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List of works by K H Kok

'One Health' for the people of Hong Kong and the world.

scientific article published on 12 December 2012

A novel bunyavirus causing fever and thrombocytopenia: More questions than answers ⬇️

scientific article published on November 1, 2011

A novel transcript isoform of STING that sequesters cGAMP and dominantly inhibits innate nucleic acid sensing.

scientific article published on 14 March 2018

An Epstein-Barr virus-encoded microRNA targets PUMA to promote host cell survival

scientific article

Antiviral activity of double-stranded RNA-binding protein PACT against influenza A virus mediated via suppression of viral RNA polymerase.

scientific article published on 7 March 2018

Broad-spectrum inhibition of common respiratory RNA viruses by a pyrimidine synthesis inhibitor with involvement of the host antiviral response

scientific article

CREB3 subfamily transcription factors are not created equal: Recent insights from global analyses and animal models.

scientific article published on 17 February 2011

CRISPR/Cas9-mediated genome editing of Epstein-Barr virus in human cells.

scientific article published on 12 December 2014

Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters

scientific article published on 07 October 2020

Comparative analysis of the activation of unfolded protein response by spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus HKU1.

scientific article published on 13 January 2014

Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza.

scientific article

Embryonic XMab21l2 expression is required for gastrulation and subsequent neural development.

scientific article published in February 2001

Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan

scientific article published on 28 January 2020

Group I p21-activated kinases facilitate Tax-mediated transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats.

scientific article

H7N9 influenza A virus activation of necroptosis in human monocytes links innate and adaptive immune responses

scientific article published on 05 June 2019

Human T-Cell Leukemia Virus Type 1 Infection and Adult T-Cell Leukemia.

scientific article published in January 2017

Human tryptophanyl-tRNA synthetase is an IFN-γ-inducible entry factor for Enterovirus

scientific article published on 15 October 2018

Identification and Validation of the Cellular Targets of Virus-Encoded MicroRNAs ⬇️

scientific article published on January 1, 2010

Inhibition of AIM2 inflammasome activation by a novel transcript isoform of IFI16

scientific article published on 13 August 2018

LKB1 tumor suppressor and salt-inducible kinases negatively regulate human T-cell leukemia virus type 1 transcription.

scientific article published on 11 April 2013

Loss of orf3b in the circulating SARS-CoV-2 strains

scientific article published on 18 November 2020

MIP-T3 Is a Negative Regulator of Innate Type I IFN Response ⬇️

scientific article published on November 11, 2011

Maternal cold inducible RNA binding protein is required for embryonic kidney formation in Xenopus laevis.

scientific article published in September 2000

Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response.

scientific article published on 12 February 2014

Mouse peroxiredoxin V is a thioredoxin peroxidase that inhibits p53-induced apoptosis

scientific article (publication date: 24 February 2000)

Mutagenesis and Genome Engineering of Epstein-Barr Virus in Cultured Human Cells by CRISPR/Cas9.

scientific article published on January 2017

PACT Facilitates RNA-Induced Activation of MDA5 by Promoting MDA5 Oligomerization.

scientific article

PACT- and RIG-I-Dependent Activation of Type I Interferon Production by a Defective Interfering RNA Derived from Measles Virus Vaccine

scientific article published on 25 November 2015

Perturbation of biogenesis and targeting of Epstein-Barr virus-encoded miR-BART3 microRNA by adenosine-to-inosine editing

scientific article published on 17 September 2013

Post-transcriptional suppression of gene expression in Xenopus embryos by small interfering RNA

scientific article published on April 2002

REV7 is required for anaphase-promoting complex-dependent ubiquitination and degradation of translesion DNA polymerase REV1.

scientific article

Receptor usage of a novel bat lineage C betacoronavirus reveals evolution of MERS-related coronavirus spike proteins for human DPP4 binding

scientific article published on 16 January 2018

Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins

scientific article published on 10 December 2018

Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins

scientific article published on 20 May 2018

Repurposing of Miltefosine as an Adjuvant for Influenza Vaccine

scientific article published on 11 December 2020

Requirement of CRTC1 coactivator for hepatitis B virus transcription

scientific article published on 9 October 2014

SMRT sequencing revealed the diversity and characteristics of defective interfering RNAs in influenza A (H7N9) virus infection.

scientific article published in January 2019

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

scientific article published in Nature Communications

Selective Activation of Type II Interferon Signaling by Zika Virus NS5 Protein

scientific article

Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex.

scientific article published on 20 April 2009

Suppression of PACT-induced type I interferon production by herpes simplex virus 1 Us11 protein.

scientific article published on 25 September 2013

Suppression of SARS-CoV-2 infection in ex-vivo human lung tissues by targeting class III phosphoinositide 3-kinase

scientific article published on 07 October 2020

Suppression of Type I Interferon Production by Human T-Cell Leukemia Virus Type 1 Oncoprotein Tax through Inhibition of IRF3 Phosphorylation.

scientific article published on 27 January 2016

Suppression of innate antiviral response by severe acute respiratory syndrome coronavirus M protein is mediated through the first transmembrane domain.

scientific article published on 10 February 2014

Suppression of type I and type III IFN signalling by NSs protein of severe fever with thrombocytopenia syndrome virus through inhibition of STAT1 phosphorylation and activation

scientific article

Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus as a Host-Targeting Antiviral Strategy

scientific article published on 17 January 2019

The double-stranded RNA-binding protein PACT functions as a cellular activator of RIG-I to facilitate innate antiviral response

scientific article published on 01 April 2011

Utility of Epstein-Barr virus-encoded small RNA promoters for driving the expression of fusion transcripts harboring short hairpin RNAs.

scientific article published on November 2007

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