List of works - Atsushi Enomoto

A Case of Sialolithiasis in a Minor Salivary Gland of the Buccal Mucosa

scientific article published on November 2016

A novel Drosophila Girdin-like protein is involved in Akt pathway control of cell size.

scientific article published on 26 June 2009

A rare pseudo tumour in the extraembryonic coelom in first trimester of pregnancy: ultrasound and pathology

scientific article published on 08 November 2018

ASC amino acid transporter 2, defined by enzyme-mediated activation of radical sources, enhances malignancy of GD2-positive small-cell lung cancer.

scientific article published on 19 November 2017

Aberrant Active cis-Regulatory Elements Associated with Downregulation of RET Finger Protein Overcome Chemoresistance in Glioblastoma

scientific article published on 01 February 2019

Accumulation of indoxyl sulfate in OAT1/3-positive tubular cells in kidneys of patients with chronic renal failure

scientific article published on 01 July 2006

Activation of c-Jun amino-terminal kinase by GDNF induces G2/M cell cycle delay linked with actin reorganization.

scientific article published on July 2005

Adiponectin promotes migration activities of endothelial progenitor cells via Cdc42/Rac1

scientific article

Akt-Girdin as oncotarget.

scientific article published on 2 September 2015

Akt-Girdin signaling in cancer-associated fibroblasts contributes to tumor progression.

scientific article published in March 2015

Akt-dependent Girdin phosphorylation regulates repair processes after acute myocardial infarction

scientific article

Akt/PKB regulates actin organization and cell motility via Girdin/APE

scientific article

An inhibitor of advanced glycation end product formation reduces N epsilon-(carboxymethyl)lysine accumulation in glomeruli of diabetic rats.

scientific article

Analysis of glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 expression in human diseased kidney.

scientific article published on 2 February 2011

Autoantibodies to transient receptor potential cation channel, subfamily M, member 1 in a Japanese patient with melanoma-associated retinopathy

scientific article published on 29 January 2014

Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse.

scientific article published on 8 September 2011

CD109 deficiency induces osteopenia with an osteoporosis-like phenotype in vivo

scientific article published on 16 May 2018

CD109 regulates in vivo tumor invasion in lung adenocarcinoma through TGF-β signaling

scientific article published on 02 October 2020

CD109: a multifunctional GPI-anchored protein with key roles in tumor progression and physiological homeostasis

scientific article published on 01 May 2019

Cancer-associated fibroblasts in gastrointestinal cancer

scientific article published on 01 May 2019

Cancer-associated fibroblasts that restrain cancer progression: Hypotheses and perspectives

scientific article published on 14 February 2020

Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress.

scientific article published on 7 April 2009

Chemerin promotes angiogenesis in vivo

scientific article published on 01 December 2018

Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion

scientific article

Clinicopathological and Immunohistochemical Characteristics of Verruciform Xanthoma of the Lower Gingiva: A Case Report

scientific article published on June 2016

Collective invasion of cancer: Perspectives from pathology and development

scientific article published on 21 February 2016

Complex roles of the actin-binding protein Girdin/GIV in DNA damage-induced apoptosis of cancer cells

scientific article published on 02 September 2020

Critical role of rabphilin-3A in the pathophysiology of experimental lymphocytic neurohypophysitis.

scientific article

Cullin-associated NEDD8-dissociated protein 1, a novel interactor of rabphilin-3A, deubiquitylates rabphilin-3A and regulates arginine vasopressin secretion in PC12 cells

scientific article published on 23 January 2018

Cytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice

scientific article published on 6 April 2015

Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus.

scientific article

Degeneration of retinal on bipolar cells induced by serum including autoantibody against TRPM1 in mouse model of paraneoplastic retinopathy

scientific article

Dephosphorylation of Girdin by PP2A inhibits breast cancer metastasis

scientific article published on 29 March 2019

Desmin phosphorylation by Cdk1 is required for efficient separation of desmin intermediate filaments in mitosis and detected in murine embryonic/newborn muscle and human rhabdomyosarcoma tissues

scientific article published on 23 August 2016

Development of a method to preliminarily embed tissue samples using low melting temperature fish gelatin before sectioning: A technical note

scientific article published on 21 February 2018

Epidermal hyperplasia and appendage abnormalities in mice lacking CD109

scientific journal article

Essential Role of Linx/Islr2 in the Development of the Forebrain Anterior Commissure.

scientific article

Evaluation of osteopontin as a potential biomarker for central nervous system embryonal tumors.

