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List of works by George P H Leung

14,15-Epoxyeicosatrienoic acid induces vasorelaxation through the prostaglandin EP(2) receptors in rat mesenteric artery.

scientific article published on 30 June 2010

A BK(Ca) to K(v) switch during spermatogenesis in the rat seminiferous tubules.

scientific article

A defective flexible loop contributes to the processing and gating defects of the predominant cystic fibrosis-causing mutation

scientific article published on 22 January 2019

A review of the pharmacological effects of Arctium lappa (burdock).

scientific article published on 28 October 2010

Acute simvastatin inhibits K ATP channels of porcine coronary artery myocytes

scientific article (publication date: 2013)

An andrographolide derivative AGP-26b exhibiting anti-angiogenic activity in HUVECs and zebrafish via blocking the VEGFA/VEGFR2 signaling pathway

scientific article published on 18 January 2017

Anti-Parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models?

scientific article published on 29 December 2011

Application of UPLC-MS/MS to simultaneously detect four bioactive compounds in the tumour-shrinking decoction (FM1523) for uterine fibroids treatment

scientific article published on 27 March 2019

Basal Flt1 tyrosine kinase activity is a positive regulator of endothelial survival and vascularization during zebrafish embryogenesis.

scientific article

Calycosin and Formononetin Induce Endothelium-Dependent Vasodilation by the Activation of Large-Conductance Ca2+-Activated K+ Channels (BKCa).

scientific article

Characterization of adenosine transport in H9c2 cardiomyoblasts.

scientific article published on 5 July 2006

Chemical and pharmacological evaluations on the extract of Scutellaria baicalensis Georgi (Huang-Qin) prepared by various extraction methods

scientific article

Co-expression of adrenomedullin and adrenomedullin receptors in rat epididymis: distinct physiological actions on anion transport.

scientific article published on 8 January 2003

Cytoprotection of baicalein against oxidative stress-induced cardiomyocytes injury through the Nrf2/Keap1 pathway.

scientific article

D-Glucose upregulates adenosine transport in cultured human aortic smooth muscle cells.

scientific article

Danshensu is the major marker for the antioxidant and vasorelaxation effects of Danshen (Salvia miltiorrhiza) water-extracts produced by different heat water-extractions ⬇️

scientific article published on September 29, 2012

Discovery of a ROCK inhibitor, FPND, which prevents cerebral hemorrhage through maintaining vascular integrity by interference with VE-cadherin

scientific article published on 21 August 2017

Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer's Disease Models In vitro and In vivo

scientific article published on 26 September 2018

Effect of thiazolidinediones on equilibrative nucleoside transporter-1 in human aortic smooth muscle cells.

scientific article published in August 2005

Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction

scientific article published on 02 July 2018

Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis.

scientific article published on 22 August 2013

Endothelium-dependent and -independent relaxation of rat aorta induced by extract of Schizophyllum commune.

scientific article published on 25 July 2014

Equilibrative Nucleoside Transporters 1 and 4: Which One Is a Better Target for Cardioprotection Against Ischemia-Reperfusion Injury?

scientific article published on June 2015

Expression of cystic fibrosis transmembrane conductance regulator in rat efferent duct epithelium.

scientific article published in May 2001

Expression of multiple Na+/H+ exchanger isoforms in cultured epithelial cells from rat efferent duct and cauda epididymidis.

scientific article

Expression of the cystic fibrosis transmembrane conductance regulator in rat spermatids: implication for the site of action of antispermatogenic agents.

scientific article

Extract of Scutellaria baicalensis Georgi Root Exerts Protection Against Myocardial Ischemia-Reperfusion Injury in Rats

scientific article published on 01 January 2011

Ficus virens proanthocyanidins induced apoptosis in breast cancer cells concomitantly ameliorated 5-fluorouracil induced intestinal mucositis in rats.

scientific article published on 10 October 2017

Folic acid supplementation modifies beta-adrenoceptor-mediated in vitro lipolysis of obese/diabetic (+db/+db) mice.

scientific article published on 13 July 2009

Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway

scientific article

Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways.

scientific article published on 30 June 2009

Functional analysis of site-directed glycosylation mutants of the human equilibrative nucleoside transporter-2

scientific article (publication date: March 2003)

Genistein potentiates protein kinase A activity in porcine coronary artery.

scientific article published on 30 December 2007

Genomic organization and functional characterization of the human concentrative nucleoside transporter-3 isoform (hCNT3) expressed in mammalian cells.

