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List of works by Lukáš Trantírek

A cost-effective amino-acid-type selective isotope labeling of proteins expressed in Leishmania tarentolae.

scientific article published in June 2009

A-like guanine-guanine stacking in the aqueous DNA duplex of d(GGGGCCCC).

scientific article

Advances in the cellular structural biology of nucleic acids.

scientific article published on 21 April 2018

An A-type double helix of DNA having B-type puckering of the deoxyribose rings.

scientific article

An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.

scientific article published on 27 July 2016

Analysis of binding interfaces of the human scaffold protein AXIN1 by peptide microarrays

scientific article published on 30 August 2018

Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.

scientific article

Clustered abasic lesions profoundly change the structure and stability of human telomeric G-quadruplexes.

scientific article published on 22 March 2017

Crystal structures of T. brucei MRP1/MRP2 guide-RNA binding complex reveal RNA matchmaking mechanism

scientific article published on 01 August 2006

Determination of the glycosidic torsion angles in uniformly 13C-labeled nucleic acids from vicinal coupling constants 3J(C2)/4-H1' and 3J(C6)/8-H1'.

scientific article published in May 2002

Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1

scientific article published on 18 April 2019

Diverse effects of naturally occurring base lesions on the structure and stability of the human telomere DNA quadruplex.

scientific article published on 15 July 2015

Evaluating the Effects of the Nonplanarity of Nucleic Acid Bases on NMR, IR, and Vibrational Circular Dichroism Spectra: A Density Functional Theory Computational Study ⬇️

scientific article published on September 23, 2010

Evaluation of parameters critical for observing nucleic acids inside living Xenopus laevis oocytes by in-cell NMR spectroscopy.

scientific article published in November 2009

Evaluation of stability of DNA i-motifs in the nuclei of living mammalian cells.

scientific article published on 20 December 2017

Expression of FGF19 in human embryonic stem cells.

scientific article

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase

scientific article published on 19 February 2019

Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5.

scientific article

G-quadruplex formation in the Oct4 promoter positively regulates Oct4 expression.

scientific article published on 15 November 2016

Guanine bases in DNA G-quadruplex adopt nonplanar geometries owing to solvation and base pairing.

scientific article

Impact of nucleic acid self-alignment in a strong magnetic field on the interpretation of indirect spin-spin interactions.

scientific article published on 19 December 2015

In-Cell NMR Spectroscopy of Nucleic Acids in Human Cells

scientific article published on 29 November 2018

In-cell NMR and EPR spectroscopy of biomacromolecules

scientific article

Indirect NMR Spin−Spin Coupling Constants3J(P,C) and2J(P,H) across the P−O···H−C Link Can Be Used for Structure Determination of Nucleic Acids

scientific article published in May 2006

Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480.

scientific article published on 27 November 2017

Instability restricts signaling of multiple fibroblast growth factors.

scientific article

Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses.

scientific article published on 13 January 2017

Metabolic stress regulates ERK activity by controlling KSR-RAF heterodimerization

scientific article published on 20 December 2017

Microenvironmental interactions between endothelial and lymphoma cells: a role for the canonical WNT pathway in Hodgkin lymphoma.

scientific article published on 18 August 2016

Monitoring DNA-Ligand Interactions in Living Human Cells Using NMR Spectroscopy

scientific article published on 14 August 2019

NF449 is a novel inhibitor of fibroblast growth factor receptor 3 (FGFR3) signaling active in chondrocytes and multiple myeloma cells

scientific article

NMR (13)C-relaxation study of base and sugar dynamics in GCAA RNA hairpin tetraloop.

scientific article published in December 2007

NMR Cross-Correlated Relaxation Rates Reveal Ion Coordination Sites in DNA

scientific article published on 7 September 2011

Nanodiamonds as “artificial proteins”: Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals

scientific article published on 21 May 2018

Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle.

scientific article

One reporter for in-cell activity profiling of majority of protein kinase oncogenes.

scientific article published on 15 February 2017

Pyramidalization of the glycosidic nitrogen provides the way for efficient cleavage of the N-glycosidic bond of 8-OxoG with the hOGG1 DNA repair protein

scientific article published on 09 October 2012

Reaction mechanism and stereochemistry of gamma-hexachlorocyclohexane dehydrochlorinase LinA.

scientific article

Revisiting the planarity of nucleic acid bases: Pyramidilization at glycosidic nitrogen in purine bases is modulated by orientation of glycosidic torsion.

scientific article published on November 2009

Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.

scientific article

Solution structures of stem-loop RNAs that bind to the two N-terminal RNA-binding domains of nucleolin

scientific article

Structure and function of the native and recombinant mitochondrial MRP1/MRP2 complex from Trypanosoma brucei

scientific article published on 26 January 2008

Structure of a Stable G-Hairpin.

scientific article published on 20 February 2017

Sugar pucker modulates the cross-correlated relaxation rates across the glycosidic bond in DNA.

scientific article published in October 2005

The PTH/PTHrP-SIK3 pathway affects skeletogenesis through altered mTOR signaling

scientific article published on 01 September 2018

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

scientific article published on 18 September 2018

The parallel G-quadruplex structure of vertebrate telomeric repeat sequences is not the preferred folding topology under physiological conditions.

scientific article published on 30 March 2011

Unique C. elegans telomeric overhang structures reveal the evolutionarily conserved properties of telomeric DNA

scientific article published on 8 April 2015

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