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List of works by Tom Eirik Mollnes

'Stealth' corporate innovation: an emerging threat for therapeutic drug development

scientific article published on 01 November 2019

A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity

scientific article published on 16 September 2020

A Neoepitope‐Based Enzyme Immunoassay for Quantification of C1‐Inhibitor in Complex with C1r and C1s ⬇️

scientific article published on 01 December 1997

A New Model for Evaluation of Biocompatibility: Combined Determination of Neoepitopes in Blood and on Artificial Surfaces Demonstrates Reduced Complement Activation by Immobilization of Heparin

scientific article published on 01 September 1995

A complement C5 gene mutation, c.754G>A:p.A252T, is common in the Western Cape, South Africa and found to be homozygous in seven percent of Black African meningococcal disease cases

scientific article published on 19 December 2014

A helicopter flight does not induce significant changes in systemic biomarker profiles

scientific article published on 01 January 2009

A new dynamic porcine model of meningococcal shock

scientific article

A novel enzyme immunoassay for plasma thrombospondin. Comparison with beta-thromboglobulin as platelet activation marker in vitro and in vivo

scientific article published on 01 July 2000

A novel method for direct measurement of complement convertases activity in human serum.

scientific article

A parameter for IL-10 and TGF-ß mediated regulation of HIV-1 specific T cell activation provides novel information and relates to progression markers

scientific article published on 09 January 2014

A unique epitope exposed in native complement component C9 and hidden in the terminal SC5b-9 complex enables selective detection and quantification of non-activated C9

scientific article published on 01 June 1987

A vital role for complement in heart disease

scientific article published on 16 July 2014

Acquired C3 deficiency in patients with alcoholic cirrhosis predisposes to infection and increased mortality

scientific article

Activation of coagulation and platelets by candidate membranes of implantable devices in a whole blood model without soluble anticoagulant ⬇️

scientific article published on September 4, 2012

Activation of complement during apheresis

scientific article published on 01 June 1991

Activation of complement, kallikrein-kinin, fibrinolysis and coagulation systems by urinary catheters. Effect of time and temperature in biocompatibility studies.

scientific article published on January 1991

Activation of polymorphonuclear leukocytes by candidate biomaterials for an implantable glucose sensor

scientific article published on November 2011

Activation of the complement, coagulation, fibrinolytic and kallikrein-kinin systems during attacks of hereditary angioedema

scientific article published on 01 August 1996

Activation of the complement, coagulation, fibrinolytic and kallikrein-kinin systems during attacks of hereditary angioedema

scientific article published on 01 June 1996

Activation-dependent antigenic changes of human C3.

scientific article published on January 1989

Activation-dependent epitopes in the terminal complement pathway.

scientific article published on January 1989

Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock

scientific article published on 9 February 2018

Adhesion molecule expression and complement activation in vessel walls in synovial tissue from patients with chronic inflammatory joint disease

scientific article published on 01 September 1996

Advances in assay of complement function and activation ⬇️

scientific article published on 02 June 2011

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population

Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood

scientific article published on 03 November 2021

Albumin lavage does not improve the outcome of meconium aspiration syndrome

scientific article

Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII.

scientific article published on 30 May 2017

Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model

scientific article

Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation

scientific article published on 15 March 2016

Alterations in the terminal complement pathway in leukopenic children with malignant diseases during episodes with evidence of infection

scientific article published in January 1989

Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation

scientific article published on 16 March 2016

Alternative Pathway Activation of Complement in Laparoscopic and Open Rectal Surgery ⬇️

scientific article published on 01 July 2012

An ex vivo Perfusion Model to Evaluate Hyperacute Rejection in a Discordant Pig-to-Human Combination ⬇️

scientific article published on 01 January 1998

An international serum standard for application in assays to detect human complement activation products

scientific article published on 17 June 2013

Analysis of cytokines

scientific article published on 06 January 2020

Anti-TNF treatment of baboons with sepsis reduces TNF-alpha, IL-6 and IL-8, but not the degree of complement activation

scientific article published on 01 November 1998

Anti-inflammatory effects of C1-Inhibitor in porcine and human whole blood are independent of its protease inhibition activity

scientific article published on 26 August 2009

Anti-inflammatory effects of non-statin low-density lipoprotein cholesterol-lowering drugs: an unused potential?

scientific article published on 05 June 2020

Antibodies reactive to cleaved sites in complement proteins enable highly specific measurement of soluble markers of complement activation

scientific article published on 18 March 2015

Antigenic crossreactivity of the alpha subunit of complement component C8 with the cysteine-rich domain shared by complement component C9 and low density lipoprotein receptor

scientific article published on June 1986

Antiphospholipid Antibodies are Associated with Low Levels of Complement C3 and C4 in Patients with Systemic Lupus Erythematosus

scientific article published on 01 August 2016

Arginine catabolic mobile element is associated with low antibiotic resistance and low pathogenicity in Staphylococcus epidermidis from neonates

scientific article published on September 2010

Artificial surface-induced cytokine synthesis: effect of heparin coating and complement inhibition

scientific article

Artificial surface-induced inflammation relies on complement factor 5: proof from a deficient person

scientific article

Assessments of skin and tongue microcirculation reveals major changes in porcine sepsis ⬇️

scientific article published on November 18, 2010

Association of ficolin-3 with severity and outcome of chronic heart failure

scientific article

Associations between complement pathways activity, mannose-binding lectin, and odds of unprovoked venous thromboembolism

scientific article published on 30 June 2018

Atrial Fibrillation: Inflammation in Disguise? ⬇️

scientific article published on August 1, 2013

Attenuation of changes in leukocyte surface markers and complement activation with heparin-coated cardiopulmonary bypass

scientific article published on January 1997

Author Correction: 'Stealth' corporate innovation: an emerging threat for therapeutic drug development

scientific article published on 01 November 2019

Avoiding ambient air in test tubes during incubations of human whole-blood minimizes complement background activation

scientific article published on 06 October 2020

Biocompatibility and pathways of initial complement pathway activation with Phisio- and PMEA-coated cardiopulmonary bypass circuits during open-heart surgery

scientific article published on 22 December 2010

Biocompatibility of Urinary Catheters. Effect on Complement Activation

scientific article published on 01 April 1989

Biocompatibility of candidate materials for an implantable glucose sensor in terms of complement and neutrophil activating properties

Biocompatibility of extracorporeal circulation. In vitro comparison of heparin-coated and uncoated oxygenator circuits

