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List of works by Thomas Rutkowski

2-Deoxyglucose-induced toxicity is regulated by Bcl-2 family members and is enhanced by antagonizing Bcl-2 in lymphoma cell lines ⬇️

scientific article published on October 10, 2011

A data-entrained computational model for testing the regulatory logic of the vertebrate unfolded protein response.

scientific article published on 18 April 2018

A gluconeogenic tryst in the nucleus, with ER stress as the third wheel.

scientific article published on 10 November 2009

A trip to the ER: coping with stress

scientific article (publication date: 2004)

Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro‐survival signalling as part of the mucosal inflammatory response ⬇️

scientific article published on September 1, 2013

All roads lead to ATF4

scientific article

Brain endoplasmic reticulum stress mechanistically distinguishes the saline-intake and hypertensive response to deoxycorticosterone acetate-salt

scientific article published on 20 April 2015

C/EBP Homologous Protein (CHOP) Contributes to Suppression of Metabolic Genes during Endoplasmic Reticulum Stress in the Liver ⬇️

scientific article published on December 31, 2012

Conformational control through translocational regulation: a new view of secretory and membrane protein folding.

scientific article

ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis.

scientific article published in May 2017

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

scientific article

Endoplasmic reticulum stress impairs IL-4/IL-13 signaling through C/EBPβ-mediated transcriptional suppression ⬇️

scientific article published on June 26, 2013

Experimental reconstitution of chronic ER stress in the liver reveals feedback suppression of BiP mRNA expression

scientific article (publication date: 10 December 2016)

Heightened Induction of Proapoptotic Signals in Response to Endoplasmic Reticulum Stress in Primary Fibroblasts from a Mouse Model of Longevity ⬇️

scientific article published on July 12, 2011

Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway.

scientific article published on 22 December 2011

Inhibition of fatty acid oxidation enhances oxidative protein folding and protects hepatocytes from endoplasmic reticulum stress ⬇️

scientific article published on January 19, 2012

Inositol-requiring enzyme 1 inhibits respiratory syncytial virus replication

scientific article published on 04 February 2014

Lipase maturation factor 1 (lmf1) is induced by endoplasmic reticulum stress through activating transcription factor 6α (Atf6α) signaling.

scientific article

Liver function and dysfunction - a unique window into the physiological reach of ER stress and the unfolded protein response

scientific article published on 23 January 2018

Long-term correction of hemophilia A mice following lentiviral mediated delivery of an optimized canine factor VIII gene.

scientific article published on 14 September 2017

Regulation of basal cellular physiology by the homeostatic unfolded protein response

scientific article

Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences.

scientific article published on 02 December 2013

Signal sequences initiate the pathway of maturation in the endoplasmic reticulum lumen.

scientific article published on 27 May 2003

Synthetic embryonic lethality upon deletion of the ER cochaperone p58(IPK) and the ER stress sensor ATF6α

scientific article

That which does not kill me makes me stronger: adapting to chronic ER stress

scientific article published on 01 October 2007

The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis

scientific article (publication date: 2013)

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

scientific article published on December 2008

piggyBac-mediated phenotypic correction of factor VIII deficiency

scientific article

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