List of works - Young-Seuk Bae

2',5,7-Trihydroxy-4',5'-(2,2-dimethylchromeno)-8-(3-hydroxy-3-methylbutyl) flavanone purified from Cudrania tricuspidata induces apoptotic cell death of human leukemia U937 cells.

scientific article

Activation of ATP Binding for the Autophosphorylation of DosS, a Mycobacterium tuberculosis Histidine Kinase Lacking an ATP Lid Motif

scientific article

Apoptotic cell death through inhibition of protein kinase CKII activity by 3,4-dihydroxybenzaldehyde purified from Xanthium strumarium.

scientific article published on January 2008

CK2 Down-Regulation Increases the Expression of Senescence-Associated Secretory Phenotype Factors through NF-κB Activation

scientific article published on 02 January 2021

CK2 downregulation induces senescence-associated heterochromatic foci formation through activating SUV39h1 and inactivating G9a

scientific article published on 18 September 2018

Capsaicin, a component of red peppers, stimulates protein kinase CKII activity.

scientific article published in May 2010

Casein kinase II phosphorylates p34cdc2 kinase in G1 phase of the HeLa cell division cycle ⬇️

scientific article published on October 5, 1992

Characterization of protein interaction among subunits of protein kinase CKII in vivo and in vitro

scientific article published on February 28, 1998

Coumestrol induces senescence through protein kinase CKII inhibition-mediated reactive oxygen species production in human breast cancer and colon cancer cells.

scientific article published on 23 March 2013

Cudraflavanone A purified from Cudrania tricuspidata induces apoptotic cell death of human leukemia U937 cells, at least in part, through the inhibition of DNA topoisomerase I and protein kinase C activity.

scientific article published in October 2007

Cytotoxicity of diacetoxyscirpenol is associated with apoptosis by activation of caspase-8 and interruption of cell cycle progression by down-regulation of cdk4 and cyclin B1 in human Jurkat T cells.

scientific article

Defect of SIRT1-FoxO3a axis is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated cellular senescence and nematode aging

scientific article published on 01 April 2019

Development of FET-type albumin sensor for diagnosing nephritis.

scientific article

Downregulation of protein kinase CK2 activity induces age-related biomarkers in C. elegans.

scientific article

Downregulation of protein kinase CKII is associated with cellular senescence.

scientific article published on 19 January 2006

Erratum to: Suppression of c-Myc induces apoptosis via an AMPK/mTOR-dependent pathway by 4-O-methyl-ascochlorin in leukemia cells

scientific article published on 31 March 2016

Expression of connective tissue growth factor, a biomarker in senescence of human diploid fibroblasts, is up-regulated by a transforming growth factor-beta-mediated signaling pathway

scientific journal article

Fermented Acanthopanax koreanum Root Extract Reduces UVB- and H2O2-Induced Senescence in Human Skin Fibroblast Cells

scientific article

Global analysis of phosphoproteome dynamics in embryonic development of zebrafish (Danio rerio).

scientific article published on 9 October 2015

Identification of mutations in protein kinase CKIIbeta subunit that affect its binding to ribosomal protein L41 and homodimerization

scientific article published on 01 July 2003

In vivo AAV1 transduction with hRheb(S16H) protects hippocampal neurons by BDNF production

scientific article

Inactivation of the FoxO3a transcription factor is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated senescence in human colon cancer and breast cancer cells.

scientific article published on 25 July 2016

Inhibition of protein kinase CKII activity by euchrestaflavanone B purified from Cudrania tricuspidata.

scientific article

Inhibition of protein kinase CKII activity by resveratrol, a natural compound in red wine and grapes.

scientific article published in September 2002

Isothiocyanates inhibit the invasion and migration of C6 glioma cells by blocking FAK/JNK-mediated MMP-9 expression.

scientific article published on 18 September 2015

Mechanism underlying cytotoxicity of thialysine, lysine analog, toward human acute leukemia Jurkat T cells.

scientific article published in December 2003

Melittin has a chondroprotective effect by inhibiting MMP-1 and MMP-8 expressions via blocking NF-κB and AP-1 signaling pathway in chondrocytes.

scientific article published on 21 February 2015

Melittin suppresses EGF-induced cell motility and invasion by inhibiting PI3K/Akt/mTOR signaling pathway in breast cancer cells.

scientific article published on 25 March 2014

MiR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting α subunit of protein kinase CKII in human colorectal cancer cells.

