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List of works by Oded Sperling

"Flipped" lactic dehydrogenase pattern in acute coronary insufficiency

scientific article published on 01 December 1986

A case of Lasch--Nyhan syndrome (total deficiency of hypoxanthine-guanine phosphoribosyltransferase)

scientific article published on 01 May 1972

A novel point mutation (I137T) in the conserved 5-phosphoribosyl-1-pyrophosphate binding motif of hypoxanthine-guanine phosphoribosyltransferase (HPRTJerusalem) in a variant of Lesch-Nyhan syndrome

scientific article

AMP catabolism in primary rat cardiomyocyte cultures

scientific article published on 01 January 1989

Abnormal property of human mutant hypoxanthine-guanine phosphoribosyltransferase: insensitivity of fibroblast enzyme to stabilization against freezing and thawing by 5-phosphoribosyl-1-pyrophosphate

scientific article published on 01 February 1974

Abnormal purine and pyrimidine nucleotide content in primary astroglia cultures from hypoxanthine-guanine phosphoribosyltransferase-deficient transgenic mice

scientific journal article

Abnormality in renal urate handling in the syndrome of inappropriate secretion of antidiuretic hormone

scientific article published on 01 June 1982

Accelerated erythrocyte 5-phosphoribosyl-1-pyrophosphate synthesis. A familial abnormality associated with excessive uric acid production and gout

scientific article published on 01 August 1972

Acceleration of purine synthesis in mouse liver by glycogenolytic hormones ⬇️

scientific article published on 01 October 1991

Activity of adenosine deaminase and of purine nucleoside phosphorylase in peripheral lymphocytes from patients with acquired immunological disorders

scientific article published on 01 April 1980

Adenine nucleotide metabolism in primary rat neuronal cultures

scientific article

Adenosine deaminase activity in lymphocyte subpopulations of B-16 melanoma and normal C57BL bearing mice

scientific article published on 01 January 1984

Adenosine-Induced Preconditioning of Rat Neuronal Cultures Against Ischemia-Reperfusion Injury ⬇️

scientific article published on January 1, 1998

Allopurinol in the prophylaxis of uric acid stones

scientific article published on November 1966

Allopurinol treatment of malignant uric acid lithiasis in a gouty patient with massive hyperuricosuria

scientific article published on 01 April 1968

Alterations in Purine Metabolism in Cultured Fibroblasts with HGPRT Deficiency and with PRPP Synthetase Superactivity ⬇️

scientific article published on January 1, 1979

Alterations in purine nucleotide metabolism during muscle differentiation in vitro ⬇️

scientific article published on October 31, 1983

Altered kinetic property of erythrocyte phosphoribosylpsyrophosphate synthetase in excessive purine production

scientific article published on 01 August 1972

Atypical patterns of lactate dehydrogenase isoenzymes in acute myocardial infarction

scientific article published on 01 June 1988

Calcium and inorganic phosphate in saliva of patients with primary hyperparathyroidism

scientific article published on 01 January 1974

Calciuric effect of probenecid in gouty patients

scientific article published on 01 April 1983

Cardiomyocytes cultured in serum-free medium. Growth and creatine kinase activity

scientific article published on 01 November 1984

Characterization of Purine Nucleotide Metabolism in Cultured Fibroblasts with Deficiency of Hypoxanthine-Guanine Phosphoribosyltransferase and with Superactivity of Phosphoribosylpyrophosphate Synthetase ⬇️

scientific article published on 01 January 1980

Characterization of purine nucleotide metabolism in primary rat cardiomyocyte cultures

scientific article

Characterization of purine nucleotide metabolism in primary rat muscle cultures ⬇️

scientific article published on June 16, 1982

Characterization of the alterations in purine nucleotide metabolism in hypoxanthine-guanine phosphoribosyltransferase-deficient rat neuroma cell line

scientific article published on August 1993

Characterization of thymocyte subpopulations by enzymatic markers

scientific article published on 01 September 1983

Clinical and biochemical manifestations and molecular characterization of the mutation HPRT Jerusalem

