List of works - Isabel Lastres-Becker

Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis.

scientific article

Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease.

scientific article

An overview of Parkinson's disease and the cannabinoid system and possible benefits of cannabinoid-based treatments.

scientific article published on January 2006

Ataxin-2 Modulates the Levels of Grb2 and Src but Not Ras Signaling ⬇️

scientific article published on January 19, 2013

Cannabinoid CB(1) receptors in the basal ganglia and motor response to activation or blockade of these receptors in parkin-null mice

scientific journal article

Cannabinoid CB2 Receptor Modulation by the Transcription Factor NRF2 is Specific in Microglial Cells

scientific article published on 05 August 2019

Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease.

scientific article published on August 2009

Cx3cr1-deficiency exacerbates alpha-synuclein-A53T induced neuroinflammation and neurodegeneration in a mouse model of Parkinson's disease.

scientific article

Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors.

scientific article

Endocannabinoids and basal ganglia functionality.

scientific article

Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis.

scientific article published on 25 November 2013

Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues.

scientific article published in May 2001

Increased cannabinoid CB1 receptor binding and activation of GTP-binding proteins in the basal ganglia of patients with Parkinson's syndrome and of MPTP-treated marmosets

scientific article (publication date: December 2001)

Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice.

scientific article

Involvement of vanilloid-like receptors in the effects of anandamide on motor behavior and nigrostriatal dopaminergic activity: in vivo and in vitro evidence.

scientific article published on May 2004

Loss of cannabinoid CB(1) receptors in the basal ganglia in the late akinetic phase of rats with experimental Huntington's disease

scientific article published on 01 November 2002

NRF2 and Primary Cilia: An Emerging Partnership

scientific article published on 02 June 2020

Nrf2 deficiency potentiates methamphetamine-induced dopaminergic axonal damage and gliosis in the striatum.

scientific article

Nrf2 protects the lung against inflammation induced by titanium dioxide nanoparticles: A positive regulator role of Nrf2 on cytokine release.

scientific article published on 26 February 2014

Nuclear import and export signals control the subcellular localization of Nurr1 protein in response to oxidative stress.

scientific article

Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy

scientific article

Pituitary adenylate cyclase-activating polypeptide stimulates glial fibrillary acidic protein gene expression in cortical precursor cells by activating Ras and Rap1.

scientific article published on 29 July 2008

Potential involvement of cannabinoid receptors in 3-nitropropionic acid toxicity in vivo.

scientific article published in October 2004

Role of MSK1 in the Induction of NF-κB by the Chemokine CX3CL1 in Microglial Cells

scientific article published on 04 March 2019

Role of microglial redox balance in modulation of neuroinflammation.

scientific article published on June 2009

Spinocerebellar ataxia 2 (SCA2).

scientific article published on January 2008

The endogenous cannabinoid system and the basal ganglia. biochemical, pharmacological, and therapeutic aspects.

scientific article

Transcription factors NRF2 and NF-κB are coordinated effectors of the Rho family, GTP-binding protein RAC1 during inflammation

scientific article

List of works by Isabel Lastres-Becker

Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis.

Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease.

An overview of Parkinson's disease and the cannabinoid system and possible benefits of cannabinoid-based treatments.

Ataxin-2 Modulates the Levels of Grb2 and Src but Not Ras Signaling ⬇️

Cannabinoid CB(1) receptors in the basal ganglia and motor response to activation or blockade of these receptors in parkin-null mice

Cannabinoid CB2 Receptor Modulation by the Transcription Factor NRF2 is Specific in Microglial Cells

Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease.

Cx3cr1-deficiency exacerbates alpha-synuclein-A53T induced neuroinflammation and neurodegeneration in a mouse model of Parkinson's disease.

Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors.

Endocannabinoids and basal ganglia functionality.

Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis.

Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues.

Increased cannabinoid CB1 receptor binding and activation of GTP-binding proteins in the basal ganglia of patients with Parkinson's syndrome and of MPTP-treated marmosets

Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice.

Involvement of vanilloid-like receptors in the effects of anandamide on motor behavior and nigrostriatal dopaminergic activity: in vivo and in vitro evidence.

Loss of cannabinoid CB(1) receptors in the basal ganglia in the late akinetic phase of rats with experimental Huntington's disease

NRF2 and Primary Cilia: An Emerging Partnership

Nrf2 deficiency potentiates methamphetamine-induced dopaminergic axonal damage and gliosis in the striatum.

Nrf2 protects the lung against inflammation induced by titanium dioxide nanoparticles: A positive regulator role of Nrf2 on cytokine release.

Nuclear import and export signals control the subcellular localization of Nurr1 protein in response to oxidative stress.

Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy

Pituitary adenylate cyclase-activating polypeptide stimulates glial fibrillary acidic protein gene expression in cortical precursor cells by activating Ras and Rap1.

Potential involvement of cannabinoid receptors in 3-nitropropionic acid toxicity in vivo.

Role of MSK1 in the Induction of NF-κB by the Chemokine CX3CL1 in Microglial Cells

Role of microglial redox balance in modulation of neuroinflammation.

Spinocerebellar ataxia 2 (SCA2).

The endogenous cannabinoid system and the basal ganglia. biochemical, pharmacological, and therapeutic aspects.

Transcription factors NRF2 and NF-κB are coordinated effectors of the Rho family, GTP-binding protein RAC1 during inflammation