Biocompatibility of white cell filters as evaluated by complement activation

scientific article published on 01 July 1992

Biomarker profile in off-pump and on-pump coronary artery bypass grafting surgery in low-risk patients

scientific article published in June 2008

Biphasic Release of the Alarmin High Mobility Group Box 1 Protein Early After Trauma Predicts Poor Clinical Outcome

scientific article published on 01 August 2019

Body composition and plasma levels of inflammatory biomarkers in COPD

article

Both plasma- and leukocyte-associated C5a are essential for assessment of C5a generation in vivo

scientific article published on 01 April 1997

Bride and groom in systemic inflammation – The bells ring for complement and Toll in cooperation ⬇️

scientific article published on November 1, 2012

Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes

scientific article

C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release

scientific article published on 20 October 2018

C-reactive protein, infarct size, microvascular obstruction, and left-ventricular remodelling following acute myocardial infarction

scientific article published on 19 March 2009

C1 inhibitor and diagnosis of hereditary angioedema in newborns

scientific article published on 01 February 1994

C1-inhibitor attenuates human serum induced E-selectin expression of pig aortic endothelial cells

scientific article published on 01 February 2001

C1-inhibitor attenuates hyperacute rejection and inhibits complement, leukocyte and platelet activation in an ex vivo pig-to-human perfusion model

scientific article published on May 1999

C1-inhibitor efficiently delays clot development in normal human whole blood and inhibits Escherichia coli-induced coagulation measured by thromboelastometry

scientific article published on 28 April 2016

C1-inhibitor efficiently inhibits Escherichia coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole blood

scientific article published in August 2013

C1-inhibitor reduces the ischaemia-reperfusion injury of skeletal muscles in mice after aortic cross-clamping

scientific article published in December 2002

C1-inhibitor: an anti-inflammatory reagent with therapeutic potential

scientific article

C3 Activation Products, C3 Containing Immune Complexes, the Terminal Complement Complex and Native C9 in Patients with Rheumatoid Arthritis

scientific article published on 01 January 1991

C3 is activated in hereditary angioedema, and C1/C1-inhibitor complexes rise during physical stress in untreated patients

scientific article published on 01 December 1995

C3, C4, and the terminal complement complex differ from C1q by binding predominantly to the antigenic part of solid phase immune complexes.

scientific article

CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray

scientific article published on 23 February 2015

CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs

scientific article

CD14 inhibition improves survival and attenuates thrombo-inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis

scientific article published on 10 November 2020

CD59 efficiently protects human NT2-N neurons against complement-mediated damage

scientific article

COMP-C3b Complexes in Rheumatoid Arthritis with Severe Extraarticular Manifestations

scientific article published on 01 November 2013

Calprotectin and complement activation during major operations with or without cardiopulmonary bypass

scientific article published on 01 March 1993

Candidate inhibitors of porcine complement

scientific article published on 15 November 2006

Centrifugal pump and heparin coating improves cardiopulmonary bypass biocompatibility

scientific article published on 01 October 1996

Changes in cytokines during treatment of elderly, hospitalized psychiatric patients - a naturalistic study

scientific article published on 26 June 2019

Changes in laboratory variables in rheumatoid arthritis patients during a trial of fasting and one-year vegetarian diet.

scientific article published in January 1995

Changes in serum levels of E-selectin correlate to improved glycaemic control and reduced obesity in subjects with the metabolic syndrome

scientific article published in January 2005

Changes in the cytokine network and complement parameters during open heart surgery

scientific article published on 01 March 2003

Characterization of Soluble Terminal Complement Complex Assembled in C8β‐Deficient Plasma and Serum ⬇️

scientific article published on 01 September 1998

Characterization of a Monoclonal Antibody MoAb bH6 Reacting with a Neoepitope of Human C3 Expressed on C3b, iC3b, and C3c

scientific article published on 01 March 1988

Characterization of natural human anti-non-gal antibodies and their effect on activation of porcine gal-deficient endothelial cells

scientific article published on July 2007

Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation

scientific article published on 23 September 2013

Choice of immunoassay to evaluate porcine cytokine levels

scientific article published on 06 October 2020

Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis

scientific article published on 16 May 2016

Cholesterol Crystals Induce Coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor

scientific article published on 03 July 2019

Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF.

scientific article

Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release

scientific article published on 19 February 2014

Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis

scientific article published on 11 September 2020

Chronic fatigue syndrome/myalgic encephalo-myelitis--pathophysiology, diagnosis and treatment

scientific article published on 15 December 2015

Circulating cell-free DNA is elevated in community-acquired bacterial pneumonia and predicts short-term outcome.

scientific article

Clinical and Complement Long-Term Follow-Up of a Pediatric Patient with C3 Mutation-Related Atypical Hemolytic Uremic Syndrome

Clinical experience with microdialysis catheters in pediatric liver transplants

scientific article published on 01 March 2013

Collectin Liver 1 and Collectin Kidney 1 of the Lectin Complement Pathway Are Associated With Mortality After Kidney Transplantation

scientific article published on 24 June 2016

Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome ⬇️

scientific article published on 27 February 2018

Combined Inhibition of Complement and CD14 Attenuates Bacteria-Induced Inflammation in Human Whole Blood More Efficiently Than Antagonizing the Toll-like Receptor 4-MD2 Complex.

scientific article published on 14 March 2016

Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis

scientific article published on 27 February 2017

Combined inhibition of complement C5 and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis

scientific article published on 12 June 2013

Combined inhibition of complement and CD14 abolish E. coli-induced cytokine-, chemokine- and growth factor-synthesis in human whole blood.

scientific article

Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model

scientific article published on 10 February 2014

Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis

scientific article

Common variable immunodeficiency and the complement system; low mannose-binding lectin levels are associated with bronchiectasis

scientific article published in December 2005

Comparable biocompatibility of Phisio- and Bioline-coated cardiopulmonary bypass circuits indicated by the inflammatory response

scientific article published in January 2010

Comparison of a Duraflo II-coated cardiopulmonary bypass circuit and a trillium-coated oxygenator during open-heart surgery

scientific article published in May 2004

Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model

scientific article published on 29 November 2019

Comparison of in vitro and in vivo complement activation by metal and bioabsorbable screws used in anterior cruciate ligament reconstruction

scientific article

Comparison of three oxygenator-coated and one total-circuit-coated extracorporeal devices

scientific article published on 01 March 1999

Complement Activation Correlates With Disease Severity and Contributes to Cytokine Responses in Plasmodium falciparum Malaria

scientific article published on 15 May 2015

Complement Activation Reflects Severity of Meconium Aspiration Syndrome in Newborn Pigs

Complement Activation in 22q11.2 Deletion Syndrome

scientific article published on 09 March 2020

Complement C3 and C5 deficiency affects fracture healing

scientific article

Complement C5a is a key mediator of meconium-induced neutrophil activation

scientific article published on 7 December 2004

Complement Component C5 and TLR Molecule CD14 Mediate Heme-Induced Thromboinflammation in Human Blood

scientific article published on 14 August 2019

Complement activation and bioincompatibility. The terminal complement complex for evaluation and surface modification with heparin for improvement of biomaterials

