List of works - Anna Dimberg

Activation of myeloid and endothelial cells by CD40L gene therapy supports T-cell expansion and migration into the tumor microenvironment

scientific article

Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma

scientific article published on 05 July 2021

CD40L gene therapy tilts the myeloid cell profile and promotes infiltration of activated T lymphocytes

scientific article published on 31 January 2014

CD93 promotes integrin-β1 activation and fibronectin fibrillogenesis during tumor angiogenesis.

scientific article

Chemokines in angiogenesis.

scientific article published on January 2010

Consensus guidelines for the use and interpretation of angiogenesis assays

article

Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer.

scientific article published on 6 February 2007

FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin

scientific article published on 17 September 2007

Heparanase Promotes Glioma Progression and Is Inversely Correlated with Patient Survival.

scientific article published on 26 August 2016

IDH-mutation Status is Associated with Distinct Vascular Gene Expression Signatures in Lower Grade Gliomas.

scientific article

IFN-gamma-induced upregulation of Fcgamma-receptor-I during activation of monocytic cells requires the PKR and NFkappaB pathways.

scientific article published on 3 March 2006

Inhibition of monocytic differentiation by phosphorylation-deficient Stat1 is associated with impaired expression of Stat2, ICSBP/IRF8 and C/EBPepsilon

scientific article

Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1-/- embryonic stem cells shows early priming of endothelial precursors.

scientific article published on 16 August 2007

Local checkpoint inhibition of CTLA-4 as a monotherapy or in combination with anti-PD1 prevents the growth of murine bladder cancer.

scientific article

Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals.

scientific article published on 12 June 2015

Next-generation pathology--surveillance of tumor microecology

scientific article

Ninein is expressed in the cytoplasm of angiogenic tip-cells and regulates tubular morphogenesis of endothelial cells.

scientific article

Osteoglycin - A switch from angiogenesis to T-cell recruitment?

scientific article published on 17 August 2018

Pharmacological targeting of peptidylarginine deiminase 4 prevents cancer-associated kidney injury in mice

scientific article published on 20 April 2017

Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells.

scientific article published on 28 October 2016

Pleiotrophin is a driver of vascular abnormalization in glioblastoma.

scientific article published on 18 February 2016

Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone.

scientific article published on 24 December 2003

Region-by-region analysis of PET, MRI, and histology in en bloc-resected oligodendrogliomas reveals intra-tumoral heterogeneity.

scientific article

Retinoic acid-induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E and posttranscriptional up-regulation of p27(Kip1).

scientific article published in March 2002

Retinoic acid-induced cell cycle arrest of human myeloid cell lines.

scientific article published on October 2003

Ser727/Tyr701-phosphorylated Stat1 is required for the regulation of c-Myc, cyclins, and p27Kip1 associated with ATRA-induced G0/G1 arrest of U-937 cells.

scientific article published on 13 March 2003

Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus.

scientific article published on 23 May 2017

Subtyping of gliomas of various WHO grades by the application of immunohistochemistry.

scientific article

Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment

scientific article published on July 2016

The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells.

scientific article published on 28 February 2017

The glioblastoma vasculature as a target for cancer therapy

scientific article

The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/β1 integrin complex in endothelial cell adhesion and migration

scientific article published on 28 May 2019

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer

scientific article

Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization.

scientific article

Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

scientific article

Tumor angiogenesis: causes, consequences, challenges and opportunities

scientific article published on 06 November 2019

Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

scientific article published on 09 March 2020

Tumor-Induced Local and Systemic Impact on Blood Vessel Function

scientific article

Tumor-induced neutrophil extracellular traps-drivers of systemic inflammation and vascular dysfunction

scientific article

VEGF receptor signalling - in control of vascular function

scientific article (publication date: May 2006)

VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation.

scientific article published on 31 October 2014

Vascular Targeting to Increase the Efficiency of Immune Checkpoint Blockade in Cancer

scientific article published on 21 December 2018

Vascular endothelial growth factor receptor 2 (VEGFR-2) signalling activity in paediatric pilocytic astrocytoma is restricted to tumour endothelial cells.