scientific article published in October 2004

Clinical and therapeutic aspects of gout

scientific article published on May 2, 1976

Comment on the assay of purine phosphoribosyltransferases in cultured human fibroblasts

scientific article published on 01 January 1974

Cyclic AMP decreases the availability of 5-phosphortoosyl-1-pyrophosphate and decelerates de novo purine synthesis in rat hepatocytes ⬇️

scientific article published on January 1, 1998

De novo purine synthesis in skeletal muscle

scientific article published on 01 January 1982

De novo synthesis of purine nucleotides and metabolic availability of phosphoribosylpyrophosphate in leukemic leukocytes

scientific article published on February 1, 1979

De novo synthesis of purine nucleotides in human blood platelets

scientific article published on 01 January 1980

De novo synthesis of purine nucleotides in human peripheral blood leukocytes. Excessive activity of the pathway in hypoxanthine-guanine phosphoribosyltransferase deficiency

scientific article published on August 1976

Decelerated rate of dendrite outgrowth from dopaminergic neurons in primary cultures from brains of hypoxanthine phosphoribosyltransferase-deficient knockout mice

scientific journal article

Deficiency of xanthine oxidase activity in colostrum of a xanthinuric female ⬇️

scientific article published on 01 June 1971

Dependence of human erythrocyte PRPP synthetase specific activity on concentration

scientific article published on 01 November 1972

Dependence of the metabolic fate of IMP on the rate of total IMP synthesis. Studies in cultured fibroblasts from normal subjects and from purine-overproducing mutant patients.

scientific article published in May 1980

Developmental changes in purine nucleotide metabolism in cultured rat astroglia

scientific article published in December 1995

Developmental changes in the activity of enzymes of purine metabolism in rat neuronal cells in culture and in whole brain

scientific article

Differences in the activity of adenosine deaminase and of purine nucleoside phosphorylase and in the sensitivity to deoxypurine nucleosides between subpopulations of mouse thymocytes

scientific article published on 01 May 1982

Does determination of serum aspartate aminotransferase contribute to the diagnosis of acute myocardial infarction?

scientific article

Does serial determination of lactate dehydrogenase isoenzymes 1 and 2 ratios contribute to the diagnosis of acute myocardial infarction?

scientific article published on 01 July 1988

Effect of methoxyflurane anesthesia on serum uric acid in man

scientific article published on January 31, 1977

Effects of differentiation-inducing agents on purine nucleotide metabolism in an ovarian cancer cell line.

scientific article published on January 1994

Effects of fructose on purine nucleotide metabolism in isolated rat hepatocytes

scientific article published on 01 January 1984

Effects of fructose on synthesis and degradation of purine nucleotides in isolated rat hepatocytes ⬇️

scientific article published on August 27, 1982

Electrophoretic characterization of human phosphoribosylpyrophosphate synthetase

scientific article published in June 1974

Electrophoretic separation of normal and mutant phosphoribosylpyrophosphate synthetase

scientific article published on 01 January 1974

Elevated serum urate and normocholesterolemia in patients with thromboangiitis obliterans

scientific article published on 01 May 1978

Elevated serum xanthine oxidase activity following biliary tract and gastric surgery

scientific article published on 01 March 1976

Elevation of serum xanthine oxidase activity following halothane anesthesia in man.

scientific article published in October 1977

Elevation of serum xanthine oxidase following halothane anesthesia in the rat ⬇️

scientific article published on May 15, 1976

Enzymatic errors leading to purine overproduction

scientific article published on February 15, 1973

Enzymes of purine metabolism in platelets: phosphoribosylpyrophosphate synthetase and purine phosphoribosyltransferases

scientific article published on 01 January 1973

Enzymes of purine nucleotide metabolism in mature cultures of rat brain neurons

scientific article published on 01 January 1989

Erythrocyte adenine phosphoribosyltransferase in the Lesch-Nyhan syndrome.