Complement activation and complement-dependent inflammation by Neisseria meningitidis are independent of lipopolysaccharide

scientific article

Complement activation and cytokine and chemokines release during mediastinitis

scientific article published in March 2003

Complement activation and cytokine response by BioProtein, a bacterial single cell protein

scientific article published on 01 April 2007

Complement activation and endotoxin levels in systemic meningococcal disease

scientific article published on 01 July 1989

Complement activation and plasma levels of C4b-binding protein in critical limb ischemia patients

scientific article published in July 2009

Complement activation and release of interleukin-6 and tumour necrosis factor-α in drained and systemic blood after major orthopaedic surgery ⬇️

scientific article published on 01 February 1998

Complement activation and release of tumour necrosis factor alpha, interleukin-2, interleukin-6 and soluble tumour necrosis factor and interleukin-2 receptors during and after cardiopulmonary bypass in children

scientific article

Complement activation assessed by the plasma terminal complement complex and future risk of venous thromboembolism

scientific article published on 13 May 2019

Complement activation by Pseudomonas aeruginosa biofilms

scientific article published on 01 November 1993

Complement activation by angiographic catheters in vitro

scientific article published on 01 September 1995

Complement activation by candidate biomaterials of an implantable microfabricated medical device

scientific article published on 06 June 2011

Complement activation by cholesterol crystals triggers a subsequent cytokine response

scientific article published on 28 September 2016

Complement activation by extracorporeal circulation: effects of precoating a membrane oxygenator circuit with human whole blood

scientific article published on 01 January 1988

Complement activation by neutrophil granulocytes

scientific article published on 01 February 2008

Complement activation by proposed biomaterials intended for composition of a glucose sensor

article

Complement activation during and after open-heart surgery is only marginally affected by the choice of fluid for volume replacement

scientific article

Complement activation during cardiopulmonary bypass: comparison between the use of large volumes of plasma and dextran 70.

scientific article published in January 1988

Complement activation during extracorporeal circulation. In vitro comparison of Duraflo II heparin-coated and uncoated oxygenator circuits

scientific article published on 01 September 1993

Complement activation during major operations with or without cardiopulmonary bypass

scientific article published on 01 June 1987

Complement activation following multiple injuries

scientific article published on 01 January 1987

Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery

scientific article published on 07 December 2015

Complement activation in early protocol kidney graft biopsies after living-donor transplantation1 ⬇️

scientific article published on April 27, 2003

Complement activation in experimental human malaria infection

scientific article published on 3 May 2007

Complement activation in injured patients occurs immediately and is dependent on the severity of the trauma

scientific article published on 01 September 1998

Complement activation in patients with congestive heart failure: effect of high-dose intravenous immunoglobulin treatment

scientific article published on September 2001

Complement activation in patients with systemic lupus erythematosus without nephritis

scientific article published on 01 October 1999

Complement activation in rheumatoid arthritis evaluated by C3dg and the terminal complement complex

scientific article published on 01 June 1986

Complement activation in septic baboons detected by neoepitope-specific assays for C3b/iC3b/C3c, C5a and the terminal C5b-9 complement complex (TCC)

scientific article published on 01 February 1993

Complement activation induced by purified Neisseria meningitidis lipopolysaccharide (LPS), outer membrane vesicles, whole bacteria, and an LPS-free mutant

scientific article published on 03 January 2002

Complement activation is a crucial pathogenic factor in catastrophic antiphospholipid syndrome

scientific article published on 22 April 2016

Complement activation patterns in atypical haemolytic uraemic syndrome during acute phase and in remission

scientific article

Complement activation with bubble and membrane oxygentors in aortocorpnary bypass grafting

scientific article published on 01 September 1990

Complement analysis in clinic and research

scientific article

Complement analysis in the 21st century

scientific article

Complement analysis tests

scientific article

Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis

scientific article

Complement and coagulation: strangers or partners in crime?

scientific article published on March 2007

Complement and granulocyte activation in two different types of heparinized extracorporeal circuits

scientific article published on 01 December 1995

Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4

scientific article published on 19 December 2018

Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling

scientific article published on 16 January 2020

Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function

scientific article published on 03 March 2017

Complement in Sepsis - when Science meets Clinics

scientific article published on 04 July 2020

Complement in clinical medicine: Clinical trials, case reports and therapy monitoring

scientific article published on 30 May 2017

Complement in inflammatory tissue damage and disease

article

Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis

scientific article

Complement inhibition prevents granulocyte activation caused by candidate biomaterials for an implantable microfabricated device

Complement profile and activation mechanisms by different LDL apheresis systems ⬇️

scientific article published on February 25, 2012

Complement-fixing islet cell antibodies in type-1 diabetes can trigger the assembly of the terminal complement complex on human islet cells and are potentially cytotoxic

scientific article published on 01 June 1996

Complete heparin-coated cardiopulmonary bypass and low heparin dose reduce complement and granulocyte activation

scientific article published on 01 January 1996

Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts

article

Corrigendum to "Changes in cytokines during treatment of elderly, hospitalized psychiatric patients-A naturalistic study" [Psychoneuroendocrinology, 108C (2019), 135-139]

scientific article published on 17 September 2019

Critical roles of complement and antibodies in host defense mechanisms against Neisseria meningitidis as revealed by human complement genetic deficiencies

scientific article

Cyanobacterial LPS antagonist (CyP)-a novel and efficient inhibitor of Escherichia coli LPS-induced cytokine response in the pig

scientific article published on 20 June 2008

Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation

scientific article published on 30 August 2017

Cytokine network in adults with falciparum Malaria and HIV-1: increased IL-8 and IP-10 levels are associated with disease severity

scientific article

Cytokine profiles and diagnoses in elderly, hospitalized psychiatric patients

Cytokine profiling and post-transfusion haemoglobin increment in patients with haematological diseases

scientific article published on 29 August 2018

Cytokine responses, microbial aetiology and short-term outcome in community-acquired pneumonia

scientific article published on 24 November 2017

Cytokine secretion depends on Galalpha(1,3)Gal expression in a pig-to-human whole blood model

scientific article published on May 2008

Cytokines monitored by microdialysis detect rejection earlier than current methods in liver transplantation.

scientific article published on 22 March 2007

Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections

scientific article published on 09 March 2006

Deposition of C3, the terminal complement complex and vitronectin in primary biliary cirrhosis and primary sclerosing cholangitis

Deposits of terminal complement complex (TCC) in muscularis mucosae and submucosal vessels in ulcerative colitis and Crohn's disease of the colon

scientific article

Deposits of terminal complement complex and S-protein on follicular dendritic cells in human lymphoid tissue

Design of a complement mannose-binding lectin pathway-specific activation system applicable at low serum dilutions

article by Morten Harboe et al published June 2006 in Clinical and Experimental Immunology

