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List of works by Josep M. Argilés

A Rat Immobilization Model Based on Cage Volume Reduction: A Physiological Model for Bed Rest?

scientific article published on 29 March 2017

A differential pattern of gene expression in skeletal muscle of tumor-bearing rats reveals dysregulation of excitation–contraction coupling together with additional muscle alterations.

scientific article published in February 2014

A high fat diet in CF-1 mice: An experimental model for metabolic syndrome ⬇️

scientific article published on May 1, 2008

A multifactorial anti-cachectic approach for cancer cachexia in a rat model undergoing chemotherapy

scientific article

A new look at an old drug for the treatment of cancer cachexia: megestrol acetate.

scientific article published on 22 January 2013

A simple method for determining the rate of gastrointestinal transit in the rat ⬇️

scientific article published on 01 March 1993

Activation of UCPs gene expression in skeletal muscle can be independent on both circulating fatty acids and food intake. Involvement of ROS in a model of mouse cancer cachexia.

scientific article published in January 2005

Administration of tumor necrosis factor-alpha results in a decreased placental transfer of amino acids in the rat ⬇️

scientific article published on 01 August 1995

Anticachectic effects of formoterol: a drug for potential treatment of muscle wasting.

scientific article

Antiproteolytic effects of plasma from hibernating bears: a new approach for muscle wasting therapy?

scientific article

Apoptosis is present in skeletal muscle of cachectic gastro-intestinal cancer patients.

scientific article published on 3 August 2007

Are Peroxisome Proliferator-Activated Receptors Involved in Skeletal Muscle Wasting during Experimental Cancer Cachexia? Role of 2-Adrenergic Agonists

scientific article published on 01 July 2007

Autophagy Exacerbates Muscle Wasting in Cancer Cachexia and Impairs Mitochondrial Function

scientific article published on 28 May 2019

Beneficial immune modulatory effects of a specific nutritional combination in a murine model for cancer cachexia.

scientific article

Branched-chain amino acid catabolism and cancer cachexia (review) ⬇️

scientific article published on July 1, 1996

Branched-chain amino acids: a role in skeletal muscle proteolysis in catabolic states?

scientific article

Cachexia and sarcopenia: mechanisms and potential targets for intervention

scientific article published on 11 May 2015

Cachexia: a problem of energetic inefficiency.

scientific article published on 15 August 2014

Cancer cachexia, a clinical challenge.

scientific article published on 18 March 2019

Cancer cachexia: physical activity and muscle force in tumour-bearing rats

scientific article published on 01 January 2011

Cancer cachexia: understanding the molecular basis.

scientific article published on 09 October 2014

Cancer-associated malnutrition.

scientific article

Changes in lipid composition of plasma lipoproteins after total hepatectomy in the rat ⬇️

scientific article published on 01 December 1981

Combination of exercise training and erythropoietin prevents cancer-induced muscle alterations

scientific article published on 30 November 2015

Combined approach to counteract experimental cancer cachexia: eicosapentaenoic acid and training exercise

scientific article

Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) "cachexia-anorexia in chronic wasting diseases" and "nutrition in geriatrics"

scientific article

Conversion of leucine to β-hydroxy-β-methylbutyrate by α-keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes

scientific article

Counteracting inflammation: a promising therapy in cachexia.

scientific article published on January 2012

Cross-talk between skeletal muscle and adipose tissue: a link with obesity?

scientific article published in January 2005

Differences in food intake of tumour-bearing cachectic mice are associated with hypothalamic serotonin signalling

scientific article

Differential structural features in soleus and gastrocnemius of carnitine-treated cancer cachectic rats

scientific article published on 26 June 2019

Direct effects of doxorubicin on skeletal muscle contribute to fatigue.

scientific article published on 13 January 2009

Distinct behaviour of sorafenib in experimental cachexia-inducing tumours: the role of STAT3

scientific article

Dose-dependent effects of leucine supplementation on preservation of muscle mass in cancer cachectic mice.

scientific article published on 18 April 2011

Editorial: Biological Mechanism-Based and Patient-Centered Management of Cancer-Related Symptoms and Syndromes

scientific article published on 18 December 2018

Effects of CRF2R agonist on tumor growth and cachexia in mice implanted with Lewis lung carcinoma cells.

