List of works - Marta Columbaro

A pathogenic mechanism leading to partial lipodistrophy and prospects for pharmacological treatment of insulin resistance syndrome

scientific article published on 01 January 2007

All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype.

scientific article published on 13 August 2015

Alterations of nuclear envelope and chromatin organization in mandibuloacral dysplasia, a rare form of laminopathy

scientific article published on 26 July 2005

Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning

scientific article published on 02 August 2019

Altered chromatin organization and SUN2 localization in mandibuloacral dysplasia are rescued by drug treatment.

scientific article

Altered expression of the MCSP/NG2 chondroitin sulfate proteoglycan in collagen VI deficiency

scientific article

Altered lipid metabolism could drive the bone marrow failure in fanconi anaemia

scientific article published on 12 March 2018

Altered pre-lamin A processing is a common mechanism leading to lipodystrophy.

scientific article published on 20 April 2005

Apoptosis and necrosis following exposure of U937 cells to increasing concentrations of hydrogen peroxide: the effect of the poly(ADP-ribose)polymerase inhibitor 3-aminobenzamide

scientific article published on 01 December 1999

Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria.

scientific article published on 19 October 2011

Chondrogenic differentiation of bone marrow concentrate grown onto a hylauronan scaffold: rationale for its use in the treatment of cartilage lesions.

scientific article

Collagen VI deficiency affects the organization of fibronectin in the extracellular matrix of cultured fibroblasts

article

Collagen VI myopathies: from the animal model to the clinical trial.

scientific article published on 06 January 2009

Compound Heterozygosity for Mutations inLMNAin a Patient with a Myopathic and Lipodystrophic Mandibuloacral Dysplasia Type A Phenotype

scientific article published on 11 September 2007

Concentration-dependent metabolic effects of metformin in healthy and Fanconi anemia lymphoblast cells.

scientific article

Diverse lamin-dependent mechanisms interact to control chromatin dynamics. Focus on laminopathies

scientific article

Doubly heterozygous LMNA and TTN mutations revealed by exome sequencing in a severe form of dilated cardiomyopathy

scientific article published on 06 March 2013

Drugs affecting prelamin A processing: effects on heterochromatin organization

scientific article

Dysferlin in a hyperCKaemic patient with caveolin 3 mutation and in C2C12 cells after p38 MAP kinase inhibition

scientific article (publication date: 31 December 2003)

Elevated TGF β2 serum levels in Emery-Dreifuss muscular dystrophy: implications for myocyte and tenocyte differentiation and fibrogenic processes.

scientific article

Emerin-prelamin A interplay in human fibroblasts

scientific article

Evaluation of energy metabolism and calcium homeostasis in cells affected by Shwachman-Diamond syndrome

scientific article published on 5 May 2016

Extracellular matrix and nuclear abnormalities in skeletal muscle of a patient with Walker-Warburg syndrome caused by POMT1 mutation

scientific article

Failure of lamin A/C to functionally assemble in R482L mutated familial partial lipodystrophy fibroblasts: altered intermolecular interaction with emerin and implications for gene transcription

scientific article published in November 2003

Functionalized Keratin as Nanotechnology-Based Drug Delivery System for the Pharmacological Treatment of Osteosarcoma ⬇️

scientific article published on 20 November 2018

H9c2 cardiac myoblasts undergo apoptosis in a model of ischemia consisting of serum deprivation and hypoxia: inhibition by PMA.

scientific article published on February 2003

Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses

article

Inhibition of Metalloproteinase Activity in FANCA Is Linked to Altered Oxygen Metabolism

scientific article published on 01 March 2015

Keratin nanoparticles co-delivering Docetaxel and Chlorin e6 promote synergic interaction between chemo- and photo-dynamic therapies

scientific article published on 19 August 2019

Lamin A/C sustains PcG protein architecture, maintaining transcriptional repression at target genes.

scientific article published on November 2015

Laminopathies: a chromatin affair

scientific article published on 18 July 2006

Lamins and bone disorders: current understanding and perspectives.

scientific article

Lamins are rapamycin targets that impact human longevity: a study in centenarians

scientific article published on 23 October 2013

Lineage-related susceptibility of human hemopoietic cell lines to apoptosis.

