List of works - Edmond J Remarque

A diversity-covering approach to immunization with Plasmodium falciparum apical membrane antigen 1 induces broader allelic recognition and growth inhibition responses in rabbits

scientific article published on 31 March 2008

A malaria vaccine based on the polymorphic block 2 region of MSP-1 that elicits a broad serotype-spanning immune response

scientific article

Acquisition of natural humoral immunity to P. falciparum in early life in Benin: impact of clinical, environmental and host factors

scientific article published on 27 September 2016

Apical membrane antigen 1: a malaria vaccine candidate in review

scientific article published on 15 January 2008

Comparative testing of six antigen-based malaria vaccine candidates directed toward merozoite-stage Plasmodium falciparum

scientific article published on 11 June 2008

Correlation between Virus Replication and Antibody Responses in Macaques following Infection with Pandemic Influenza A Virus.

scientific article

Crystal structure of the malaria vaccine candidate apical membrane antigen 1.

scientific article published on 24 February 2005

Development and evaluation of a multiplex screening assay for Plasmodium falciparum exposure

scientific article published on 23 July 2012

Diversity covering AMA1-MSP119 fusion proteins as malaria vaccines

scientific article published on 19 February 2013

Enhancing blood-stage malaria subunit vaccine immunogenicity in rhesus macaques by combining adenovirus, poxvirus, and protein-in-adjuvant vaccines

scientific article published on 22 November 2010

Generation of humoral immune responses to multi-allele PfAMA1 vaccines; effect of adjuvant and number of component alleles on the breadth of response

scientific article (publication date: 3 November 2010)

Humoral immune response to mixed PfAMA1 alleles; multivalent PfAMA1 vaccines induce broad specificity

scientific article

Humoral immune responses to a single allele PfAMA1 vaccine in healthy malaria-naïve adults

scientific article (publication date: 2012)

Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein

scientific article

Immunization with different PfAMA1 alleles in sequence induces clonal imprint humoral responses that are similar to responses induced by the same alleles as a vaccine cocktail in rabbits

scientific article (publication date: 14 February 2011)

Influenza virosomes: a flu jab for malaria?

scientific article published on 5 August 2008

Interplay between AMA1 immunisation and parasite challenge leads to protection against malaria infection in rhesus macaques

scientific article published on 20 October 2010

KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro

scientific article published on 23 December 2013

Low levels of polymorphisms and no evidence for diversifying selection on the Plasmodium knowlesi Apical Membrane Antigen 1 gene

scientific article published on 16 April 2015

MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques

scientific article

Malaria infection by sporozoite challenge induces high functional antibody titres against blood stage antigens after a DNA prime, poxvirus boost vaccination strategy in Rhesus macaques

scientific article

Malaria vaccine-related benefits of a single protein comprising Plasmodium falciparum apical membrane antigen 1 domains I and II fused to a modified form of the 19-kilodalton C-terminal fragment of merozoite surface protein 1

scientific article

Measurement of the plasma levels of antibodies against the polymorphic vaccine candidate apical membrane antigen 1 in a malaria-exposed population.

scientific article (publication date: 2 February 2012)

Pandemic Swine-Origin H1N1 Influenza Virus Replicates to Higher Levels and Induces More Fever and Acute Inflammatory Cytokines in Cynomolgus versus Rhesus Monkeys and Can Replicate in Common Marmosets.

scientific article

Phase 1 randomized controlled trial to evaluate the safety and immunogenicity of recombinant Pichia pastoris-expressed Plasmodium falciparum apical membrane antigen 1 (PfAMA1-FVO [25-545]) in healthy Malian adults in Bandiagara

scientific article published on 30 August 2016

Plasmodium falciparum 19-kilodalton merozoite surface protein 1 (MSP1)-specific antibodies that interfere with parasite growth in vitro can inhibit MSP1 processing, merozoite invasion, and intracellular parasite development ⬇️

scientific article published on 27 December 2011

Production, Quality Control, Stability and Pharmacotoxicity of a Malaria Vaccine Comprising Three Highly Similar PfAMA1 Protein Molecules to Overcome Antigenic Variation

scientific article

Production, quality control, stability and pharmacotoxicity of cGMP-produced Plasmodium falciparum AMA1 FVO strain ectodomain expressed in Pichia pastoris

scientific article published on 17 September 2008

Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity

scientific article published on 18 April 2013

Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo

scientific article published on 19 December 2011

Safety and immunogenicity of multi-antigen AMA1-based vaccines formulated with CoVaccine HTTM and Montanide ISA 51 in rhesus macaques

scientific article (publication date: 4 July 2011)

Statistical model to evaluate in vivo activities of antimalarial drugs in a Plasmodium cynomolgi-macaque model for Plasmodium vivax malaria

scientific article

Structural comparison of apical membrane antigen 1 orthologues and paralogues in apicomplexan parasites

scientific article published in 2005

Suppression of Plasmodium cynomolgi in rhesus macaques by coinfection with Babesia microti

scientific article

The impact of hotspot-targeted interventions on malaria transmission: study protocol for a cluster-randomized controlled trial

scientific article published on 2 February 2013

The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malaria

scientific article

Towards validated assays for key immunological outcomes in malaria vaccine development

scientific article published on 4 February 2011

Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1

scientific article (publication date: 2011)

