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List of works by Laetitia Linares

A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter

scientific article (publication date: August 2003)

BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization

scientific journal article

Calpain-6 controls the fate of sarcoma stem cells by promoting autophagy and preventing senescence

scientific article published on 06 September 2018

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

scientific article published on 17 April 2017

Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.

scientific article

Chromatin-bound MDM2, a new player in metabolism.

scientific article published on 15 July 2016

Dexamethasone in hyperleukocytic acute myeloid leukemia

scientific article published on 08 March 2018

E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells

scientific article

E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation.

scientific article

E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.

scientific article published on 12 September 2016

FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer.

scientific article published on 29 September 2016

Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF

scientific article

Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2

scientific article

Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia.

scientific article published on 7 March 2016

MDM2 controls gene expression independently of p53 in both normal and cancer cells

scientific article published on 23 July 2018

Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53.

scientific article published in February 2018

Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells

scientific article

Role of the p53 tumor suppressor in metabolism

scientific article

Stable Isotope Labeling Highlights Enhanced Fatty Acid and Lipid Metabolism in Human Acute Myeloid Leukemia

scientific article published on 25 October 2018

TAG-RNAi overcomes off-target effects in cancer models

scientific article published on 26 September 2019

Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma

scientific article published on 01 June 2020

The Yin and the Yang of senescence: is it possible to age without developing cancer?

scientific article published in March 2012

The proteasome regulates HIV-1 transcription by both proteolytic and nonproteolytic mechanisms.

scientific article

The ubiquitin-protein ligase activity of Hdm2 is inhibited by nucleic acids.

scientific article published in November 2003

Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation

scientific article

Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis.

scientific article

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