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List of works by Aled Clayton

A clinical grade poly I:C-analogue (Ampligen) promotes optimal DC maturation and Th1-type T cell responses of healthy donors and cancer patients in vitro.

scientific article

A novel community driven software for functional enrichment analysis of extracellular vesicles data.

scientific article

Analysis of urinary microRNAs in chronic kidney disease.

scientific article published on August 2012

Anti-viral cytotoxic T cells inhibit the growth of cancer cells with antibody targeted HLA class I/peptide complexes in SCID mice

scientific article published on 01 April 2002

Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59.

scientific article published in February 2003

Cancer cells use exosomes as tools to manipulate immunity and the microenvironment ⬇️

scientific article published on January 1, 2012

Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production.

scientific article published on 15 June 2011

Cancer exosomes trigger fibroblast to myofibroblast differentiation

scientific article

Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts

scientific article

Cell surface heparan sulfate proteoglycans control the response of renal interstitial fibroblasts to fibroblast growth factor-2

scientific article published on 01 June 2001

Cerebrospinal fluid extracellular vesicle enrichment for protein biomarker discovery in neurological disease; multiple sclerosis.

scientific article published on 3 September 2017

Characterisation of adipocyte-derived extracellular vesicles released pre- and post-adipogenesis

scientific article

Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles

scientific article published on 01 August 2019

Coronary Artery-Bypass-Graft Surgery Increases the Plasma Concentration of Exosomes Carrying a Cargo of Cardiac MicroRNAs: An Example of Exosome Trafficking Out of the Human Heart with Potential for Cardiac Biomarker Discovery

scientific article

Cross-Presentation of the Oncofetal Tumor Antigen 5T4 from Irradiated Prostate Cancer Cells--A Key Role for Heat-Shock Protein 70 and Receptor CD91.

scientific article

Cross-presentation of the oncofoetal tumor antigen 5T4 from irradiated prostate cancer cells - a key role for Hsp70.

scientific article published on 6 November 2014

Differential Proteome Analysis of Extracellular Vesicles from Breast Cancer Cell Lines by Chaperone Affinity Enrichment.

scientific article published on 8 October 2017

Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes.

scientific article published on 20 January 2014

Dominant immunosuppression of dendritic cell function by prostate-cancer-derived exosomes.

scientific article published on 3 September 2017

EVpedia: a community web portal for extracellular vesicles research

scientific article

Enhancement of T cell responses as a result of synergy between lower doses of radiation and T cell stimulation

scientific article published on 5 March 2014

Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies

scientific article published on 22 March 2018

Extracellular vesicles as modulators of the cancer microenvironment.

scientific article published on 07 February 2015

Extracellular vesicles in the tumour microenvironment.

scientific article

Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic

scientific article

How pure are your vesicles?

scientific article published on 10 January 2013

Human Tumor-Derived Exosomes Selectively Impair Lymphocyte Responses to Interleukin-2

article

Human tumor-derived exosomes down-modulate NKG2D expression.

scientific article

Increased exosome production from tumour cell cultures using the Integra CELLine Culture System.

scientific article

Induction of heat shock proteins in B-cell exosomes.

scientific article

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Preparation of human ovarian cancer ascites-derived exosomes for a clinical trial

scientific article published on 01 September 2005

Pro-Inflammatory Priming of Umbilical Cord Mesenchymal Stromal Cells Alters the Protein Cargo of Their Extracellular Vesicles

scientific article published on 16 March 2020

Prostaglandin E2-mediated adenosinergic effects on CD14+ cells: Self-amplifying immunosuppression in cancer.

scientific article published on 8 December 2016

Prostate stromal cell proteomics analysis discriminates normal from tumour reactive stromal phenotypes.

scientific article published on 25 February 2016

Proteomics analysis of bladder cancer exosomes.

scientific article

Proteomics analysis of cancer exosomes using a novel modified aptamer-based array (SOMAscan™) platform.

scientific article published on 06 February 2014

Proteomics analysis of vesicles isolated from plasma and urine of prostate cancer patients using a multiplex, aptamer-based protein array.

scientific article published on 29 June 2016

Ready-made chromatography columns for extracellular vesicle isolation from plasma

scientific article

Recovery of CD8+ T-cell function during systemic chemotherapy in advanced ovarian cancer.

scientific article published in August 2005

Resistance of CD45RA- T cells to apoptosis and functional impairment, and activation of tumor-antigen specific T cells during radiation therapy of prostate cancer.

scientific article published on 14 June 2010

Resistance to HER2-targeted anti-cancer drugs is associated with immune evasion in cancer cells and their derived extracellular vesicles.

scientific article published on 11 August 2017

Stabilization of Urinary MicroRNAs by Association with Exosomes and Argonaute 2 Protein.

scientific article published on 14 September 2015

Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017.

scientific article

The 2nd United Kingdom Extracellular Vesicle Forum Meeting Abstracts: 15 December 2015, Hadyn Ellis Building, Cardiff University

scientific article published on 23 February 2016

The rationale for combined chemo/immunotherapy using a Toll-like receptor 3 (TLR3) agonist and tumour-derived exosomes in advanced ovarian cancer

scientific article published on 01 March 2005

Tumor stroma-derived factors skew monocyte to dendritic cell differentiation toward a suppressive CD14(+) PD-L1(+) phenotype in prostate cancer.

scientific article published on October 2014

Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation

scientific article

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