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List of works by Matias Avila

5'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes.

scientific article published on April 2004

A GAPDH-mediated trans-nitrosylation pathway is required for feedback inhibition of bile salt synthesis in rat liver

scientific article published on 25 July 2014

A Novel Serum Metabolomic Profile for the Differential Diagnosis of Distal Cholangiocarcinoma and Pancreatic Ductal Adenocarcinoma

scientific article published on 31 May 2020

A phosphatidylinositol-linkage-deficient T-cell mutant contains insulin-sensitive glycosyl-phosphatidylinositol

scientific article published on March 15, 1992

Altered processing of precursor transcripts and increased levels of the subunit I of mitochondrial cytochrome c oxidase in Syrian hamster fetal cells initiated with ionizing radiation

scientific article published on August 1, 1997

Amphiregulin

scientific article published on 23 January 2014

Amphiregulin Aggravates Glomerulonephritis via Recruitment and Activation of Myeloid Cells

scientific article published on 02 July 2020

Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells.

scientific article published on June 2006

Amphiregulin: a new growth factor in hepatocarcinogenesis.

scientific article published on 26 February 2007

Amphiregulin: an early trigger of liver regeneration in mice.

scientific article

Authors' response: observations suggesting bioactive Fgf15 is not present in mouse blood.

scientific article published on 13 June 2013

Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications.

scientific article

Chromatin dynamics during liver regeneration

scientific article published on 09 April 2019

Current and innovative emerging therapies for porphyrias with hepatic involvement

scientific article published on 16 May 2019

DNA Methylation Regulates a Set of Long Non-Coding RNAs Compromising Hepatic Identity during Hepatocarcinogenesis

scientific article published on 19 April 2022

DNA methylation and histone acetylation of rat methionine adenosyltransferase 1A and 2A genes is tissue-specific

scientific article published on 01 April 2000

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

scientific article published on 16 July 2019

Differential regulation of the JNK/AP-1 pathway by S-adenosylmethionine and methylthioadenosine in primary rat hepatocytes versus HuH7 hepatoma cells.

scientific article published on 9 February 2006

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

scientific article

Dual Pharmacological Targeting of HDACs and PDE5 Inhibits Liver Disease Progression in a Mouse Model of Biliary Inflammation and Fibrosis

scientific article published on 13 December 2020

Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma

scientific article published on 04 January 2019

Emerging therapies for acute intermittent porphyria.

scientific article published on 2 November 2016

Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice

scientific article published on 5 October 2017

Enoxaparin reduces hepatic vascular resistance and portal pressure in cirrhotic rats

scientific article

Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer.

scientific article published on 18 May 2011

Epidermal growth factor receptor signaling in hepatocellular carcinoma: inflammatory activation and a new intracellular regulatory mechanism.

scientific article

Epigenetic Mechanisms in Gastric Cancer: Potential New Therapeutic Opportunities

scientific article published on 31 July 2020

Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib

scientific article published on 11 February 2019

Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis

scientific article published on 23 April 2020

Epigenetics in Liver Fibrosis: Could HDACs be a Therapeutic Target?

scientific article published on 19 October 2020

FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted

scientific article published in August 2021

Fibroblast Growth Factor 15/19 in Hepatocarcinogenesis.

scientific article published on March 2017

Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration

scientific article published on 24 January 2017

Fibroblast growth factors 19 and 21 in acute liver damage.

scientific article published in June 2018

Further evidence on the janus-faced nature of the epidermal growth factor receptor: From liver regeneration to hepatocarcinogenesis.

scientific article published on 9 December 2015

GARBAN: genomic analysis and rapid biological annotation of cDNA microarray and proteomic data.

scientific article published in November 2003

Glycosyl-phosphatidylinositol/inositol phosphoglycan: a signaling system for the low-affinity nerve growth factor receptor

scientific article published on September 15, 1991

Gut roundtable meeting paper: selected recent advances in hepatocellular carcinoma.

scientific article published on 17 November 2017

Hepatitis B virus x protein and pin1 in liver cancer: "les liaisons dangereuses".