scientific article published on February 2008

Effects of Eicosapentaenoic Acid (EPA) Treatment on Insulin Sensitivity in an Animal Model of Diabetes: Improvement of the Inflammatory Status

scientific article published on 30 September 2010

Effects of IL-15 on rat brown adipose tissue: uncoupling proteins and PPARs

scientific journal article

Effects of formoterol on protein metabolism in myotubes during hyperthermia.

scientific article published on February 2011

Effects of the beta2 agonist formoterol on atrophy signaling, autophagy, and muscle phenotype in respiratory and limb muscles of rats with cancer-induced cachexia

scientific article published on 12 April 2018

Effects of the phosphodiesterase-IV inhibitor EMD 95832/3 on tumour growth and cachexia in rats bearing the Yoshida AH-130 ascites hepatoma.

scientific article published in December 2002

Emerging drugs for cancer cachexia.

scientific article published on November 2007

Ethanol and acetaldehyde concentrations in the rat foeto-maternal system after an acute ethanol administration given to the mother ⬇️

scientific article published on 01 December 1984

Experimental cancer cachexia: Evolving strategies for getting closer to the human scenario

scientific article published on 03 September 2015

Formoterol and cancer muscle wasting in rats: Effects on muscle force and total physical activity.

scientific article published on 28 April 2011

Formoterol attenuates increased oxidative stress and myosin protein loss in respiratory and limb muscles of cancer cachectic rats.

scientific article published on 13 December 2017

Formoterol treatment downregulates the myostatin system in skeletal muscle of cachectic tumour-bearing rats

scientific article published on 13 October 2011

Hypothalamic food intake regulation in a cancer-cachectic mouse model.

scientific article published on 13 November 2013

IGF-1 is downregulated in experimental cancer cachexia

scientific article published on 13 April 2006

Impaired voltage-gated K+ channel expression in brain during experimental cancer cachexia.

scientific article published in February 2003

Increased tumour necrosis factor‐α plasma levels during moderate-intensity exercise in COPD patients

scientific article published on 01 May 2003

Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia

scientific article published on 9 July 2012

Inter-tissue communication in cancer cachexia

scientific article published on 01 December 2018

Interleukin-15 affects differentiation and apoptosis in adipocytes: implications in obesity.

scientific article

Interleukin-15 increases glucose uptake in skeletal muscle. An antidiabetogenic effect of the cytokine.

scientific article published on 12 September 2006

Journey from cachexia to obesity by TNF ⬇️

scientific article published on August 1, 1997

Lipogenesis in rat tissues following carbohydrate refeeding: spleen lipogenesis is modulated by insulin

scientific article published on October 1, 1997

Mechanisms and treatment of cancer cachexia.

scientific article published on 30 June 2012

Mediators involved in the cancer anorexia-cachexia syndrome: past, present, and future.

scientific article

Mediators of cachexia in cancer patients

scientific article published on 29 March 2019

Metabolic effects of tumour necrosis factor-α on rat brown adipose tissue ⬇️

scientific article published on February 23, 1995

Metabolic host-tumor relationships during perinatal phase

scientific article published on June 28, 1997

Mice lacking TNFalpha receptors 1 and 2 are resistant to death and fulminant liver injury induced by agonistic anti-Fas antibody

scientific article published on 01 September 2003

Modulations of the calcineurin/NF-AT pathway in skeletal muscle atrophy.

scientific article published on 16 March 2007

Muscle wasting in cancer: the role of mitochondria.

scientific article published on May 2015

Myostatin blockage using actRIIB antagonism in mice bearing the Lewis lung carcinoma results in the improvement of muscle wasting and physical performance.

scientific article published on 8 November 2011

Myostatin: more than just a regulator of muscle mass ⬇️

scientific article published on February 10, 2012

Nonmuscle Tissues Contribution to Cancer Cachexia

scientific article

Novel approaches to the treatment of cachexia.

scientific article

Novel targeted therapies for cancer cachexia.

scientific article

Nuclear magnetic resonance in conjunction with functional genomics suggests mitochondrial dysfunction in a murine model of cancer cachexia

scientific article

Nutraceutical inhibition of muscle proteolysis: A role of diallyl sulphide in the treatment of muscle wasting

scientific article published on 22 July 2010

Open source in cachexia?

scientific article

Overexpression of UCP3 in both murine and human myotubes is linked with the activation of proteolytic systems: A role in muscle wasting?

scientific article published on 15 November 2005

Overexpression of interleukin-15 induces skeletal muscle hypertrophy in vitro: implications for treatment of muscle wasting disorders.

scientific article published on October 2002

Patterns of gene expression in muscle and fat in tumor-bearing rats: effects of CRF2R agonist on cachexia.

