List of works - Cheryl Hawkes

3D Reconstruction of the Neurovascular Unit Reveals Differential Loss of Cholinergic Innervation in the Cortex and Hippocampus of the Adult Mouse Brain

scientific article published on 04 July 2019

A Review of the Impact of Maternal Obesity on the Cognitive Function and Mental Health of the Offspring.

scientific article

A Simulation Model of Periarterial Clearance of Amyloid-β from the Brain

scientific article published on 12 February 2016

Afferent and efferent immunological pathways of the brain. Anatomy, function and failure.

scientific article

Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP + PS1 transgenic mouse brains.

scientific article

Amyloid and tau in the brain in sporadic Alzheimer's disease: defining the chicken and the egg.

scientific article published on 23 January 2014

Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer's disease.

scientific article published in October 2012

Are you also what your mother eats? Distinct proteomic portrait as a result of maternal high-fat diet in the cerebral cortex of the adult mouse

scientific article

Cerebrospinal fluid dynamics modulation by diet and cytokines in rats

scientific article published on 10 February 2020

Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways.

scientific article published on 12 May 2018

Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model.

scientific article

Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele

scientific article (publication date: 2012)

Effect of kainic acid treatment on insulin-like growth factor-2 receptors in the IGF2-deficient adult mouse brain.

scientific article published on 20 December 2006

Failure of perivascular drainage of β-amyloid in cerebral amyloid angiopathy

scientific article published in July 2014

Hypertension drives parenchymal β-amyloid accumulation in the brain parenchyma

scientific article

Immune complex formation impairs the elimination of solutes from the brain: implications for immunotherapy in Alzheimer's disease.

scientific article published on 9 August 2013

Increased Aβ pathology in aged Tg2576 mice born to mothers fed a high fat diet

scientific article published on 25 February 2016

Insulin-like growth factor-II/mannose-6-phosphate receptor: widespread distribution in neurons of the central nervous system including those expressing cholinergic phenotype

scientific journal article

Investigating the Lymphatic Drainage of the Brain: Essential Skills and Tools.

scientific article published in January 2017

Knockout of apolipoprotein A-I decreases parenchymal and vascular β-amyloid pathology in the Tg2576 mouse model of Alzheimer's disease

scientific article published on 14 May 2019

Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice

scientific article published on 07 January 2021

MK886 reduces cerebral amyloid angiopathy severity in TgCRND8 mice

scientific article published on 6 September 2013

Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

scientific article published on 23 January 2011

Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloid

scientific article

Pre- and Post-natal High Fat Feeding Differentially Affects the Structure and Integrity of the Neurovascular Unit of 16-Month Old Male and Female Mice

scientific article published on 02 October 2019

Prenatal high-fat diet alters the cerebrovasculature and clearance of β-amyloid in adult offspring

scientific article published on 7 January 2015

Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain.

scientific article

S1P Is Associated with Protection in Human and Experimental Cerebral Malaria ⬇️

scientific article published on May 5, 2011

Selective loss of basal forebrain cholinergic neurons by 192 IgG-saporin is associated with decreased phosphorylation of Ser glycogen synthase kinase-3beta.

scientific article published on October 2005

Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy.

scholarly article

Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway

scientific journal article

Single-transmembrane domain IGF-II/M6P receptor: potential interaction with G protein and its association with cholesterol-rich membrane domains.

scientific article published on 17 August 2012

Small molecule beta-amyloid inhibitors that stabilize protofibrillar structures in vitro improve cognition and pathology in a mouse model of Alzheimer's disease.

scientific article published on 13 January 2010

Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology. ⬇️

scientific article

Stroke-induced opposite and age-dependent changes of vessel-associated markers in co-morbid transgenic mice with Alzheimer-like alterations.

scientific article published on 5 October 2013

Synthesis of scyllo-inositol derivatives and their effects on amyloid beta peptide aggregation.

scientific article published on 26 June 2008

The evolutionarily conserved long non-coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms

scientific article published on 26 April 2021

The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system

scientific article (publication date: March 2004)

The role of perivascular innervation and neurally mediated vasoreactivity in the pathophysiology of Alzheimer's disease.

scientific article published on June 2017

Vascular basement membranes as pathways for the passage of fluid into and out of the brain

scientific article

White matter changes in dementia: role of impaired drainage of interstitial fluid.

scientific article

List of works by Cheryl Hawkes

3D Reconstruction of the Neurovascular Unit Reveals Differential Loss of Cholinergic Innervation in the Cortex and Hippocampus of the Adult Mouse Brain

A Review of the Impact of Maternal Obesity on the Cognitive Function and Mental Health of the Offspring.

A Simulation Model of Periarterial Clearance of Amyloid-β from the Brain

Afferent and efferent immunological pathways of the brain. Anatomy, function and failure.

Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP + PS1 transgenic mouse brains.

Amyloid and tau in the brain in sporadic Alzheimer's disease: defining the chicken and the egg.

Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer's disease.

Are you also what your mother eats? Distinct proteomic portrait as a result of maternal high-fat diet in the cerebral cortex of the adult mouse

Cerebrospinal fluid dynamics modulation by diet and cytokines in rats

Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways.

Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model.

Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele

Effect of kainic acid treatment on insulin-like growth factor-2 receptors in the IGF2-deficient adult mouse brain.

Failure of perivascular drainage of β-amyloid in cerebral amyloid angiopathy

Hypertension drives parenchymal β-amyloid accumulation in the brain parenchyma

Immune complex formation impairs the elimination of solutes from the brain: implications for immunotherapy in Alzheimer's disease.

Increased Aβ pathology in aged Tg2576 mice born to mothers fed a high fat diet

Insulin-like growth factor-II/mannose-6-phosphate receptor: widespread distribution in neurons of the central nervous system including those expressing cholinergic phenotype

Investigating the Lymphatic Drainage of the Brain: Essential Skills and Tools.

Knockout of apolipoprotein A-I decreases parenchymal and vascular β-amyloid pathology in the Tg2576 mouse model of Alzheimer's disease

Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice

MK886 reduces cerebral amyloid angiopathy severity in TgCRND8 mice

Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

Phosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloid

Pre- and Post-natal High Fat Feeding Differentially Affects the Structure and Integrity of the Neurovascular Unit of 16-Month Old Male and Female Mice

Prenatal high-fat diet alters the cerebrovasculature and clearance of β-amyloid in adult offspring

Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain.

S1P Is Associated with Protection in Human and Experimental Cerebral Malaria ⬇️

Selective loss of basal forebrain cholinergic neurons by 192 IgG-saporin is associated with decreased phosphorylation of Ser glycogen synthase kinase-3beta.

Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy.

Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway

Single-transmembrane domain IGF-II/M6P receptor: potential interaction with G protein and its association with cholesterol-rich membrane domains.

Small molecule beta-amyloid inhibitors that stabilize protofibrillar structures in vitro improve cognition and pathology in a mouse model of Alzheimer's disease.

Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology. ⬇️

Stroke-induced opposite and age-dependent changes of vessel-associated markers in co-morbid transgenic mice with Alzheimer-like alterations.

Synthesis of scyllo-inositol derivatives and their effects on amyloid beta peptide aggregation.

The evolutionarily conserved long non-coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms

The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system

The role of perivascular innervation and neurally mediated vasoreactivity in the pathophysiology of Alzheimer's disease.

Vascular basement membranes as pathways for the passage of fluid into and out of the brain

White matter changes in dementia: role of impaired drainage of interstitial fluid.