scientific article published in March 2007

Hepatocellular Carcinoma: Updates in Pathogenesis, Detection and Treatment

scientific article published on 23 September 2020

Hepatocyte growth factor induces MAT2A expression and histone acetylation in rat hepatocytes: role in liver regeneration

scientific article published on 01 May 2001

Identification of argininosuccinate lyase as a hypoxia-responsive gene in rat hepatocytes

scientific journal article

Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development

scientific article

Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A.

scientific article published on 19 March 2004

Impairment of pre-mRNA splicing in liver disease: mechanisms and consequences.

scientific article published on July 2010

Induction of TIMP-1 expression in rat hepatic stellate cells and hepatocytes: a new role for homocysteine in liver fibrosis

scientific article published on 01 September 1999

Influence of impaired liver methionine metabolism on the development of vascular disease and inflammation.

scientific article

Inhibiting Cytokinesis in the Liver: A New Way to Reduce Tumor Development.

scientific article published on 3 March 2018

Inhibition of liver methionine adenosyltransferase gene expression by 3-methylcolanthrene: protective effect of S-adenosylmethionine.

scientific article published in May 2001

Insulin-Like Effects of Inositol Phosphate-Glycan on Messenger RNA Expression in Rat Hepatocytes

scientific article published on 01 August 1991

Interaction of glucocorticoids with FXR/FGF19/FGF21-mediated ileum-liver crosstalk

scientific article published on 06 June 2018

Isolation and characterization of SpTRK, a gene from schizosaccharomyces pombe predicted to encode a K+ transporter protein

scientific article published on August 8, 1995

L-Arginine decreases fluid-percussion injury-induced neuronal nitrotyrosine immunoreactivity in rats.

scientific article published on 9 July 2008

LKB1: Controlling Quiescence and Genomic Integrity at Home.

scientific article published on 5 April 2018

Lack of Abcc3 expression impairs bile-acid induced liver growth and delays hepatic regeneration after partial hepatectomy in mice.

scientific article published on 12 July 2011

Liver-specific methionine adenosyltransferase MAT1A gene expression is associated with a specific pattern of promoter methylation and histone acetylation: implications for MAT1A silencing during transformation.

scientific article

Long distance calling for liver regeneration: Identification of neuroendocrine signalling pathways activated after partial hepatectomy

scientific article published on September 19, 2010

Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma

scientific article published on 16 April 2020

MEF2D Transduces Microenvironment Stimuli to ZEB1 to Promote Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer

scientific article published on 30 June 2016

Making sorafenib irresistible: In vivo screening for mechanisms of therapy resistance in hepatocellular carcinoma hits on Mapk14.

scientific article published on 20 March 2015

Matrix metalloproteinase 10 contributes to hepatocarcinogenesis in a novel crosstalk with the stromal derived factor 1/C-X-C chemokine receptor 4 axis

scientific article

Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair

scientific article published on 16 October 2013

Messenger RNA therapy for rare genetic metabolic diseases

scientific article published on 22 February 2019

Methylthioadenosine phosphorylase gene expression is impaired in human liver cirrhosis and hepatocarcinoma

scientific article

Methylthioadenosine.

scientific article published in November 2004

MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

scientific article published on 20 September 2018

Multi-Omics Integration Highlights the Role of Ubiquitination in CCl<sub>4</sub>-Induced Liver Fibrosis

scientific article published on 27 November 2020

New mechanisms involving the EGFR and FGF15/19 systems in liver regeneration and carcinogenesis.

scientific article

New molecular interactions of c-Myc in cholangiocarcinoma may open new therapeutic opportunities.

scientific article published on 21 April 2016

New therapies for hepatocellular carcinoma.

scientific article published on June 2006

Novel pharmacologic strategies to protect the liver from ischemia-reperfusion injury

scientific article published on 01 January 2008

Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice

scientific article

Overexpression of the transcription factor MEF2D in hepatocellular carcinoma sustains malignant character by suppressing G2-M transition genes.

scientific article published on 3 January 2014

Oxidation of specific methionine and tryptophan residues of apolipoprotein A-I in hepatocarcinogenesis.

