Search filters

List of works by Marián Hajdúch

2-Deoxyglycoside Conjugates of Lupane Triterpenoids with High Cytotoxic Activity-Synthesis, Activity, and Pharmacokinetic Profile

scientific article published on 08 October 2019

2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity.

scientific article

2-phenylsubstituted-3-hydroxyquinolin-4(1H)-one-carboxamides: Structure-cytotoxic activity relationship study.

scientific article

4-arylazo-3,5-diamino-1H-pyrazole CDK inhibitors: SAR study, crystal structure in complex with CDK2, selectivity, and cellular effects

scientific article published on November 2006

6-(Het)aryl-7-deazapurine ribonucleosides as novel potent cytostatic agents

scientific article

68Ga-labelled desferrioxamine-B for bacterial infection imaging

scientific article published on 30 July 2020

7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action.

scientific article published on 27 January 2016

A Head-to-Head Analytical Comparison of Cobas 4800 HPV, PapilloCheck HPV Screening, and LMNX Genotyping Kit HPV GP for Detection of Human Papillomavirus DNA in Cervical and Cervicovaginal Swabs

scientific article published on 28 August 2018

A comparison of Direct sequencing, Pyrosequencing, High resolution melting analysis, TheraScreen DxS, and the K-ras StripAssay for detecting KRAS mutations in non small cell lung carcinomas

scientific article published on 20 September 2012

A duplication dup(4)(q28q35.2) de novo in a newborn

scientific article published on July 2006

A retrospective analysis of trastuzumab-based therapy in metastatic breast cancer patients at Masaryk Memorial Cancer Institute. Identification of predictive factors

scientific article published in January 2008

Acute lymphoblastic leukemia in a child with Leri-Weill syndrome and complete SHOX gene deletion: A Case Report

scientific article published on 21 February 2018

Affinity-based methods in drug-target discovery

scientific article published on 01 January 2015

Age-Dependent Progression in Lung Pathophysiology can be Prevented by Restoring Fatty Acid and Ceramide Imbalance in Cystic Fibrosis

scientific article published on 18 April 2020

Age-related changes in the lateral lipid distribution in a human lens described by mass spectrometry imaging

scientific article published on January 2015

Akt expression and compartmentalization in prediction of clinical outcome in HER2-positive metastatic breast cancer patients treated with trastuzumab

scientific article

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.

scientific article

AllerGen’s 8th research conference.

scientific article published on 8 December 2016

Amino-BODIPY as the ratiometric fluorescent sensor for monitoring drug release or "power supply" selector for molecular electronics

scientific article published on 13 August 2019

Analysis of prognostic significance of merkel cell polyomavirus in chronic lymphocytic leukemia

scientific article published on 11 February 2015

Analysis of state-specific phosphorylation of proteins by two-dimensional gel electrophoresis approach

scientific article published on 01 April 2003

Androgenetic alopecia and current methods of treatment.

scientific article

Anticancer activity of natural cytokinins: a structure-activity relationship study

scientific article published in June 2010

Application of proteomics in the search for novel proteins associated with the anti-cancer effect of the synthetic cyclin-dependent kinases inhibitor, bohemine.

scientific article

Assessing different thiazolidine and thiazole based compounds as antileishmanial scaffolds

scientific article published on 19 October 2020

Assessing opportunities for coordinated R&D in early cancer detection and management in Europe

scientific article published on 10 December 2016

Aurora kinase inhibitors: progress towards the clinic

scientific article published on 18 February 2012

Aurora kinases: structure, functions and their association with cancer.

scientific article published on June 2008

BCL2 is a predictive marker of adjuvant CMF regimen in triple-negative breast cancer patients.

scientific article published on 16 November 2011

BCL2 is an independent predictor of outcome in basal-like triple-negative breast cancers treated with adjuvant anthracycline-based chemotherapy

scientific article published on 24 January 2015

Batch immunoextraction method for efficient purification of aromatic cytokinins

scientific article

Bioavailability and structural study of 20-hydroxyecdysone complexes with cyclodextrins

scientific article published on 17 November 2018

Biodegradable system for drug delivery of hydrolytically labile azanucleoside drugs.

