List of works - Mads Werner

A capsaicin (8%) patch in the treatment of severe persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled trial

scientific article

A single session of hyperbaric oxygen therapy demonstrates acute and long-lasting neuroplasticity effects in humans: a replicated, randomized controlled clinical trial

scientific article published on 31 July 2019

A systematic review of peri-operative melatonin.

scientific article published on 19 May 2014

Absence of analgesic effect of intravenous melatonin administration during daytime after laparoscopic cholecystectomy: a randomized trial.

scientific article published on 29 October 2014

Analgesic and antihyperalgesic effects of melatonin in a human inflammatory pain model: a randomized, double-blind, placebo-controlled, three-arm crossover study.

scientific article published in November 2015

Analgesic effects of dexamethasone in burn injury

scientific article published on 01 May 2002

Analgesic treatment in laparoscopic gastric bypass surgery: a systematic review of randomized trials.

scientific article published on March 2014

Arthroscopic Knee Surgery Does Not Modify Hyperalgesic Responses to Heat Injury ⬇️

scientific article published on November 1, 2003

Assessment of Postoperative Analgesic Drug Efficacy: Method of Data Analysis Is Critical.

scientific article

Assessment of deep tissue hyperalgesia in the groin - a method comparison of electrical vs. pressure stimulation

scientific article published on 18 July 2014

Aδ and not C fibers mediate thermal hyperalgesia to short laser stimuli after burn injury in man

scientific article published on 01 November 2018

Balanced analgesia: what is it and what are its advantages in postoperative pain?

scientific article

Combining an oral opioid-receptor agonist and the antagonist naloxone: A smart drug design that removes some but not all adverse effects of the opioid analgesic

scientific article published on 01 April 2014

Correction: Secondary Hyperalgesia Phenotypes Exhibit Differences in Brain Activation during Noxious Stimulation

scientific article published on 15 May 2015

Demarcation of secondary hyperalgesia zones: Punctate stimulation pressure matters.

scientific article

Does naloxone reinstate secondary hyperalgesia in humans after resolution of a burn injury? A placebo-controlled, double-blind, randomized, cross-over study

scientific article

Does nerve identification during open inguinal herniorrhaphy reduce the risk of nerve damage and persistent pain?

scientific article published on 11 July 2012

Dysejaculation after laparoscopic inguinal herniorrhaphy: a nationwide questionnaire study

scientific article published on 20 October 2011

E-learning programs in oncology: a nationwide experience from 2005 to 2014.

scientific article

Effect of a high-dose target-controlled naloxone infusion on pain and hyperalgesia in patients following groin hernia repair: study protocol for a randomized controlled trial.

scientific article published on 10 November 2015

Effects of target-controlled infusion of high-dose naloxone on pain and hyperalgesia in a human thermal injury model: a study protocol: A randomized, double-blind, placebo-controlled, crossover trial with an enriched design.

scientific article

Endogenous opioid antagonism in physiological experimental pain models: a systematic review

scientific article

Endoscopic versus open radial artery harvest and mammario-radial versus aorto-radial grafting in patients undergoing coronary artery bypass surgery: protocol for the 2 × 2 factorial designed randomised NEO trial.

scientific article

Erratum to: 'Effect of a high-dose target-controlled naloxone infusion on pain and hyperalgesia in patients following groin hernia repair: study protocol for a randomized controlled trial'.

scientific article published on 20 January 2016

General Anaesthesia With Multimodal Principles Versus Intrathecal Analgesia With Conventional Principles in Total Knee Arthroplasty: A Consecutive, Randomized Study ⬇️

scientific article published on January 11, 2013

Good from far. Far from good.

scientific article published on 24 October 2012

Healthy volunteers can be phenotyped using cutaneous sensitization pain models.

scientific article

High-dose naloxone, an experimental tool uncovering latent sensitisation: pharmacokinetics in humans

scientific article published on 18 January 2019

Humidity affects the performance of von Frey monofilaments.

scientific article published in May 2011

Hyperbaric oxygen therapy attenuates central sensitization induced by a thermal injury in humans.

scientific article published on 3 March 2015

I. Defining persistent post-surgical pain: is an update required?

scientific article published on 18 February 2014

Late sensory changes following chest drain insertion during thoracotomy.

scientific article published on 4 February 2013

Lidocaine patch (5%) in treatment of persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial.

scientific article published in December 2013

Management of persistent postsurgical inguinal pain.

