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List of works by Dominik J. Schaer

A model to visualize the fate of iron after intracranial hemorrhage using isotopic tracers and elemental bioimaging

A model to visualize the fate of iron after intracranial hemorrhage using isotopic tracers and elemental bioimaging

scientific article published in 2022

Activating transcription factor 1 directs Mhem atheroprotective macrophages through coordinated iron handling and foam cell protection.

scientific article

Assignment of the CD163 antigen (CD163) to mouse chromosome 6 band F2 by radiation hybrid mapping

scientific article published on 01 January 2002

CME-Antworten

CME: Das Schweizer Fallpauschalensystem.

scientific article published in January 2017

Cell-Free Oxyhemoglobin in Cerebrospinal Fluid After Aneurysmal Subarachnoid Hemorrhage: Biomarker and Potential Therapeutic Target

scientific article published on 27 August 2018

Clearance and control mechanisms of hemoglobin from cradle to grave.

scientific article published in February 2010

Clinical outcomes in patients with systemic lupus erythematosus treated with belimumab in clinical practice settings: a retrospective analysis of results from the OBSErve study in Switzerland

scientific article published on 01 February 2019

Comment to: F. M. Nackhoul et al. (2001) Haptoglobin phenotype and diabetic nephropathy. Diabetologia 44: 602-604

scientific article published on 01 November 2001

Depletion of haptoglobin and hemopexin promote hemoglobin-mediated lipoprotein oxidation in sickle cell disease

scientific article published on 26 July 2018

Down selection of polymerized bovine hemoglobins for use as oxygen releasing therapeutics in a guinea pig model

scientific article

Expression and secretion of procalcitonin and calcitonin gene-related peptide by adherent monocytes and by macrophage-activated adipocytes.

scientific article published in August 2004

Expression of CD163 on human histiocytic cells is different in tuberculosis-induced and schistosomiasis-induced granulomas

scientific article published on 14 December 2011

Expression of the hemoglobin scavenger receptor (CD163/HbSR) as immunophenotypic marker of monocytic lineage in acute myeloid leukemia

scientific article published on 01 May 2003

Extracellular Hb enhances cardiac toxicity in endotoxemic guinea pigs: protective role of haptoglobin.

scientific article

Extracellular hemoglobin polarizes the macrophage proteome toward Hb-clearance, enhanced antioxidant capacity and suppressed HLA class 2 expression

scientific article published on 14 April 2011

Functional expression of the CD163 scavenger receptor on acute myeloid leukemia cells of monocytic lineage.

scientific article published on 20 December 2005

Gating the radical hemoglobin to macrophages: the anti-inflammatory role of CD163, a scavenger receptor.

scientific article published on July 2007

Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm

scientific article published on 01 December 2019

Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification

scientific article published on 08 January 2009

Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development

scientific article

Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy.

scientific article published on 26 March 2012

Hemophagocytic syndrome caused by primary herpes simplex virus 1 infection: report of a first case.

scientific article published on 3 July 2010

Human Hp1-1 and Hp2-2 phenotype-specific haptoglobin therapeutics are both effective in vitro and in guinea pigs to attenuate hemoglobin toxicity.

scientific article published on 28 March 2013

Impact of cell-free hemoglobin on contracting skeletal muscle microvascular oxygen pressure dynamics.

scientific article published on 8 March 2018

Induction and antimicrobial activity of platelet basic protein derivatives in human monocytes.

scientific article published on 17 August 2004

Induction of the CD163-dependent haemoglobin uptake by macrophages as a novel anti-inflammatory action of glucocorticoids.

scientific article published in October 2002

Inhibition of meningitis-associated neutrophil apoptosis by TNF-α depends on functional PI3-kinase in monocytes.

scientific article

Iron accelerates hemoglobin oxidation increasing mortality in vascular diseased guinea pigs following transfusion of stored blood.

scientific article

Modeling hemoglobin and hemoglobin:haptoglobin complex clearance in a non-rodent species-pharmacokinetic and therapeutic implications.

scientific article

Not a tropical, but a non the less exotic fever

scientific article published on August 2013

Phenotype-specific recombinant haptoglobin polymers co-expressed with C1r-like protein as optimized hemoglobin-binding therapeutics.

scientific article published on 15 March 2018

Proteinase-activated receptors induce nonoxidative, antimicrobial peptides and increased antimicrobial activity in human mononuclear phagocytes.

scientific article published on 9 November 2006

Quantitative mass spectrometry defines an oxidative hotspot in hemoglobin that is specifically protected by haptoglobin

scientific article published on 01 August 2010

Regulated expression of platelet factor 4 in human monocytes--role of PARs as a quantitatively important monocyte activation pathway

scientific article published on 23 March 2005

Retinal microangiopathy and rapidly fatal cerebral edema in a patient with adult-onset Still's disease and concurrent macrophage activation syndrome.

scientific article

Reversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbbth3/+ (heterozygous B1/B2 globin gene deletion) mice.

scientific article published on 23 January 2015

Sequestration of extracellular hemoglobin within a haptoglobin complex decreases its hypertensive and oxidative effects in dogs and guinea pigs

scientific article

Soluble hemoglobin-haptoglobin scavenger receptor CD163 as a lineage-specific marker in the reactive hemophagocytic syndrome.

scientific article published in January 2005

Spin trapping combined with quantitative mass spectrometry defines free radical redistribution within the oxidized hemoglobin:haptoglobin complex

scientific article published on 28 April 2015

The macrophage hemoglobin scavenger receptor (CD163) as a genetically determined disease modifying pathway in atherosclerosis

scientific article published on 01 July 2002

Transcriptome analysis revealed unique genes as targets for the anti-inflammatory action of activated protein C in human macrophages.

scientific article

[Behçet disease].

scientific article

[CME. Biologics in vasculitis]

scientific article published on 01 January 2015

[Löfgren syndrome - the acute form of sarcoidosis]

scientific article published on 01 November 2014

[Therapy of anaphylaxis]

scientific article published on 01 May 2014

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