scientific article

Bioequivalence of two brands of citalopram 40 mg tablets after single oral administration to healthy volunteers.

scientific article published in June 2005

Biomarkers in Immunoglobulin Light Chain Amyloidosis.

scientific article

Bone marrow metastasis of malignant melanoma in childhood arising within a congenital melanocytic nevus.

scientific article

Bridging the translational innovation gap through good biomarker practice

scientific article published on 28 April 2017

Caffeine-hydrazones as anticancer agents with pronounced selectivity toward T-lymphoblastic leukaemia cells

scientific article published on 2 April 2015

Cancer Drug-Resistance and a Look at Specific Proteins: Rho GDP-Dissociation Inhibitor 2, Y-Box Binding Protein 1, and HSP70/90 Organizing Protein in Proteomics Clinical Application ⬇️

scientific article published on December 3, 2010

Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy.

scientific article

Cancer cell response to anthracyclines effects: mysteries of the hidden proteins associated with these drugs

scientific article published on 22 November 2012

Cannabidiol-induced activation of the metallothionein pathway impedes anticancer effects of disulfiram and its metabolite CuET

scientific article published on 26 October 2021

Cardiac amyloidosis: from clinical suspicion to morphological diagnosis

scientific article published on 12 February 2018

Cell-based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D, and xenograft models.

scientific article

Cellular effects of the microtubule-targeting agent peloruside A in hypoxia-conditioned colorectal carcinoma cells.

scientific article

Challenges in cancer research and multifaceted approaches for cancer biomarker quest.

scientific article published on 25 March 2009

Characterization of Pseudacyclins A−E, a Suite of Cyclic Peptides Produced byPseudallescheria boydii

scientific article published on 28 May 2010

Characterization of iron metabolism and erythropoiesis in erythrocyte membrane defects and thalassemia traits.

scientific article published on 27 October 2015

Clinical relevance of KRAS in human cancers

scientific article

Combination of prednisolone and low dosed dexamethasone exhibits greater in vitro antileukemic activity than equiactive dose of prednisolone and overcomes prednisolone drug resistance in acute childhood lymphoblastic leukemia

scientific article published on 31 October 2012

Comblike dendrimers containing Tn antigen modulate natural killing and induce the production of Tn specific antibodies

scientific article published on 01 October 2006

Comparison of 68Ga-labeled RGD mono- and multimers based on a clickable siderophore-based scaffold

scientific article published on 25 October 2019

Complex karyotypes in childhood acute lymphoblastic leukemia: cytogenetic and molecular cytogenetic study of 21 cases

scientific article published on 01 September 2003

Correction to "Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides"

scientific article published on 25 January 2019

Correlation of cytotoxic activity of betulinines and their hydroxy analogues.

scientific article published on October 2005

Cyclocondensation reaction of heterocyclic carbonyl compounds. Part XIII: synthesis and cytotoxic activity of some 3,7-diaryl-5-(3,4,5-trimethoxyphenyl)pyrazolo[4,3-e][1,2,4]triazines

scientific article

Cystic fibrosis fatty acid imbalance is linked to ceramide deficiency and corrected by fenretinide.

scientific article

Cytotoxic conjugates of betulinic acid and substituted triazoles prepared by Huisgen Cycloaddition from 30-azidoderivatives

scientific article

Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid.

scientific article published on 11 April 2012

Czech and Slovak Diamond-Blackfan Anemia (DBA) Registry update: Clinical data and novel causative genetic lesions

scientific article published on 11 November 2019

Detection of minimal residual disease in lung cancer.