scientific article

Physiological and enzymatic alterations in sesame seeds submitted to different osmotic potentials.

scientific article published on 17 August 2017

Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach

scientific article published on 21 June 2020

Platelet-derived growth factor D: a new player in the complex cross-talk between cholangiocarcinoma cells and cancer-associated fibroblasts.

scientific article published on 22 July 2013

Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease.

scientific article published on 23 June 2016

Prioritizing Popular Proteins in Liver Cancer: Remodelling One-Carbon Metabolism.

scientific article

Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF

scientific journal article

Radioembolization of hepatocellular carcinoma activates liver regeneration, induces inflammation and endothelial stress and activates coagulation

scientific article published on 03 June 2014

Recent advances in alcohol-related liver disease (ALD): summary of a Gut round table meeting

scientific article published on 26 December 2019

Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma

scientific article published on 01 December 2000

Regulation by hypoxia of methionine adenosyltransferase activity and gene expression in rat hepatocytes

scientific article published on 01 February 1998

Regulation of hepatocyte identity and quiescence.

scientific article published on 19 June 2015

S-Adenosylmethionine modulates inducible nitric oxide synthase gene expression in rat liver and isolated hepatocytes

scientific article published on 01 December 2001

S-Adenosylmethionine: a control switch that regulates liver function.

scientific article

S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells.

scientific article published in February 2002

S-adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S-adenosylmethionine in the maintenance of the differentiated status of the liver

scientific journal article

SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer

scientific article published on 26 December 2018

Secretion of neu differentiation factor-like polypeptides by cph-transformed fibroblasts: cloning and characterization of Syrian hamster neuregulin cDNAs.

scientific article

Serum metabolites as diagnostic biomarkers for cholangiocarcinoma, hepatocellular carcinoma and primary sclerosing cholangitis

scientific article published on 14 February 2019

Specific interaction of methionine adenosyltransferase with free radicals.

scientific article published in January 1998

Splicing alterations contributing to cancer hallmarks in the liver: central role of dedifferentiation and genome instability

scientific article published on 31 October 2018

Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins

scientific article published on 01 April 2019

Splicing regulator SLU7 is essential for maintaining liver homeostasis

scientific article published on 27 May 2014

Splicing regulator SLU7 preserves survival of hepatocellular carcinoma cells and other solid tumors via oncogenic miR-17-92 cluster expression

scientific article published on 25 January 2016

Systemic messenger RNA as an etiological treatment for acute intermittent porphyria

article

Targeting CCL2/CCR2 in Tumor-Infiltrating Macrophages: A Tool Emerging Out of the Box Against Hepatocellular Carcinoma

scientific article published on 04 December 2018

The EGFR signalling system in the liver: from hepatoprotection to hepatocarcinogenesis

scientific article published on 10 December 2013

The FXR-FGF19 Gut-Liver Axis as a Novel "Hepatostat".

scientific article published on 27 July 2015

The anticoagulant rivaroxaban lowers portal hypertension in cirrhotic rats mainly by deactivating hepatic stellate cells.

scientific article

The epidermal growth factor receptor ligand amphiregulin is a negative regulator of hepatic acute-phase gene expression.

scientific article published on 12 September 2009

The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis.

scientific article

The epidermal growth factor receptor: a link between inflammation and liver cancer.

scientific article published on 08 May 2009

The response of the hepatocyte to ischemia.

scientific article published on February 2007

The search for novel diagnostic and prognostic biomarkers in cholangiocarcinoma

scientific article

Toll-like receptor-4 expression by hepatic progenitor cells and biliary epithelial cells in HCV-related chronic liver disease.

scientific article published on 16 December 2011

Transformed but not normal hepatocytes express UCP2

scientific article published on 01 November 1998

Up-regulation of the anti-inflammatory adipokine adiponectin in acute liver failure in mice.

scientific article

Wilms' tumor 1 gene expression in hepatocellular carcinoma promotes cell dedifferentiation and resistance to chemotherapy.

scientific article

delta-9-Tetrahydrocannabinol increases prodynorphin and proenkephalin gene expression in the spinal cord of the rat.

scientific article published on January 1997