List of works by Alex Friedrich

A Comparison of Three Different Bioinformatics Analyses of the 16S-23S rRNA Encoding Region for Bacterial Identification

scientific article published in 2019

A European laboratory network for sequence-based typing of methicillin-resistant Staphylococcus aureus (MRSA) as a communication platform between human and veterinary medicine--an update on SeqNet.org

scientific article published on 8 May 2008

Abundance and Antimicrobial Resistance of Three Bacterial Species along a Complete Wastewater Pathway

scientific article published on 03 September 2019

Admission prevalence and acquisition of nasal carriage of meticillin-resistant Staphylococcus aureus (MRSA) in German rehabilitation centres

scientific article published on 25 March 2014

Algorithm for empirical glycopeptide treatment in patients with hematologic malignancies and enterococcus faecium blood stream infection

scientific article

Analysis of collection of hemolytic uremic syndrome-associated enterohemorrhagic Escherichia coli

scientific article

ArgO145, a Stx2a prophage of a bovine O145:H- STEC strain, is closely related to phages of virulent human strains.

scientific article

Assignment of Staphylococcus isolates to groups by spa typing, SmaI macrorestriction analysis, and multilocus sequence typing

scientific article published on July 2006

Author Correction: Critical steps in clinical shotgun metagenomics for the concomitant detection and typing of microbial pathogens

scholarly article published in Scientific Reports

Automated DNA sequence-based early warning system for the detection of methicillin-resistant Staphylococcus aureus outbreaks

scientific article

Bioinformatics in bacterial molecular epidemiology and public health: databases, tools and the next-generation sequencing revolution

scientific article (publication date: 2013)

Carbapenem-resistant Enterobacteriaceae in wildlife, food-producing, and companion animals: a systematic review.

scientific article published on 11 April 2018

Carbapenemase-producing Enterobacteriaceae in Europe: a survey among national experts from 39 countries, February 2013.

scientific article

Changing epidemiology of meticillin-resistant in 42 hospitals in the Dutch-German border region, 2012 to 2016: results of the search-and-follow-policy

article

Characteristics of hospital patients colonized with livestock-associated meticillin-resistant Staphylococcus aureus (MRSA) CC398 versus other MRSA clones

scientific article published on 22 October 2011

Chromosomal dynamism in progeny of outbreak-related sorbitol-fermenting enterohemorrhagic Escherichia coli O157:NM.

scientific article

Complete Coding Sequences of Five Dengue Virus Type 2 Clinical Isolates from Venezuela Obtained through Shotgun Metagenomics.

scientific article

Complete Genome Sequences of Two Methicillin-Resistant Staphylococcus haemolyticus Isolates of Multilocus Sequence Type 25, First Detected by Shotgun Metagenomics.

scientific article published on 5 April 2018

Comprehensive Molecular Characterization of Escherichia coli Isolates from Urine Samples of Hospitalized Patients in Rio de Janeiro, Brazil.

scientific article

Contact precautions in single-bed or multiple-bed rooms for patients with extended-spectrum β-lactamase-producing Enterobacteriaceae in Dutch hospitals: a cluster-randomised, crossover, non-inferiority study

scientific article published on 23 August 2019

Control of hospital acquired infections and antimicrobial resistance in Europe: the way to go

Core/Whole Genome Multilocus Sequence Typing and Core Genome SNP-Based Typing of OXA-48-Producing Klebsiella pneumoniae Clinical Isolates From Spain

scientific article published on 01 January 2019

Cost analysis of outbreaks with Methicillin-resistant Staphylococcus aureus (MRSA) in Dutch long-term care facilities (LTCF)

scientific article published in PLoS ONE

Cost-Analysis of Seven Nosocomial Outbreaks in an Academic Hospital

scientific article published on 10 February 2016

Cost-minimization model of a multidisciplinary antibiotic stewardship team based on a successful implementation on a urology ward of an academic hospital

scientific article published on 8 May 2015

Critical steps in clinical shotgun metagenomics for the concomitant detection and typing of microbial pathogens

scientific article published in Scientific Reports

Cross-border comparison of antibiotic prescriptions among children and adolescents between the north of the Netherlands and the north-west of Germany

scientific article published on 18 April 2016

Cross-border comparison of the Dutch and German guidelines on multidrug-resistant Gram-negative microorganisms

scientific article

Cross-border comparison of the admission prevalence and clonal structure of meticillin-resistant Staphylococcus aureus.

