List of works - Hiromune Ando

1,5-Lactamized sialyl acceptors for various disialoside syntheses: novel method for the synthesis of glycan portions of Hp-s6 and HLG-2 gangliosides

scientific article published on 01 October 2005

A 5-Ureido-Modified Sialyl Donor: A Tool for the Synthesis of α-Sialosides

scientific article published on 03 March 2016

A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1-N9 Neuraminidases: Insight into Neuraminidase-Inhibitor Interactions.

scientific article

A facile method for beta-selenoglycoside synthesis using beta-p-methylbenzoyl selenoglycoside as the selenating unit.

scientific article published in October 2005

A first total synthesis of a hybrid-type ganglioside associated with amyotrophic lateral sclerosis-like disorder

scientific article published on 05 November 2010

A first total synthesis of ganglioside HLG-2

scientific article published on 01 January 2009

A new chemical approach to human ABO histo-blood group type 2 antigens.

scientific article published on 31 December 2013

A synthetic approach to the c-series gangliosides containing sialyl-alpha(2-->8)sialyl-alpha(2-->8)sialic acid: synthesis of ganglioside GT4, alpha(2-->6) GT4 and GT3

scientific article published on 01 May 1997

CD22-Antagonists with nanomolar potency: The synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold ⬇️

scientific article published on February 2, 2011

CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice.

scientific article published on 19 April 2018

Constrained sialic acid donors enable selective synthesis of α-glycosides

scientific article published on 01 May 2019

Design and synthesis of a novel ganglioside ligand for influenza A viruses.

scientific article

Development of Fluorescently Labeled SSEA-3, SSEA-4, and Globo-H Glycosphingolipids for Elucidating Molecular Interactions in the Cell Membrane ⬇️

scientific article published on 07 December 2019

Development of new ganglioside probes and unraveling of raft domain structure by single-molecule imaging.

scientific article

Di-tert-butylsilylene-directed alpha-selective synthesis of 4-methylumbelliferyl T-antigen

scientific article published on 01 September 2005

Efficient Synthesis of the Lewis A Tandem Repeat.

scientific article

Efficient diversification of GM3 gangliosides via late-stage sialylation and dynamic glycan structural studies with 19F solid-state NMR

scientific article published on 01 April 2020

Efficiently synthesizing lacto-ganglio-series gangliosides by using a glucosyl ceramide cassette approach: the total synthesis of ganglioside X2

scientific article published on 14 February 2012

Expanded potential of seleno-carbohydrates as a molecular tool for X-ray structural determination of a carbohydrate-protein complex with single/multi-wavelength anomalous dispersion phasing

scientific article

Extended applications of di-tert-butylsilylene-directed alpha-predominant galactosylation compatible with C2-participating groups toward the assembly of various glycosides

scientific article published on 01 November 2006

Extending the glucosyl ceramide cassette approach: application in the total synthesis of ganglioside GalNAc-GM1b.

scientific article published on 10 December 2013

First synthesis of a pentasaccharide moiety of ganglioside GAA-7 containing unusually modified sialic acids through the use of N-Troc-sialic acid derivative as a key unit

scientific article published on 10 December 2012

Indirect synthetic route to α-l-fucosides via highly stereoselective construction of α-l-galactosides followed by C6-deoxygenation

scientific article published on 23 June 2020

Interaction of platelet endothelial cell adhesion molecule (PECAM) with α2,6-sialylated glycan regulates its cell surface residency and anti-apoptotic role

scientific article

J(77 Se,1 H) and J(77 Se,13 C) couplings of seleno-carbohydrates obtained by 77 Se satellite 1D 13 C spectroscopy and 77 Se selective HR-HMBC spectroscopy

scientific article published on 21 May 2018

Linear synthesis of the Chol-1 ganglioside core tetrasaccharide and disialyl T antigen glycan using a 5-ureido-sialyl donor

scientific article published on 8 November 2017

On-Membrane Dynamic Interplay between Anti-GM1 IgG Antibodies and Complement Component C1q

scientific article published on 24 December 2019

Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions.

scientific article published on 13 November 2017

Raft-based interactions of gangliosides with a GPI-anchored receptor

scientific article published on 04 April 2016

Renewed synthetic approach to gangliosides exploiting versatile and powerful synthetic units.

scientific article published in January 2010

Revealing the Raft Domain Organization in the Plasma Membrane by Single-Molecule Imaging of Fluorescent Ganglioside Analogs.