scientific article published on 31 May 2014

Expression of Ret finger protein correlates with outcomes in endometrial cancer

scientific article published on 10 July 2009

Function and localization of urate transporter 1 in mouse kidney

scientific journal article

Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules

scientific journal article

GDNF-mediated signaling via RET tyrosine 1062 is essential for maintenance of spermatogonial stem cells.

scientific article published in April 2008

Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain.

scientific article

Girdin is phosphorylated on tyrosine 1798 when associated with structures required for migration

scientific article published on 20 February 2015

Girdin locates in centrosome and midbody and plays an important role in cell division ⬇️

scientific article published on August 1, 2012

Girdin maintains the stemness of glioblastoma stem cells.

scientific article published on 24 October 2011

Girdin phosphorylation is crucial for synaptic plasticity and memory: a potential role in the interaction of BDNF/TrkB/Akt signaling with NMDA receptor.

scientific article published in November 2014

Girdin/GIV regulates collective cancer cell migration by controlling cell adhesion and cytoskeletal organization

scientific article published on 05 October 2018

Girdin/GIV regulates transendothelial permeability by controlling VE-cadherin trafficking through the small GTPase, R-Ras

scientific article published on 11 April 2015

High glucose impairs the proliferation and increases the apoptosis of endothelial progenitor cells by suppression of Akt.

scientific article

High-fat diet feeding promotes stemness and precancerous changes in murine gastric mucosa mediated by leptin receptor signaling pathway.

scientific article

Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins.

scientific article

Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs.

scientific article published on September 2004

IL-15 is elevated in the patients of postoperative enterocolitis

scientific article published on 01 November 1999

Identification of Meflin as a Potential Marker for Mesenchymal Stromal Cells

scientific article published on 29 February 2016

Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency.

scientific article published on 26 October 2014

Indoxyl Sulfate Downregulates Renal Expression of Klotho through Production of ROS and Activation of Nuclear Factor-ĸB ⬇️

scientific article published on March 9, 2011

Indoxyl sulfate promotes cardiac fibrosis with enhanced oxidative stress in hypertensive rats

scientific article published on 21 May 2013

Indoxyl sulfate promotes proliferation of human aortic smooth muscle cells by inducing oxidative stress.

scientific article published in January 2009

Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress

scientific article published on May 2, 2012

Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NF-kappaB activation.

scientific article published on 14 April 2010

Indoxyl sulfate-induced activation of (pro)renin receptor is involved in expression of TGF-β1 and α-smooth muscle actin in proximal tubular cells.

scientific article published on 6 March 2014

Indoxyl sulphate induces oxidative stress and the expression of osteoblast-specific proteins in vascular smooth muscle cells.

scientific article published on 22 January 2009

Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.

scientific article published on March 2003

Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors.

scientific article

Interactions of human organic anion as well as cation transporters with indoxyl sulfate

scientific article published on 01 April 2003

Interactions of human organic anion transporters with diuretics.

scientific article published on 10 November 2003

Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine.

scientific article published in February 2004

Interactions of urate transporter URAT1 in human kidney with uricosuric drugs ⬇️

scientific article published on February 1, 2011

Interleukin 15 activity in the rectal mucosa of inflammatory bowel disease.

scientific article published in June 1998

Involvement of Girdin in the determination of cell polarity during cell migration

scientific article

Metamorphosis of mesothelial cells with active horizontal motility in tissue culture

scientific article

Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition

scientific article

Molecular identification of a renal urate anion exchanger that regulates blood urate levels

scientific article

Molecular mechanism linking BDNF/TrkB signaling with the NMDA receptor in memory: the role of Girdin in the CNS.

scientific article published on March 2016

NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells ⬇️

scientific article published on August 10, 2011

Negative regulation of amino acid signaling by MAPK-regulated 4F2hc/Girdin complex.

scientific article published on 14 March 2018

New endoplasmic reticulum stress regulator, Gipie, regulates the survival of vascular smooth muscle cells and the neointima formation after vascular injury.

scientific article

Nucleolin modulates the subcellular localization of GDNF-inducible zinc finger protein 1 and its roles in transcription and cell proliferation.

scientific article published on 14 July 2007

Potential involvement of kinesin-1 in the regulation of subcellular localization of Girdin.

scientific article published on 10 June 2015

Protective role of Gipie, a Girdin family protein, in endoplasmic reticulum stress responses in endothelial cells ⬇️

scientific article published on February 2, 2011

Proteomic analysis of Girdin-interacting proteins in migrating new neurons in the postnatal mouse brain

scientific journal article

RET receptor signaling: dysfunction in thyroid cancer and Hirschsprung's disease.

scientific article

Rabphilin-3A as a Targeted Autoantigen in Lymphocytic Infundibulo-neurohypophysitis.

scientific article

Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin.