scientific article published on 02 April 2013

Diagnostic and prognostic potential of miR-21, miR-29c, miR-148 and miR-203 in adenocarcinoma and squamous cell carcinoma of esophagus

scientific article published on 28 April 2015

Differences in the importance of microcephaly, dysmorphism, and epilepsy in the detection of pathogenic CNVs in ID and ASD patients

scientific article published on 15 November 2019

Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs

scientific article published on 12 August 2018

Discrimination of circulating tumor cells of breast cancer and colorectal cancer from normal human mononuclear cells using Raman spectroscopy

scientific article published on 01 October 2013

Disulfiram's anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase

scientific article published on 07 August 2019

Dumbbell-shaped peripheral primitive neuroectodermal tumor of the spine--case report and review of the literature

scientific article published on 03 December 2008

Dynamic changes in microRNA expression profiles reflect progression of Barrett's esophagus to esophageal adenocarcinoma

scientific article published on 16 March 2015

Early and Non-invasive Diagnosis of Aspergillosis Revealed by Infection Kinetics Monitored in a Rat Model

scientific article published on 08 October 2018

Effects of Ginger Phenylpropanoids and Quercetin on Nrf2-ARE Pathway in Human BJ Fibroblasts and HaCaT Keratinocytes

scientific article published on 28 January 2016

Efficacy and Toxicity of Panitumumab After Progression on Cetuximab and Predictive Value of MiR-31-5p in Metastatic Wild-type KRAS Colorectal Cancer Patients

scientific article published in September 2016

Epidermal growth factor receptor (EGFR) expression and mutations in the EGFR signaling pathway in correlation with anti-EGFR therapy in head and neck squamous cell carcinomas

scientific article published in January 2012

Epidermal growth factor receptor as a predictor of tumor response to preoperative chemoradiation in locally advanced gastric carcinoma.

scientific article published on 19 November 2008

Estradiol dimer inhibits tubulin polymerization and microtubule dynamics

scientific article published on 24 May 2018

European Health Data Space-An Opportunity Now to Grasp the Future of Data-Driven Healthcare

scientific article published on 26 August 2022

Evaluation of HER2 Gene Status in Breast Cancer Samples with Indeterminate Fluorescence in Situ Hybridization by Quantitative Real-Time PCR.

scientific article published on 5 May 2015

Evaluation of laparoscopic resection of colorectal carcinoma from the viewpoint of molecular biology.

scientific article published on 10 November 2011

Evaporation-reducing Culture Condition Increases the Reproducibility of Multicellular Spheroid Formation in Microtiter Plates

scientific article published on 07 March 2017

Expression of Concern for "Identification of Eukaryotic Translation Elongation Factor 1-α 1 Gamendazole-Binding Site for Binding of 3-Hydroxy-4(1H)-quinolinones as Novel Ligands with Anticancer Activity"

scientific article published on 09 September 2019

Fenretinide corrects newly found ceramide deficiency in cystic fibrosis

scientific article (publication date: 2008)

Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme: evidence from bench to bedside.

scientific article

Fenretinide favorably affects mucins (MUC5AC/MUC5B) and fatty acid imbalance in a manner mimicking CFTR-induced correction

scientific article published on 31 October 2019

Fenretinide prevents inflammation and airway hyperresponsiveness in a mouse model of allergic asthma.

scientific article

Fetal colon cell line FHC exhibits tumorigenic phenotype, complex karyotype, and TP53 gene mutation.

scientific article

Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors

scientific article published on 21 February 2020

Fluridil, a rationally designed topical agent for androgenetic alopecia: first clinical experience

scientific article

Frequency of 657del(5) mutation of the NBS1 gene in the Czech population by polymerase chain reaction with sequence specific primers

scientific article published on October 2002

Frequency of chromosome 17 polysomy in relation to CEP17 copy number in a large breast cancer cohort

scientific article published on 05 February 2016

Functional p53 in cells contributes to the anticancer effect of the cyclin-dependent kinase inhibitor roscovitine

scientific article published on June 2009

Generalization of DNA microarray dispersion properties: microarray equivalent of t-distribution

scientific article

Genetic Markers in Triple-Negative Breast Cancer

scientific article published on 04 August 2018

Glioblastoma multiforme with an abscess: case report and literature review

scientific article

Head-To-Head Comparison of Biological Behavior of Biocompatible Polymers Poly(Ethylene Oxide), Poly(2-Ethyl-2-Oxazoline) and Poly[N-(2-Hydroxypropyl)Methacrylamide] as Coating Materials for Hydroxyapatite Nanoparticles in Animal Solid Tumor Model

scientific article published on 27 August 2020

Hepatoprotective effect of MMP-19 deficiency in a mouse model of chronic liver fibrosis

scientific article (publication date: 2012)