scientific article published on 6 February 2009

Cytolethal distending toxin in Escherichia coli O157:H7: spectrum of conservation, structure, and endothelial toxicity

scientific article

Detection of a novel mcr-5.4 gene variant in hospital tap water by shotgun metagenomic sequencing

scientific article published on 01 December 2019

Detection of in Water from Hospital Dental Chair Units and Molecular Characterization by Whole-Genome Sequencing

scientific article published on 18 July 2018

Determining the Virulence Properties of Escherichia coli ST131 Containing Bacteriocin-Encoding Plasmids Using Short- and Long-Read Sequencing and Comparing Them with Those of Other E. coli Lineages

scientific article published on 06 November 2019

Diagnosis of Shiga Toxin-Producing Escherichia ((ital.)) coli ((ital.)) Infections. Die Diagnostik von Shiga Toxin-produzierenden Escherichia coli-Infektionen

scientific article published in 2002

Diagnosis of Shiga Toxin-Producing Escherichia coli Infections/Die Diagnostik von Shiga Toxin-produzierenden Escherichia coli-Infektionen

scientific article published in 2002

Diagnosis of Shiga Toxin-Producing Escherichia coliInfections. Die Diagnostik von Shiga Toxin-produzierenden Escherichia coli-Infektionen

scientific article published in 2002

Differences in the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) among health-care workers using a “single” vs. “double” screening strategy

scientific article

Differential cytotoxic actions of Shiga toxin 1 and Shiga toxin 2 on microvascular and macrovascular endothelial cells.

scientific article published on 6 December 2010

Distribution of the urease gene cluster among and urease activities of enterohemorrhagic Escherichia coli O157 isolates from humans

scientific article

Dynamic modelling approaches for the analysis of the cost-effectiveness of seasonal influenza control.

scientific article published on 19 August 2016

EUREGIO MRSA-net Twente/Münsterland--a Dutch-German cross-border network for the prevention and control of infections caused by methicillin-resistant Staphylococcus aureus.

scientific article published on 28 August 2008

EUREGIO-Projekt MRSA-net Twente/Münsterland

scientific article published on 01 November 2006

Education in infection control: A need for European certification.

scientific article published on 09 September 2015

Elucidating vancomycin-resistant Enterococcus faecium outbreaks: the role of clonal spread and movement of mobile genetic elements

scientific article published on 01 December 2018

Emergence of pan-resistance in KPC-2 carbapenemase-producing Klebsiella pneumoniae in Crete, Greece: a close call

scientific article published on 26 January 2016

Escherichia coli O157 infections and unpasteurised milk

scientific article

Escherichia coli harboring Shiga toxin 2 gene variants: frequency and association with clinical symptoms

scientific article

Evaluation of the Xpert vanA/vanB assay using enriched inoculated broths for direct detection of vanB vancomycin-resistant Enterococci

scientific article published on 8 October 2014

Evidence-based infection control methods using spa genotyping for MRSA spread in hospitals

scientific article published in June 2005

Extensive colonization with carbapenemase-producing microorganisms in Romanian burn patients: infectious consequences from the Colectiv fire disaster

scientific article

Faecal S100A12 as a non-invasive marker distinguishing inflammatory bowel disease from irritable bowel syndrome

scientific article

Financial evaluations of antibiotic stewardship programs-a systematic review

scientific article

From Infection to Detection: Imaging S. aureus – host interactions

From theory to practice: molecular strain typing for the clinical and public health setting