scientific article

Regulation of cargo-selective endocytosis by dynamin 2 GTPase-activating protein girdin

scientific article

Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase.

scientific article published on 5 March 2018

Role for Daple in non-canonical Wnt signaling during gastric cancer invasion and metastasis.

scientific article published on 17 November 2015

Role of Girdin in intimal hyperplasia in vein grafts and efficacy of atelocollagen-mediated application of small interfering RNA for vein graft failure.

scientific article published on 12 August 2013

Role of human organic anion transporter 4 in the transport of ochratoxin A.

scientific article

Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.

scientific article published in September 2009

Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate.

scientific article published on 18 August 2010

Serum levels of IL-10, IL-15 and soluble tumour necrosis factor-alpha (TNF-alpha) receptors in type C chronic liver disease

scientific article

Significance of cancer-associated fibroblasts in the regulation of gene expression in the leading cells of invasive lung cancer.

scientific article published on 30 October 2012

Significance of low mTORC1 activity in defining the characteristics of brain tumor stem cells

scientific article

Significance of perivascular tumour cells defined by CD109 expression in progression of glioma.

scientific article published on 9 September 2017

Similar phenotypes of Girdin germ-line and conditional knockout mice indicate a crucial role for Girdin in the nestin lineage.

scientific article

Speed control for neuronal migration in the postnatal brain by Gmip-mediated local inactivation of RhoA.

scientific article published on 30 July 2014

Suppression of REV7 enhances cisplatin sensitivity in ovarian clear cell carcinoma cells

scientific article

Suppression of skin tumorigenesis in CD109-deficient mice

scientific article published on 14 October 2016

TRIM27/MRTF-B-dependent integrin β1 expression defines leading cells in cancer cell collectives.

scientific article published on May 2014

Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells.

scientific article published on 18 October 2006

The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility.

scientific article published on 29 May 2012

The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse.

scientific article published on 5 March 2013

The actin-binding protein Girdin and its Akt-mediated phosphorylation regulate neointima formation after vascular injury.

scientific article published on 17 March 2011

The intercellular expression of type-XVII collagen, laminin-332, and integrin-β1 promote contact following during the collective invasion of a cancer cell population

scientific article published on 14 May 2019

The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus

scientific article

Trefoil factor 1 inhibits epithelial-mesenchymal transition of pancreatic intraepithelial neoplasm.

scientific article published on 23 July 2018

Tyrosine Phosphorylation of an Actin-Binding Protein Girdin Specifically Marks Tuft Cells in Human and Mouse Gut.

scientific article published in April 2017

Well-differentiated neuroendocrine tumor of the breast with extensive lymphatic and vascular infiltration

scientific article published on 11 November 2016

[Mechanisms for the differentiation of postnatal and adult neural stem cells: new insights and pathological issues based on the analysis of Girdin]

scientific article published on 01 June 2014

List of works by Atsushi Enomoto

A Case of Sialolithiasis in a Minor Salivary Gland of the Buccal Mucosa

A novel Drosophila Girdin-like protein is involved in Akt pathway control of cell size.

A rare pseudo tumour in the extraembryonic coelom in first trimester of pregnancy: ultrasound and pathology

ASC amino acid transporter 2, defined by enzyme-mediated activation of radical sources, enhances malignancy of GD2-positive small-cell lung cancer.

Aberrant Active cis-Regulatory Elements Associated with Downregulation of RET Finger Protein Overcome Chemoresistance in Glioblastoma

Accumulation of indoxyl sulfate in OAT1/3-positive tubular cells in kidneys of patients with chronic renal failure

Activation of c-Jun amino-terminal kinase by GDNF induces G2/M cell cycle delay linked with actin reorganization.

Adiponectin promotes migration activities of endothelial progenitor cells via Cdc42/Rac1

Akt-Girdin as oncotarget.

Akt-Girdin signaling in cancer-associated fibroblasts contributes to tumor progression.

Akt-dependent Girdin phosphorylation regulates repair processes after acute myocardial infarction

Akt/PKB regulates actin organization and cell motility via Girdin/APE

An inhibitor of advanced glycation end product formation reduces N epsilon-(carboxymethyl)lysine accumulation in glomeruli of diabetic rats.

Analysis of glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 expression in human diseased kidney.

Autoantibodies to transient receptor potential cation channel, subfamily M, member 1 in a Japanese patient with melanoma-associated retinopathy

Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse.

CD109 deficiency induces osteopenia with an osteoporosis-like phenotype in vivo

CD109 regulates in vivo tumor invasion in lung adenocarcinoma through TGF-β signaling

CD109: a multifunctional GPI-anchored protein with key roles in tumor progression and physiological homeostasis

Cancer-associated fibroblasts in gastrointestinal cancer

Cancer-associated fibroblasts that restrain cancer progression: Hypotheses and perspectives

Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress.