Vaccination with Plasmodium knowlesi AMA1 formulated in the novel adjuvant co-vaccine HT™ protects against blood-stage challenge in rhesus macaques

scientific article (publication date: 2011)

List of works by Edmond J Remarque

A diversity-covering approach to immunization with Plasmodium falciparum apical membrane antigen 1 induces broader allelic recognition and growth inhibition responses in rabbits

A malaria vaccine based on the polymorphic block 2 region of MSP-1 that elicits a broad serotype-spanning immune response

Acquisition of natural humoral immunity to P. falciparum in early life in Benin: impact of clinical, environmental and host factors

Apical membrane antigen 1: a malaria vaccine candidate in review

Comparative testing of six antigen-based malaria vaccine candidates directed toward merozoite-stage Plasmodium falciparum

Correlation between Virus Replication and Antibody Responses in Macaques following Infection with Pandemic Influenza A Virus.

Crystal structure of the malaria vaccine candidate apical membrane antigen 1.

Development and evaluation of a multiplex screening assay for Plasmodium falciparum exposure

Diversity covering AMA1-MSP119 fusion proteins as malaria vaccines

Enhancing blood-stage malaria subunit vaccine immunogenicity in rhesus macaques by combining adenovirus, poxvirus, and protein-in-adjuvant vaccines

Generation of humoral immune responses to multi-allele PfAMA1 vaccines; effect of adjuvant and number of component alleles on the breadth of response

Humoral immune response to mixed PfAMA1 alleles; multivalent PfAMA1 vaccines induce broad specificity

Humoral immune responses to a single allele PfAMA1 vaccine in healthy malaria-naïve adults

Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein

Immunization with different PfAMA1 alleles in sequence induces clonal imprint humoral responses that are similar to responses induced by the same alleles as a vaccine cocktail in rabbits

Influenza virosomes: a flu jab for malaria?

Interplay between AMA1 immunisation and parasite challenge leads to protection against malaria infection in rhesus macaques

KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro

Low levels of polymorphisms and no evidence for diversifying selection on the Plasmodium knowlesi Apical Membrane Antigen 1 gene

MVA.85A boosting of BCG and an attenuated, phoP deficient M. tuberculosis vaccine both show protective efficacy against tuberculosis in rhesus macaques

Malaria infection by sporozoite challenge induces high functional antibody titres against blood stage antigens after a DNA prime, poxvirus boost vaccination strategy in Rhesus macaques

Malaria vaccine-related benefits of a single protein comprising Plasmodium falciparum apical membrane antigen 1 domains I and II fused to a modified form of the 19-kilodalton C-terminal fragment of merozoite surface protein 1

Measurement of the plasma levels of antibodies against the polymorphic vaccine candidate apical membrane antigen 1 in a malaria-exposed population.

Pandemic Swine-Origin H1N1 Influenza Virus Replicates to Higher Levels and Induces More Fever and Acute Inflammatory Cytokines in Cynomolgus versus Rhesus Monkeys and Can Replicate in Common Marmosets.

Phase 1 randomized controlled trial to evaluate the safety and immunogenicity of recombinant Pichia pastoris-expressed Plasmodium falciparum apical membrane antigen 1 (PfAMA1-FVO [25-545]) in healthy Malian adults in Bandiagara

Plasmodium falciparum 19-kilodalton merozoite surface protein 1 (MSP1)-specific antibodies that interfere with parasite growth in vitro can inhibit MSP1 processing, merozoite invasion, and intracellular parasite development ⬇️

Production, Quality Control, Stability and Pharmacotoxicity of a Malaria Vaccine Comprising Three Highly Similar PfAMA1 Protein Molecules to Overcome Antigenic Variation

Production, quality control, stability and pharmacotoxicity of cGMP-produced Plasmodium falciparum AMA1 FVO strain ectodomain expressed in Pichia pastoris

Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity

Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo

Safety and immunogenicity of multi-antigen AMA1-based vaccines formulated with CoVaccine HTTM and Montanide ISA 51 in rhesus macaques

Statistical model to evaluate in vivo activities of antimalarial drugs in a Plasmodium cynomolgi-macaque model for Plasmodium vivax malaria

Structural comparison of apical membrane antigen 1 orthologues and paralogues in apicomplexan parasites

Suppression of Plasmodium cynomolgi in rhesus macaques by coinfection with Babesia microti

The impact of hotspot-targeted interventions on malaria transmission: study protocol for a cluster-randomized controlled trial

The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malaria

Towards validated assays for key immunological outcomes in malaria vaccine development

Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1

Vaccination with Plasmodium knowlesi AMA1 formulated in the novel adjuvant co-vaccine HT™ protects against blood-stage challenge in rhesus macaques

Variations in the quality of malaria-specific antibodies with transmission intensity in a seasonal malaria transmission area of Northern Ghana

Workshop report: Experimental animal models for universal influenza vaccines

Workshop report: Immunoassay standardisation for "universal" influenza vaccines