scientific article published on 24 January 2013

Glycosphingolipids in vascular endothelial cells: relationship of heterogeneity in Gb3Cer/CD77 receptor expression with differential Shiga toxin 1 cytotoxicity

scientific article published on 5 January 2008

Hemolysin from Shiga toxin-negative Escherichia coli O26 strains injures microvascular endothelium

scientific article

High Prevalence of Infectious Diseases and Drug-Resistant Microorganisms in Asylum Seekers Admitted to Hospital; No Carbapenemase Producing Enterobacteriaceae until September 2015

scientific article

High interlaboratory reproducibility of DNA sequence-based typing of bacteria in a multicenter study

scientific article

Identification of a KPC-9-producing Klebsiella pneumoniae ST258 cluster among KPC-2-producing isolates of an ongoing outbreak in Northwestern Greece: a retrospective study.

scientific article published on 20 December 2017

Implementing an Euregional databasis webtool for transborder surveillance of notifiable infectious diseases.

scientific article published on 16 June 2015

In the centre of an epidemic: Fifteen years of LA-MRSA CC398 at the University Hospital Münster

scientific article

Incidence and risk factors for community-acquired acute gastroenteritis in north-west Germany in 2004.

scientific article published on 25 March 2009

Internal and External Validation of a Computer-Assisted Surveillance System for Hospital-Acquired Infections in a 754-Bed General Hospital in the Netherlands

scientific article

Latent introduction to the Netherlands of multiple antibiotic resistance including NDM-1 after hospitalisation in Egypt, August 2013.

scientific article

Marked Changes in Gut Microbiota in Cardio-Surgical Intensive Care Patients: A Longitudinal Cohort Study

scientific article published on 01 January 2019

Metagenomic Characterization of the Human Intestinal Microbiota in Fecal Samples from STEC-Infected Patients

scientific article published on 6 February 2018

Methicillin-resistant Staphylococcus aureus (MRSA): burden of disease and control challenges in Europe.

scientific article published on 14 October 2010

Meticillin-resistant Staphylococcus aureus (MRSA): global epidemiology and harmonisation of typing methods.

scientific article

Molecular Characterization of Staphylococcus aureus Isolates Transmitted between Patients with Buruli Ulcer

scientific article published on 11 September 2015

Molecular characterization and phylogeny of Shiga toxin-producing Escherichia coli isolates obtained from two Dutch regions using whole genome sequencing

scientific article published on 4 April 2016

Molecular epidemiology of meticillin-resistant Staphylococcus aureus (MRSA): think regionally but use globally uniform typing languages

scientific article published on 24 October 2013

New aspects in the pathogenesis of enteropathic hemolytic uremic syndrome

scientific article

New immuno-PCR assay for detection of low concentrations of shiga toxin 2 and its variants

scientific article published on 13 February 2008

New strains of community-acquired methicillin-resistant Staphylococcus aureus with Panton-Valentine leukocidin causing an outbreak of severe soft tissue infection in a football team.

scientific article

O035: Third federal state wide survey on MRSA management in North Rhine-Westphalian hospitals.

scientific article

O085: A network-based approach using intra-hospital patient transfers to identify high-risk wards during nosocomial outbreaks.

scientific article

Overview of molecular typing methods for outbreak detection and epidemiological surveillance.

scientific article published on 24 January 2013

P180: The value of real-time sequence based information in surveillance of nosocomial viral infections.

scientific article

P183: A multi-pronged approach to unravel rhinovirus transmission in a children’s hospital: towards effective infection control

scientific article

Persistence of nasal colonization with human pathogenic bacteria and associated antimicrobial resistance in the German general population

scientific article

Phylogeny and disease association of Shiga toxin-producing Escherichia coli O91.

scientific article

Phylogeny, clinical associations, and diagnostic utility of the pilin subunit gene (sfpA) of sorbitol-fermenting, enterohemorrhagic Escherichia coli O157:H-

scientific article published on October 2004

Prevalence and molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA) among pigs on German farms and import of livestock-related MRSA into hospitals.