Detection and quantification of the terminal C5b-9 complex of human complement by a sensitive enzyme-linked immunosorbent assay

scientific article published on 01 August 1984

Development of β-Amino Alcohol Derivatives That Inhibit Toll-like Receptor 4 Mediated Inflammatory Response as Potential Antiseptics ⬇️

scientific article published on June 2, 2011

Dexamethasone reduces bilirubin-induced toxicity and IL-8 and MCP-1 release in human NT2-N neurons

scientific article published on 13 April 2012

Differences in blood activation related to roller/centrifugal pumps and heparin-coated/uncoated surfaces in a cardiopulmonary bypass model circuit

scientific article published on 01 March 1996

Different activation patterns in the plasma kallikrein-kinin and complement systems during coronary bypass surgery

scientific article published in July 1989

Different inflammatory responses induced by three LDL-lowering apheresis columns

scientific article published in January 2009

Different oxygenators for cardiopulmonary bypass lead to varying degrees of human complement activation in vitro

scientific article published on 01 May 1989

Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production

scientific article published in March 2005

Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood

scientific article published on January 2012

Disparity in blood activation by two different heparin-coated cardiopulmonary bypass systems

scientific article published on 01 November 1995

Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis

scientific article published in June 2010

Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice

scientific article published on 30 April 2014

Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets

scientific article

Duraflo II coating of cardiopulmonary bypass circuits reduces complement activation, but does not affect the release of granulocyte enzymes : a European multicentre study

scientific article published on 01 February 1997

Early bedside detection of ischemia and rejection in liver transplants by microdialysis

scientific article published on 01 July 2012

Early protective effect of hypothermia in newborn pigs after hyperoxic, but not after normoxic, reoxygenation

scientific article published in September 2010

Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn

scientific article published on 13 November 2014

Eculizumab treatment efficiently prevents C5 cleavage without C5a generation in vivo

scientific article published on July 2015

Eculizumab-C5 complexes express a C5a neoepitope in vivo: Consequences for interpretation of patient complement analyses

scientific article published on 10 June 2017

Editorial: The Role of Complement in Health and Disease

Effect of Perfusion Fluids on Recovery of Inflammatory Mediators in Microdialysis.

scientific article

Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons

scientific article published on 17 August 2006

Effect of complement inhibition and heparin coating on artificial surface-induced leukocyte and platelet activation

scientific article published in March 2004

Effect of filtration and storage of platelet concentrates on the production of the chemotaxins C5a, interleukin 8, tumor necrosis factor alpha, and leukotriene B4 ⬇️

scientific article published on 01 January 1998

Effect of nephritic factor on C3 and on the terminal pathway of complement in vivo and in vitro

scientific article published in July 1986

Effect of perfusion temperature on the inflammatory response during pediatric cardiac surgery

scientific article published in February 2008

Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement

scientific article published on 13 November 2006

Effect of syringe-assisted liposuction on activation of cascade systems and circulating cells when using the superwet or tumescent technique.

scientific article published in September 1995

Effect of the anticoagulant, storage time and temperature of blood samples on the concentrations of 27 multiplex assayed cytokines - Consequences for defining reference values in healthy humans

scientific article published on 05 June 2017

Effect of time, temperature and additives on a functional assay of C1 inhibitor

scientific article published on 01 August 1994

Effect of time, temperature and anticoagulants on in vitro complement activation: consequences for collection and preservation of samples to be examined for complement activation

scientific article published in September 1988

Effect of whole and fractionated intravenous immunoglobulin on complement in vitro ⬇️

scientific article published on 01 July 1997

Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome: A case report

scientific article published on March 2017

Effects of Natural versus Synthetic Surfactant with SP-B and SP-C Analogs in a Porcine Model of Meconium Aspiration Syndrome

scientific article published on 14 December 2013

Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts

scientific article published on 05 July 2019

Effects of methylprednisolone on complement activation and leukocyte counts during cardiopulmonary bypass

scientific article published on 01 January 1987

Effects on Complement, Granulocytes and Platelets of a Leukocyte-Depletion Filter During in vitro Extracorporeal Circulation ⬇️

scientific article published on 01 January 1997

Electroluminescent TCC, C3dg and fB/Bb epitope assays for profiling complement cascade activation in vitro using an activated complement serum calibration standard.

scientific article

Elevated Complement C3 and C4 Levels are Associated with Postnatal Pregnancy-Related Venous Thrombosis

scientific article published on 29 June 2019

Elevated plasma sTIM-3 levels in severe Covid-19 patients

scientific article published on 21 September 2020

Elutable factors from latex-containing materials activate complement and inhibit cell proliferation. An in vitro biocompatibility study of medical devices

Endotoxin Removal in Septic Shock with the Alteco® LPS Adsorber was Safe But Showed No Benefit Compared to Placebo in the Double-Blind Randomized Controlled Trial - the Asset Study

scientific article published on 26 December 2019

Enzyme immunoassay detection of circulating immune complexes by monoclonal antibodies to C3 neoepitopes with special reference to IgG concentration and to interfering anti-immunoglobulin antibodies

scientific article published on February 1989

Epithelial deposition of immunoglobulin G1 and activated complement (C3b and terminal complement complex) in ulcerative colitis.

scientific article

Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation

scientific article published in September 2002

Ethical aspects of xenotransplantation

scientific article published in February 2002

European Union funded project on the development of a whole complement deficiency screening ELISA-A story of success and an exceptional manager: Mohamed R. Daha

scientific article published on 22 May 2015

Ex vivo model for xenotransplantation

scientific article published on 01 December 1995

Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza

scientific article

Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome

scientific article published in February 2004

Exploration of 27 plasma immune markers: a cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons.

scientific article published on 25 June 2018

Expression of complement regulators and receptors on human NT2-N neurons--effect of hypoxia and reoxygenation

scientific article published on 20 November 2006

Extensive complement activation in hereditary porcine membranoproliferative glomerulonephritis type II (porcine dense deposit disease)

scientific article published in November 1993

Extracorporeal membrane oxygenation using a centrifugal pump and a servo regulator to prevent negative inlet pressure

scientific article published on 01 May 1997

Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo

scientific article

Formation of C5a during cardiopulmonary bypass: inhibition by precoating with heparin

scientific article published on 01 July 1991

Functional analysis of the classical, alternative, and MBL pathways of the complement system: standardization and validation of a simple ELISA.

