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List of works by Jung-Chien Cheng

ALK2/ALK3-BMPR2/ACVR2A Mediate BMP2-Induced Downregulation of Pentraxin 3 Expression in Human Granulosa-Lutein Cells.

scientific article

APELA promotes tumour growth and cell migration in ovarian cancer in a p53-dependent manner.

scientific article published on 24 October 2017

Activin A promotes ovarian cancer cell migration by suppressing E-cadherin expression

scientific article published on 20 June 2019

Activin A upregulates PTGS2 expression and increases PGE2 production in human granulosa-lutein cells.

scientific article published on 13 September 2016

Activin A, B and AB decrease progesterone production by down-regulating StAR in human granulosa cells.

scientific article

Activin A, B, and AB increase human trophoblast cell invasion by up-regulating N-cadherin.

scientific article

Activin A-induced increase in LOX activity in human granulosa-lutein cells is mediated by CTGF.

scientific article

Activin B induces human endometrial cancer cell adhesion, migration and invasion by up-regulating integrin β3 via SMAD2/3 signaling

scientific article published on 28 August 2015

Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling.

scientific article published on 19 May 2016

Amphiregulin induces human ovarian cancer cell invasion by down-regulating E-cadherin expression

scientific article published on 23 September 2014

BMP15 suppresses progesterone production by down-regulating StAR via ALK3 in human granulosa cells.

scientific article

Betacellulin enhances ovarian cancer cell migration by up-regulating Connexin43 via MEK-ERK signaling

scientific article published on 22 October 2019

Betacellulin induces Slug-mediated down-regulation of E-cadherin and cell migration in ovarian cancer cells.

scientific article published on 22 February 2016

CD40 ligand induces RIP1-dependent, necroptosis-like cell death in low-grade serous but not serous borderline ovarian tumor cells.

scientific article

COX2 and PGE2 mediate EGF-induced E-cadherin-independent human ovarian cancer cell invasion.

scientific article

Connective tissue growth factor mediates TGF-β1-induced low-grade serous ovarian tumor cell apoptosis

scientific article

Connective tissue growth factor mediates growth differentiation factor 8-induced increase of lysyl oxidase activity in human granulosa-lutein cells.

scientific article published on 5 July 2016

EGF promotes human trophoblast cell invasion by downregulating CTGF expression via PI3K/AKT signaling

scientific article published in 2023

EGF-Induced Connexin43 Negatively Regulates Cell Proliferation in Human Ovarian Cancer.

scientific article published on 29 May 2015

EGF-induced EMT and invasiveness in serous borderline ovarian tumor cells: a possible step in the transition to low-grade serous carcinoma cells?

scientific article

EGF-like growth factors induce COX-2-derived PGE2 production through ERK1/2 in human granulosa cells.

scientific article published on 3 October 2013

Effects of growth differentiation factor 8 on steroidogenesis in human granulosa-lutein cells

scientific article published on 19 November 2015

Effects of recombinant activins on steroidogenesis in human granulosa-lutein cells.

scientific article published on 25 July 2014

Egr-1 mediates epidermal growth factor-induced downregulation of E-cadherin expression via Slug in human ovarian cancer cells.

scientific article

EpCAM is up-regulated by EGF via ERK1/2 signaling and suppresses human epithelial ovarian cancer cell migration.

scientific article

FOXL2-induced follistatin attenuates activin A-stimulated cell proliferation in human granulosa cell tumors.

scientific article published on 8 December 2013

Gonadotropin-releasing hormone and ovarian cancer: a functional and mechanistic overview.

scientific article

Gonadotropin-releasing hormone type II induces apoptosis of human endometrial cancer cells by activating GADD45alpha.

scientific article published on 14 April 2009

Growth Differentiation Factor-8 Decreases StAR Expression Through ALK5-Mediated Smad3 and ERK1/2 Signaling Pathways in Luteinized Human Granulosa Cells

scientific article published on 22 September 2015

Growth differentiation factor 8 down-regulates pentraxin 3 in human granulosa cells

scientific article

Growth differentiation factor 8 induces SKOV3 ovarian cancer cell migration and E-cadherin down-regulation.

scientific article published on 29 July 2016

Growth differentiation factor 8 suppresses cell proliferation by up-regulating CTGF expression in human granulosa cells.

scientific article published on 11 November 2015

Growth hormone-releasing hormone antagonist induces apoptosis of human endometrial cancer cells through PKCδ-mediated activation of p53/p21.

scientific article published on 13 July 2010

HER2 mediates epidermal growth factor-induced down-regulation of E-cadherin in human ovarian cancer cells.

scientific article published on 29 March 2013

Hepatocyte Nuclear Factor 4-Alpha Is Essential for the Active Epigenetic State at Enhancers in Mouse Liver

scientific article published on 15 May 2019

Homeobox A7 stimulates breast cancer cell proliferation by up-regulating estrogen receptor-alpha

scientific article published on 04 October 2013

Hydrogen peroxide mediates EGF-induced down-regulation of E-cadherin expression via p38 MAPK and snail in human ovarian cancer cells.

scientific article

Hypoxia-inducible factor 1 alpha mediates epidermal growth factor-induced down-regulation of E-cadherin expression and cell invasion in human ovarian cancer cells.

scientific article

Inhibition of p53 induces invasion of serous borderline ovarian tumor cells by accentuating PI3K/Akt-mediated suppression of E-cadherin ⬇️

scientific article published on October 25, 2010

Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells ⬇️

scientific article published on April 11, 2011

Lapatinib Inhibits Amphiregulin-induced BeWo Choriocarcinoma Cell Proliferation by Reducing ERK1/2 and AKT Signaling Pathways

scientific article published on 01 May 2019

Lithium Chloride Increases COX-2 Expression and PGE2 Production in a Human Granulosa-Lutein SVOG Cell Line Via a GSK-3β/β-Catenin Signaling Pathway

scientific article

Lithium chloride inhibits StAR and progesterone production through GSK-3β and ERK1/2 signaling pathways in human granulosa-lutein cells.

