Search filters

List of works by Ilse Smolders

5-HTR and 5-HTR but not 5-HTR antagonism impairs the cross-modal reactivation of deprived visual cortex in adulthood

scientific article published on 06 November 2018

6 Hz corneal kindling in mice triggers neurobehavioral comorbidities accompanied by relevant changes in c-Fos immunoreactivity throughout the brain.

scientific article published on 20 November 2017

A companion to the preclinical common data elements for pharmacologic studies in animal models of seizures and epilepsy. A Report of the TASK3 Pharmacology Working Group of the ILAE/AES Joint Translational Task Force

scientific article published on 15 September 2018

AT1 Receptor Mediated Hypertensive Response to Ang II in the Nucleus Tractus Solitarii of Normotensive Rats Involves NO Dependent Local GABA Release

scientific article published on 03 May 2019

Absence of system xc- in mice decreases anxiety and depressive-like behavior without affecting sensorimotor function or spatial vision.

scientific article

Accelerated high-frequency repetitive transcranial magnetic stimulation enhances motor activity in rats.

scientific article published on 09 February 2017

Alterations in the motor cortical and striatal glutamatergic system and D-serine levels in the bilateral 6-hydroxydopamine rat model for Parkinson's disease.

scientific article published on 11 July 2015

Altered vesicular glutamate transporter expression in human temporal lobe epilepsy with hippocampal sclerosis

scientific article published on 7 February 2015

An improved microbore UHPLC method with electrochemical detection for the simultaneous determination of low monoamine levels in in vivo brain microdialysis samples

scientific article

An ultrasensitive nano UHPLC–ESI–MS/MS method for the quantification of three neuromedin-like peptides in microdialysates

scientific article published in March 2015

Ang II and Ang IV: unraveling the mechanism of action on synaptic plasticity, memory, and epilepsy

scientific article published on January 2008

Anticonvulsant and antiepileptogenic effects of system xc- inactivation in chronic epilepsy models

scientific article published on 09 June 2019

Anticonvulsant effect of a ghrelin receptor agonist in 6Hz corneally kindled mice

scientific article published on 5 July 2016

Are vesicular neurotransmitter transporters potential treatment targets for temporal lobe epilepsy?

scientific article published on 30 August 2013

Assessing mixtures of supercharging agents to increase the abundance of a specific charge state of Neuromedin U

scientific article published on 29 January 2019

Astrocytic Connexin43 Channels as Candidate Targets in Epilepsy Treatment

scientific article published on 20 November 2020

Astroglial CB1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory

scientific article published on 17 May 2018

Blood-brain barrier transport kinetics of the neuromedin peptides NMU, NMN, NMB and NT.

scientific article published on 31 March 2016

Brain and peripheral angiotensin II type 1 receptors mediate renal vasoconstrictor and blood pressure responses to angiotensin IV in the rat.

scientific article published in May 2008

Caloric Restriction Protects against Lactacystin-Induced Degeneration of Dopamine Neurons Independent of the Ghrelin Receptor.

scientific article published on 04 March 2017

Cellular targets for angiotensin II fragments: pharmacological and molecular evidence.

scientific article

Cerebral Cortical Circuitry Formation Requires Functional Glycine Receptors

scientific article

Challenges for the in vivo quantification of brain neuropeptides using microdialysis sampling and LC-MS.

scientific article

Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3

scientific article published on 11 August 2018

Combination of group I mGlu receptors antagonist with dopaminergic agonists strengthens the synaptic transmission at corticostriatal synapses in culture.

scientific article published on 23 March 2012

Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed

scientific article published on 23 October 2015

Cross-species pharmacological characterization of the allylglycine seizure model in mice and larval zebrafish.

scientific article

Deletion of insulin-regulated aminopeptidase in mice decreases susceptibility to pentylenetetrazol-induced generalized seizures ⬇️

scientific article published on May 25, 2011

Des-acyl ghrelin attenuates pilocarpine-induced limbic seizures via the ghrelin receptor and not the orexin pathway

scientific article

Development of potent and proteolytically stable human neuromedin U receptor agonists.

scientific article published on 14 December 2017

Disruption of the HPA-axis through corticosterone-release pellets induces robust depressive-like behavior and reduced BDNF levels in mice

scientific article published on 18 May 2016

Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.

scientific article

Effects of AT1 receptor antagonism on kainate-induced seizures and concomitant changes in hippocampal extracellular noradrenaline, serotonin, and dopamine levels in Wistar-Kyoto and spontaneously hypertensive rats

scientific article published on 23 April 2015

Effects of disrupted ghrelin receptor function on fear processing, anxiety and saccharin preference in mice

scientific article published on 06 September 2019

Effects of neuromedin U-8 on stress responsiveness and hypothalamus-pituitary-adrenal axis activity in male C57BL/6J mice

scientific article published on 02 March 2020

Erratum to "Selective Changes in Locomotor Activity in Mice Due to Low-intensity Microwaves Amplitude Modulated in the EEG Spectral Domain" [Neuroscience 359 (2017) 40-48]

scientific article published on 14 July 2018

GABAergic Signaling Mediates Central Cardiovascular Angiotensin II Type 2 Receptor Effects.

