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List of works by Joop A M J L Janssen

A new polymorphism in the type II deiodinase gene is associated with circulating thyroid hormone parameters.

scientific article published on 22 February 2005

A polymorphic CA repeat in the promoter region of the insulin-like growth factor-I (IGF-I) gene

scientific article published on 01 January 2003

A polymorphism in the IGF-I gene influences the age-related decline in circulating total IGF-I levels

scientific article published on 01 February 2003

A polymorphism in type I deiodinase is associated with circulating free insulin-like growth factor I levels and body composition in humans.

scientific article published on 13 October 2004

Absence or low IGF-1R-expression in esophageal adenocarcinoma is associated with tumor invasiveness and radicality of surgical resection.

scientific article published on 16 June 2015

Acute Effect of Pegvisomant on Cardiovascular Risk Markers in Healthy Men: Implications for the Pathogenesis of Atherosclerosis in GH Deficiency ⬇️

scientific article published on November 1, 2001

Addition of insulin glargine or NPH insulin to metformin monotherapy in poorly controlled type 2 diabetic patients decreases IGF-I bioactivity similarly ⬇️

scientific article published on January 10, 2012

Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity.

scientific article published in October 2004

Advantages and disadvantages of GH/IGF-I combination treatment.

scientific article published on 06 July 2008

An IGF-I gene polymorphism modifies the risk of developing persistent microalbuminuria in type 1 diabetes

article

An early diagnostic tool for diabetic peripheral neuropathy in rats

scientific article published on 18 May 2015

An igf-I gene polymorphism modifies the risk of diabetic retinopathy

scientific article published on 01 August 2006

An insulin-like growth factor-I promoter polymorphism is associated with increased mortality in subjects with myocardial infarction in an elderly Caucasian population

scientific article published on 10 March 2006

Association of the ER22/23EK polymorphism in the glucocorticoid receptor gene with survival and C-reactive protein levels in elderly men.

scientific article

Bioactive rather than total IGF-I is involved in acute responses to nutritional interventions in CAPD patients.

scientific article published on 9 November 2009

Blockade of the growth hormone (GH) receptor unmasks rapid GH-releasing peptide-6-mediated tissue-specific insulin resistance

scientific article published in February 2001

Building the Case for Insulin-Like Growth Factor Receptor-I Involvement in Thyroid-Associated Ophthalmopathy.

scientific article published on January 2016

Changes in circulating IGF1 receptor stimulating activity do not parallel changes in total IGF1 during GH treatment of GH-deficient adults

scientific article published on 6 May 2015

Circulating IgGs may modulate IGF-I receptor stimulating activity in a subset of patients with Graves' ophthalmopathy.

scientific article published on 7 January 2013

Circulating free insulin-like growth factor (IGF)-I, total IGF-I, and IGF binding protein-3 levels do not predict the future risk to develop prostate cancer: results of a case-control study involving 201 patients within a population-based screening

scientific article published on 01 September 2004

Circulating insulin-like growth factors may contribute substantially to insulin receptor isoform A and insulin receptor isoform B signalling.

scientific article published on 7 September 2012

Combined treatment for acromegaly with long-acting somatostatin analogs and pegvisomant: long-term safety for up to 4.5 years (median 2.2 years) of follow-up in 86 patients.

scientific article published on 13 January 2009

Concentrations of Insulin Glargine and Its Metabolites During Long-Term Insulin Therapy in Type 2 Diabetic Patients and Comparison of Effects of Insulin Glargine, Its Metabolites, IGF-I, and Human Insulin on Insulin and IGF-I Receptor Signaling ⬇️

scientific article published on 08 April 2013

Control of tumor size and disease activity during cotreatment with octreotide and the growth hormone receptor antagonist pegvisomant in an acromegalic patient

scientific article published in February 2001

Correction: An Early Diagnostic Tool for Diabetic Peripheral Neuropathy in Rats

scientific article published on 15 June 2015

Diagnosing metabolic syndrome in craniopharyngioma patients: body composition versus BMI

scientific article published on 01 August 2019

Disagreement in normative IGF-I levels may lead to different clinical interpretations and GH dose adjustments in GH deficiency.