scientific article published on 31 August 2017

Loss of Sprouty2 in human high-grade serous ovarian carcinomas promotes EGF-induced E-cadherin down-regulation and cell invasion

scientific article published on 20 December 2014

Melatonin stimulates aromatase expression and estradiol production in human granulosa-lutein cells: relevance for high serum estradiol levels in patients with ovarian hyperstimulation syndrome

scientific article published on 27 August 2020

NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling

scientific article published in 2023

Nitric oxide and cGMP induce COX-2 expression and PGE2 production in human granulosa cells through CREB signaling pathway.

scientific article

Novel dihydroartemisinin dimer containing nitrogen atoms inhibits growth of endometrial cancer cells and may correlate with increasing intracellular peroxynitrite

scientific article published on 29 October 2019

Oocyte-derived BMP15 but not GDF9 down-regulates connexin43 expression and decreases gap junction intercellular communication activity in immortalized human granulosa cells

scientific article published on 10 January 2014

Overexpression of wild-type but not C134W mutant FOXL2 enhances GnRH-induced cell apoptosis by increasing GnRH receptor expression in human granulosa cell tumors.

scientific article

Recombinant BMP4 and BMP7 downregulate pentraxin 3 in human granulosa cells

scientific article published on 16 December 2014

Recombinant BMP4 and BMP7 increase activin A production by up-regulating inhibin βA subunit and furin expression in human granulosa-lutein cells.

scientific article

S1P Stimulates Proliferation by Upregulating CTGF Expression through S1PR2-Mediated YAP Activation

scientific article published on 14 June 2018

SMAD1/5 mediates bone morphogenetic protein 2-induced up-regulation of BAMBI expression in human granulosa-lutein cells

scientific article published on 31 May 2017

Spectrofluorometric analysis of length-dependent conformational changes in cardiac troponin C.

scientific article published in January 2002

Sphingosine-1-phosphate induces COX-2 expression and PGE2 production in human granulosa cells through a S1P1/3-mediated YAP signaling.

scientific article published on 16 March 2016

Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.

scientific article

Sprouty4 mediates amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.

scientific article published on 14 January 2016

TGF-beta induces serous borderline ovarian tumor cell invasion by activating EMT but triggers apoptosis in low-grade serous ovarian carcinoma cells.

scientific article

TGF-β1 Inhibits Human Trophoblast Cell Invasion by Upregulating Connective Tissue Growth Factor Expression.

scientific article published in October 2017

TGF-β1 Up-Regulates Connective Tissue Growth Factor Expression in Human Granulosa Cells through Smad and ERK1/2 Signaling Pathways.

scientific article published on 8 May 2015

TGF-β1 downregulates StAR expression and decreases progesterone production through Smad3 and ERK1/2 signaling pathways in human granulosa cells

scientific article published on 20 August 2014

TGF-β1 induces COX-2 expression and PGE2 production in human granulosa cells through Smad signaling pathways.

scientific article published on 8 April 2014

TGF-β1 inhibits human trophoblast cell invasion by upregulating cyclooxygenase-2

scientific article published on 30 June 2018

TGF-β1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways.

scientific article published on 16 August 2016

TGF-β1 up-regulates cadherin-11 expression through Snail: A potential mechanism for human trophoblast cell differentiation.

scientific article published on 18 December 2017

TGF-β1 up-regulates connexin43 expression: a potential mechanism for human trophoblast cell differentiation.

scientific article

TGFβ1 induces endometrial cancer cell adhesion and migration by up-regulating integrin αvβ3 via SMAD-independent MEK-ERK1/2 signaling

scientific article published on 21 March 2017

Theca-Derived BMP4 and BMP7 Down-Regulate Connexin43 Expression and Decrease Gap Junction Intercellular Communication Activity in Immortalized Human Granulosa Cells ⬇️

scientific article published on February 5, 2013

Transforming growth factor-α induces human ovarian cancer cell invasion by down-regulating E-cadherin in a Snail-independent manner

scientific article

Transforming growth factor-β stimulates human ovarian cancer cell migration by up-regulating connexin43 expression via Smad2/3 signaling

scientific article published on 14 July 2015

Transforming growth factor-β1 increases lysyl oxidase expression by downregulating MIR29A in human granulosa lutein cells.

scientific article

Transforming growth factor-β1 inhibits trophoblast cell invasion by inducing Snail-mediated down-regulation of vascular endothelial-cadherin protein.

scientific article published on 08 October 2013

Transforming growth factor-β1 up-regulates connexin43 expression in human granulosa cells

scientific article

Type I collagen down-regulates E-cadherin expression by increasing PI3KCA in cancer cells ⬇️

scientific article published on March 4, 2011

WNK1 mediates amphiregulin-induced MMP9 expression and cell invasion in human extravillous trophoblast cells

scientific article published in 2023

Wild-type p53 attenuates cancer cell motility by inducing growth differentiation factor-15 expression.

scientific article published on 17 May 2011

YAP transcriptionally regulates ErbB2 to promote liver cell proliferation

scientific article published on 17 July 2018

hCG-induced Sprouty2 mediates amphiregulin-stimulated COX-2/PGE2 up-regulation in human granulosa cells: a potential mechanism for the OHSS.

scientific article published on 19 August 2016

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