scientific article

Genetic and pharmacological manipulation of glial glutamate transporters does not alter infection-induced seizure activity

scientific article published on 22 April 2019

Genetic deletion of xCT attenuates peripheral and central inflammation and mitigates LPS-induced sickness and depressive-like behavior in mice.

scientific article

Ghrelin: an emerging new anticonvulsant neuropeptide.

scientific article published on 14 March 2012

High-affinity Na+/K+-dependent glutamate transporter EAAT4 is expressed throughout the rat fore- and midbrain.

scientific article published on November 2008

Higher-Density Culture in Human Embryonic Stem Cells Results in DNA Damage and Genome Instability.

scientific article published on 12 February 2016

Hypotensive Response to Angiotensin II Type 2 Receptor Stimulation in the Rostral Ventrolateral Medulla Requires Functional GABA-A Receptors

scientific article

Hypotensive and sympathoinhibitory responses to selective central AT2 receptor stimulation in spontaneously hypertensive rats

scientific article published on July 2015

IRAP and AT(1) receptor mediated effects of angiotensin IV.

scientific article published in March 2009

Identification of GSK-3 as a potential therapeutic entry point for epilepsy

article

Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.

scientific article published in December 2014

In-depth behavioral characterization of the corticosterone mouse model and the critical involvement of housing conditions.

scientific article published on 18 December 2015

In-vitro and in-vivo evaluation of the modulatory effects of the multitarget compound ASS234 on the monoaminergic system.

scientific article published on 30 January 2017

Inhibition of Connexin43 Hemichannels Impairs Spatial Short-Term Memory without Affecting Spatial Working Memory

scientific article published on 20 December 2016

Inhibition of astroglial connexin43 hemichannels with TAT-Gap19 exerts anticonvulsant effects in rodents.

scientific article published on 23 April 2018

LC-method development for the quantification of neuromedin-like peptides. Emphasis on column choice and mobile phase composition

scientific article published in April 2017

Monoaminergic Mechanisms in Epilepsy May Offer Innovative Therapeutic Opportunity for Monoaminergic Multi-Target Drugs

scientific article

Monoaminergic and Histaminergic Strategies and Treatments in Brain Diseases

scientific article

Neuromedin U and Structural Analogs: an Overview of Their Structure, Function and Selectivity

scientific article published on 16 September 2019

Neuropeptide FF receptors as novel targets for limbic seizure attenuation

scientific article published on 9 May 2015

Neuropeptide Y increases in vivo hippocampal extracellular glutamate levels through Y1 receptor activation.

scientific article published on 17 January 2012

Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synuclein

scientific article

Pharmacological Analysis of the Anti-epileptic Mechanisms of Fenfluramine in scn1a Mutant Zebrafish.

scientific article published on 06 April 2017

Reassessment of the antioxidative mixture for the challenging electrochemical determination of dopamine, noradrenaline and serotonin in microdialysis samples.

scientific article published on 2 July 2015

Renal vasoconstrictor and pressor responses to angiotensin IV in mice are AT1a-receptor mediated.

scientific article

Running Opposes the Effects of Social Isolation on Synaptic Plasticity and Transmission in a Rat Model of Depression.

scientific article

Selective changes in locomotor activity in mice due to low-intensity microwaves amplitude modulated in the EEG spectral domain.

scientific article

Sensitive targeted methods for brain metabolomic studies in microdialysis samples

scientific article published in November 2018

Serotonergic Modulation as Effective Treatment for Dravet Syndrome in a Zebrafish Mutant Model

scientific article

Side-by-side comparison of the effects of Gq- and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the hippocampal CA1

article by Yana Van Den Herrewegen et al published 20 September 2021 in Molecular Brain

Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model

scientific article published on 8 September 2017

Synthesis and in Vitro Evaluation of Stabilized and Selective Neuromedin U-1 Receptor Agonists

scientific article published on 23 April 2018

The Barnes Maze Task Reveals Specific Impairment of Spatial Learning Strategy in the Intrahippocampal Kainic Acid Model for Temporal Lobe Epilepsy

scientific article published on 10 August 2018

The effect of neuropeptide FF in the amygdala kindling model.

scientific article

Trans-Modulation of the Somatostatin Type 2A Receptor Trafficking by Insulin-Regulated Aminopeptidase Decreases Limbic Seizures.

scientific article

Validation of the 6 Hz refractory seizure mouse model for intracerebroventricularly administered compounds.

scientific article published on 6 June 2015

Zonisamide attenuates lactacystin-induced parkinsonism in mice without affecting system xc.

scientific article

Paulina is supported by:

About Paulina

Help