scientific article published on 15 December 2004

Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response

scientific article

Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy

scientific article

Glomerular monocyte/macrophage influx correlates strongly with complement activation in 1-week protocol kidney allograft biopsies

scientific article published on 01 August 2004

Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) - an ex vivo study with blood from a C5-deficient individual

scientific article published in April 2018

Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency

scientific article published on 16 September 2020

Hematologic and hemostatic changes induced by different columns during LDL apheresis ⬇️

scientific article published on January 1, 2010

Heparin-binding properties of vitronectin are linked to complex formation as illustrated by in vitro polymerization and binding to the terminal complement complex

scientific article published on 01 November 1992

Heparin-coated cardiopulmonary bypass circuits selectively deplete the pattern recognition molecule ficolin-2 of the lectin complement pathway in vivo

scientific article published on February 2015

Heparin-coated cardiopulmonary bypass equipment. I. Biocompatibility markers and development of complications in a high-risk population

scientific article published on 01 April 1999

Heparin-coated cardiopulmonary bypass equipment. II. Mechanisms for reduced complement activation in vivo

scientific article published on 01 April 1999

Hereditary angio-oedema: new clinical observations and autoimmune screening, complement and kallikrein-kinin analyses

scientific article published in February 1996

Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency

scientific article published on March 1995

High MIP-1β Levels in Plasma Predict Long-Term Immunological Nonresponse to Suppressive Antiretroviral Therapy in HIV Infection

scientific article published on August 2015

High and low heparin dose with heparin-coated cardiopulmonary bypass: activation of complement and granulocytes

scientific article published on 01 December 1995

High doses of corticosteroids in total hip replacement. Effects on components of coagulation, fibrinolytic, plasma kallikrein-kinin and complement systems.

scientific article published on April 1989

High ficolin-3 level at the time of transplantation is an independent risk factor for graft loss in kidney transplant recipients

scientific article published in April 2015

High frequency and intensity of drinking may attenuate increased inflammatory cytokine levels of major depression in alcohol-use disorders

scientific article

High mobility group box-1 protein--one step closer to the clinic?

scientific article published on 17 July 2008

High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections

scholarly article by Else Quist-Paulsen et al published 23 November 2018 in Journal of Neuroinflammation

High serum CXCL10 in Rickettsia conorii infection is endothelial cell mediated subsequent to whole blood activation

scientific article

High‐Dose Intravenous Immunoglobulin Treatment Activates Complement In Vivo ⬇️

scientific article published on 01 September 1998

Hirudin versus heparin for use in whole blood in vitro biocompatibility models

scientific article published on 01 June 2009

Human Endothelial Cell Activation by Escherichia coli and Staphylococcus aureus Is Mediated by TNF and IL-1β Secondarily to Activation of C5 and CD14 in Whole Blood.

scientific article published on 22 January 2016

Human complement activation by polygeline and dextran 70

scientific article published on 01 March 1994

Human complement-activating immunoglobulin (Ig)G3 antibodies are essential for porcine endothelial cell activation

scientific article published in May 2006

Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature

scholarly article

Human serum-induced expression of E-selectin on porcine aortic endothelial cells in vitro is totally complement mediated

scientific article published on 01 December 2001

Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 and IgM anti-Gal antibodies

scientific article published in September 2002

Hypothesis: combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response.

scientific article published on January 2008

IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction

IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy

scientific article published on 15 January 2015

Identification of a C → T Mutation in the Reactive‐Site Coding Region of the C1‐Inhibitor Gene and its Detection by an Improved Mutation‐Specific Polymerase Chain Reaction Method ⬇️

scientific article published on 01 March 1998

Identification of a human C5 beta-chain epitope exposed in the native complement component but concealed in the SC5b-9 complex

scientific article published on 01 September 1988

IgG and IgA subclass distribution of total immunoglobulin and rheumatoid factors in rheumatoid tissue plasma cells

scientific article published on 01 January 1990

IgG subclass distribution and complement activation ability of autoantibodies to neutrophil cytoplasmic antigens (ANCA)

scientific article published on 01 January 1994

Immobilized heparin inhibits the increase in leukocyte surface expression of adhesion molecules

scientific article published on 01 April 1997

Immunoglobulin Prolongs Survival of Pig Kidneys Perfused Ex Vivo with Human Blood ⬇️

scientific article published on June 1, 1998

Immunohistochemical detection of terminal complement complex and S protein in normal and pre-eclamptic placentae

scientific article published on May 1990

Immunohistochemical detection of the membrane and fluid-phase terminal complement complexes C5b-9(m) and SC5b-9. Consequences for interpretation and terminology

scientific article published on 01 October 1987

Impact of the complement lectin pathway on cytomegalovirus disease early after kidney transplantation

scientific article

Impaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency

scientific article published on 01 July 2019

In vitro evaluation of PHISIO-coated sets for pediatric cardiac surgery

scientific article published in April 2009

In vitro evaluation of new surface coatings for extracorporeal circulation

scientific article published on 01 January 1999

Increased Amounts of C4-Containing Immune Complexes and Inefficient Activation of C3 and the Terminal Complement Pathway in a Patient with Homozygous C2 Deficiency and Systemic Lupus Erythematosus

scientific article published on 01 January 1990

Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis

scientific article published on 06 September 2019

Increased Interleukin-6 and Macrophage Chemoattractant Protein-1 are associated with Respiratory Failure in COVID-19

scientific article

Increased Levels of Interferon-Inducible Protein 10 (IP-10) in 22q11.2 Deletion Syndrome

scientific article published on 27 December 2015

Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19

scientific article

Increased interleukin‐1β levels are associated with left ventricular hypertrophy and remodelling following acute ST segment elevation myocardial infarction treated by primary percutaneous coronary intervention ⬇️

scientific article published on February 26, 2012

Increased plasma levels of the terminal complement complex in patients with evidence of complement activation.

scientific article published in January 1985

Increased systemic activation of neutrophils but not complement in preeclampsia

scientific article published on 01 March 2001

Increased systemic and local interleukin 9 levels in patients with carotid and coronary atherosclerosis

scientific article

Inflammatory Response After Laparoscopic Versus Open Resection of Colorectal Liver Metastases: Data From the Oslo-CoMet Trial

scientific article

Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: results of a 5-year follow-up cohort study

scholarly article by William W Siljan et al published February 2019 in ERJ open research

Inflammatory markers sampled by microdialysis catheters distinguish rejection from ischemia in liver grafts

scientific article published on 26 September 2012

Inflammatory response and re-stenosis after percutaneous coronary intervention in heart transplant recipients and patients with native atherosclerosis

scientific article published on 01 August 2005

Inflammatory response induced by candidate biomaterials of an implantable microfabricated sensor

scientific article published on 15 February 2012

Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis

scientific article published on 24 July 2003

Inhibition of Complement-Mediated Red Cell Lysis by Immunoglobulins is Dependent on the IG Isotype and its Cl Binding Properties

scientific article published on 01 May 1995

Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis

scientific article

Inhibition of complement and CD14 attenuates the Escherichia coli-induced inflammatory response in porcine whole blood

scientific article published on December 2008

Inhibition of platelet aggregation by the GPIIb/IIIa antagonist reopro does not significantly prolong xenograft survival in an ex vivo model

scientific article published on 01 January 1999

Innate immune responses to danger signals in systemic inflammatory response syndrome and sepsis

scientific article published on June 2009

Interactions of histidine-rich glycoprotein with immunoglobulins and proteins of the complement system

