List of works - James Jester

A Comparative Study of Vertebrate Corneal Structure: The Evolution of a Refractive Lens

scientific article published on April 2015

A machine learning framework to analyze hyperspectral stimulated Raman scattering microscopy images of expressed human meibum.

scientific article published on 11 April 2017

A microfabricated, optically accessible device to study the effects of mechanical cues on collagen fiber organization.

scientific article

A novel immunofluorescent computed tomography (ICT) method to localise and quantify multiple antigens in large tissue volumes at high resolution

scientific article

A novel, long-lived, and highly engraftable immunodeficient mouse model of mucopolysaccharidosis type I.

scientific article published on 11 February 2015

A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure

scientific journal article

A role for NF-kappaB-dependent gene transactivation in sunburn.

scientific article published on June 2000

ALDH3A1 Plays a Functional Role in Maintenance of Corneal Epithelial Homeostasis

scientific article published on 11 January 2016

Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea.

scientific article

Absence of ductal hyper-keratinization in mouse age-related meibomian gland dysfunction (ARMGD).

scientific article published on November 2013

Adaptive effects of 30-night wear of hyper-O(2) transmissible contact lenses on bacterial binding and corneal epithelium: a 1-year clinical trial.

scientific article published on January 2002

An in vitro force measurement assay to study the early mechanical interaction between corneal fibroblasts and collagen matrix

scientific article published on 01 April 1997

Antioxidant function of corneal ALDH3A1 in cultured stromal fibroblasts.

scientific article

Application of second harmonic imaging microscopy to assess structural changes in optic nerve head structure ex vivo

scientific article

Assessing ocular irritation potential using a modified ex vivo rabbit eye test.

scientific article

Axial mechanical and structural characterization of keratoconus corneas

scientific article published on 26 May 2018

Bcl-2 and Bax regulation of corneal homeostasis in genetically altered mice.

scientific article

Bcl-2 expression in the human cornea

scientific article published on 01 August 2001

Behavioral responses of epidermal Langerhans cells in situ to local pathological stimuli.

scientific article published in April 2006

Castroviejo Lecture 2009: 40 years in search of the perfect contact lens

scientific article

Cell regulation of collagen fibril macrostructure during corneal morphogenesis

scientific article published on 29 August 2018

Characterization of expressed human meibum using hyperspectral stimulated Raman scattering microscopy

scientific article published on 11 October 2018

Characterization of quiescent epithelial cells in mouse meibomian glands and hair follicle/sebaceous glands by immunofluorescence tomography

scientific article

Collagen fiber crimping following in vivo UVA-induced corneal crosslinking

scientific article published on 14 August 2018

Confocal Microscopic Analysis of a Rabbit Eye Model of High-Incidence Recurrent Herpes Stromal Keratitis.

scientific article

Corneal aldehyde dehydrogenases: multiple functions and novel nuclear localization

scientific article

Corneal epithelial homeostasis following daily and overnight contact lens wear.

scientific article published on March 2002

Corneal haze after photorefractive keratectomy using different epithelial removal techniques: mechanical debridement versus laser scrape.

scientific article

Corneal haze development after PRK is regulated by volume of stromal tissue removal

scientific article published on 01 November 1998

Corneal haze phenotype in Aldh3a1-null mice: In vivo confocal microscopy and tissue imaging mass spectrometry.

scientific article

Corneal stromal wound healing in refractive surgery: the role of myofibroblasts.

scientific article

Custom built nonlinear optical crosslinking (NLO CXL) device capable of producing mechanical stiffening in ex vivo rabbit corneas

scientific article published on 29 September 2017

Development of a Langerhans cell-targeted gene therapy format using a dendritic cell-specific promoter.

scientific article

Direct correlation of collagen matrix deformation with focal adhesion dynamics in living corneal fibroblasts.