scientific article published on January 1999

Loss of SMPD4 Causes a Developmental Disorder Characterized by Microcephaly and Congenital Arthrogryposis

scientific article published on 05 September 2019

Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing

scientific article published on 2 December 2017

Mesenchymal stem cells from preterm to term newborns undergo a significant switch from anaerobic glycolysis to the oxidative phosphorylation

scientific article published on 3 October 2017

Mitochondrial dysfunction and apoptosis in myopathic mice with collagen VI deficiency.

scientific article published on 16 November 2003

Mitochondrial respiratory chain Complex I defects in Fanconi anemia complementation group A.

scientific article

Muscle ceroid lipofuscin-like deposits in a patient with corticobasal syndrome due to a progranulin mutation

scientific article published on 22 May 2017

Muscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organization

scientific article (publication date: September 2014)

Muscular laminopathies: role of prelamin A in early steps of muscle differentiation

scientific article published on 28 October 2010

Novel COL6A1 splicing mutation in a family affected by mild Bethlem myopathy

scientific article published on 01 April 2002

Nuclear alterations in autosomal-dominant Emery-Dreifuss muscular dystrophy

article published in 2001

Oct-1 recruitment to the nuclear envelope in adult-onset autosomal dominant leukodystrophy

scientific article published on 20 December 2012

Osteoblasts from a mandibuloacral dysplasia patient induce human blood precursors to differentiate into active osteoclasts

scientific article published on 16 March 2011

Phospholipid rearrangement of apoptotic membrane does not depend on nuclear activity

scientific article published on 01 November 1998

Pre-Lamin A processing is linked to heterochromatin organization.

scientific article published in December 2007

Prelamin A is involved in early steps of muscle differentiation.

scientific article

Prelamin A processing and heterochromatin dynamics in laminopathies.

scientific article published on 23 December 2006

Prelamin A-mediated recruitment of SUN1 to the nuclear envelope directs nuclear positioning in human muscle.

scientific article published on 11 February 2011

Programmed cell death in 2',3'-dideoxycytidine-resistant human monoblastoid U937 cells.

scientific article

Rapamycin treatment of Mandibuloacral dysplasia cells rescues localization of chromatin-associated proteins and cell cycle dynamics

scientific article

Rapid and efficient magnetization of mesenchymal stem cells by dendrimer-functionalized magnetic nanoparticles.

scientific article

Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment

scientific article published on November 2005

Samp1 Mislocalization in Emery-Dreifuss Muscular Dystrophy

scientific article published on 15 October 2018

Site-dependent differences in both prelamin A and adipogenic genes in subcutaneous adipose tissue of patients with type 2 familial partial lipodystrophy

article

The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells

scientific article

The empowerment of translational research: lessons from laminopathies.

scientific article

Treatment of FANCA cells with resveratrol and N-acetylcysteine: a comparative study

scientific article

Ultrastructural defects of collagen VI filaments in an Ullrich syndrome patient with loss of the alpha3(VI) N10-N7 domains

scientific article published on 01 January 2006

List of works by Marta Columbaro

A pathogenic mechanism leading to partial lipodistrophy and prospects for pharmacological treatment of insulin resistance syndrome

All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype.

Alterations of nuclear envelope and chromatin organization in mandibuloacral dysplasia, a rare form of laminopathy

Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning

Altered chromatin organization and SUN2 localization in mandibuloacral dysplasia are rescued by drug treatment.

Altered expression of the MCSP/NG2 chondroitin sulfate proteoglycan in collagen VI deficiency

Altered lipid metabolism could drive the bone marrow failure in fanconi anaemia

Altered pre-lamin A processing is a common mechanism leading to lipodystrophy.

Apoptosis and necrosis following exposure of U937 cells to increasing concentrations of hydrogen peroxide: the effect of the poly(ADP-ribose)polymerase inhibitor 3-aminobenzamide

Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria.

Chondrogenic differentiation of bone marrow concentrate grown onto a hylauronan scaffold: rationale for its use in the treatment of cartilage lesions.

Collagen VI deficiency affects the organization of fibronectin in the extracellular matrix of cultured fibroblasts

Collagen VI myopathies: from the animal model to the clinical trial.

Compound Heterozygosity for Mutations inLMNAin a Patient with a Myopathic and Lipodystrophic Mandibuloacral Dysplasia Type A Phenotype

Concentration-dependent metabolic effects of metformin in healthy and Fanconi anemia lymphoblast cells.