Hepcidin levels in Diamond-Blackfan anemia reflect erythropoietic activity and transfusion dependency

scientific article

Herbal composition PC-SPES for management of prostate cancer: identification of active principles.

scientific article

Heterogenous mutation spectrum and deregulated cellular pathways in aberrant plasma cells underline molecular pathology of light-chain amyloidosis

scientific article published on 07 May 2020

High lapatinib plasma levels in breast cancer patients: risk or benefit?

scientific article

Human virus detection with graphene-based materials

scientific article published on 22 July 2020

IDH Mutation Analysis in Glioma Patients by CADMA Compared with SNaPshot Assay and two Immunohistochemical Methods.

scientific article

Identification of Eukaryotic Translation Elongation Factor 1-α 1 Gamendazole-Binding Site for Binding of 3-Hydroxy-4(1 H)-quinolinones as Novel Ligands with Anticancer Activity.

scientific article published on 2 March 2018

Identification of Meningioma Patients at High Risk of Tumor Recurrence Using MicroRNA Profiling

scientific article published on 03 March 2020

Imaging of Pseudomonas aeruginosa infection with Ga-68 labelled pyoverdine for positron emission tomography

scientific article published in Scientific Reports

Importance of Hepcidin in the Etiopathogenesis of Anemia in Inflammatory Bowel Disease

scientific article published on 16 October 2020

Importance of miRNA in SARS-CoV2 infection

scientific article published on 5 December 2020

In Search of System-Wide Productivity Gains - The Role of Global Collaborations in Preclinical Translation.

scientific article

Increased lipid peroxidation and abnormal fatty acid profiles in seminal and blood plasma of normozoospermic males from infertile couples.

scientific article published on 25 November 2009

Induction of apoptosis and regression of spontaneous dog melanoma following in vivo application of synthetic cyclin-dependent kinase inhibitor olomoucine

scientific article published on 01 November 1997

Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence

scientific article published in March 2018

Influence of esterification and modification of A-ring in a group of lupane acids on their cytotoxicity

scientific article published on October 2005

Influence of the bcg locus on natural resistance to primary infection with the facultative intracellular bacterium Francisella tularensis in mice

scientific article

Integrated physical map of bread wheat chromosome arm 7DS to facilitate gene cloning and comparative studies

scientific article published in January 2019

Intramedullary spinal cord and cauda equina metastasis of breast carcinoma: case report.

scientific article published in June 2010

Isocitrate Dehydrogenase Mutations are Better Prognostic Marker than O6-methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastomas - a Retrospective, Single-centre Molecular Genetics Study of Gliomas.

scientific article published in January 2017

Isocitrate dehydrogenase 1 and 2 mutations in gliomas.

scientific article

Lapatinib in breast cancer - the predictive significance of HER1 (EGFR), HER2, PTEN and PIK3CA genes and lapatinib plasma level assessment

scientific article published on December 2010

Long term follow-up of neoadjuvant-adjuvant combination treatment of IIIA stage non-small-cell-lung cancer: results of neoadjuvant carboplatin/vinorelbine and carboplatin/paclitaxel regimens combined with selective adjuvant chemotherapy according to

scientific article published in December 2008

Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells.

scientific article published on 17 May 2016

Lycopene improves the distorted ratio between AA/DHA in the seminal plasma of infertile males and increases the likelihood of successful pregnancy

article

MEG3: a novel long noncoding potentially tumour-suppressing RNA in meningiomas

scientific article published on 11 January 2013

MLPA is a practical and complementary alternative to CMA for diagnostic testing in patients with autism spectrum disorders and identifying new candidate CNVs associated with autism

scientific article published on 09 January 2019

MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function.

