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List of works by František Štaud

Alteration of Methotrexate Biliary and Renal Elimination during Extrahepatic and Intrahepatic Cholestasis in Rats

scientific article published on 01 December 2009

Amiodarone modulates pharmacokinetics of low-dose methotrexate in rats.

scientific article published in July 2008

Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression.

scientific article published on 12 November 2007

Boldine enhances bile production in rats via osmotic and farnesoid X receptor dependent mechanisms

scientific article published on 12 March 2015

Breast cancer resistance protein (BCRP/ABCG2).

scientific article

Corticosterone transfer and metabolism in the dually perfused rat placenta: effect of 11beta-hydroxysteroid dehydrogenase type 2.

scientific article

Dexamethasone and betamethasone administration during pregnancy affects expression and function of 11 beta-hydroxysteroid dehydrogenase type 2 in the rat placenta

scientific journal article

Dinaciclib, a cyclin-dependent kinase inhibitor, is a substrate of human ABCB1 and ABCG2 and an inhibitor of human ABCC1 in vitro.

scientific article published on 20 August 2015

Disposition of radioactivity after injection of liver-targeted proteins labeled with 111In or 125I. Effect of labeling on distribution and excretion of radioactivity in rats

scientific article published on 01 June 1999

Efavirenz reduces renal excretion of lamivudine in rats by inhibiting organic cation transporters (OCT, Oct) and multidrug and toxin extrusion proteins (MATE, Mate)

scientific article published in PLoS ONE

Effect of ABCG2 on cytotoxicity of platinum drugs: interference of EGFP.

scientific article published on 9 September 2008

Effect of drug efflux transporters on placental transport of antiretroviral agent abacavir.

scientific article

Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters.

scientific article

Equilibrative Nucleoside Transporter 1 (ENT1, ) Facilitates Transfer of the Antiretroviral Drug Abacavir across the Placenta

scientific article published on 10 August 2018

Etravirine inhibits ABCG2 drug transporter and affects transplacental passage of tenofovir disoproxil fumarate.

scientific article

Examination of Glucocorticoid receptor alpha-mediated transcriptional regulation of P-glycoprotein, CYP3A4, and CYP2C9 genes in placental trophoblast cell lines.

scientific article

Examination of the functional activity of P-glycoprotein in the rat placental barrier using rhodamine 123

scientific journal article

Expression and functional activity of breast cancer resistance protein (BCRP, ABCG2) transporter in the human choriocarcinoma cell line BeWo.

scientific article published on January 2006

IL-1 receptor blockade alleviates endotoxin-mediated impairment of renal drug excretory functions in rats

scientific article published on 10 December 2014

Influence of P-glycoprotein on the transplacental passage of cyclosporine.

scientific article published in October 2001

Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice

scientific article published on 01 January 2004

Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance

scientific article published on 08 May 2019

Interactions of cyclin-dependent kinase inhibitors AT-7519, flavopiridol and SNS-032 with ABCB1, ABCG2 and ABCC1 transporters and their potential to overcome multidrug resistance in vitro.

scientific article published on 19 May 2015

Interactions of tenofovir and tenofovir disoproxil fumarate with drug efflux transporters ABCB1, ABCG2, and ABCC2; role in transport across the placenta.

scientific article published on January 2014

Lack of interactions between breast cancer resistance protein (bcrp/abcg2) and selected antiepileptic agents.

scientific article published in March 2006

Liver uptake and hepato-biliary transfer of galactosylated proteins in rats are determined by the extent of galactosylation

scientific article published on 01 April 1999

Long-term administration of tenofovir or emtricitabine to pregnant rats; effect on Abcb1a, Abcb1b and Abcg2 expression in the placenta and in maternal and fetal organs.

scientific article published on 4 January 2016

MDR1 and BCRP Transporter-Mediated Drug-Drug Interaction between Rilpivirine and Abacavir and Effect on Intestinal Absorption.

scientific article

Molecular determinants in the transport of a bile acid-derived diagnostic agent in tumoral and nontumoral cell lines of human liver.

scientific article published on 8 August 2006

Multidrug and toxin extrusion proteins (MATE/SLC47); role in pharmacokinetics.

scientific article published on 05 July 2013

Olomoucine II and purvalanol A inhibit ABCG2 transporter in vitro and in situ and synergistically potentiate cytostatic effect of mitoxantrone.

scientific article

Olomoucine II, but not purvalanol A, is transported by breast cancer resistance protein (ABCG2) and P-glycoprotein (ABCB1)

scientific article (publication date: 2013)

Organic Cation Transporter 3 (OCT3/SLC22A3) and Multidrug and Toxin Extrusion 1 (MATE1/SLC47A1) Transporter in the Placenta and Fetal Tissues: Expression Profile and Fetus Protective Role at Different Stages of Gestation1

article

P-glycoprotein in the placenta: expression, localization, regulation and function.

scientific article

Pharmacotherapy in pregnancy; effect of ABC and SLC transporters on drug transport across the placenta and fetal drug exposure ⬇️

scientific article published on September 20, 2012

Placental passage of olomoucine II, but not purvalanol A, is affected by p-glycoprotein (ABCB1), breast cancer resistance protein (ABCG2) and multidrug resistance-associated proteins (ABCCs).

scientific article

Prenatal inflammation as a link between placental expression signature of tryptophan metabolism and preterm birth

scientific article published on 01 November 2021

Profiling of Tryptophan Metabolic Pathways in the Rat Fetoplacental Unit During Gestation

scientific article published on 14 October 2020

Purvalanol A, olomoucine II and roscovitine inhibit ABCB1 transporter and synergistically potentiate cytotoxic effects of daunorubicin in vitro

scientific article (publication date: 2013)

Reciprocal changes in maternal and fetal metabolism of corticosterone in rat during gestation

scientific journal article

Regulation of drug transporter expression and function in the placenta.

scientific article

Role of ABC and Solute Carrier Transporters in the Placental Transport of Lamivudine.

scientific article published on 11 July 2016

Role of ABCB1, ABCG2, ABCC2 and ABCC5 transporters in placental passage of zidovudine.

scientific article

Role of breast cancer resistance protein (Bcrp/Abcg2) in fetal protection during gestation in rat

scientific journal article

Salicylanilide acetates: synthesis and antibacterial evaluation.

scientific article published on January 2007

Synthesis and antimicrobial evaluation of new 2-substituted 5,7-di-tert-butylbenzoxazoles.

scientific article published on 19 June 2006

Synthesis of pH-sensitive amphotericin B-poly(ethylene glycol) conjugates and study of their controlled release in vitro

scientific article published on 03 April 2007

Tetratricopeptide repeat motifs in the world of bacterial pathogens: role in virulence mechanisms.

scientific article published on 21 December 2012

Transplacental pharmacokinetics of glyburide, rhodamine 123, and BODIPY FL prazosin: effect of drug efflux transporters and lipid solubility.

scientific article published on 24 September 2009

Up-regulation of renal Mdr1 and Mrp2 transporters during amiodarone pretreatment in rats.

scientific article published on 22 August 2009

Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.

scientific article published on 28 March 2007

Variation of drug kinetics in pregnancy.

scientific article published on June 2009

Zonation of multidrug resistance-associated protein 2 in rat liver after induction with dexamethasone

scientific journal article

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