scientific article

Erythrocyte glutathione reductase in gout and in glucose-6-phosphate dehydrogenase deficiency

scientific article published on January 1, 1978

Etiologic and therapeutic studies of lithiasis caused by uric acid

scientific article published on 01 January 1966

Evidence for X-linkage of phosphoribosylpyrophosphate synthetase in man. Studies with cultured fibroblasts from a gouty family with mutant feedback-resistant enzyme

scientific article published on January 1977

Evidence for molecular alteration of erythrocyte hypoxanthine-guanine phosphoribosyltransferase in a gouty family with partial deficiency of the enzyme

scientific article published on 01 January 1972

Familial Renal Hypouricaemia: Two Additional Cases with Uric Acid Lithiasis ⬇️

scientific article published on April 1, 1979

Familial gouty malignant uric acid lithiasis due to mutant phosphoribosylpyrophosphate synthetase

scientific article published on 01 July 1973

Familial hypouricemia due to isolated renal tubular abnormality

scientific article published on 01 April 1978

Familial hypouricemia due to isolated renal tubular defect. Attenuated response of uric acid clearance to probenecid and pyrazinamide

scientific article published on 01 January 1977

Familial renal hypouricemia due to isolated tubular defect

scientific article published on January 1, 1977

Frequency and causes of hypouricemia in hospital patients

scientific article published on 01 May 1977

Glycogenolysis-induced acceleration of "de novo" purine synthesis in mouse liver

scientific article published on 01 May 1981

Guanine Metabolism in Primary Rat Neuronal Cells ⬇️

scientific article published on January 1, 1991

Guanine nucleotide metabolism in red blood cells: the metabolic basis for GTP depletion in HGPRT and PNP deficiency

scientific article published on 01 January 1989

Guanine ribonucleotide metabolism in human red blood cells: Evidence for a high rate of GMP dephosphorylation

article

Hereditary hypercalciuric urolithiasis. A study of a family

scientific article published on 01 August 1981

Hereditary renal hypouricemia

scientific article 1977

Hereditary renal hypouricemia with hyperuricosuria and variably absorptive hypercalciuria and urolithiasis--a new syndrome.

scientific article

Hereditary renal hypouricemia: heterogeneity of tubular abnormality

scientific article published on 01 January 1978

High frequency of cystinuria among Jews of Libyan origin

scientific article published on January 1974

Hormone-induced stimulation of phosphoribosylpyrophosphate and of purine synthesis in mouse liver in vivo

scientific article published on 01 January 1986

Human erythrocyte phosphoribosylpyrophosphate synthetase mutationally altered in regulatory properties

scientific article

Hypouricemia, Hypercalciuria, and Decreased Bone Density. A New Hereditary Syndrome ⬇️

scientific article published on 01 January 1974

Hypouricemia, Hypercalciuria, and Decreased Bone Density: A Hereditary Syndrome

scientific article published on 01 April 1974

Hypoxanthine and inosine metabolism in cultured rat cardiomyocytes

scientific article published in January 1991

INCREASED ADENOSINE DEAMINASE ACTIVITY IN PERIPHERAL LYMPHOCYTES IN WALDENSTRÖM'S MACROGLOBULINÆMIA

scientific article published in The Lancet

Implications of Disorders of Purine Metabolism for the Kidney and the Urinary Tract ⬇️

scientific article published on January 1, 1977

Inborn hypouricemia due to isolated renal tubular defect

scientific article published on 01 June 1979

Increased de novo purine synthesis in cultured skin fibroblasts from heterozygotes for the Lesch-Nyhan syndrome. A sensitive marker for carrier detection

scientific article published on 01 January 1979

Increased uric acid clearance in patients with burns

scientific article published on 01 November 1977

Involvement of Src tyrosine kinases (SFKs) and of focal adhesion kinase (FAK) in the injurious mechanism in rat primary neuronal cultures exposed to chemical ischemia