scientific article published on 23 May 2014

Morphine metabolism after major liver surgery

scientific article published on 01 June 2007

Morphine- and buprenorphine-induced analgesia and antihyperalgesia in a human inflammatory pain model: a double-blind, randomized, placebo-controlled, five-arm crossover study

scientific article published on 9 January 2013

Neurophysiological characterization of persistent pain after laparoscopic inguinal hernia repair

scientific article published on 09 April 2011

Pain and sensory dysfunction 6 to 12 months after inguinal herniotomy

scientific article published on 01 July 2004

Pain-related psychological distress, self-rated health and significance of neuropathic pain in Danish soldiers injured in Afghanistan.

scientific article published on 30 June 2015

Persistent pain following groin hernia repair: what is the best practice in pain management?

scientific article published on 01 January 2015

Persistent postsurgical pain: evidence from breast cancer surgery, groin hernia repair, and lung cancer surgery

scientific article published in January 2014

Pharmacokinetic-Pharmacodynamic Modelling of the Analgesic and Antihyperalgesic Effects of Morphine after Intravenous Infusion in Human Volunteers

scientific article published on 17 March 2014

Pharmacokinetics of high-dose intravenous melatonin in humans

scientific article published on 14 September 2015

Pharmacokinetics of oral and intravenous melatonin in healthy volunteers

scientific article published on 19 February 2016

Post-operative pain treatment in Denmark from 2000 to 2009: a nationwide sequential survey on organizational aspects.

scientific article published on 5 March 2012

Prediction of postoperative pain: a systematic review of predictive experimental pain studies.

scientific article published on June 2010

Quantitative Sensory Testing in Patients With Postthoracotomy Pain Syndrome

scientific article published on 01 September 2013

Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy.

scientific article published on 5 October 2011

Referred pain and cutaneous responses from deep tissue electrical pain stimulation in the groin.

scientific article published on 12 June 2015

Sample size and effect size calculations are necessary in clinical studies in order to avoid false positive and false negative conclusions

scientific article published on 01 July 2013

Secondary hyperalgesia phenotypes exhibit differences in brain activation during noxious stimulation

scientific article

Sensory testing in patients with postthoracotomy pain syndrome: Part 1: mirror-image sensory dysfunction.

scientific article published in September 2013

Simultaneous quantification of high-dose naloxone and naloxone-3-β-d-glucuronide in human plasma by UHPLC-MS/MS

scientific article published on 21 January 2019

Spatial summation of thermal stimuli assessed by a standardized, randomized, single-blinded technique

scientific article published on 01 October 2015

Tachyphylaxis to local anaesthetics. What is the clinical evidence? A systematic review.

scientific article published on 10 September 2015

Test-retest studies in quantitative sensory testing: a critical review ⬇️

scientific article published on 04 July 2013

The Brief Pain Inventory (BPI) - Revisited and rejuvenated?

scientific article published on 6 May 2016

The acceleration transducer - an assessment of its precision in comparison with a force displacement transducer ⬇️

scientific article published on April 1, 1988

The relationship between chronic pain and cardiovascular disease: Squaring the circle?

scientific article published on 20 September 2016

The role of peripheral afferents in persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial of ultrasound-guided tender point blockade.

scientific article published on June 2016

Trajectories in severe persistent pain after groin hernia repair: a retrospective analysis

scientific article published on 09 October 2020

Trismus-An important issue in pain and palliative care

scientific article published on 01 April 2010

Ultrasound-guided ilioinguinal/iliohypogastric nerve blocks for persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial.

scientific article

Vanguard research in opioid-induced hyperalgesia - but guard the basics.

scientific article published on 3 March 2012

List of works by Mads Werner

A capsaicin (8%) patch in the treatment of severe persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled trial

A single session of hyperbaric oxygen therapy demonstrates acute and long-lasting neuroplasticity effects in humans: a replicated, randomized controlled clinical trial

A systematic review of peri-operative melatonin.

Absence of analgesic effect of intravenous melatonin administration during daytime after laparoscopic cholecystectomy: a randomized trial.

Analgesic and antihyperalgesic effects of melatonin in a human inflammatory pain model: a randomized, double-blind, placebo-controlled, three-arm crossover study.

Analgesic effects of dexamethasone in burn injury

Analgesic treatment in laparoscopic gastric bypass surgery: a systematic review of randomized trials.

Arthroscopic Knee Surgery Does Not Modify Hyperalgesic Responses to Heat Injury ⬇️

Assessment of Postoperative Analgesic Drug Efficacy: Method of Data Analysis Is Critical.

Assessment of deep tissue hyperalgesia in the groin - a method comparison of electrical vs. pressure stimulation

Aδ and not C fibers mediate thermal hyperalgesia to short laser stimuli after burn injury in man

Balanced analgesia: what is it and what are its advantages in postoperative pain?

Combining an oral opioid-receptor agonist and the antagonist naloxone: A smart drug design that removes some but not all adverse effects of the opioid analgesic

Correction: Secondary Hyperalgesia Phenotypes Exhibit Differences in Brain Activation during Noxious Stimulation

Demarcation of secondary hyperalgesia zones: Punctate stimulation pressure matters.