scientific article published on April 2003

Effect of cell migration on the maintenance of tension on a collagen matrix

scientific article published on 01 November 1999

Effect of desiccating stress on mouse meibomian gland function.

scientific article

Effects of Eyelid Closure and Disposable and Silicone Hydrogel Extended Contact Lens Wear on Rabbit Corneal Epithelial Proliferation ⬇️

scientific article published on May 1, 2003

Effects of age and dysfunction on human meibomian glands.

scientific article

Effects of daily and overnight wear of a novel hyper oxygen-transmissible soft contact lens on bacterial binding and corneal epithelium: a 13-month clinical trial.

scientific article published on November 2002

Effects of rigid and soft contact lens daily wear on corneal epithelium, tear lactate dehydrogenase, and bacterial binding to exfoliated epithelial cells.

scientific article

Elastic modulus and collagen organization of the rabbit cornea: epithelium to endothelium. ⬇️

scientific article

Evaluation of the corneal effects of topical ophthalmic fluoroquinolones using in vivo confocal microscopy.

scientific article

Evolution of the vertebrate corneal stroma

scientific article published in February 2018

Excess biglycan causes eyelid malformation by perturbing muscle development and TGF-alpha signaling

scientific journal article

Exertion of tractional force requires the coordinated up-regulation of cell contractility and adhesion

scientific article published on 01 January 1999

Extent of corneal injury as a biomarker for hazard assessment and the development of alternative models to the Draize rabbit eye test.

scientific article

Extent of initial corneal injury as a basis for alternative eye irritation tests.

scientific article published in April 2001

Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling.

scientific article published on 26 October 2007

From nano to macro: studying the hierarchical structure of the corneal extracellular matrix

scientific article

Frontiers of Ocular Surface Regenerative Medicine

scientific article published on 02 March 2016

Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection.

scientific article published on 2 May 2007

Hydrogen peroxide causes mitochondrial DNA damage in corneal epithelial cells.

scientific article published on May 2009

Immunofluorescence Tomography of Mouse Ocular Surface Epithelial Stem Cells and Their Niche Microenvironment

scientific article

In vivo confocal microscopy through-focusing to measure corneal flap thickness after laser in situ keratomileusis.

scientific article

In vivo fluorescent labeling of corneal wound healing fibroblasts

scientific article published on 01 March 2003

Inhibition of TGFBIp expression by lithium: implications for TGFBI-linked corneal dystrophy therapy.

scientific article

Internalization of Pseudomonas aeruginosa is mediated by lipid rafts in contact lens-wearing rabbit and cultured human corneal epithelial cells.

scientific article

Lessons in corneal structure and mechanics to guide the corneal surgeon

scientific article published on 01 September 2013

Light transmission/absorption characteristics of the meibomian gland

article

Lumican binds ALK5 to promote epithelium wound healing

scientific article (publication date: 2013)

Measurement of an Elasticity Map in the Human Cornea

scientific article

Measurement of corneal elasticity with an acoustic radiation force elasticity microscope.

scientific article

Measurement of corneal sublayer thickness and transparency in transgenic mice with altered corneal clarity using in vivo confocal microscopy

scientific article published on 01 January 2001

Meibocyte differentiation and renewal: Insights into novel mechanisms of meibomian gland dysfunction (MGD).

scientific article published on 17 February 2017

Meibomian gland dysfunction: hyperkeratinization or atrophy?

scientific article

Modulation of corneal fibroblast contractility within fibrillar collagen matrices.

scientific article published on November 2003

Modulation of cultured corneal keratocyte phenotype by growth factors/cytokines control in vitro contractility and extracellular matrix contraction

scientific article published on 01 November 2003

Myofibroblast Differentiation of Normal Human Keratocytes and hTERT, Extended-Life Human Corneal Fibroblasts ⬇️

scientific article published on May 1, 2003

Myofibroblast differentiation modulates keratocyte crystallin protein expression, concentration, and cellular light scattering.