scientific article published on 31 October 2017

Sialyl LewisX mimic-decorated liposomes for anti-angiogenic everolimus delivery to E-selectin expressing endothelial cells

scientific article published on 02 July 2019

Six independent fucose-binding sites in the crystal structure of Aspergillus oryzae lectin

scientific article

Solid-Phase Capture-Release Strategy Applied to Oligosaccharide Synthesis on a Soluble Polymer Support This work was supported in part by the Mizutani Foundation for Glycoscience (grant to Y.I.), the RIKEN Presidential Fund (grant to S.M.), and the

article published in 2001

Stereoselective Synthesis of Diglycosyl Diacylglycerols with Glycosyl Donors Bearing a β-Stereodirecting 2,3-Naphthalenedimethyl Protecting Group

scientific article published on 30 November 2020

Structure-Activity Relationship Study of the Neuritogenic Potential of the Glycan of Starfish Ganglioside LLG-3 (‡).

scientific article

Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection

scientific article

Studies on the alpha-(1-->4)- and alpha-(1-->8)-fucosylation of sialic acid for the total assembly of the glycan portions of complex HPG-series gangliosides

scientific article published on 05 April 2006

Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates.

scientific article published on 7 June 2009

Syntheses of Fluorescent Gangliosides for the Studies of Raft Domains.

scientific article published on 18 July 2017

Synthesis and Functional Characterization of Novel Sialyl LewisX Mimic-Decorated Liposomes for E-selectin-Mediated Targeting to Inflamed Endothelial Cells

scientific article published on 13 February 2017

Synthesis and Glycan-Protein Interaction Studies of Se-Sialosides by 77Se NMR

scientific article published on 08 August 2019

Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems

scientific article published on 01 July 2014

Synthesis of a novel asparagine-linked heptasaccharide structure via p-methoxybenzyl-assisted beta-mannosylation

scientific article published on 01 September 2000

Synthesis of novel selenapenams, selenacephems, and selenazepines using a 2-(trimethylsilyl)ethyl protection approach.

scientific article published on 25 September 2007

Synthesis of seleno-fucose compounds and their application to the X-ray structural determination of carbohydrate-lectin complexes using single/multi-wavelength anomalous dispersion phasing.

scientific article published on 19 December 2016

Synthesis of the disialic acid-embedded glycan part of ganglioside HPG-1

scientific article published on 07 October 2011

Synthesis of the glycan moiety of ganglioside HPG-7 with an unusual trimer of sialic acid as the inner sugar residue

scientific article published on 21 July 2011

Synthetic approach toward complexity of sialic acid-containing glycans

scientific article

The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo.

scientific article

The Origin of High Stereoselectivity in Di-tert-butylsilylene-Directed α-Galactosylation

scientific article published on 20 September 2016

The Total Synthesis of Starfish Ganglioside GP3 Bearing a Unique Sialyl Glycan Architecture

scientific article published on 12 May 2016

The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin

scientific article

The total synthesis of the neurogenic ganglioside LLG-3 isolated from the starfish Linckia laevigata.

scientific article published on 7 February 2011

Total Synthesis of Sialyl Inositol Phosphosphingolipids CJP-2, CJP-3, and CJP-4 Isolated from Feather Star Comanthus japonica

scientific article published on 22 May 2019

Total syntheses of disulphated glycosphingolipid SB1a and the related monosulphated SM1a.

scientific article published on 24 September 2015

Unraveling of Lipid Raft Organization in Cell Plasma Membranes by Single-Molecule Imaging of Ganglioside Probes

scientific article published on 01 January 2018

p- tert-Butyl Groups Improve the Utility of Aromatic Protecting Groups in Carbohydrate Synthesis

scientific article published on 30 May 2019

List of works by Hiromune Ando

1,5-Lactamized sialyl acceptors for various disialoside syntheses: novel method for the synthesis of glycan portions of Hp-s6 and HLG-2 gangliosides

A 5-Ureido-Modified Sialyl Donor: A Tool for the Synthesis of α-Sialosides

A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1-N9 Neuraminidases: Insight into Neuraminidase-Inhibitor Interactions.

A facile method for beta-selenoglycoside synthesis using beta-p-methylbenzoyl selenoglycoside as the selenating unit.

A first total synthesis of a hybrid-type ganglioside associated with amyotrophic lateral sclerosis-like disorder

A first total synthesis of ganglioside HLG-2

A new chemical approach to human ABO histo-blood group type 2 antigens.

A synthetic approach to the c-series gangliosides containing sialyl-alpha(2-->8)sialyl-alpha(2-->8)sialic acid: synthesis of ganglioside GT4, alpha(2-->6) GT4 and GT3

CD22-Antagonists with nanomolar potency: The synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold ⬇️

CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice.

Constrained sialic acid donors enable selective synthesis of α-glycosides

Design and synthesis of a novel ganglioside ligand for influenza A viruses.

Development of Fluorescently Labeled SSEA-3, SSEA-4, and Globo-H Glycosphingolipids for Elucidating Molecular Interactions in the Cell Membrane ⬇️

Development of new ganglioside probes and unraveling of raft domain structure by single-molecule imaging.

Di-tert-butylsilylene-directed alpha-selective synthesis of 4-methylumbelliferyl T-antigen

Efficient Synthesis of the Lewis A Tandem Repeat.