scientific article published on 25 August 2009

Prevalence, virulence profiles, and clinical significance of Shiga toxin-negative variants of enterohemorrhagic Escherichia coli O157 infection in humans

scientific article

Prevention of Surgical Site Infections: A Systematic Review of Cost Analyses in the Use of Prophylactic Antibiotics

scientific article published on 18 July 2018

Promiscuous Shiga toxin 2e and its intimate relationship to Forssman.

scientific article published on 25 January 2012

Rapid detection of a norovirus pseudo-outbreak by using real-time sequence based information

scientific article published on 20 July 2013

Rapid identification and differentiation of clinical isolates of enteropathogenic Escherichia coli (EPEC), atypical EPEC, and Shiga toxin-producing Escherichia coli by a one-step multiplex PCR method

scientific article published on July 2006

Real-life data on antibiotic prescription and sputum culture diagnostics in acute exacerbations of COPD in primary care.

scientific article

Semi-selective broth improves screening for methicillin-resistant Staphylococcus aureus

scientific article published on 3 February 2010

SeqNet.org: a European laboratory network for sequence-based typing of microbial pathogens

scientific article published on 12 January 2006

Sequence-based typing of flaB is a more stable screening tool than typing of flaA for monitoring of Campylobacter populations

scientific article published on October 2004

Shiga toxin 1c-producing Escherichia coli strains: phenotypic and genetic characterization and association with human disease

scientific article

Shiga toxin activatable by intestinal mucus in Escherichia coli isolated from humans: predictor for a severe clinical outcome.

scientific article

Shiga toxin glycosphingolipid receptors in microvascular and macrovascular endothelial cells: differential association with membrane lipid raft microdomains

scientific article

Shiga toxin, cytolethal distending toxin, and hemolysin repertoires in clinical Escherichia coli O91 isolates

scientific article published on 29 April 2009

Shiga toxin-mediated hemolytic uremic syndrome: time to change the diagnostic paradigm?

scientific article

Shiga toxin-negative attaching and effacing Escherichia coli: distinct clinical associations with bacterial phylogeny and virulence traits and inferred in-host pathogen evolution.

scientific article

Sorbitol-fermenting enterohaemorrhagic Escherichia coli O157:H- causes another outbreak of haemolytic uraemic syndrome in children.

scientific article

Structural and functional differences between disease-associated genes of enterohaemorrhagic Escherichia coli O111.

scientific article

Systematic literature analysis and review of targeted preventive measures to limit healthcare-associated infections by meticillin-resistant Staphylococcus aureus.

scientific article published on 24 July 2014

The dynamic changes of dominant clones of Staphylococcus aureus causing bloodstream infections in the European region: results of a second structured survey

scientific article published on 11 December 2014

The molecular evolution of methicillin-resistant Staphylococcus aureus

scientific article published on March 2007

The mosaic genome structure and phylogeny of Shiga toxin-producing Escherichia coli O104:H4 is driven by short-term adaptation.

scientific article published on 27 December 2014

Transcriptional analysis of genes encoding Shiga toxin 2 and its variants in Escherichia coli

scientific article

Trends in regional outpatient antibiotic prescription data and interventions in the Dutch-German EURSAFETY HEALTH-NET-project

scientific article

Uncommon membrane distribution of Shiga toxin glycosphingolipid receptors in toxin-sensitive human glomerular microvascular endothelial cells

scientific article

Urease genes in non-O157 Shiga toxin-producing Escherichia coli: mostly silent but valuable markers for pathogenicity.

scientific article

Use of the multiple-locus variable-number tandem repeat fingerprinting method and microfluidic chips for rapid genotyping of Staphylococcus aureus isolates

scientific article

Virulence potential of Staphylococcus aureus isolates from Buruli ulcer patients

scientific article published on 19 April 2017

[EUREGIO MRSA-net Twente/Münsterland: "search & follow" by Euregional network building]

scientific article published on 23 November 2009

[Patient safety -- mission for the future: Healthcare-associated infections and antibiotic resistance]

scientific article published on 01 July 2014