scientific article published on 16 February 2012

Nanoscale topography-induced modulation of fundamental cell behaviors of rabbit corneal keratocytes, fibroblasts, and myofibroblasts.

scientific article

Neonatal corneal stromal development in the normal and lumican-deficient mouse.

scientific article

Nitrogen mustard-induced corneal injury involves the sphingomyelin-ceramide pathway.

scientific article published on 9 November 2017

Noninvasive corneal stromal collagen imaging using two-photon-generated second-harmonic signals.

scientific article

Nonlinear optical collagen cross-linking and mechanical stiffening: a possible photodynamic therapeutic approach to treating corneal ectasia.

scientific article

Nonlinear optical corneal collagen crosslinking of ex vivo rabbit eyes.

scientific article

Ocular aldehyde dehydrogenases: protection against ultraviolet damage and maintenance of transparency for vision.

scientific article published on 23 October 2012

Ocular surface alkali injury damages meibomian glands in mice.

scientific article published on 22 April 2017

Ocular surface inflammation impairs structure and function of meibomian gland.

scientific article

Organization of junctional proteins in proliferating cat corneal endothelium during wound healing.

scientific article

PPARγ Regulates Mouse Meibocyte Differentiation and Lipid Synthesis.

scientific article

PPARγ regulates meibocyte differentiation and lipid synthesis of cultured human meibomian gland epithelial cells (hMGEC)

scientific article published on 07 July 2018

Pathology of ocular irritation with acetone, cyclohexanol, parafluoroaniline, and formaldehyde in the rabbit low-volume eye test.

scientific article

Picosecond spectral coherent anti-Stokes Raman scattering imaging with principal component analysis of meibomian glands.

scientific article

Postnatal corneal transparency, keratocyte cell cycle exit and expression of ALDH1A1.

scientific article

Prolonged hypoxia induces lipid raft formation and increases Pseudomonas internalization in vivo after contact lens wear and lid closure.

scientific article published in May 2006

Pseudomonas aeruginosa corneal binding after 24-hour orthokeratology lens wear.

scientific article

Quantitative assessment of ophthalmic viscosurgical device retention using in vivo confocal microscopy.

scientific article published in December 2005

Quantitative characterization of acid- and alkali-induced corneal injury in the low-volume eye test.

scientific article

Recovery time of corneal epithelial proliferation in the rabbit following rigid gas-permeable extended contact-lens wear.

scientific article published on April 2003

Reducing peak corneal haze after photorefractive keratectomy in rabbits: prednisolone acetate 1.00% versus cyclosporine A 0.05%

scientific article

Regulation of Pseudomonas aeruginosa internalization after contact lens wear in vivo and in serum-free culture by ocular surface cells.

scientific article published in August 2006

Renewal of the Holocrine Meibomian Glands by Label-Retaining, Unipotent Epithelial Progenitors

scientific article published on 02 August 2016

Sensory nerve supports epithelial stem cell function in healing of corneal epithelium in mice: the role of trigeminal nerve transient receptor potential vanilloid 4

scientific article published on 09 November 2018

Special issue on meibomian glands.

scientific article published on 9 August 2017

Stromal wound healing explains refractive instability and haze development after photorefractive keratectomy: a 1-year confocal microscopic study.

scientific article published in July 2000

Successful treatment of the murine model of cystinosis using bone marrow cell transplantation.

scientific article

Synergistic Cysteamine Delivery Nanowafer as an Efficacious Treatment Modality for Corneal Cystinosis.

scientific article published on 29 August 2016

TGFbeta induced myofibroblast differentiation of rabbit keratocytes requires synergistic TGFbeta, PDGF and integrin signaling.

scientific article published in December 2002

TRPA1 is required for TGF-β signaling and its loss blocks inflammatory fibrosis in mouse corneal stroma.

scientific article published on 28 July 2014

The acetylcholine signaling network of corneal epithelium and its role in regulation of random and directional migration of corneal epithelial cells.