Does naloxone reinstate secondary hyperalgesia in humans after resolution of a burn injury? A placebo-controlled, double-blind, randomized, cross-over study

Does nerve identification during open inguinal herniorrhaphy reduce the risk of nerve damage and persistent pain?

Dysejaculation after laparoscopic inguinal herniorrhaphy: a nationwide questionnaire study

E-learning programs in oncology: a nationwide experience from 2005 to 2014.

Effect of a high-dose target-controlled naloxone infusion on pain and hyperalgesia in patients following groin hernia repair: study protocol for a randomized controlled trial.

Effects of target-controlled infusion of high-dose naloxone on pain and hyperalgesia in a human thermal injury model: a study protocol: A randomized, double-blind, placebo-controlled, crossover trial with an enriched design.

Endogenous opioid antagonism in physiological experimental pain models: a systematic review

Endoscopic versus open radial artery harvest and mammario-radial versus aorto-radial grafting in patients undergoing coronary artery bypass surgery: protocol for the 2 × 2 factorial designed randomised NEO trial.

Erratum to: 'Effect of a high-dose target-controlled naloxone infusion on pain and hyperalgesia in patients following groin hernia repair: study protocol for a randomized controlled trial'.

General Anaesthesia With Multimodal Principles Versus Intrathecal Analgesia With Conventional Principles in Total Knee Arthroplasty: A Consecutive, Randomized Study ⬇️

Good from far. Far from good.

Healthy volunteers can be phenotyped using cutaneous sensitization pain models.

High-dose naloxone, an experimental tool uncovering latent sensitisation: pharmacokinetics in humans

Humidity affects the performance of von Frey monofilaments.

Hyperbaric oxygen therapy attenuates central sensitization induced by a thermal injury in humans.

I. Defining persistent post-surgical pain: is an update required?

Late sensory changes following chest drain insertion during thoracotomy.

Lidocaine patch (5%) in treatment of persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial.

Management of persistent postsurgical inguinal pain.

Morphine metabolism after major liver surgery

Morphine- and buprenorphine-induced analgesia and antihyperalgesia in a human inflammatory pain model: a double-blind, randomized, placebo-controlled, five-arm crossover study

Neurophysiological characterization of persistent pain after laparoscopic inguinal hernia repair

Pain and sensory dysfunction 6 to 12 months after inguinal herniotomy

Pain-related psychological distress, self-rated health and significance of neuropathic pain in Danish soldiers injured in Afghanistan.

Persistent pain following groin hernia repair: what is the best practice in pain management?

Persistent postsurgical pain: evidence from breast cancer surgery, groin hernia repair, and lung cancer surgery

Pharmacokinetic-Pharmacodynamic Modelling of the Analgesic and Antihyperalgesic Effects of Morphine after Intravenous Infusion in Human Volunteers

Pharmacokinetics of high-dose intravenous melatonin in humans

Pharmacokinetics of oral and intravenous melatonin in healthy volunteers

Post-operative pain treatment in Denmark from 2000 to 2009: a nationwide sequential survey on organizational aspects.

Prediction of postoperative pain: a systematic review of predictive experimental pain studies.

Quantitative Sensory Testing in Patients With Postthoracotomy Pain Syndrome

Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy.

Referred pain and cutaneous responses from deep tissue electrical pain stimulation in the groin.

Sample size and effect size calculations are necessary in clinical studies in order to avoid false positive and false negative conclusions

Secondary hyperalgesia phenotypes exhibit differences in brain activation during noxious stimulation

Sensory testing in patients with postthoracotomy pain syndrome: Part 1: mirror-image sensory dysfunction.

Simultaneous quantification of high-dose naloxone and naloxone-3-β-d-glucuronide in human plasma by UHPLC-MS/MS

Spatial summation of thermal stimuli assessed by a standardized, randomized, single-blinded technique

Tachyphylaxis to local anaesthetics. What is the clinical evidence? A systematic review.

Test-retest studies in quantitative sensory testing: a critical review ⬇️

The Brief Pain Inventory (BPI) - Revisited and rejuvenated?

The acceleration transducer - an assessment of its precision in comparison with a force displacement transducer ⬇️

The relationship between chronic pain and cardiovascular disease: Squaring the circle?

The role of peripheral afferents in persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial of ultrasound-guided tender point blockade.

Trajectories in severe persistent pain after groin hernia repair: a retrospective analysis

Trismus-An important issue in pain and palliative care

Ultrasound-guided ilioinguinal/iliohypogastric nerve blocks for persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial.

Vanguard research in opioid-induced hyperalgesia - but guard the basics.