scientific article published on 27 June 2008

Involvement of kidney and urinary tract in pathologic metabolism of purines

scientific article published on June 15, 1977

Ischemic tolerance conferred to cultured rat neurons by heat shock is not mediated by opening of adenosine triphosphate-sensitive potassium channels

scientific article

Juvenile metabolic gout caused by chronic compensated hemolytic syndrome

scientific article published on 01 October 1982

Kelley-Seegmiller syndrome due to a unique variant of hypoxanthine-guanine phosphoribosyltransferase: reduced affinity for 5-phosphoribosyl-1-pyrophosphate manifested only at low, physiological substrate concentrations

scientific article

Kinetic aspects of purine metabolism in cultured fibroblasts. A comparative study of cells from patients overproducing purines due to HGPRT deficiency and PRPP synthetase superactivity

scientific article published on January 1, 1978

Lactate dehydrogenase isoenzymes in serum during recent acute myocardial infarction

scientific article published on 01 August 1987

Lactate dehydrogenase isoenzymes in serum during unstable angina.

scientific article

Lesch-Nyhan syndrome in an Arab family. Detection and biochemical manifestation of heterozygosity

scientific article published on 01 December 1981

Lesch-Nyhan syndrome: biochemical characterization of a case with attenuated behavioral manifestation

scientific article published on 01 January 1984

Low serum creatine phosphokinase values in patients with acute viral hepatitis

scientific article published on 01 April 1984

Metabolic and calcium kinetic studies in idiopathic hypercalciuria

scientific article published on December 1968

Metabolic cooperation between human fibroblasts with normal and with mutant superactive phosphoribosylpyrophosphate synthetase ⬇️

scientific article published on April 29, 1976

Metabolic fate of hypoxanthine and inosine in cultured cardiomyocytes

scientific article published on 01 February 1992

Metabolism of Guanine and Guanine Nucleotides in Primary Rat Cardiomyocyte Cultures

article

Metabolism of Guanine and Guanine Nucleotides in Primary Rat Neuronal Cultures ⬇️

scientific article published on April 1, 1992

Molecular, biochemical, and genetic characterization of a female patient with Lesch-Nyhan disease

scientific article

Mutant feedback-resistant phosphoribosylpyrophosphate synthetase associated with purine overproduction and gout. Phosphoribosylpyrophosphate and purine metabolism in cultured fibroblasts ⬇️

scientific article published on November 1, 1975

Mutant phosphoribosylpyrophosphate synthetase in two gouty siblings with excessive purine production

scientific article published on 01 January 1973

Neuroprotection by NMDA Preconditioning Against Glutamate Cytotoxicity is Mediated Through Activation of ERK 1/2, Inactivation of JNK, and by Prevention of Glutamate-Induced CREB Inactivation ⬇️

scientific article published on May 10, 2011

Normal Activity of Metabolic Pathways Involved in the Formation and Utilization of Phosphoribosylpyrophosphate in Erythrocytes of Patients with Primary Metabolic Gout ⬇️

scientific article published on January 1, 1975

Opening of ATP-sensitive potassium channels by cromakalim confers tolerance against chemical ischemia in rat neuronal cultures ⬇️

scientific article published on July 3, 1998

Opening of K(ATP) channels is mandatory for acquisition of ischemic tolerance by adenosine

scientific article

Orthophosphate treatment of calcium lithiasis associated with idiopathic hypercalciuria

scientific article published on 01 January 1974

Overproduction disease in man due to enzyme feedback resistance mutation. Purine overproduction in gout due to excessive activity of mutant feedback-resistant phosphoribosylpyrophosphate synthetase

scientific article published on January 1, 1978

Oxidative stress activates transcription factor NF-kB-mediated protective signaling in primary rat neuronal cultures

scientific article published in January 2005

Parthyriod hormone and calcitonin in idopathic hypercalciuria

scientific article published on December 10, 1974

Partial deficiency of hypoxanthine-guanine phosphoribosyltransferase associated with gout and uric acid lithiasis