Diverse lamin-dependent mechanisms interact to control chromatin dynamics. Focus on laminopathies

Doubly heterozygous LMNA and TTN mutations revealed by exome sequencing in a severe form of dilated cardiomyopathy

Drugs affecting prelamin A processing: effects on heterochromatin organization

Dysferlin in a hyperCKaemic patient with caveolin 3 mutation and in C2C12 cells after p38 MAP kinase inhibition

Elevated TGF β2 serum levels in Emery-Dreifuss muscular dystrophy: implications for myocyte and tenocyte differentiation and fibrogenic processes.

Emerin-prelamin A interplay in human fibroblasts

Evaluation of energy metabolism and calcium homeostasis in cells affected by Shwachman-Diamond syndrome

Extracellular matrix and nuclear abnormalities in skeletal muscle of a patient with Walker-Warburg syndrome caused by POMT1 mutation

Failure of lamin A/C to functionally assemble in R482L mutated familial partial lipodystrophy fibroblasts: altered intermolecular interaction with emerin and implications for gene transcription

Functionalized Keratin as Nanotechnology-Based Drug Delivery System for the Pharmacological Treatment of Osteosarcoma ⬇️

H9c2 cardiac myoblasts undergo apoptosis in a model of ischemia consisting of serum deprivation and hypoxia: inhibition by PMA.

Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses

Inhibition of Metalloproteinase Activity in FANCA Is Linked to Altered Oxygen Metabolism

Keratin nanoparticles co-delivering Docetaxel and Chlorin e6 promote synergic interaction between chemo- and photo-dynamic therapies

Lamin A/C sustains PcG protein architecture, maintaining transcriptional repression at target genes.

Laminopathies: a chromatin affair

Lamins and bone disorders: current understanding and perspectives.

Lamins are rapamycin targets that impact human longevity: a study in centenarians

Lineage-related susceptibility of human hemopoietic cell lines to apoptosis.

Loss of SMPD4 Causes a Developmental Disorder Characterized by Microcephaly and Congenital Arthrogryposis

Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing

Mesenchymal stem cells from preterm to term newborns undergo a significant switch from anaerobic glycolysis to the oxidative phosphorylation

Mitochondrial dysfunction and apoptosis in myopathic mice with collagen VI deficiency.

Mitochondrial respiratory chain Complex I defects in Fanconi anemia complementation group A.

Muscle ceroid lipofuscin-like deposits in a patient with corticobasal syndrome due to a progranulin mutation

Muscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organization

Muscular laminopathies: role of prelamin A in early steps of muscle differentiation

Novel COL6A1 splicing mutation in a family affected by mild Bethlem myopathy

Nuclear alterations in autosomal-dominant Emery-Dreifuss muscular dystrophy

Oct-1 recruitment to the nuclear envelope in adult-onset autosomal dominant leukodystrophy

Osteoblasts from a mandibuloacral dysplasia patient induce human blood precursors to differentiate into active osteoclasts

Phospholipid rearrangement of apoptotic membrane does not depend on nuclear activity

Pre-Lamin A processing is linked to heterochromatin organization.

Prelamin A is involved in early steps of muscle differentiation.

Prelamin A processing and heterochromatin dynamics in laminopathies.

Prelamin A-mediated recruitment of SUN1 to the nuclear envelope directs nuclear positioning in human muscle.

Programmed cell death in 2',3'-dideoxycytidine-resistant human monoblastoid U937 cells.

Rapamycin treatment of Mandibuloacral dysplasia cells rescues localization of chromatin-associated proteins and cell cycle dynamics

Rapid and efficient magnetization of mesenchymal stem cells by dendrimer-functionalized magnetic nanoparticles.

Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment

Samp1 Mislocalization in Emery-Dreifuss Muscular Dystrophy

Site-dependent differences in both prelamin A and adipogenic genes in subcutaneous adipose tissue of patients with type 2 familial partial lipodystrophy

The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells

The empowerment of translational research: lessons from laminopathies.

Treatment of FANCA cells with resveratrol and N-acetylcysteine: a comparative study

Ultrastructural defects of collagen VI filaments in an Ullrich syndrome patient with loss of the alpha3(VI) N10-N7 domains