scientific article published on 11 November 2015

Magnetically assisted surface-enhanced raman scattering selective determination of dopamine in an artificial cerebrospinal fluid and a mouse striatum using Fe(3)O(4)/Ag nanocomposite.

scientific article

Mass Spectrometry Amyloid Typing Is Reproducible across Multiple Organ Sites

scientific article published on 31 January 2019

Merkel Cell Carcinoma of the Gluteal Region with Ipsilateral Metastasis into the Pancreatic Graft of a Patient after Combined Kidney-Pancreas Transplantation ⬇️

scientific article published on September 20, 2010

Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX

scientific article published on 16 October 2019

MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients

scientific article

MiR-205 functions as a tumor suppressor in adenocarcinoma and an oncogene in squamous cell carcinoma of esophagus.

scientific article published on 28 December 2015

MicroRNAs and glioblastoma: roles in core signalling pathways and potential clinical implications

scientific article published on August 2011

Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer's disease

scientific article

Minimal information for Chemosensitivity assays (MICHA): A next-generation pipeline to enable the FAIRification of drug screening experiments ⬇️

scientific article published on 04 December 2020

Montelukast decreases plasma endothelin-1 and serum eosinophil cationic protein levels in paediatric atopic asthma

scientific article published on 01 January 2006

Multicentre validation of a microRNA-based assay for diagnosing indeterminate thyroid nodules utilising fine needle aspirate smears.

scientific article

N-Benzyl Substitution of Polyhydroxypyrrolidines: The Way to Selective Inhibitors of Golgi α-Mannosidase II.

scientific article published on 11 January 2018

N-glycoprotein SRMAtlas: a resource of mass spectrometric assays for N-glycosites enabling consistent and multiplexed protein quantification for clinical applications

scientific article

Natural resistance to infection with intracellular pathogens: Cross‐talk between Nramp1 and Lps genes ⬇️

scientific article published on December 1, 1997

New derivatives of silybin and 2,3-dehydrosilybin and their cytotoxic and P-glycoprotein modulatory activity.

scientific article published on 8 February 2006

New lupane derived compounds with pro-apoptotic activity in cancer cells: synthesis and structure-activity relationships

scientific article published on December 2003

Newly designed 11-gene panel reveals first case of hereditary amyloidosis captured by massive parallel sequencing.

scientific article published on 17 February 2018

Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects

scientific article published on 24 November 2021

Non-invasive prognostic protein biomarker signatures associated with colorectal cancer

scientific article

Non-small cell lung cancer--genetic predictors

scientific article published on 29 May 2013

Nonribosomal cyclic peptides: specific markers of fungal infections

scientific article published on May 2006

Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis.

scientific article

Nucleosidic DNA demethylating epigenetic drugs - A comprehensive review from discovery to clinic.

scientific article published on 15 February 2018

O6. Circulating tumor cells in the peripheral blood predict poor prognosis in surgically treated non-small cell lung cancer patients

scientific article published in October 2014

Occult tumour cells in peritoneal lavage are a negative prognostic factor in pancreatic cancer.

scientific article published on 31 October 2012

Pathophysiologically relevant in vitro tumor models for drug screening

scientific article published on 20 April 2015

Peloruside A-Induced Cell Death in Hypoxia Is p53 Dependent in HCT116 Colorectal Cancer Cells

scientific article

Pentamethinium salts as ligands for cancer: Sulfated polysaccharide co-receptors as possible therapeutic target

scientific article published on 16 February 2018

Pharmacological activities of natural triterpenoids and their therapeutic implications.

scientific article published on 3 May 2006

Pitfalls of commercially available HPV tests in HPV68a detection

scientific article published on 05 August 2019

Prediction of colorectal cancer diagnosis based on circulating plasma proteins

scientific article

Preparation of Conjugates of Cytotoxic Lupane Triterpenes with Biotin.