Efficient diversification of GM3 gangliosides via late-stage sialylation and dynamic glycan structural studies with 19F solid-state NMR

Efficiently synthesizing lacto-ganglio-series gangliosides by using a glucosyl ceramide cassette approach: the total synthesis of ganglioside X2

Expanded potential of seleno-carbohydrates as a molecular tool for X-ray structural determination of a carbohydrate-protein complex with single/multi-wavelength anomalous dispersion phasing

Extended applications of di-tert-butylsilylene-directed alpha-predominant galactosylation compatible with C2-participating groups toward the assembly of various glycosides

Extending the glucosyl ceramide cassette approach: application in the total synthesis of ganglioside GalNAc-GM1b.

First synthesis of a pentasaccharide moiety of ganglioside GAA-7 containing unusually modified sialic acids through the use of N-Troc-sialic acid derivative as a key unit

Indirect synthetic route to α-l-fucosides via highly stereoselective construction of α-l-galactosides followed by C6-deoxygenation

Interaction of platelet endothelial cell adhesion molecule (PECAM) with α2,6-sialylated glycan regulates its cell surface residency and anti-apoptotic role

J(77 Se,1 H) and J(77 Se,13 C) couplings of seleno-carbohydrates obtained by 77 Se satellite 1D 13 C spectroscopy and 77 Se selective HR-HMBC spectroscopy

Linear synthesis of the Chol-1 ganglioside core tetrasaccharide and disialyl T antigen glycan using a 5-ureido-sialyl donor

On-Membrane Dynamic Interplay between Anti-GM1 IgG Antibodies and Complement Component C1q

Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions.

Raft-based interactions of gangliosides with a GPI-anchored receptor

Renewed synthetic approach to gangliosides exploiting versatile and powerful synthetic units.

Revealing the Raft Domain Organization in the Plasma Membrane by Single-Molecule Imaging of Fluorescent Ganglioside Analogs.

Sialyl LewisX mimic-decorated liposomes for anti-angiogenic everolimus delivery to E-selectin expressing endothelial cells

Six independent fucose-binding sites in the crystal structure of Aspergillus oryzae lectin

Solid-Phase Capture-Release Strategy Applied to Oligosaccharide Synthesis on a Soluble Polymer Support This work was supported in part by the Mizutani Foundation for Glycoscience (grant to Y.I.), the RIKEN Presidential Fund (grant to S.M.), and the

Stereoselective Synthesis of Diglycosyl Diacylglycerols with Glycosyl Donors Bearing a β-Stereodirecting 2,3-Naphthalenedimethyl Protecting Group

Structure-Activity Relationship Study of the Neuritogenic Potential of the Glycan of Starfish Ganglioside LLG-3 (‡).

Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection

Studies on the alpha-(1-->4)- and alpha-(1-->8)-fucosylation of sialic acid for the total assembly of the glycan portions of complex HPG-series gangliosides

Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates.

Syntheses of Fluorescent Gangliosides for the Studies of Raft Domains.

Synthesis and Functional Characterization of Novel Sialyl LewisX Mimic-Decorated Liposomes for E-selectin-Mediated Targeting to Inflamed Endothelial Cells

Synthesis and Glycan-Protein Interaction Studies of Se-Sialosides by 77Se NMR

Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems

Synthesis of a novel asparagine-linked heptasaccharide structure via p-methoxybenzyl-assisted beta-mannosylation

Synthesis of novel selenapenams, selenacephems, and selenazepines using a 2-(trimethylsilyl)ethyl protection approach.

Synthesis of seleno-fucose compounds and their application to the X-ray structural determination of carbohydrate-lectin complexes using single/multi-wavelength anomalous dispersion phasing.

Synthesis of the disialic acid-embedded glycan part of ganglioside HPG-1

Synthesis of the glycan moiety of ganglioside HPG-7 with an unusual trimer of sialic acid as the inner sugar residue

Synthetic approach toward complexity of sialic acid-containing glycans

The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo.

The Origin of High Stereoselectivity in Di-tert-butylsilylene-Directed α-Galactosylation

The Total Synthesis of Starfish Ganglioside GP3 Bearing a Unique Sialyl Glycan Architecture

The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin

The total synthesis of the neurogenic ganglioside LLG-3 isolated from the starfish Linckia laevigata.

Total Synthesis of Sialyl Inositol Phosphosphingolipids CJP-2, CJP-3, and CJP-4 Isolated from Feather Star Comanthus japonica

Total syntheses of disulphated glycosphingolipid SB1a and the related monosulphated SM1a.

Unraveling of Lipid Raft Organization in Cell Plasma Membranes by Single-Molecule Imaging of Ganglioside Probes

p- tert-Butyl Groups Improve the Utility of Aromatic Protecting Groups in Carbohydrate Synthesis