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List of works by Alessandra S Eustáquio

A rapid and efficient strategy to identify and recover biosynthetic gene clusters from soil metagenomes

scientific article published on 18 April 2022

Advances in and applications of proteasome inhibitors

scientific article

Biosynthesis of salinosporamides from alpha,beta-unsaturated fatty acids: implications for extending polyketide synthase diversity.

scientific article published on August 2009

Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine

scholarly article

Biosynthetic engineering and fermentation media development leads to gram-scale production of spliceostatin natural products in Burkholderia sp.

scientific article published on 24 November 2015

Burkholderia as a Source of Natural Products

scientific article published on 11 July 2019

Clorobiocin biosynthesis in Streptomyces: identification of the halogenase and generation of structural analogs. ⬇️

scientific article published in March 2003

Cultures of the Marine Bacterium Pseudovibrio denitrificans Ab134 Produce Bromotyrosine-Derived Alkaloids Previously Only Isolated from Marine Sponges.

scientific article published on 13 February 2017

Diazaquinomycin Biosynthetic Gene Clusters from Marine and Freshwater Actinomycetes

scientific article published on 21 March 2019

Discovery and assembly-line biosynthesis of the lymphostin pyrroloquinoline alkaloid family of mTOR inhibitors in Salinispora bacteria. ⬇️

scientific article

Discovery and characterization of a marine bacterial SAM-dependent chlorinase

scientific article

Discovery of New Cyclic Lipodepsipeptide Orfamide N via Partnership with Middle School Students from the Boys and Girls Club

scientific article published on 24 October 2024

Discovery of the lomaiviticin biosynthetic gene cluster in Salinispora pacifica

scientific article

Diversification of polyketide structures via synthase engineering

scientific article published on 10 May 2019

Engineered biosynthesis of antiprotealide and other unnatural salinosporamide proteasome inhibitors.

scientific article published on 31 May 2008

Engineering fluorometabolite production: fluorinase expression in Salinispora tropica Yields Fluorosalinosporamide. ⬇️

scientific article

Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse

scientific article published on 20 January 2017

Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A.

scientific article published in March 2012

Genome Sequence of Marine-Derived sp. Strain F001, a Producer of Akashin A and Diazaquinomycins ⬇️

scientific article published on 09 May 2019

Heterologous Production of Lasso Peptide Capistruin in a Burkholderia Host

scientific article published on 13 January 2020

Heterologous expression of novobiocin and clorobiocin biosynthetic gene clusters

scientific article published on May 2005

Heterologous expression of the diazaquinomycin biosynthetic gene cluster

scientific article published on 15 May 2019

Mechanistic Insights into Water Activation in SAM Hydroxide Adenosyltransferase (duf-62)

scientific article

Merocyclophanes C and D from the Cultured Freshwater Cyanobacterium Nostoc sp. (UIC 10110). ⬇️

scientific article published on 2 March 2017

Mutasynthesis of fluorosalinosporamide, a potent and reversible inhibitor of the proteasome

scientific article

Natural Products and Synthetic Biology: Where We Are and Where We Need To Go

scientific article published on 14 May 2019

NovG, a DNA-binding protein acting as a positive regulator of novobiocin biosynthesis.

scientific article published in June 2005

Novobiocin biosynthesis: inactivation of the putative regulatory gene novE and heterologous expression of genes involved in aminocoumarin ring formation.

scientific article published on 8 May 2003

Production of 8'-halogenated and 8'-unsubstituted novobiocin derivatives in genetically engineered streptomyces coelicolor strains. ⬇️

scientific article published in November 2004

S-Adenosyl-L-methionine hydrolase (adenosine-forming), a conserved bacterial and archaeal protein related to SAM-dependent halogenases.

scientific article published on September 2008

Scytodecamide from the Cultured Scytonema sp. UIC 10036 Expands the Chemical and Genetic Diversity of Cyanobactins

scientific article published on 26 November 2019

Selective overproduction of the proteasome inhibitor salinosporamide A via precursor pathway regulation.

scientific article published on December 2011

Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses.

scientific article

Spliceostatin hemiketal biosynthesis in Burkholderia spp. is catalyzed by an iron/α-ketoglutarate-dependent dioxygenase. ⬇️

scientific article

Structure-activity relationships of aminocoumarin-type gyrase and topoisomerase IV inhibitors obtained by combinatorial biosynthesis

scientific article

The discovery of salinosporamide K from the marine bacterium "Salinispora pacifica" by genome mining gives insight into pathway evolution ⬇️

scientific article

novE and novG act as positive regulators of novobiocin biosynthesis.

scientific article published on 21 June 2008

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