scientific article published on 5 November 2015

Preparation, preliminary screening of new types of steroid conjugates and their activities on steroid receptors

scientific article

Prevalence of human papillomavirus infection in oocyte donors and women treated for infertility: An observational laboratory-based study

scientific article published on 04 July 2019

Prognostic value of Bmi-1 oncoprotein expression in NSCLC patients: a tissue microarray study

scientific article published on 09 February 2008

Prognostic value of hMLH1 and hMSH2 immunohistochemical expression in non-small cell lung cancer. A tissue microarray study

scientific article published on 01 November 2006

Prognostic value of tumor-infiltrating lymphocytes (TILs) and their association with PD-L1 expression and DNA repair protein RAD51 in patients with resected non-small cell lung carcinoma

scientific article published on 23 June 2020

Protein fingerprints of anti-cancer effects of cyclin-dependent kinase inhibition: identification of candidate biomarkers using 2-D liquid phase separation coupled to mass spectrometry.

scientific article published in August 2005

Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells.

scientific article published on 3 May 2017

Proteomics study of silver nanoparticles on Caco-2 cells

scientific article published on 4 April 2018

Putting translational science on to a global stage

scientific article published on April 2016

Pyrido-Fused Deazapurine Bases: Synthesis and Glycosylation of 4-Substituted 9H-Pyrido[2',3':4,5]- and Pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidines

scientific article published on 02 October 2020

Recurrence of surgically treated parasagittal meningiomas: a meta-analysis of risk factors

scientific article published on 24 April 2020

Reproducibility of Uniform Spheroid Formation in 384-Well Plates: The Effect of Medium Evaporation

scientific article published on 25 May 2016

Risk Score based on microRNA expression signature is independent prognostic classifier of glioblastoma patients.

scientific article published on 16 October 2014

Role of CCND1 and C-MYC oncogenes in metastatic breast cancer patients treated by herceptin.

scientific article published on 16 November 2011

Role of Salmonella Typhi Vi Antigen and Secretory Systems on Immune Response

scientific article published on 29 August 2016

Role of tumor hypoxia in acquisition of resistance to microtubule-stabilizing drugs.

scientific article published on 07 February 2015

Striking antitumor activity of a methinium system with incorporated quinoxaline unit obtained by spontaneous cyclization

scientific article

Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides

scientific article

Sugar modified pyrimido[4,5-]indole nucleosides: synthesis and antiviral activity

scientific article published on 25 August 2017

Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX

scientific article published on 18 May 2020

Synthesis and Biological Profiling of Pyrazolo-fused 7-Deazapurine Nucleosides

scientific article published on 21 July 2020

Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.

scientific article published on 21 February 2017

Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid

scientific article published on 13 January 2017

Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides

scientific article published on 10 April 2020

Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-fused 7-Deazapurine Ribonucleosides

scientific article published on 3 October 2018

Synthesis and antiproliferative properties of new hydrophilic esters of triterpenic acids

scientific article

Synthesis and biological activity evaluation of hydrazone derivatives based on a Tröger’s base skeleton

scientific article published on 23 January 2015

Synthesis and biological evaluation of cis-restrained carbocyclic combretastatin A-4 analogs: Influence of the ring size and saturation on cytotoxic properties

scientific article published on 29 July 2019

Synthesis and biological evaluation of triterpenoid thiazoles derived from betulonic acid, dihydrobetulonic acid, and ursonic acid

scientific article published on 24 October 2019

Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4'-C-methylribonucleosides.

scientific article published on 31 October 2015

Synthesis and cytotoxic activity of substituted 2-phenyl-3-hydroxy-4(1H)-quinolinones-7-carboxylic acids and their phenacyl esters.

scientific article published on 15 March 2006

Synthesis and cytotoxic activity of various 5-[alkoxy-(4-nitro-phenyl)-methyl]-uracils in their racemic form.

scientific article

Synthesis and cytotoxicity of some D-mannose click conjugates with aminobenzoic acid derivatives.

scientific article published on 10 August 2012

Synthesis and significant cytostatic activity of 7-hetaryl-7-deazaadenosines

scientific article published on 11 July 2011

Synthesis of 2-aryl-4-(benzimidazol-2-yl)-1,2-dihydro[1,2,4]triazino-[4,5-a]benzimidazol-1-one derivatives with preferential cytotoxicity against carcinoma cell lines.

