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List of works by Cheng-Wei Tom Chang

Advances in the development of connexin hemichannel inhibitors selective toward Cx43

scientific article published on 05 January 2021

Antifungal Amphiphilic Aminoglycosides

scientific article

Antifungal amphiphilic aminoglycoside K20: bioactivities and mechanism of action

scientific article

Antifungal amphiphilic kanamycins: new life for an old drug

scientific article published on 17 April 2018

Cationic Anthraquinone Analogs as Selective Antimicrobials.

scientific article published on 20 May 2019

Characterization of Three Tailoring Enzymes in Dutomycin Biosynthesis and Generation of a Potent Antibacterial Analogue.

scientific article published on 19 May 2016

Convenient divergent synthesis of a library of trehalosamine analogues.

scientific article

Cyclopamine: from cyclops lambs to cancer treatment.

scientific article published on 22 April 2014

Design and synthesis of pyrankacin: a pyranmycin class of broad-spectrum aminoglycoside antibiotic.

scientific article

Development of Fungal Selective Amphiphilic Kanamycin: Cost-Effective Synthesis and Use of Fluorescent Analogs for Mode of Action Investigation

scientific article published on 20 February 2019

Development of a monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and KAAD-cyclopamine.

scientific article published on 29 March 2012

Divergent Synthesis of Three Classes of Antifungal Amphiphilic Kanamycin Derivatives

scientific article published on 18 October 2016

Exploring the optimal site for modifications of pyranmycins with the extended arm approach.

scientific article

In vitro antifungal synergy between amphiphilic aminoglycoside K20 and azoles against Candida species and Cryptococcus neoformans

scientific article published on 10 August 2015

Inhibition of Connexin Hemichannels by New Amphiphilic Aminoglycosides without Antibiotic Activity

scientific article published on 19 June 2018

Investigation of antibacterial mode of action for traditional and amphiphilic aminoglycosides.

scientific article

Investigation of the regioselectivity for the staudinger reaction and its application for the synthesis of aminoglycosides with N-1 modification.

scientific article published on 28 April 2007

Library synthesis and antibacterial investigation of cationic anthraquinone analogs.

scientific article

Membrane lipid-modulated mechanism of action and non-cytotoxicity of novel fungicide aminoglycoside FG08.

scientific article

Mesobiliverdin IXα Enhances Rat Pancreatic Islet Yield and Function.

scientific article published on 23 April 2013

Mode of action investigation for the antibacterial cationic anthraquinone analogs

scientific article published on 31 August 2011

Predictable enzymatic glycosylation

scientific article published on 01 June 2009

Pyranmycins, a novel class of aminoglycosides with improved acid stability: the SAR of D-pyranoses on ring III of pyranmycin.

scientific article published on December 2002

Relative toxicities and neuromuscular nicotinic receptor agonistic potencies of anabasine enantiomers and anabaseine

scientific article

Reversal of the apparent regiospecificity of NAD(P)H-dependent hydride transfer: the properties of the difluoromethylene group, a carbonyl mimic.

scientific article

Safe and easy route for the synthesis of 1,3-dimethyl-1,2,3-triazolium salt and investigation of its anticancer activities.

scientific article published on 26 August 2013

Scalable and cost-effective tosylation-mediated synthesis of antifungal and fungal diagnostic 6″-Modified amphiphilic kanamycins

scientific article published on 22 August 2019

Separation and measurement of plant alkaloid enantiomers by RP-HPLC analysis of their Fmoc-Alanine analogs.

scientific article published in September 2008

Sonication-assisted library synthesis of oxazolidinone-carbohydrate conjugates.

scientific article

Sonication-assisted oligomannoside synthesis

scientific article published on 01 January 2009

Sonochemistry: a powerful way of enhancing the efficiency of carbohydrate synthesis

scientific article published on 01 July 2006

Stereoselective potencies and relative toxicities of γ-coniceine and N-methylconiine enantiomers.

scientific article published on 2 April 2013

Structure-activity relationships for antibacterial to antifungal conversion of kanamycin to amphiphilic analogues.

scientific article published on 13 April 2015

Surprising alteration of antibacterial activity of 5"-modified neomycin against resistant bacteria.

scientific article published on December 2008

Synthesis and antibacterial activity study of a novel class of cationic anthraquinone analogs

scientific article published on 04 November 2010

Synthesis and anticancer structure activity relationship investigation of cationic anthraquinone analogs.

scientific article published on 28 February 2014

Synthesis and bioactivity investigation of quinone-based dimeric cationic triazolium amphiphiles selective against resistant fungal and bacterial pathogens.

scientific article published on 5 December 2016

Synthesis and combinational antibacterial study of 5''-modified neomycin.

scientific article

Synthesis of TDP-3-amino-3,4,6-trideoxy-alpha-D-xylo-hexopyranose--the immediate precursor of TDP-alpha-D-desosamine.

scientific article published in June 2002

Synthesis of novel aminoglycosides via allylic azide rearrangement for investigating the significance of 2'-amino group.

scientific article published on 15 January 2010

Three new fusidic acid derivatives and their antibacterial activity.

scientific article published on 20 March 2015

Tuning the biological activity of cationic anthraquinone analogues specifically toward Staphylococcus aureus

scientific article published on 06 August 2018