scientific article

αB-Crystallin regulates expansion of CD11b⁺Gr-1⁺ immature myeloid cells during tumor progression.

scientific article

αB-crystallin/HspB5 regulates endothelial-leukocyte interactions by enhancing NF-κB-induced up-regulation of adhesion molecules ICAM-1, VCAM-1 and E-selectin.

scientific article published on 9 August 2013

List of works by Anna Dimberg

Activation of myeloid and endothelial cells by CD40L gene therapy supports T-cell expansion and migration into the tumor microenvironment

Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma

CD40L gene therapy tilts the myeloid cell profile and promotes infiltration of activated T lymphocytes

CD93 promotes integrin-β1 activation and fibronectin fibrillogenesis during tumor angiogenesis.

Chemokines in angiogenesis.

Consensus guidelines for the use and interpretation of angiogenesis assays

Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer.

FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin

Heparanase Promotes Glioma Progression and Is Inversely Correlated with Patient Survival.

IDH-mutation Status is Associated with Distinct Vascular Gene Expression Signatures in Lower Grade Gliomas.

IFN-gamma-induced upregulation of Fcgamma-receptor-I during activation of monocytic cells requires the PKR and NFkappaB pathways.

Inhibition of monocytic differentiation by phosphorylation-deficient Stat1 is associated with impaired expression of Stat2, ICSBP/IRF8 and C/EBPepsilon

Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1-/- embryonic stem cells shows early priming of endothelial precursors.

Local checkpoint inhibition of CTLA-4 as a monotherapy or in combination with anti-PD1 prevents the growth of murine bladder cancer.

Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals.

Next-generation pathology--surveillance of tumor microecology

Ninein is expressed in the cytoplasm of angiogenic tip-cells and regulates tubular morphogenesis of endothelial cells.

Osteoglycin - A switch from angiogenesis to T-cell recruitment?

Pharmacological targeting of peptidylarginine deiminase 4 prevents cancer-associated kidney injury in mice

Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells.

Pleiotrophin is a driver of vascular abnormalization in glioblastoma.

Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone.

Region-by-region analysis of PET, MRI, and histology in en bloc-resected oligodendrogliomas reveals intra-tumoral heterogeneity.

Retinoic acid-induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E and posttranscriptional up-regulation of p27(Kip1).

Retinoic acid-induced cell cycle arrest of human myeloid cell lines.

Ser727/Tyr701-phosphorylated Stat1 is required for the regulation of c-Myc, cyclins, and p27Kip1 associated with ATRA-induced G0/G1 arrest of U-937 cells.

Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus.

Subtyping of gliomas of various WHO grades by the application of immunohistochemistry.

Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment

The cancer-immunity cycle as rational design for synthetic cancer drugs: Novel DC vaccines and CAR T-cells.

The glioblastoma vasculature as a target for cancer therapy

The small GTPase Rab5c is a key regulator of trafficking of the CD93/Multimerin-2/β1 integrin complex in endothelial cell adhesion and migration

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer

Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization.

Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

Tumor angiogenesis: causes, consequences, challenges and opportunities

Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

Tumor-Induced Local and Systemic Impact on Blood Vessel Function

Tumor-induced neutrophil extracellular traps-drivers of systemic inflammation and vascular dysfunction

VEGF receptor signalling - in control of vascular function

VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation.

Vascular Targeting to Increase the Efficiency of Immune Checkpoint Blockade in Cancer

Vascular endothelial growth factor receptor 2 (VEGFR-2) signalling activity in paediatric pilocytic astrocytoma is restricted to tumour endothelial cells.

αB-Crystallin regulates expansion of CD11b⁺Gr-1⁺ immature myeloid cells during tumor progression.

αB-crystallin/HspB5 regulates endothelial-leukocyte interactions by enhancing NF-κB-induced up-regulation of adhesion molecules ICAM-1, VCAM-1 and E-selectin.