scientific article

The role of contact lens type, oxygen transmission, and care-related solutions in mediating epithelial homeostasis and pseudomonas binding to corneal cells: an overview.

scientific article published on November 2007

Three-dimensional distribution of transverse collagen fibers in the anterior human corneal stroma

scientific article

Transcriptome analysis after PPARγ activation in human meibomian gland epithelial cells (hMGEC)

scientific article published on 08 February 2019

Use of in vivo confocal microscopy to understand the pathology of accidental ocular irritation.

scientific article

Wakayama Symposium: Peroxisome proliferator-activated receptor-gamma (PPARγ) and meibomian gland dysfunction

scientific article published on 25 July 2012

List of works by James Jester

A Comparative Study of Vertebrate Corneal Structure: The Evolution of a Refractive Lens

A machine learning framework to analyze hyperspectral stimulated Raman scattering microscopy images of expressed human meibum.

A microfabricated, optically accessible device to study the effects of mechanical cues on collagen fiber organization.

A novel immunofluorescent computed tomography (ICT) method to localise and quantify multiple antigens in large tissue volumes at high resolution

A novel, long-lived, and highly engraftable immunodeficient mouse model of mucopolysaccharidosis type I.

A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure

A role for NF-kappaB-dependent gene transactivation in sunburn.

ALDH3A1 Plays a Functional Role in Maintenance of Corneal Epithelial Homeostasis

Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea.

Absence of ductal hyper-keratinization in mouse age-related meibomian gland dysfunction (ARMGD).

Adaptive effects of 30-night wear of hyper-O(2) transmissible contact lenses on bacterial binding and corneal epithelium: a 1-year clinical trial.

An in vitro force measurement assay to study the early mechanical interaction between corneal fibroblasts and collagen matrix

Antioxidant function of corneal ALDH3A1 in cultured stromal fibroblasts.

Application of second harmonic imaging microscopy to assess structural changes in optic nerve head structure ex vivo

Assessing ocular irritation potential using a modified ex vivo rabbit eye test.

Axial mechanical and structural characterization of keratoconus corneas

Bcl-2 and Bax regulation of corneal homeostasis in genetically altered mice.

Bcl-2 expression in the human cornea

Behavioral responses of epidermal Langerhans cells in situ to local pathological stimuli.

Castroviejo Lecture 2009: 40 years in search of the perfect contact lens

Cell regulation of collagen fibril macrostructure during corneal morphogenesis

Characterization of expressed human meibum using hyperspectral stimulated Raman scattering microscopy

Characterization of quiescent epithelial cells in mouse meibomian glands and hair follicle/sebaceous glands by immunofluorescence tomography

Collagen fiber crimping following in vivo UVA-induced corneal crosslinking

Confocal Microscopic Analysis of a Rabbit Eye Model of High-Incidence Recurrent Herpes Stromal Keratitis.

Corneal aldehyde dehydrogenases: multiple functions and novel nuclear localization

Corneal epithelial homeostasis following daily and overnight contact lens wear.

Corneal haze after photorefractive keratectomy using different epithelial removal techniques: mechanical debridement versus laser scrape.

Corneal haze development after PRK is regulated by volume of stromal tissue removal

Corneal haze phenotype in Aldh3a1-null mice: In vivo confocal microscopy and tissue imaging mass spectrometry.

Corneal stromal wound healing in refractive surgery: the role of myofibroblasts.

Custom built nonlinear optical crosslinking (NLO CXL) device capable of producing mechanical stiffening in ex vivo rabbit corneas

Development of a Langerhans cell-targeted gene therapy format using a dendritic cell-specific promoter.

Direct correlation of collagen matrix deformation with focal adhesion dynamics in living corneal fibroblasts.

Effect of cell migration on the maintenance of tension on a collagen matrix

Effect of desiccating stress on mouse meibomian gland function.

