March 2016

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

scientific article

Cross-Reactive HIV-1-Neutralizing Human Monoclonal Antibodies Identified from a Patient with 2F5-Like Antibodies

Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies

scientific article

Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells

scientific article

Eliminating antibody polyreactivity through addition of N-linked glycosylation

scientific article published on 12 May 2015

Enhanced antibody responses to an HIV-1 membrane-proximal external region antigen in mice reconstituted with cultured lymphocytes

scientific article published on 03 March 2014

Epitope specificity of human immunodeficiency virus-1 antibody dependent cellular cytotoxicity [ADCC] responses

scientific article published on July 2013

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies

scientific article

Functional interrogation and mining of natively paired human VH:VL antibody repertoires

scientific article published on 8 January 2018

Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region

scientific article

H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination

scientific article (publication date: 2011)

HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces Gp41 Antibody Immunodominance in Rhesus Macaques

scientific article published on 09 August 2017

HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions

scientific article published on 30 January 2020

HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.

scientific article published on 14 November 2016

HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies

scientific article published on 30 July 2015

HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design

scientific article

HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteria

scientific article

HIV-1 envelope induces memory B cell responses that correlate with plasma antibody levels after envelope gp120 protein vaccination or HIV-1 infection

scientific article

HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages

scientific article published on 2 May 2012

HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life.

scientific article published on 9 January 2013

HIV-1 specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galcer Blocking and Phagocytosis

scientific article published on 10 January 2018

HIV-1 specific IgA detected in vaginal secretions of HIV uninfected women participating in a microbicide trial in Southern Africa are primarily directed toward gp120 and gp140 specificities

scientific article

HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities

scientific article

HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers

scientific article published on 15 July 2019

Heterologous protection against Asian Zika virus challenge in rhesus macaques

scientific article

Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection

scientific article

Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements

scientific article

Immune checkpoint modulation enhances HIV-1 antibody induction

scientific article published on 19 February 2020

Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies

scientific article

Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice

scientific article published on 23 December 2016

Immunogenic Stimulus for Germline Precursors of Antibodies that Engage the Influenza Hemagglutinin Receptor-Binding Site.

scientific article

Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies

scientific article

Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies.

scientific article published on January 2017

Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome

scientific article

Implementation of a Pooled Surveillance Testing Program for Asymptomatic SARS-CoV-2 Infections on a College Campus - Duke University, Durham, North Carolina, August 2-October 11, 2020

scientific article published on 20 November 2020

Increased expression of anti-apoptosis genes in peripheral blood cells from patients with paroxysmal nocturnal hemoglobinuria.

scientific article

Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design

scientific article published on 28 May 2008

Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses

scientific article

Infectious virion capture by HIV-1 gp120-specific IgG from RV144 vaccinees

scientific article published on 08 May 2013

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

article

Influence of HLA-C expression level on HIV control

scientific article published on April 2013

Influence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses

scientific article published on 18 January 2017

Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain

scientific article

Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

scientific article

Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations ⬇️

scientific article published on 23 November 2017

Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages

scientific article published on April 2016

Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum

scientific article

Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting

scientific article

Isolation of a monoclonal antibody that targets the alpha-2 helix of gp120 and represents the initial autologous neutralizing-antibody response in an HIV-1 subtype C-infected individual

scientific article

Key mutations stabilize antigen-binding conformation during affinity maturation of a broadly neutralizing influenza antibody lineage

scientific article published on 28 February 2015

Leukopak PBMC sample processing for preparing quality control material to support proficiency testing programs

scientific article published on 10 June 2014

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual

scientific article published on 12 March 2019

Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants

scientific article

Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials

scientific article

Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission

scientific article

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

scientific article published on March 2017

Modulation of HIV-1 immunity by adjuvants

scientific article published on May 2014

Necrotizing fasciitis caused by Haemophilus influenzae type E in a 17-year-old girl with systemic lupus erythematosus

scientific article published on 01 January 2010

Neonatal meningitis: what is the correlation among cerebrospinal fluid cultures, blood cultures, and cerebrospinal fluid parameters?

scientific article published on 01 April 2006

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.

scientific article

Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

scientific article

Polychromatic plots: graphical display of multidimensional data

scientific article

Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection

scientific article

Potent and broad HIV-neutralizing antibodies in memory B cells and plasma

scientific article published on January 2017

Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody

scientific article

Primary infection by a human immunodeficiency virus with atypical coreceptor tropism ⬇️

scientific article published on 10 August 2011

Progress in HIV-1 vaccine development.

