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List of works by Yoichi Ishitsuka

A selective thromboxane A2 (TXA2) synthase inhibitor, ozagrel, attenuates lung injury and decreases monocyte chemoattractant protein-1 and interleukin-8 mRNA expression in oleic acid-induced lung injury in guinea pigs.

scientific article published on 26 September 2009

Aminophylline, administered at usual doses for rodents in pharmacological studies, induces hippocampal neuronal cell injury under low tidal volume hypoxic conditions in guinea-pigs ⬇️

scientific article published on July 29, 2012

An enzyme combination assay for serum sphingomyelin: Improved specificity through avoiding the interference with lysophosphatidylcholine

scientific article published on 11 January 2016

Anti-inflammatory Effects of Novel Polysaccharide Sacran Extracted from Cyanobacterium Aphanothece sacrum in Various Inflammatory Animal Models.

scientific article published on 10 May 2016

Awareness and current implementation of drug dosage adjustment by pharmacists in patients with chronic kidney disease in Japan: a web-based survey.

scientific article

Cholesterol lowering effects of mono-lactose-appended β-cyclodextrin in Niemann-Pick type C disease-like HepG2 cells

scientific article published on 3 November 2015

Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells.

scientific article published on 6 September 2016

Comparative Study of Constipation Exacerbation by Potassium Binders Using a Loperamide-Induced Constipation Model

scientific article published on 03 April 2020

Comparative effects of respiratory stimulants on hypoxic neuronal cell injury in SH-SY5Y cells and in hippocampal slice cultures from rat pups

scientific article published on 01 June 2013

Corrigendum to "In vitro evaluation of 2-hydroxyalkylated β-cyclodextrins as potential therapeutic agents for Niemann-pick type C disease" [Mol. Genet. Metab. (2016) 214-219].

scientific article

Differences in reaction specificity toward lipoprotein X and abnormal LDL among 6 homogeneous assays for LDL-cholesterol

scientific article published on 05 October 2014

Differential Effects of 2-Hydroxypropyl-Cyclodextrins on Lipid Accumulation in Npc1-Null Cells

scientific article published on 30 January 2020

Edoxaban Exerts Antioxidant Effects Through FXa Inhibition and Direct Radical-Scavenging Activity ⬇️

scientific article published on 24 August 2019

Effect of acetaminophen on the progression of renal damage in adenine induced renal failure model rats

scientific article published on 12 October 2012

Effects of bolus injection of soybean-based fat emulsion and fatty acids on pulmonary gas exchange function.

scientific article published in March 2009

Effects of cyclodextrins on GM1-gangliosides in fibroblasts from GM1-gangliosidosis patients.

scientific article published on 7 April 2015

Effects of intracerebroventricular administration of 2-hydroxypropyl-β-cyclodextrin in a patient with Niemann-Pick Type C disease

scientific article published on 17 September 2014

Efficacy of 2-Hydroxypropyl-β-cyclodextrin in Niemann-Pick Disease Type C Model Mice and Its Pharmacokinetic Analysis in a Patient with the Disease

scientific article published on 01 January 2015

Ethyl pyruvate attenuates acetaminophen-induced liver injury and prevents cellular injury induced by N-acetyl-p-benzoquinone imine.

scientific article published in February 2018

Evaluation of the vancomycin dosage regimen based on serum creatinine used in the neonatal intensive care unit

scientific article published on 01 December 2011

Evaluation of three-dimensional cultured HepG2 cells in a nano culture plate system: an in vitro human model of acetaminophen hepatotoxicity.

scientific article

Factors affecting serum albumin in the perioperative period of colorectal surgery: a retrospective study

scientific article published on 3 November 2015

HPGCD outperforms HPBCD as a potential treatment for Niemann-Pick disease type C during disease modeling with iPS cells.

scientific article published on April 2015

In Vitro and In Vivo Evaluation of 6-O-α-Maltosyl-β-Cyclodextrin as a Potential Therapeutic Agent Against Niemann-Pick Disease Type C ⬇️

scientific article published on 06 March 2019

In vitro evaluation of 2-hydroxyalkylated β-cyclodextrins as potential therapeutic agents for Niemann-Pick Type C disease.

scientific article published on 30 April 2016

In vivo Efficacy and Safety Evaluation of Lactosyl-β-cyclodextrin as a Therapeutic Agent for Hepatomegaly in Niemann-Pick Type C Disease

scientific article published on 25 May 2019

Influence of Npc1 genotype on the toxicity of hydroxypropyl-β-cyclodextrin, a potentially therapeutic agent, in Niemann-Pick Type C disease models.

scientific article published on 11 January 2014

Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs.

scientific article published in April 2004

Oxidative stress in early stage of acute lung injury induced with oleic acid in guinea pigs.

scientific article published in April 2003

Ozagrel hydrochloride, a selective thromboxane A₂ synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice.

scientific article

Phosphoenolpyruvate, a glycolytic intermediate, as a cytoprotectant and antioxidant in ex-vivo cold-preserved mouse liver: a potential application for organ preservation.

scientific article published on 16 November 2012

Phosphoenolpyruvic acid, an intermediary metabolite of glycolysis, as a potential cytoprotectant and anti-oxidant in HeLa cells

scientific article published on 01 January 2012

Population pharmacokinetics of doxapram in low-birth-weight Japanese infants with apnea.

scientific article published on 25 September 2014

Potential use of a megamolecular polysaccharide sacran as a hydrogel-based sustained release system

scientific article published on 16 April 2014

Predictive Factors for Efficacy and Safety of Prophylactic Theophylline for Extubation in Infants with Apnea of Prematurity.

scientific article published on 07 July 2016

Preparation of hydrophilic C60(OH)10/2-hydroxypropyl-β-cyclodextrin nanoparticles for the treatment of a liver injury induced by an overdose of acetaminophen.

scientific article

Preventive effect of tranilast on oleic acid-induced lung injury in guinea pigs.

scientific article published in September 2004

Protection afforded by a herbal medicine, Sho-seiryu-to (TJ-19), against oleic acid-induced acute lung injury in guinea-pigs.

scientific article published in July 2009

Protection afforded by pre- or post-treatment with 4-phenylbutyrate against liver injury induced by acetaminophen overdose in mice.

scientific article

Role of 6-O-α-maltosyl-β-cyclodextrin in lysosomal cholesterol deprivation in Npc1-deficient Chinese hamster ovary cells.

scientific article published on 10 November 2017

Synthesis of multi-lactose-appended β-cyclodextrin and its cholesterol-lowering effects in Niemann-Pick type C disease-like HepG2 cells

scientific article published on 03 January 2017

The Late-Stage Protective Effect of Mito-TEMPO against Acetaminophen-Induced Hepatotoxicity in Mouse and Three-Dimensional Cell Culture Models

scientific article published on 09 October 2020

The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice

scientific article published on 21 May 2015

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