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List of works by Graham Rena

A simple method for sequencing small DNAs by introducing precise overlapping ends into restriction digestion fragments

scientific article published on August 1998

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

scientific article published on 14 July 2016

Biomolecular mode of action of metformin in relation to its copper binding properties.

scientific article published on 24 January 2014

Cellular responses to the metal-binding properties of metformin.

scientific article

D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a.

scientific article published on January 2004

Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology

scientific article published on 01 December 2018

Identification and characterization of the human homologue of the short PDE4A cAMP-specific phosphodiesterase RD1 (PDE4A1) by analysis of the human HSPDE4A gene locus located at chromosome 19p13.2

scientific article

In a cohort of individuals with type 2 diabetes using the drug sulfasalazine, HbA1c lowering is associated with haematological changes

scientific article published on 25 November 2020

Insulin Regulation of Insulin-like Growth Factor-binding Protein-1 Gene Expression Is Dependent on the Mammalian Target of Rapamycin, but Independent of Ribosomal S6 Kinase Activity ⬇️

scientific article published on January 9, 2002

Intracellular compartmentalization of PDE4 cyclic AMP-specific phosphodiesterases.

scientific article

Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug

scientific article

Metformin selectively targets redox control of complex I energy transduction

scientific article published on 26 August 2017

Molecular mechanism of action of metformin: old or new insights?

scientific article

New Evidence for the Mechanism of Action of a Type-2 Diabetes Drug Using a Magnetic Bead-Based Automated Biosensing Platform

scientific article published on 4 August 2017

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

scientific journal article

Receptor-mediated stimulation of lipid signalling pathways in CHO cells elicits the rapid transient induction of the PDE1B isoform of Ca2+/calmodulin-stimulated cAMP phosphodiesterase

scientific article

Regulation of hepatic glucose production and AMPK by AICAR but not by metformin depends on drug uptake through the equilibrative nucleoside transporter 1 (ENT1)

scientific article published on 02 August 2018

Repurposing Metformin for Cardiovascular Disease

scientific article

Salicylic acid: old and new implications for the treatment of type 2 diabetes?

scientific article published on 12 June 2014

The copper binding properties of metformin – QCM-D, XPS and nanobead agglomeration

scientific article published on 01 December 2015

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

scientific article

Upregulation of cAMP-specific PDE-4 activity following ligation of the TCR complex on thymocytes is blocked by selective inhibitors of protein kinase C and tyrosyl kinases

scientific article published on 01 January 1998

Zinc-dependent effects of small molecules on the insulin-sensitive transcription factor FOXO1a and gluconeogenic genes.

scientific article published on 19 November 2009

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