scientific article

Interleukin-6 may predict survival in extracorporeal membrane oxygenation treatment

scientific article published in May 2008

Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction

scientific article published on 29 June 2018

Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease

scientific article published on 05 February 2020

Intestinal inflammatory profile shows increase in a diversity of biomarkers in irritable bowel syndrome

scientific article published on 24 April 2020

Intrathecal complement activation in neurological diseases evaluated by analysis of the terminal complement complex

scientific article published on 01 March 1987

Intrathecal immune response in neonatal Flavobacterium meningosepticum meningitis

scientific article published on 01 January 1995

Iron oxide nanoparticles enhance Toll-like receptor-induced cytokines in a particle size- and actin-dependent manner in human blood

scientific article published on 07 August 2018

Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model

scientific article

Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood

scientific article published on 25 July 2019

LDL apheresis activates the complement system and the cytokine network, whereas PCSK9 inhibition with evolocumab induces no inflammatory response

scientific article published on 13 September 2016

LDL apheresis and inflammation--implications for atherosclerosis

scientific article published on September 2012

Latex gloves as a cause of inflammation and eczema

scientific article published in June 1990

Letter to editor

scientific article published on 01 May 2013

Leucocyte filtration during cardiopulmonary bypass hardly changed leucocyte counts and did not influence myeloperoxidase, complement, cytokines or platelets

scientific article published on 01 November 1998

Leucocyte filtration during cardiopulmonary reperfusion in coronary artery bypass surgery

scientific article published on 01 March 1999

Low Levels of Immunoglobulins and Mannose-Binding Lectin Are Not Associated With Etiology, Severity, or Outcome in Community-Acquired Pneumonia

scientific article published on 5 January 2018

Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients

scientific article

Low levels of vitronectin and clusterin in acute meningococcal disease are closely associated with formation of the terminal-complement complex and the vitronectin-thrombin-antithrombin complex.

scientific article

Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischaemia, and rejection after human heart transplantation

scientific article published on 08 April 2005

Mannose binding lectin and soluble Toll-like receptor 2 in heart failure following acute myocardial infarction

scientific article published on 01 October 2006

Mannose-binding lectin in HIV infection: relation to disease progression and highly active antiretroviral therapy

scientific article published in April 2003

Mannose-binding lectin is a critical factor in systemic complement activation during meningococcal septic shock

scientific article published on November 2009

Massive Organ Inflammation in Experimental and in Clinical Meningococcal Septic Shock

scientific article published on November 2015

Measurement of complement activation

scientific article

Mechanism of complement activation and its role in the inflammatory response after thoracoabdominal aortic aneurysm repair

scientific article published on 4 August 2003

Mechanisms of complement activation and effects of C1-inhibitor on the meconium-induced inflammatory reaction in human cord blood

scientific article

Meconium Is a Potent Activator of Complement in Human Serum and in Piglets

article published in 2004

Meconium aspiration syndrome induces complement-associated systemic inflammatory response in newborn piglets.

scientific article published in March 2005

Meconium aspiration syndrome: possible pathophysiological mechanisms and future potential therapies

scientific article published on January 2015

Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner

scientific article

Methylprednisolone in High Doses Gives Different Effects on the Early and the Late Part of Complement

scientific article published on 01 January 1990

Microdialysis for monitoring inflammation: efficient recovery of cytokines and anaphylotoxins provided optimal catheter pore size and fluid velocity conditions

scientific article published on September 2006

Microdialysis monitoring of liver grafts by metabolic parameters, cytokine production, and complement activation

scientific article

Microparticle-associated tissue factor activity is reduced by inhibition of the complement protein 5 in Neisseria meningitidis-exposed whole blood

scientific article published on 19 September 2013

Modern complement analysis

scientific article published on November 2003

Modest release of adipsin/factor D by liposuction when using the superwet or tumescent technique

scientific article published on 01 May 1997

Modulation of fluid-phase complement activation inhibits hyperacute rejection in a porcine-to-human xenograft model

article

Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection

scientific article published on 01 December 2005

Monoclonal antibodies recognizing a neoantigen of poly(C9) detect the human terminal complement complex in tissue and plasma

scientific article

Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease

scientific article published on June 2014

Multiorgan procurement increases systemic inflammation in brain dead donors ⬇️

scientific article published on June 27, 2013

NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies

scientific article published on 01 January 2020

Neisseria meningitidis and Escherichia coli are protected from leukocyte phagocytosis by binding to erythrocyte complement receptor 1 in human blood

scientific article

Neutrophil gelatinase-associated lipocalin: a biomarker in COPD.

scientific article published on 21 May 2010

New biomarkers in an acute model of live Escherichia coli-induced sepsis in pigs

scientific article published on 6 May 2008

Occupational exposure to bacterial single cell protein induces inflammation in lung and blood

scientific article published on 01 July 2009

Off-pump cardiac surgery abolishes complement activation

scientific article published in July 2007

Organ inflammation in porcine Escherichia coli sepsis is markedly attenuated by combined inhibition of C5 and CD14.

scientific article

Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans

scientific article

Pathway-specific complement activity in pigs evaluated with a human functional complement assay

scientific article published on 27 March 2009

Patient tolerance regarding different low-density lipoprotein apheresis columns: Frequent minor side effects and high patient satisfaction ⬇️

scientific article published on November 18, 2010

Patients with depression display cytokine levels in serum and cerebrospinal fluid similar to patients with diffuse neurological symptoms without a defined diagnosis

scientific article published on 13 April 2016

Perfusion temperature, thyroid hormones and inflammation during pediatric cardiac surgery

scientific article published on 12 October 2009

Perioperative Infusion of Glucagon-Like Peptide-1 Prevents Insulin Resistance After Surgical Trauma in Female Pigs

scientific article published on 01 December 2019

Persistent complement activation in submucosal blood vessels of active inflammatory bowel disease: immunohistochemical evidence

scientific article published on 01 July 1989

Persisting thrombin activity in elderly patients with atrial fibrillation on oral anticoagulation is decreased by anti-inflammatory therapy with intensive cholesterol-lowering treatment ⬇️

scientific article published on May 20, 2011

Perspectives on complement in xenotransplantation

scientific article

Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14

scientific article published on 15 May 2019

Pig endogenous retrovirus--a threat to clinical xenotransplantation?

scientific article

Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts

scientific article published on October 2016

Plasma Levels of Marine n-3 Fatty Acids Are Inversely Correlated With Proinflammatory Markers sTNFR1 and IL-6 in Renal Transplant Recipients.