scientific article

Rapid diagnostic tests for malaria parasites

scientific article

Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth

scientific article published on 19 November 2020

Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial

scientific article published on 30 June 2020

Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation

scientific article

Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies

scientific article

Simultaneous Detection of Antigen-Specific IgG- and IgM-Secreting Cells with a B Cell Fluorospot Assay

scientific article published on 21 March 2012

Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.

scientific article published on March 2017

Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses

scientific article

Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site

scientific article

Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates

scientific article published on 04 June 2021

Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s

scientific article published on 06 January 2022

T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response

scientific article

The Impact of Poxvirus Vector Priming, Protein Co-Administration, and Vaccine Intervals on HIV gp120 Vaccine-Elicited Antibody Magnitude and Function in Infant Macaques

scientific article

The humoral response to HIV-1: new insights, renewed focus.

scientific article published on October 2010

Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques

scientific article published on 08 December 2016

Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates

scientific article

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

scientific article

Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models

scientific article published in December 2017

Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG.

scientific article published on 9 May 2013

Viral receptor-binding site antibodies with diverse germline origins

scientific article published on 7 May 2015

List of works by M Anthony Moody

A comparison of neonatal Gram-negative rod and Gram-positive cocci meningitis.

A rhesus macaque model of Asian-lineage Zika virus infection

Aberrant B cell repertoire selection associated with HIV neutralizing antibody breadth

Adjuvant-dependent enhancement of HIV Env-specific antibody responses in infant rhesus macaques

Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity

An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum

An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines

Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved

Antibody polyspecificity and neutralization of HIV-1: a hypothesis

Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses

Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family

Antigen-specific B cell detection reagents: use and quality control

B cell responses to HIV-1 infection and vaccination: pathways to preventing infection

Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.

Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency

Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies

Capacity for infectious HIV-1 virion capture differs by envelope antibody specificity

Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

Cross-Reactive HIV-1-Neutralizing Human Monoclonal Antibodies Identified from a Patient with 2F5-Like Antibodies

Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies

Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells

Eliminating antibody polyreactivity through addition of N-linked glycosylation

Enhanced antibody responses to an HIV-1 membrane-proximal external region antigen in mice reconstituted with cultured lymphocytes

Epitope specificity of human immunodeficiency virus-1 antibody dependent cellular cytotoxicity [ADCC] responses

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies

Functional interrogation and mining of natively paired human VH:VL antibody repertoires

Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region

H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination

HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces Gp41 Antibody Immunodominance in Rhesus Macaques

HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions

HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.

HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies

HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design

HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteria

HIV-1 envelope induces memory B cell responses that correlate with plasma antibody levels after envelope gp120 protein vaccination or HIV-1 infection

HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages

HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life.

HIV-1 specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galcer Blocking and Phagocytosis

HIV-1 specific IgA detected in vaginal secretions of HIV uninfected women participating in a microbicide trial in Southern Africa are primarily directed toward gp120 and gp140 specificities

HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities

HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers

Heterologous protection against Asian Zika virus challenge in rhesus macaques

Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection

Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements

Immune checkpoint modulation enhances HIV-1 antibody induction

Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies

Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice

Immunogenic Stimulus for Germline Precursors of Antibodies that Engage the Influenza Hemagglutinin Receptor-Binding Site.

Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies

Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies.

Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome

Implementation of a Pooled Surveillance Testing Program for Asymptomatic SARS-CoV-2 Infections on a College Campus - Duke University, Durham, North Carolina, August 2-October 11, 2020

Increased expression of anti-apoptosis genes in peripheral blood cells from patients with paroxysmal nocturnal hemoglobinuria.

Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design

Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses

Infectious virion capture by HIV-1 gp120-specific IgG from RV144 vaccinees

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

Influence of HLA-C expression level on HIV control

Influence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses

Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain

Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations ⬇️

Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages

Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum

Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting

Isolation of a monoclonal antibody that targets the alpha-2 helix of gp120 and represents the initial autologous neutralizing-antibody response in an HIV-1 subtype C-infected individual

Key mutations stabilize antigen-binding conformation during affinity maturation of a broadly neutralizing influenza antibody lineage

Leukopak PBMC sample processing for preparing quality control material to support proficiency testing programs

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual

Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants

Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials

Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

Modulation of HIV-1 immunity by adjuvants

Necrotizing fasciitis caused by Haemophilus influenzae type E in a 17-year-old girl with systemic lupus erythematosus