List of works - Naoki Nishizawa

A PEGylated analog of short-length Neuromedin U with potent anorectic and anti-obesity effects

scientific article published on 21 February 2017

A Short-Length Peptide YY Analogue with Anorectic Effect in Mice.

scientific article published on 18 May 2017

A potent and selective natriuretic peptide receptor-3 blocker 11-mer peptide created by hybridization of musclin and atrial natriuretic peptide.

scientific article published on 20 May 2017

A potent neuromedin U receptor 2-selective alkylated peptide.

scientific article

Antiobesity Effect of a Short-Length Peptide YY Analogue after Continuous Administration in Mice.

scientific article published in May 2017

Antiobesity and emetic effects of a short-length peptide YY analog and its PEGylated and alkylated derivatives

scientific article published on 8 December 2017

Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum

scientific article

Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.

scientific article

Chronic Administration of the Metastin/Kisspeptin Analog KISS1-305 or the Investigational Agent TAK-448 Suppresses Hypothalamic Pituitary Gonadal Function and Depletes Plasma Testosterone in Adult Male Rats ⬇️

scientific article published on October 1, 2012

Design and Synthesis of an Investigational Nonapeptide KISS1 Receptor (KISS1R) Agonist, Ac-d-Tyr-Hydroxyproline (Hyp)-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2 (TAK-448), with Highly Potent Testosterone-Suppressive Activity and Excellent Water Solubili

scientific article published on 2 September 2016

Design, synthesis, and biological evaluation of novel investigational nonapeptide KISS1R agonists with testosterone-suppressive activity

scientific article published on 17 October 2013

Development and validation of sensitive sandwich ELISAs for two investigational nonapeptide metastin receptor agonists, TAK-448 and TAK-683

scientific article published on 01 June 2012

Differential effects of selective agonists of neuromedin U1 and U2 receptors in obese and diabetic mice.

scientific article

Effects of peripheral administration of a Neuromedin U receptor 2-selective agonist on food intake and body weight in obese mice.

scientific article published on 31 July 2017

Highly potent antiobesity effect of a short-length peptide YY analog in mice

scientific article published in September 2017

Isostearyl Mixed Anhydrides for the Preparation of N-Methylated Peptides Using C-Terminally Unprotected N-Methylamino Acids

scientific article published on 02 October 2020

Molecular properties of apelin: tissue distribution and receptor binding

scientific journal article

Physicochemically and pharmacokinetically stable nonapeptide KISS1 receptor agonists with highly potent testosterone-suppressive activity.

scientific article published on 7 July 2014

Potent Body Weight-Lowering Effect of a Neuromedin U Receptor 2-selective PEGylated Peptide.

scientific article published on 28 June 2017

Potent antiobesity effect of a short-length peptide YY-analogue continuously administered in mice

scientific article

Serum stability of selected decapeptide agonists of KISS1R using pseudopeptides

scientific article published on 23 August 2012

Trypsin resistance of a decapeptide KISS1R agonist containing an Nω-methylarginine substitution.

scientific article published on 30 August 2012

List of works by Naoki Nishizawa

A PEGylated analog of short-length Neuromedin U with potent anorectic and anti-obesity effects

A Short-Length Peptide YY Analogue with Anorectic Effect in Mice.

A potent and selective natriuretic peptide receptor-3 blocker 11-mer peptide created by hybridization of musclin and atrial natriuretic peptide.

A potent neuromedin U receptor 2-selective alkylated peptide.

Antiobesity Effect of a Short-Length Peptide YY Analogue after Continuous Administration in Mice.

Antiobesity and emetic effects of a short-length peptide YY analog and its PEGylated and alkylated derivatives

Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum

Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.

Chronic Administration of the Metastin/Kisspeptin Analog KISS1-305 or the Investigational Agent TAK-448 Suppresses Hypothalamic Pituitary Gonadal Function and Depletes Plasma Testosterone in Adult Male Rats ⬇️

Design and Synthesis of an Investigational Nonapeptide KISS1 Receptor (KISS1R) Agonist, Ac-d-Tyr-Hydroxyproline (Hyp)-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2 (TAK-448), with Highly Potent Testosterone-Suppressive Activity and Excellent Water Solubili

Design, synthesis, and biological evaluation of novel investigational nonapeptide KISS1R agonists with testosterone-suppressive activity

Development and validation of sensitive sandwich ELISAs for two investigational nonapeptide metastin receptor agonists, TAK-448 and TAK-683

Differential effects of selective agonists of neuromedin U1 and U2 receptors in obese and diabetic mice.

Effects of peripheral administration of a Neuromedin U receptor 2-selective agonist on food intake and body weight in obese mice.

Highly potent antiobesity effect of a short-length peptide YY analog in mice

Isostearyl Mixed Anhydrides for the Preparation of N-Methylated Peptides Using C-Terminally Unprotected N-Methylamino Acids

Molecular properties of apelin: tissue distribution and receptor binding

Physicochemically and pharmacokinetically stable nonapeptide KISS1 receptor agonists with highly potent testosterone-suppressive activity.

Potent Body Weight-Lowering Effect of a Neuromedin U Receptor 2-selective PEGylated Peptide.

Potent antiobesity effect of a short-length peptide YY-analogue continuously administered in mice

Serum stability of selected decapeptide agonists of KISS1R using pseudopeptides

Trypsin resistance of a decapeptide KISS1R agonist containing an Nω-methylarginine substitution.