scientific article published on 9 November 2016

Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases

scientific article

Plasma cytokine expression in adolescent chronic fatigue syndrome

scientific article published on 31 December 2014

Plasma exchange in myasthenia gravis: changes in serum complement and immunoglobulins

scientific article published on 01 September 1988

Plasma levels of mannose-binding lectin and future risk of venous thromboembolism

scientific article published on 01 July 2019

Plasma n-6 Polyunsaturated Fatty Acid Levels and Survival in Renal Transplantation

scientific article published on 24 April 2018

Platelet compatibility of an artificial surface modified with functionally active heparin

scientific article published on 01 September 1999

Platelet-activating factor and kinin-dependent vascular leakage as a novel functional activity of the soluble terminal complement complex

scientific article

Platelets and vitronectin: immunocytochemical localization and platelet interaction with exogenously added vitronectin

scientific article published on 01 January 1992

Polyvalent immunoglobulin significantly attenuated the formation of IL-1β in Escherichia coli-induced sepsis in pigs ⬇️

scientific article published on August 9, 2012

Post challenge inhibition of C3 and CD14 attenuates Escherichia coli-induced inflammation in human whole blood

scientific article

Post-hypoxic hypothermia is protective in human NT2-N neurons regardless of oxygen concentration during reoxygenation

scientific article

Pre-neutralization of C5a-mediated effects by the monoclonal antibody 137-26 reacting with the C5a moiety of native C5 without preventing C5 cleavage

scientific article published in August 2003

Prediction of inflammatory responses induced by biomaterials in contact with human blood using protein fingerprint from plasma

scientific article

Preface. 15th European Meeting on Complement in Human Disease 2015, Uppsala, Sweden

scientific article published on 29 April 2015

Primary complement C5 deficiencies - molecular characterization and clinical review of two families

scientific article published on 14 May 2013

Prolongation of ex vivo–perfused pig xenograft survival by the complement inhibitor compstatin

scientific article published on 01 February 1999

Properdin binding to complement activating surfaces depends on initial C3b deposition

scientific article published on 09 January 2017

Pseudo-anaphylaxis to Polyethylene Glycol (PEG)-Coated Liposomes: Roles of Anti-PEG IgM and Complement Activation in a Porcine Model of Human Infusion Reactions

scientific article published on 06 August 2019

Quantification in Enzyme-Linked Immunosorbent Assay of a C3 Neoepitope Expressed on Activated Human Complement Factor C3

scientific article published on 01 March 1988

Quantification of Non-Activated (Native) Complement Component C9 Synthesized by Alveolar Macrophages from Patients with Sarcoidosis

scientific article published on 01 May 1990

Quantification of the terminal complement complex in human plasma by an enzyme-linked immunosorbent assay based on monoclonal antibodies against a neoantigen of the complex

scientific article published on 01 August 1985

Quantitation of vitronectin and clusterin. Pitfalls and solutions in enzyme immunoassays for adhesive proteins

scientific article published on 01 March 1993

Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood

scientific article published on 9 November 2015

Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation

scientific article published on 29 May 2015

Recurrent meningococcal sepsis in a presumptive immunocompetent host shown to be complement C5 deficient-a case report ⬇️

scientific article published on April 8, 2011

Reduced complement activation with heparin-coated oxygenator and tubings in coronary bypass operations ⬇️

scientific article published on April 1, 1992

Reduced complement and granulocyte activation with heparin-coated cardiopulmonary bypass

scientific article published on 01 August 1994

Reduced inflammatory response by transcatheter, as compared to surgical aortic valve replacement

scientific article published on 12 December 2017

Regulation of complement

scientific article published on February 1988

Release of interleukin 6 and activation of complement during and after paediatric cardiopulmonary bypass. Effect of autotransfusion of shed mediastinal blood and ultrafiltration

scientific article

Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine response ex vivo

scientific article

Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency

scientific article published in Scientific Reports

Role of complement and CD14 in meconium-induced cytokine formation

scientific article

Role of complement in xenotransplantation

scientific article published on 01 January 2002

Role of granulocytes and monocytes in the polyvinyl chloride-induced synthesis of interleukin 8, monocyte chemoattractant protein 1, and leukotriene B4

scientific article published on 01 August 2005

Roller and centrifugal pumps compared in vitro with regard to haemolysis, granulocyte and complement activation

scientific article published on 01 March 1994

S protein binds to serum-treated agarose beads independently of complement activation and the formation of the terminal complement complex on the beads

scientific article published in March 1990

S-protein is synthesized by human monocytes and macrophages in vitro

scientific article published on 01 January 1989

Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: a dysregulation with potential inflammatory effects

scientific article published on 10 November 2019

Selective inhibition of TNF-alpha or IL-1 beta does not affect E. coli-induced inflammation in human whole blood

scientific article published on 23 March 2010

Selective whole blood lipoprotein apheresis to prevent pancreatitis in drug refractory hypertriglyceridemia

scientific article published on 06 September 2010

Sensitive, reliable and easy-performed laboratory monitoring of eculizumab therapy in atypical hemolytic uremic syndrome

scientific article

Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model

scientific article published on 27 June 2019

Serum brain-derived neurotrophic factor levels in relation to comorbid depression and cytokine levels in Nepalese men with alcohol-use disorders

scientific article

Serum clusterin and vitronectin in alcoholic cirrhosis

scientific article

Serum cytokines and chronic fatigue in adults surviving after childhood leukemia and lymphoma

scientific article published on 17 January 2013

Severe human septic shock involves more than tumor necrosis factor

scientific article published on January 1991

Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction

scientific article published on 28 May 2018

Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement

scientific article published on 10 September 2020

Soluble toll-like receptor 2 in HIV infection: association with disease progression

scientific article published on 01 December 2004

Specific allergen immunotherapy: effect on IgE, IgG4 and chemokines in patients with allergic rhinitis

scientific article

Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation

scientific article published on 30 June 2008

Staphylococcus aureus-induced Complement Activation Promotes Tissue Factor-mediated Coagulation

scientific article published on 13 February 2018

Staphylococcus epidermidis biofilms induce lower complement activation in neonates as compared with adults

scientific article published on 11 December 2012

Staphylococcus epidermidis polysaccharide intercellular adhesin activates complement

scientific article published on 01 November 2011

Statin drugs do not affect serum complement activation in vitro

scientific article published in July 2004

Strategies of therapeutic complement inhibition

scientific article

Studies on the Dose Dependence of Endotoxin-Induced in vitro Activation of the Complement System

scientific article published on 01 January 1989

Study findings challenge the content validity of the Canadian Consensus Criteria for adolescent chronic fatigue syndrome

scientific article published on 23 March 2015

Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis

scientific article

Surface epithelium related activation of complement differs in Crohn's disease and ulcerative colitis

scientific article

Syndecan-1 plasma levels during coronary artery bypass surgery with and without cardiopulmonary bypass

scientific article published in May 2008

Synthesis of C3, C5, C6, C7, C8, and C9 by human fibroblasts

scientific article published on November 1990

Synthesis of Complement by Alveolar Macrophages from Patients with Sarcoidosis

scientific article published on 01 January 1990

Synthesis of Soluble C3 and C9 Neoepitopes by Human Alveolar Macrophages in Vitro