scientific article

Prevention of cancer and cardiovascular diseases: A common strategy? ⬇️

scientific article published on May 1, 1998

Prevention of liver cancer cachexia-induced cardiac wasting and heart failure

scientific article published on 29 August 2013

Protein breakdown on whole-body and organ level in non-cachectic tumour-bearing mice undergoing surgery

scientific article published on 21 May 2007

Redox balance and carbonylated proteins in limb and heart muscles of cachectic rats.

scientific article published in March 2010

Reduced protein degradation rates and low expression of proteolytic systems support skeletal muscle hypertrophy in transgenic mice overexpressing the c-ski oncogene

scientific article published on 01 October 2003

Request for regulatory guidance for cancer cachexia intervention trials.

scientific article

Resveratrol does not ameliorate muscle wasting in different types of cancer cachexia models

scientific article published on 29 January 2007

Resveratrol, a natural diphenol, reduces metastatic growth in an experimental cancer model.

scientific article published on 7 February 2006

Roles of skeletal muscle and peroxisome proliferator-activated receptors in the development and treatment of obesity.

scientific article

Sarcopenia with limited mobility: an international consensus

scientific article

Sequential changes in lipoprotein lipase activity and lipaemia induced by the Yoshida AH-130 ascites hepatoma in rats ⬇️

scientific article published on June 24, 1997

Short‐term effects of leptin on lipid metabolism in the rat ⬇️

scientific article published on July 24, 1998

Sirtuin 1 in skeletal muscle of cachectic tumour-bearing rats: a role in impaired regeneration?

scientific article

Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease

scientific article

Skeletal muscle mitochondrial uncoupling in a murine cancer cachexia model

article

TNF and pregnancy: the paradigm of a complex interaction ⬇️

scientific article published on September 1, 1997

TNF-alpha modulates cytokine and cytokine receptors in C2C12 myotubes

scientific article

TNFα expression of subcutaneous adipose tissue in obese and morbid obese females: relationship to adipocyte LPL activity and leptin synthesis

scientific article published on 01 May 2002

Targets in clinical oncology: the metabolic environment of the patient.

scientific article published on May 2007

The 2015 ESPEN Sir David Cuthbertson lecture: Inflammation as the driving force of muscle wasting in cancer.

scientific article

The AP-1/CJUN signaling cascade is involved in muscle differentiation: implications in muscle wasting during cancer cachexia.

scientific article published on 5 January 2006

The Three Faces of Sarcopenia

scientific article published on 05 May 2016

The animal cachexia score (ACASCO)

scientific article published on 16 September 2019

The assessment of productivity in biomedical research

scientific article published on 20 September 2016

The metabolic basis of cancer cachexia ⬇️

scientific article published on September 1, 1997

The metabolic fate of an oral 14C-alanine load in the obese Zucker rat

scientific article published on 01 March 1992

The pharmacological treatment of cachexia.

scientific article published on April 2004

The pivotal role of cytokines in muscle wasting during cancer.

scientific article

The potential of ghrelin in the treatment of cancer cachexia.

scientific article published on 18 October 2012

The role of cytokines in cancer cachexia

scientific article published on 01 December 2009

The systemic inflammatory response is involved in the regulation of K+channel expression in brain via TNF-α-dependent and -independent pathways

scientific article published on 01 August 2004

Theophylline is able to partially revert cachexia in tumour-bearing rats.

scientific article published on 21 August 2012

Therapeutic strategies against cancer cachexia

scientific article published on 01 January 2019

Training depletes muscle glutathione in patients with chronic obstructive pulmonary disease and low body mass index

scientific article published on 30 June 2006

Tumor Growth Influences Skeletal Muscle Protein Turnover in the Pregnant Rat ⬇️

scientific article published on 01 February 1998

Tumour necrosis factor-α does not cross the rat placenta ⬇️

scientific article published on June 5, 1998

Unifying diagnostic criteria for cachexia: An urgent need.

scientific article published on February 2017

Validation of the CAchexia SCOre (CASCO). Staging Cancer Patients: The Use of miniCASCO as a Simplified Tool.

scientific article published on 17 February 2017

Was tumour necrosis factor-α responsible for the fetal malformations associated with thalidomide in the early 1960s? ⬇️

scientific article published on April 1, 1998

l-Carnitine: An adequate supplement for a multi-targeted anti-wasting therapy in cancer

scientific article published on 19 May 2012

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