scientific article published on 25 January 2007

Synthesis of 5-[alkoxy-(4-nitro-phenyl)-methyl]-uridines and study of their cytotoxic activity.

scientific article published on 12 May 2010

Synthesis of A-seco derivatives of betulinic acid with cytotoxic activity

scientific article published on July 2004

Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells.

scientific article published on April 2015

Synthesis of phthalates of betulinic acid and betulin with cytotoxic activity

scientific article published in May 2005

Synthesis of various 5-alkoxymethyluracil analogues and structure-cytotoxic activity relationship study

scientific article

Synthesis, Photophysical Properties and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides

scientific article published on 20 May 2020

Synthesis, cytostatic, antimicrobial, and anti-HCV activity of 6-substituted 7-(het)aryl-7-deazapurine ribonucleosides

scientific article published on 16 January 2014

Synthetic approach for rapid preparation of BODIPY conjugates and their use in imaging of cellular drug uptake and distribution.

scientific article published on 7 February 2018

Synthetic inhibitors of CDKs induce different responses in androgen sensitive and androgen insensitive prostatic cancer cell lines.

scientific article published on August 2002

TLR 7/8 Ligand, S28463, Suppresses Ascaris Suum Induced Allergic Asthma in Nonhuman Primates

scientific article published on 29 August 2017

The Fundamental Characteristics of a Translational Scientist

scientific article published on 02 May 2019

The absence of high-risk human papillomavirus in Czech non-small cell lung cancer cases

scientific article published on 10 January 2019

The analysis of correlations between drug resistance and clinical/laboratory measures found in a group of children with all treated by ALL-BFM 90 protocol.

scientific article published in April 2004

The anti-inflammatory effects of inhaled corticosteroids versus anti-leukotrienes on the lymphocyte P-glycoprotein (PGP) expression in asthmatic children.

scientific article published in May 2009

The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain.

scientific article

The natural cytokinin 2OH3MeOBAR induces cell death by a mechanism that is different from that of the "classical" cytokinin ribosides

scientific article

The radiosensitising effect of olomoucine derived synthetic cyclin-dependent kinase inhibitors.

scientific article

The status and role of ErbB receptors in human cancer.

scientific article published on 05 January 2008

Treatment and prognosis of childhood acute lymphoblastic leukemia on protocols ALL-BFM 90, 95 and ALL IC-BFM 2002: a retrospective single-center study from Olomouc, Czech Republic

scientific article published in March 2016

Treatment of allergic asthma with Fenretinide formulation (LAU-7b) downregulates Ormdl3 expression and normalizes ceramides imbalance

scientific article published on 09 April 2020

Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity.

scientific article published on 17 August 2016

Triple negative breast cancer--current status and prospective targeted treatment based on HER1 (EGFR), TOP2A and C-MYC gene assessment.

scientific article published on March 2009

Triterpenic azines, a new class of compounds with selective cytotoxicity to leukemia cells CCRF-CEM.

scientific article published on 9 February 2018

Triterpenoid pyrazines and benzopyrazines with cytotoxic activity

scientific article published on 20 March 2007

Utilization of high-accuracy FTICR-MS data in protein quantitation experiments

scientific article published in November 2009

Whole Exome Sequencing of Aberrant Plasma Cells in a Patient with Multiple Myeloma Minimal Residual Disease.

scientific article published in January 2017

Whole genome amplification induced bias in the detection of KRAS-mutated cell populations during colorectal carcinoma tissue testing

scientific article published on 19 February 2015

YAP regulates cell mechanics by controlling focal adhesion assembly

scientific article

[KRAS mutation testing in therapeutic algorithm for treatment of metastatic colorectal carcinoma]

scientific article published on 01 January 2011

[Possibility of using the determination of minimal residual disease in pancreatic adenocarcinoma using real-time RT-PCR--a pilot study].

scientific article

p53--prognostic factor of malignant transformation of Barrett's esophagus

scientific article published on 01 June 2005

Prediktivní a prognostická onkologie

book edition published in 2016

Paulina is supported by:

About Paulina

Help