scientific article published on 4 October 2017

Effect of Intensive Insulin Therapy on the Somatotropic Axis of Critically Ill Children

scientific article published on 01 June 2011

Effects of Somatostatin Analogs and Dopamine Agonists on Insulin-Like Growth Factor 2-Induced Insulin Receptor Isoform A Activation by Gastroenteropancreatic Neuroendocrine Tumor Cells

scientific article published on 2 February 2016

Effects of chronic slow release-lanreotide treatment on insulin-like growth factor system and metabolic parameters in acromegalic patients.

scientific article published on 31 May 2011

Effects of fasting and pegvisomant on the GH‐releasing hormone and GH‐releasing peptide‐6 stimulated growth hormone secretion ⬇️

scientific article published on October 1, 2001

Effects of the Renin-Angiotensin System Genes and Salt Sensitivity Genes on Blood Pressure and Atherosclerosis in the Total Population and Patients With Type 2 Diabetes

article

Efficacy and Safety of Switching to Pasireotide in Patients With Acromegaly Controlled With Pegvisomant and First-Generation Somatostatin Analogues (PAPE Study).

scientific article published on 15 November 2017

Efficacy and Safety of switching to Pasireotide in Acromegaly Patients controlled with Pegvisomant and Somatostatin Analogues: PAPE extension study

scientific article published on 12 October 2018

Efficacy and safety of bariatric surgery for craniopharyngioma-related hypothalamic obesity: a matched case–control study with 2 years of follow-up

scientific article published on 31 October 2016

Endocrine responses to ghrelin in adult patients with isolated childhood-onset growth hormone deficiency.

scientific article

Endogenous hormones and carotid atherosclerosis in elderly men.

scientific article

Fractures, Bone Mineral Density, and Final Height in Craniopharyngioma Patients with a Follow-up of 16 Years

scientific article published on 01 April 2020

Free and Total Insulin-Like Growth Factor I (IGF-I), IGF-Binding Protein-1 (IGFBP-1), and IGFBP-3 and Their Relationships to the Presence of Diabetic Retinopathy and Glomerular Hyperfiltration in Insulin-Dependent Diabetes Mellitus1 ⬇️

scientific article published on September 1, 1997

High IGFBP2 levels are not only associated with a better metabolic risk profile but also with increased mortality in elderly men.

scientific article published on 3 May 2012

High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control: the Rotterdam Study

scientific article published on 11 January 2013

How to Position Pasireotide LAR Treatment in Acromegaly

scientific article published on 01 June 2019

IGF-1 CA repeat variant and breast cancer risk in postmenopausal women

scientific article published on 11 June 2007

IGF-I Bioactivity Better Reflects Growth Hormone Deficiency than Total IGF-I ⬇️

scientific article published on May 11, 2011

IGF-I bioactivity might reflect different aspects of quality of life than total IGF-I in GH-deficient patients during GH treatment.

scientific article published on 7 January 2013

IGF-IR Targeted Therapy: Past, Present and Future

scientific article

Impact of Physical Exercise on Endocrine Aging

scientific article

Insulin analogs and cancer: a note of caution

scientific article

Insulin and its analogues and their affinities for the IGF1 receptor.

scientific article published on 05 September 2012

Insulin glargine is more potent in activating the human IGF-I receptor than human insulin and insulin detemir.

scientific article published on 4 November 2010

Insulin-like Growth Factor-I Receptor and Thyroid-Associated Ophthalmopathy

scientific article published on 01 February 2019

Insulin-like growth factor I: pros and cons of a bioassay.