scientific article published on 01 October 1988

Systemic CD14 Inhibition Attenuates Organ Inflammation in Porcine Escherichia coli Sepsis ⬇️

scientific article published on June 17, 2013

Systemic Inflammation Persists the First Year After Mild Traumatic Brain Injury: Results from the Prospective Trondheim Mild TBI Study

scientific article published on 24 April 2020

Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis ⬇️

scientific article published on June 25, 2012

Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients

scientific article published on 17 September 2020

Systemic inflammation in acute intermittent porphyria: a case-control study

scientific article published on 8 November 2016

Systemic inflammatory markers in COPD: results from the Bergen COPD Cohort Study

scientific article published on 30 July 2009

Systemic mannose-binding lectin is not associated with Chronic Obstructive Pulmonary Disease

scientific article published on 01 February 2010

Systemic meningococcal disease: a model infection to study acute endotoxinemia in man

scientific article published on 01 January 1988

TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-β Production via a TAK1-IKKβ-IRF5 Signaling Pathway

scientific article published on 17 June 2015

TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria

scientific article published on 21 February 2020

Terminal complement complex (TCC) and S-protein (vitronectin) on follicular dendritic cells in human lymphoid tissues

scientific article published on 01 October 1988

Terminal complement pathway activation and low lysis inhibitors in rheumatoid arthritis synovial fluid

scientific article published on 01 January 1995

The B chain, but not the A chain, of Ricinus communis activates human complement

scientific article published on 01 November 1993

The Fluid-phase SC5b-9 Terminal Complement Complex Binds to the GPIIb/IIIa Complex of Thrombin-stimulated Human Blood Platelets Inhibiting Platelet Aggregation

scientific article published on 01 January 1995

The Membrane Glycoprotein IIb/IIIa Complex Mediates Deposition of Thrombin-stimulated Blood Platelets on Polystyrene Plastic Under Static Conditions

scientific article published on January 1, 1994

The Palliative Radiotherapy and Inflammation Study (PRAIS) - protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain

The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes

scientific article

The Role of Complement in Liver Injury, Regeneration, and Transplantation

scientific article published on 15 July 2019

The alternative complement pathway is dysregulated in patients with chronic heart failure

scientific article published on 14 February 2017

The alternative complement pathway revisited

scientific article published on 15 April 2008

The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load

scientific article published on 23 April 2015

The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent

scientific article published on October 2008

The chemokine network in relation to infarct size and left ventricular remodeling following acute myocardial infarction

scientific article published on 16 September 2009

The complement component C5 is not responsible for the alternative pathway activity in rabbit erythrocyte hemolytic assays during eculizumab treatment

scientific article published on 24 March 2020

The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis

scientific article

The complement system in trauma-related and ischemic tissue damage: a brief review.

scientific article published on October 1994

The down-stream effects of mannan-induced lectin complement pathway activation depend quantitatively on alternative pathway amplification

scientific article published on 01 October 2009

The effect of exercise on serum levels of interleukin-18 and components of the metabolic syndrome

scientific article published in December 2009

The effects of selective complement and CD14 inhibition on the E. coli-induced tissue factor mRNA upregulation, monocyte tissue factor expression, and tissue factor functional activity in human whole blood

scientific article published in January 2013

The excessive complement activation in fulminant meningococcal septicemia is predominantly caused by alternative pathway activation

scientific article published on 01 March 1996

The induction of cytokines by polycation containing microspheres by a complement dependent mechanism

scientific article

The inflammatory response following treatment of abdominal aortic aneurysms: a comparison between open surgery and endovascular repair

scientific article published on 01 May 2000

The key roles of complement and tissue factor in Escherichia coli-induced coagulation in human whole blood

scientific article published on 9 June 2015

The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation

scientific article published on 01 December 2004

The role of bradykinin and the effect of the bradykinin receptor antagonist icatibant in porcine sepsis.

scientific article

The role of complement C3 opsonization, C5a receptor, and CD14 in E. coli-induced up-regulation of granulocyte and monocyte CD11b/CD18 (CR3), phagocytosis, and oxidative burst in human whole blood

scientific article published on 27 March 2007

The role of complement in biomaterial-induced inflammation

scientific article published on 14 August 2006

The role of complement in meconium aspiration syndrome

scientific article published on December 2008

The role of properdin in zymosan- and Escherichia coli-induced complement activation

scientific article published on 30 July 2012

The significance of heparin-coated veno-venous bypass circuits in liver transplantation

scientific article published on 01 January 2002

The soluble terminal complement complex (SC5b-9) up-regulates osteoprotegerin expression and release by endothelial cells: implications in rheumatoid arthritis

scientific article published on 23 January 2009

The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model

scientific article published on 26 April 2019

The terminal complement complex in sera deficient in the eighth component of complement (C8)

scientific article published on 01 September 1986

The use of flow cytometry to detect the biosynthesis of complement components

scientific article published on July 1991

Therapeutic complement inhibition – from experimental to clinical medicine

scientific article

Three different LDL apheresis columns efficiently and equally reduce lipoprotein(a) concentrations in patients with familial hypercholesterolemia and small apolipoprotein(a) particles

scientific article published on 27 December 2011

Thrombin Differentially Modulates the Acute Inflammatory Response to <i>Escherichia coli</i> and <i>Staphylococcus aureus</i> in Human Whole Blood

scientific article published in 2022

Time for new concepts about measurement of complement activation by cardiopulmonary bypass?

scientific article published on 01 October 1992

Toward an injectable continuous osmotic glucose sensor

scientific article

Transforming growth factor beta (TGF-β) in adolescent chronic fatigue syndrome

scientific article published on 4 December 2017

Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study.

scientific article published on 19 January 2018

Tubing loops as a model for cardiopulmonary bypass circuits: both the biomaterial and the blood-gas phase interfaces induce complement activation in an in vitro model

scientific article published on 01 July 1996

Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study

scientific article published on 23 July 2019

Ultrafiltration after cardiopulmonary bypass in children: effects on hemodynamics, cytokines and complement

scientific article

Universal fresh frozen plasma (Uniplas): a safe product in open-heart surgery

scientific article published on 04 September 2003

Veno-venous bypass in liver transplantation: heparin-coated perfusion circuits reduce the activation of humoral defense systems in an in vitro model

scientific article published on 01 July 2001

Vitronectin inhibits blood platelet aggregation

scientific article published on January 1, 1993

Xenotransplantation: how to overcome the complement obstacle?

scientific article

[A programme for boosting medical research in North Norway, 1992-2001]

scientific article published on 01 February 2005

[Angioedema associated with ACE inhibitors]

scientific article published on 01 March 1994

[Reduced blood utilization in hip arthroplasty. Introduction of a blood preservation program]

scientific article published on 01 January 1996

[Transplantation from animal to man]

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