List of works by Richard D. Leapman

A structural framework for a near-minimal form of life: mass and compositional analysis of the helical mollicute Spiroplasma melliferum BC3.

scientific article

Aggregation and fibril morphology of the Arctic mutation of Alzheimer's Aβ peptide by CD, TEM, STEM and in situ AFM

scientific article

Application of EELS and EFTEM to the life sciences enabled by the contributions of Ondrej Krivanek

scientific article published on 01 March 2017

Biodegradable gold nanovesicles with an ultrastrong plasmonic coupling effect for photoacoustic imaging and photothermal therapy

scientific article

Biointeractions of ultrasmall glutathione-coated gold nanoparticles: effect of small size variations

scientific article published on 3 March 2016

Chimeric ferritin nanocages for multiple function loading and multimodal imaging

scientific article

Combining portable Raman probes with nanotubes for theranostic applications

scientific article

Cryo-electron tomography of the magnetotactic vibrio Magnetovibrio blakemorei: insights into the biomineralization of prismatic magnetosomes.

scientific article

DNA-inorganic hybrid nanovaccine for cancer immunotherapy

scientific article published on 7 March 2016

Deletion of Ia-2 and/or Ia-2β in mice decreases insulin secretion by reducing the number of dense core vesicles

scientific journal article

Determining molecular mass distributions and compositions of functionalized dendrimer nanoparticles.

scientific article published on June 2009

Development and application of STEM for the biological sciences

scientific article

Development of Electron Energy Loss Spectroscopy in the Biological Sciences

scientific article

Direct visualization of CaMKII at postsynaptic densities by electron microscopy tomography.

scientific article published in December 2012

Dual-axis electron tomography of biological specimens: Extending the limits of specimen thickness with bright-field STEM imaging.

scientific article

EELS characterization of radiolytic products in frozen samples ⬇️

scientific article published on November 3, 2010

Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells

scientific article published on 18 December 2008

Elemental imaging by EELS and EDXS in the analytical electron microscope : Its relevance to trace element research.

scientific article

Elemental mapping by electron energy loss spectroscopy in biology.

scientific article published in January 2013

Golgi proteins in circulating human platelets are distributed across non-stacked, scattered structures.

scientific article published on 18 October 2016

Identifying individual scaffolding molecules in the postsynaptic density.

scientific article published on August 2008

Imaging the distribution of individual platinum-based anticancer drug molecules attached to single-wall carbon nanotubes

scientific article published on October 2009

In situ compositional analysis of acidocalcisomes in Trypanosoma cruzi

scientific article published on 01 October 1997

Influence of melanosome dynamics on melanoma drug sensitivity.

scientific article published on 24 August 2009

Layer-specific variation of iron content in cerebral cortex as a source of MRI contrast.

scientific article

Limitations of beam damage in electron spectroscopic tomography of embedded cells.

scientific article

Localizing specific elements bound to macromolecules by EFTEM

scientific article published on 01 January 2007

Manipulating the power of an additional phase: a flower-like Au-Fe3O4 optical nanosensor for imaging protease expressions in vivo

scientific article

Mapping protein expression in mouse pancreatic islets by immunolabeling and electron energy loss spectrum-imaging

scientific article published in August 2003

Mass distribution and spatial organization of the linear bacterial motor of Spiroplasma citri R8A2.

scientific article

Mass of the postsynaptic density and enumeration of three key molecules

scientific article

Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas

scholarly article

Monte Carlo electron-trajectory simulations in bright-field and dark-field STEM: implications for tomography of thick biological sections.

scientific article

Multiple modes of calcium-induced calcium release in sympathetic neurons II: a [Ca2+](i)- and location-dependent transition from endoplasmic reticulum Ca accumulation to net Ca release.

scientific article

Nanoparticles: Dissected with electrons

scientific article published on 01 July 2010

Nanoscale 3D cellular imaging by axial scanning transmission electron tomography

scientific article published on 30 August 2009

Nuclear mapping of nanodrug delivery systems in dynamic cellular environments

scientific article

On the feasibility of visualizing ultrasmall gold labels in biological specimens by STEM tomography.

scientific article published on 28 June 2007

Organization of designed nanofibrils assembled from alpha-helical peptides as determined by electron microscopy.

scientific article

Organization of the core structure of the postsynaptic density

scientific article

Phosphorylation and subunit organization of axonal neurofilaments determined by scanning transmission electron microscopy

scientific article

Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors

scientific article

Protein oxidation implicated as the primary determinant of bacterial radioresistance

scientific article

Quantification and thickness correction of EFTEM phosphorus maps.

scientific article

Quantitative EFTEM mapping of near physiological calcium concentrations in biological specimens.

scientific article

Quantitative STEM mass measurement of biological macromolecules in a 300 kV TEM.

scientific article

Quantitative method for estimating stain density in electron microscopy of conventionally prepared biological specimens

scientific article published on 20 February 2020

RESP18, a homolog of the luminal domain IA-2, is found in dense core vesicles in pancreatic islet cells and is induced by high glucose.

scientific article

Reprint of "On the feasibility of visualizing ultrasmall gold labels in biological specimens by STEM tomography" [J. Struct. Biol. 159 (2007) 507-522]

scientific article published on 01 March 2008

Reprint of "Three-dimensional elemental mapping of phosphorus by quantitative electron spectroscopic tomography (QuEST)" [J. Struct. Biol. 160 (2007) 35-48].

scientific article

SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets

scientific article published on 01 November 2018

Self-organized Mn(2+)-Block Copolymer Complexes and Their Use for In Vivo MR Imaging of Biological Processes.

scientific article

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

scientific article

Spatial distributions of sulfur-rich proteins in cornifying epithelia.

scientific article published in November 1997

Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery.

scientific article

Targeted therapeutic nanotubes influence the viscoelasticity of cancer cells to overcome drug resistance

scientific article

Thickness measurement of hydrated and dehydrated cryosections by EELS

scientific article published on 01 February 1996

Three-dimensional distributions of elements in biological samples by energy-filtered electron tomography.

scientific article

Tri-stimuli-responsive biodegradable theranostics for mild hyperthermia enhanced chemotherapy

scientific article

Variations in Glycogen Synthesis in Human Pluripotent Stem Cells with Altered Pluripotent States

scientific article

Water distributions of hydrated biological specimens by valence electron energy loss spectroscopy

scientific article published on 01 July 1993

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