scientific article published on 5 November 2012

Mitochondrial dysfunction induces the invasive phenotype, and cell migration and invasion, through the induction of AKT and AMPK pathways in lung cancer cells

scientific article published on 18 June 2018

Modulation of NADP(+)-dependent isocitrate dehydrogenase in aging.

scientific article

NADPH oxidase is involved in protein kinase CKII down-regulation-mediated senescence through elevation of the level of reactive oxygen species in human colon cancer cells.

scientific article published on 3 June 2010

Naringenin ameliorates kainic acid-induced morphological alterations in the dentate gyrus in a mouse model of temporal lobe epilepsy.

scientific article published on 31 August 2016

Over-expression of phospholipase D isozymes down-regulates protein kinase CKII activity via proteasome-dependent CKIIbeta degradation in NIH3T3 cells.

scientific article published on 19 March 2009

Phospholipase D2 downregulation induces cellular senescence through a reactive oxygen species-p53-p21Cip1/WAF1 pathway

scientific article published on 23 July 2014

Phosphorylation of CKBBP2/CRIF1 by protein kinase CKII promotes cell proliferation.

scientific article

Phosphorylation of ribosomal protein L5 by protein kinase CKII decreases its 5S rRNA binding activity.

scientific article

Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1

scientific article (publication date: August 2003)

Premature senescence in human breast cancer and colon cancer cells by tamoxifen-mediated reactive oxygen species generation.

scientific article published on 19 December 2013

Protein kinase C downregulation induces senescence via FoxO3a inhibition in HCT116 and HEK293 cells.

scientific article

Regulation of protein kinase CK2 catalytic activity by protein kinase C and phospholipase D2.

scientific article published on 15 December 2015

Regulation of protein kinase CKII by direct interaction with the C-terminal region of p47(phox).

scientific article

Role of phospholipase D in the lifespan of Caenorhabditis elegans.

scientific article

Silencing of the CKII alpha and CKII alpha' genes during cellular senescence is mediated by DNA methylation.

scientific article published on 6 November 2008

Suppression of c-Myc induces apoptosis via an AMPK/mTOR-dependent pathway by 4-O-methyl-ascochlorin in leukemia cells.

scientific article published on 27 February 2016

The C-terminal domain of PLD2 participates in degradation of protein kinase CKII β subunit in human colorectal carcinoma cells

scientific article published on 01 September 2011

The highly basic ribosomal protein L41 interacts with the beta subunit of protein kinase CKII and stimulates phosphorylation of DNA topoisomerase IIalpha by CKII.

scientific article

The p53-p21(Cip1/WAF1) pathway is necessary for cellular senescence induced by the inhibition of protein kinase CKII in human colon cancer cells.

scientific article

Thiol-linked peroxidase activity of human sensitive to apoptosis gene (SAG) protein

scientific article (publication date: 2002)

Upregulation of miR-760 and miR-186 is associated with replicative senescence in human lung fibroblast cells.

scientific article

p53 deacetylation by SIRT1 decreases during protein kinase CKII downregulation-mediated cellular senescence ⬇️

scientific article published on September 29, 2011

List of works by Young-Seuk Bae

2',5,7-Trihydroxy-4',5'-(2,2-dimethylchromeno)-8-(3-hydroxy-3-methylbutyl) flavanone purified from Cudrania tricuspidata induces apoptotic cell death of human leukemia U937 cells.

Activation of ATP Binding for the Autophosphorylation of DosS, a Mycobacterium tuberculosis Histidine Kinase Lacking an ATP Lid Motif

Apoptotic cell death through inhibition of protein kinase CKII activity by 3,4-dihydroxybenzaldehyde purified from Xanthium strumarium.

CK2 Down-Regulation Increases the Expression of Senescence-Associated Secretory Phenotype Factors through NF-κB Activation

CK2 downregulation induces senescence-associated heterochromatic foci formation through activating SUV39h1 and inactivating G9a

Capsaicin, a component of red peppers, stimulates protein kinase CKII activity.

Casein kinase II phosphorylates p34cdc2 kinase in G1 phase of the HeLa cell division cycle ⬇️

Characterization of protein interaction among subunits of protein kinase CKII in vivo and in vitro

Coumestrol induces senescence through protein kinase CKII inhibition-mediated reactive oxygen species production in human breast cancer and colon cancer cells.

Cudraflavanone A purified from Cudrania tricuspidata induces apoptotic cell death of human leukemia U937 cells, at least in part, through the inhibition of DNA topoisomerase I and protein kinase C activity.

Cytotoxicity of diacetoxyscirpenol is associated with apoptosis by activation of caspase-8 and interruption of cell cycle progression by down-regulation of cdk4 and cyclin B1 in human Jurkat T cells.