Effects of Eyelid Closure and Disposable and Silicone Hydrogel Extended Contact Lens Wear on Rabbit Corneal Epithelial Proliferation ⬇️

Effects of age and dysfunction on human meibomian glands.

Effects of daily and overnight wear of a novel hyper oxygen-transmissible soft contact lens on bacterial binding and corneal epithelium: a 13-month clinical trial.

Effects of rigid and soft contact lens daily wear on corneal epithelium, tear lactate dehydrogenase, and bacterial binding to exfoliated epithelial cells.

Elastic modulus and collagen organization of the rabbit cornea: epithelium to endothelium. ⬇️

Evaluation of the corneal effects of topical ophthalmic fluoroquinolones using in vivo confocal microscopy.

Evolution of the vertebrate corneal stroma

Excess biglycan causes eyelid malformation by perturbing muscle development and TGF-alpha signaling

Exertion of tractional force requires the coordinated up-regulation of cell contractility and adhesion

Extent of corneal injury as a biomarker for hazard assessment and the development of alternative models to the Draize rabbit eye test.

Extent of initial corneal injury as a basis for alternative eye irritation tests.

Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling.

From nano to macro: studying the hierarchical structure of the corneal extracellular matrix

Frontiers of Ocular Surface Regenerative Medicine

Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection.

Hydrogen peroxide causes mitochondrial DNA damage in corneal epithelial cells.

Immunofluorescence Tomography of Mouse Ocular Surface Epithelial Stem Cells and Their Niche Microenvironment

In vivo confocal microscopy through-focusing to measure corneal flap thickness after laser in situ keratomileusis.

In vivo fluorescent labeling of corneal wound healing fibroblasts

Inhibition of TGFBIp expression by lithium: implications for TGFBI-linked corneal dystrophy therapy.

Internalization of Pseudomonas aeruginosa is mediated by lipid rafts in contact lens-wearing rabbit and cultured human corneal epithelial cells.

Lessons in corneal structure and mechanics to guide the corneal surgeon

Light transmission/absorption characteristics of the meibomian gland

Lumican binds ALK5 to promote epithelium wound healing

Measurement of an Elasticity Map in the Human Cornea

Measurement of corneal elasticity with an acoustic radiation force elasticity microscope.

Measurement of corneal sublayer thickness and transparency in transgenic mice with altered corneal clarity using in vivo confocal microscopy

Meibocyte differentiation and renewal: Insights into novel mechanisms of meibomian gland dysfunction (MGD).

Meibomian gland dysfunction: hyperkeratinization or atrophy?

Modulation of corneal fibroblast contractility within fibrillar collagen matrices.

Modulation of cultured corneal keratocyte phenotype by growth factors/cytokines control in vitro contractility and extracellular matrix contraction

Myofibroblast Differentiation of Normal Human Keratocytes and hTERT, Extended-Life Human Corneal Fibroblasts ⬇️

Myofibroblast differentiation modulates keratocyte crystallin protein expression, concentration, and cellular light scattering.

Nanoscale topography-induced modulation of fundamental cell behaviors of rabbit corneal keratocytes, fibroblasts, and myofibroblasts.

Neonatal corneal stromal development in the normal and lumican-deficient mouse.

Nitrogen mustard-induced corneal injury involves the sphingomyelin-ceramide pathway.

Noninvasive corneal stromal collagen imaging using two-photon-generated second-harmonic signals.

Nonlinear optical collagen cross-linking and mechanical stiffening: a possible photodynamic therapeutic approach to treating corneal ectasia.

Nonlinear optical corneal collagen crosslinking of ex vivo rabbit eyes.

Ocular aldehyde dehydrogenases: protection against ultraviolet damage and maintenance of transparency for vision.

Ocular surface alkali injury damages meibomian glands in mice.

Ocular surface inflammation impairs structure and function of meibomian gland.

Organization of junctional proteins in proliferating cat corneal endothelium during wound healing.