scientific article

Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study)

scientific article published on 01 August 2004

Intravenous glucose administration in fasting rats has differential effects on acylated and unacylated ghrelin in the portal and systemic circulation: a comparison between portal and peripheral concentrations in anesthetized rats.

scientific article

Lack of associations between serum leptin, a polymorphism in the gene for the beta 3-adrenergic receptor and glucose tolerance in the Dutch population.

scientific article published in August 1998

Limited predictive value of an acute test with subcutaneous octreotide for long-term IGF-I normalization with Sandostatin LAR in acromegaly.

scientific article published in July 2005

Long-term efficacy and safety of combined treatment of somatostatin analogs and pegvisomant in acromegaly

scientific article published on 25 September 2007

Long-term efficacy and safety of pegvisomant in combination with long-acting somatostatin analogs in acromegaly

scientific article published on 17 June 2014

Low circulating insulin-like growth factor I bioactivity in elderly men is associated with increased mortality

scientific article published on 15 April 2008

Methylation of IGF2 regulatory regions to diagnose adrenocortical carcinomas

scientific article published in September 2016

Modifying Effects of Glucose and Insulin/Insulin-Like Growth Factors on Colon Cancer Cells

scientific article published on 05 July 2021

New Insights from IGF-IR Stimulating Activity Analyses: Pathological Considerations

scientific article published on 02 April 2020

Normal values of circulating insulin-like growth factor-I bioactivity in the healthy population: comparison with five widely used IGF-I immunoassays

scientific article published on 08 April 2008

Pasireotide responsiveness in acromegaly is mainly driven by somatostatin receptor subtype 2 expression

scientific article published on 01 March 2019

Postoperative evaluation of patients with acromegaly: clinical significance and timing of oral glucose tolerance testing and measurement of (free) insulin-like growth factor I, acid-labile subunit, and growth hormone-binding protein levels.

scientific article

Quality of life in acromegalic patients during long-term somatostatin analog treatment with and without pegvisomant.

scientific article published on 22 July 2008

Response to Krieger et al. re: "TSHR/IGF-1R Cross-Talk, Not IGF-1R Stimulating Antibodies, Mediates Graves' Ophthalmopathy Pathogenesis" (Thyroid 2017;27:746-747)

scientific article published on 28 September 2017

Serum free IGF-I, total IGF-I, IGFBP-1 and IGFBP-3 levels in an elderly population: relation to age and sex steroid levels.

scientific article published in April 1998

Somatostatin Receptor Expression in GH-Secreting Pituitary Adenomas Treated with Long-Acting Somatostatin Analogues in Combination with Pegvisomant.

scientific article published on 25 July 2016

The 'bio-assay' quality of life might be a better marker of disease activity in acromegalic patients than serum total IGF-I concentrations.

scientific article published in February 2005

The -Adducin Gene Is Associated With Macrovascular Complications and Mortality in Patients With Type 2 Diabetes

article

The IGSF1 deficiency syndrome: characteristics of male and female patients

scientific article

The insulin-like growth factor-I receptor stimulating activity (IRSA) in health and disease

scientific article published on 21 August 2019

The introduction of the IDS-iSYS total IGF-1 assay may have far-reaching consequences for diagnosis and treatment of GH deficiency.

scientific article published in January 2015

The metabolic syndrome and its components in 178 patients treated for craniopharyngioma after 16 years of follow-up.

scientific article published on 7 September 2017

Unacylated ghrelin acts as a potent insulin secretagogue in glucose-stimulated conditions

scientific article published on 19 June 2007

Unacylated ghrelin is active on the INS-1E rat insulinoma cell line independently of the growth hormone secretagogue receptor type 1a and the corticotropin releasing factor 2 receptor.

scientific article

Very long-term sequelae of craniopharyngioma.

scientific article

What is the efficacy of switching to weekly pegvisomant in acromegaly patients well controlled on combination therapy?

scientific article published on 22 February 2016

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