Defect of SIRT1-FoxO3a axis is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated cellular senescence and nematode aging

Development of FET-type albumin sensor for diagnosing nephritis.

Downregulation of protein kinase CK2 activity induces age-related biomarkers in C. elegans.

Downregulation of protein kinase CKII is associated with cellular senescence.

Erratum to: Suppression of c-Myc induces apoptosis via an AMPK/mTOR-dependent pathway by 4-O-methyl-ascochlorin in leukemia cells

Expression of connective tissue growth factor, a biomarker in senescence of human diploid fibroblasts, is up-regulated by a transforming growth factor-beta-mediated signaling pathway

Fermented Acanthopanax koreanum Root Extract Reduces UVB- and H2O2-Induced Senescence in Human Skin Fibroblast Cells

Global analysis of phosphoproteome dynamics in embryonic development of zebrafish (Danio rerio).

Identification of mutations in protein kinase CKIIbeta subunit that affect its binding to ribosomal protein L41 and homodimerization

In vivo AAV1 transduction with hRheb(S16H) protects hippocampal neurons by BDNF production

Inactivation of the FoxO3a transcription factor is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated senescence in human colon cancer and breast cancer cells.

Inhibition of protein kinase CKII activity by euchrestaflavanone B purified from Cudrania tricuspidata.

Inhibition of protein kinase CKII activity by resveratrol, a natural compound in red wine and grapes.

Isothiocyanates inhibit the invasion and migration of C6 glioma cells by blocking FAK/JNK-mediated MMP-9 expression.

Mechanism underlying cytotoxicity of thialysine, lysine analog, toward human acute leukemia Jurkat T cells.

Melittin has a chondroprotective effect by inhibiting MMP-1 and MMP-8 expressions via blocking NF-κB and AP-1 signaling pathway in chondrocytes.

Melittin suppresses EGF-induced cell motility and invasion by inhibiting PI3K/Akt/mTOR signaling pathway in breast cancer cells.

MiR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting α subunit of protein kinase CKII in human colorectal cancer cells.

Mitochondrial dysfunction induces the invasive phenotype, and cell migration and invasion, through the induction of AKT and AMPK pathways in lung cancer cells

Modulation of NADP(+)-dependent isocitrate dehydrogenase in aging.

NADPH oxidase is involved in protein kinase CKII down-regulation-mediated senescence through elevation of the level of reactive oxygen species in human colon cancer cells.

Naringenin ameliorates kainic acid-induced morphological alterations in the dentate gyrus in a mouse model of temporal lobe epilepsy.

Over-expression of phospholipase D isozymes down-regulates protein kinase CKII activity via proteasome-dependent CKIIbeta degradation in NIH3T3 cells.

Phospholipase D2 downregulation induces cellular senescence through a reactive oxygen species-p53-p21Cip1/WAF1 pathway

Phosphorylation of CKBBP2/CRIF1 by protein kinase CKII promotes cell proliferation.

Phosphorylation of ribosomal protein L5 by protein kinase CKII decreases its 5S rRNA binding activity.

Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1

Premature senescence in human breast cancer and colon cancer cells by tamoxifen-mediated reactive oxygen species generation.

Protein kinase C downregulation induces senescence via FoxO3a inhibition in HCT116 and HEK293 cells.

Regulation of protein kinase CK2 catalytic activity by protein kinase C and phospholipase D2.

Regulation of protein kinase CKII by direct interaction with the C-terminal region of p47(phox).

Role of phospholipase D in the lifespan of Caenorhabditis elegans.

Silencing of the CKII alpha and CKII alpha' genes during cellular senescence is mediated by DNA methylation.

Suppression of c-Myc induces apoptosis via an AMPK/mTOR-dependent pathway by 4-O-methyl-ascochlorin in leukemia cells.

The C-terminal domain of PLD2 participates in degradation of protein kinase CKII β subunit in human colorectal carcinoma cells

The highly basic ribosomal protein L41 interacts with the beta subunit of protein kinase CKII and stimulates phosphorylation of DNA topoisomerase IIalpha by CKII.

The p53-p21(Cip1/WAF1) pathway is necessary for cellular senescence induced by the inhibition of protein kinase CKII in human colon cancer cells.

Thiol-linked peroxidase activity of human sensitive to apoptosis gene (SAG) protein

Upregulation of miR-760 and miR-186 is associated with replicative senescence in human lung fibroblast cells.

p53 deacetylation by SIRT1 decreases during protein kinase CKII downregulation-mediated cellular senescence ⬇️