Chemerin promotes angiogenesis in vivo

Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion

Clinicopathological and Immunohistochemical Characteristics of Verruciform Xanthoma of the Lower Gingiva: A Case Report

Collective invasion of cancer: Perspectives from pathology and development

Complex roles of the actin-binding protein Girdin/GIV in DNA damage-induced apoptosis of cancer cells

Critical role of rabphilin-3A in the pathophysiology of experimental lymphocytic neurohypophysitis.

Cullin-associated NEDD8-dissociated protein 1, a novel interactor of rabphilin-3A, deubiquitylates rabphilin-3A and regulates arginine vasopressin secretion in PC12 cells

Cytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice

Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus.

Degeneration of retinal on bipolar cells induced by serum including autoantibody against TRPM1 in mouse model of paraneoplastic retinopathy

Dephosphorylation of Girdin by PP2A inhibits breast cancer metastasis

Desmin phosphorylation by Cdk1 is required for efficient separation of desmin intermediate filaments in mitosis and detected in murine embryonic/newborn muscle and human rhabdomyosarcoma tissues

Development of a method to preliminarily embed tissue samples using low melting temperature fish gelatin before sectioning: A technical note

Epidermal hyperplasia and appendage abnormalities in mice lacking CD109

Essential Role of Linx/Islr2 in the Development of the Forebrain Anterior Commissure.

Evaluation of osteopontin as a potential biomarker for central nervous system embryonal tumors.

Expression of Ret finger protein correlates with outcomes in endometrial cancer

Function and localization of urate transporter 1 in mouse kidney

Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules

GDNF-mediated signaling via RET tyrosine 1062 is essential for maintenance of spermatogonial stem cells.

Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain.

Girdin is phosphorylated on tyrosine 1798 when associated with structures required for migration

Girdin locates in centrosome and midbody and plays an important role in cell division ⬇️

Girdin maintains the stemness of glioblastoma stem cells.

Girdin phosphorylation is crucial for synaptic plasticity and memory: a potential role in the interaction of BDNF/TrkB/Akt signaling with NMDA receptor.

Girdin/GIV regulates collective cancer cell migration by controlling cell adhesion and cytoskeletal organization

Girdin/GIV regulates transendothelial permeability by controlling VE-cadherin trafficking through the small GTPase, R-Ras

High glucose impairs the proliferation and increases the apoptosis of endothelial progenitor cells by suppression of Akt.

High-fat diet feeding promotes stemness and precancerous changes in murine gastric mucosa mediated by leptin receptor signaling pathway.

Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins.

Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs.

IL-15 is elevated in the patients of postoperative enterocolitis

Identification of Meflin as a Potential Marker for Mesenchymal Stromal Cells

Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency.

Indoxyl Sulfate Downregulates Renal Expression of Klotho through Production of ROS and Activation of Nuclear Factor-ĸB ⬇️

Indoxyl sulfate promotes cardiac fibrosis with enhanced oxidative stress in hypertensive rats

Indoxyl sulfate promotes proliferation of human aortic smooth muscle cells by inducing oxidative stress.

Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress

Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NF-kappaB activation.

Indoxyl sulfate-induced activation of (pro)renin receptor is involved in expression of TGF-β1 and α-smooth muscle actin in proximal tubular cells.

Indoxyl sulphate induces oxidative stress and the expression of osteoblast-specific proteins in vascular smooth muscle cells.

Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.

Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors.

Interactions of human organic anion as well as cation transporters with indoxyl sulfate

Interactions of human organic anion transporters with diuretics.

Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine.

Interactions of urate transporter URAT1 in human kidney with uricosuric drugs ⬇️

Interleukin 15 activity in the rectal mucosa of inflammatory bowel disease.

Involvement of Girdin in the determination of cell polarity during cell migration

Metamorphosis of mesothelial cells with active horizontal motility in tissue culture

Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition

Molecular identification of a renal urate anion exchanger that regulates blood urate levels

Molecular mechanism linking BDNF/TrkB signaling with the NMDA receptor in memory: the role of Girdin in the CNS.

NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells ⬇️

Negative regulation of amino acid signaling by MAPK-regulated 4F2hc/Girdin complex.

New endoplasmic reticulum stress regulator, Gipie, regulates the survival of vascular smooth muscle cells and the neointima formation after vascular injury.

Nucleolin modulates the subcellular localization of GDNF-inducible zinc finger protein 1 and its roles in transcription and cell proliferation.