scientific article published on 18 September 2003

Iatrogenic mitochondriopathies: a recent lesson from nucleoside/nucleotide reverse transcriptase inhibitors.

scientific article published on January 2012

In vitro vitamin K(2) and 1α,25-dihydroxyvitamin D(3) combination enhances osteoblasts anabolism of diabetic mice.

scientific article published on 6 October 2015

Indazole inhibition of cystic fibrosis transmembrane conductance regulator Cl(-) channels in rat epididymal epithelial cells.

scientific article published in December 2002

Inhalable dry powder formulations of siRNA and pH-responsive peptides with antiviral activity against H1N1 influenza virus

scientific article

Inhibition of TNF‐α‐mediated endothelial cell–monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans‐3,5,4′‐trimethoxystilbene ⬇️

scientific article published on August 25, 2010

Inhibition of human equilibrative nucleoside transporters by 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine.

scientific article published on 4 July 2016

Inhibitory effects of epoxyeicosatrienoic acids on volume-activated chloride channels in rat mesenteric arterial smooth muscle.

scientific article published on 2 September 2008

Involvement of organic cation transporter-3 and plasma membrane monoamine transporter in serotonin uptake in human brain vascular smooth muscle cells.

scientific article

Kaempferol stimulates large conductance Ca2+ -activated K+ (BKCa) channels in human umbilical vein endothelial cells via a cAMP/PKA-dependent pathway

scientific article published on 19 May 2008

MECHANISMS UNDERLYING ACTION OF XINMAILONG INJECTION, A TRADITIONAL CHINESE MEDICINE IN CARDIAC FUNCTION IMPROVEMENT.

scientific article

Metabolism of calycosin, an isoflavone from Astragali Radix, in zebrafish larvae

article

Mitochondrial monoamine oxidase-A-mediated hydrogen peroxide generation enhances 5-hydroxytryptamine-induced contraction of rat basilar artery.

scientific article published on November 2010

Multiple ryanodine receptor subtypes and heterogeneous ryanodine receptor-gated Ca2+ stores in pulmonary arterial smooth muscle cells.

scientific article published on 29 April 2005

Na+‐H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3 ⬇️

scientific article published on December 1, 2001

Nongenomic effect of testosterone on chloride secretion in cultured rat efferent duct epithelia.

scientific article

Oleanolic Acid Loaded PEGylated PLA and PLGA Nanoparticles with Enhanced Cytotoxic Activity against Cancer Cells.

scientific article

One-step unidirectional cloning of tandem repeats of DNA fragments: an application for fusion protein production

scientific article published on 01 April 2002

Oridonin synergistically enhances the anti-tumor efficacy of doxorubicin against aggressive breast cancer via pro-apoptotic and anti-angiogenic effects

scientific article published on 13 June 2019

Physiological and pharmacological roles of vascular nucleoside transporters.

scientific article published on January 2012

Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms

scientific article published in 2023

Potentiation of EDHF-mediated relaxation by chloride channel blockers ⬇️

scientific article published on September 13, 2010

Pro-angiogenic effects of Ilexsaponin A1 on human umbilical vein endothelial cells in vitro and zebrafish in vivo

scientific article published on 7 October 2017

Proanthocyanidins from Uncaria rhynchophylla induced apoptosis in MDA-MB-231 breast cancer cells while enhancing cytotoxic effects of 5-fluorouracil.

scientific article

Regulation of Na+/H+ exchanger isoform 1 (NHE1) by calmodulin-binding sites: role of angiotensin II.

scientific article published on 29 October 2010

Relaxation effect of abacavir on rat basilar arteries.

scientific article published on 8 April 2015

Role of the nicotinic acetylcholine receptor α3 subtype in vascular inflammation

scientific article published on 29 August 2016

Serotonin via 5-HT1B and 5-HT2B receptors stimulates anion secretion in the rat epididymal epithelium

scientific article published on 01 September 1999

The role of mitochondrial and plasma membrane nucleoside transporters in drug toxicity.

scientific article published on October 2007

Uptake and protective effects of ergothioneine in human endothelial cells

scientific article published on 14 July 2014

VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation.

scientific article published on 16 September 2014

Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine.

scientific article

Vasodilatory effect of 14,15-epoxyeicosatrienoic acid on mesenteric arteries in hypertensive and aged rats.

scientific article published on 28 May 2014

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