scientific article published on 01 November 1970

Pathways of adenine nucleotide catabolism in primary rat cardiomyocyte cultures

scientific article published on 01 January 1988

Pathways of adenine nucleotide catabolism in primary rat muscle cultures

scientific article

Patterns of lactate dehydrogenase isoenzymes 1 and 2 in serum of patients performing an exercise test

scientific article

Patterns of lactate dehydrogenase isoenzymes in serum of patients with acute pulmonary edema ⬇️

scientific article published on 01 September 1988

Pentose Shunt, Phosphoribosylpyrophosphate Generation and Purine-Phosphoribosyltransferases in Erythrocytes of Patients with Polycythemia vera ⬇️

scientific article published on January 1, 1975

Phospholipase C is involved in the adenosine-activated signal transduction pathway conferring protection against iodoacetic acid-induced injury in primary rat neuronal cultures

scientific article published on 30 October 2004

Phosphoribosylpyrophosphate synthetase and purine phosphoribosyltransferases in human and rabbit blood platelets

scientific article published on 01 January 1972

Practical approach to the diagnosis and treatment of gout

scientific article published on 01 July 1973

Preconditioning of primary rat neuronal cultures against ischemic injury: characterization of the "time window of protection'.

scientific article published in November 1996

Preface

Preface to a supplement to Pharmacy World on the 5TH Symposium of the European Society for the Study of Purine & Pyrimidtne Metabolism in Man (ESSPPMM 1995)

Prenatal diagnosis of Lesch-Nyhan syndrome: experience with three fetuses at risk

scientific article published on 01 September 1989

Proceedings: Characterization of purine metabolism in cultured fibroblasts from a gouty family with feedback-resistant phosphoribosylpyrophosphate synthetase

scientific article published on November 1, 1975

Proceedings: Erythrocytic pathways regulating phosphoribosylpyrophosphate availability in primary metabolic gout and in polycythemia vera

scientific article published on 01 November 1975

Proceedings: Rarity of cystinuria type I among cystinuric Jews of Libyan origin

scientific article published on November 1, 1975

Proceedings: Serum xanthine oxidase in hepatocellular damage

scientific article published on November 1, 1975

Proceedings: Synthesis of purine nucleotides in leukocytes from normal and hypoxanthine-guanine phosphoribosyltransferase-deficient subjects

scientific article published on 01 November 1975

Production and degradation of AMP in cultured rat skeletal and heart muscle: a comparative study

scientific article published on 01 January 1986

Properties of erythrocyte purine phosphoribosyltransferases in partial hypoxanthine-guanine phosphoribosyltransferase deficiency.

scientific article

Protein kinase C-epsilon is involved in the adenosine-activated signal transduction pathway conferring protection against ischemia-reperfusion injury in primary rat neuronal cultures

scientific article

Purine base incorporation into erythrocyte nucleotides and erythrocyte phosphoribosyltransferase activity in primary gout

scientific article published on 01 February 1971

Purine base incorporation into erythrocyte nucleotides in hypoxanthine-guanine phosphoribosyltransferase deficiency ⬇️

scientific article published on 01 April 1971

Purine nucleotide metabolism in cultured neurons and astroglia from HPRT-deficient knockout mice

scientific article published on March 2001

Purine nucleotide metabolism in primary rat skeletal muscle cultures

scientific article published on 01 January 1984

Reactive oxygen species play an important role in iodoacetate-induced neurotoxicity in primary rat neuronal cultures and in differentiated PC12 cells ⬇️

scientific article published on November 20, 2003

Recent data on uric acid lithiasis.

scientific article published on January 1974

Regulation of De Novo Purine Synthesis in Human and Rat Tissue: Role of Oxidative Pentose Phosphate Pathway Activity and of Ribose-5-Phosphate and Phosphoribosylpyrophosphate Availability ⬇️

scientific article published on January 1, 1977

Regulation of de novo purine synthesis in chick liver slices. Role of phosphoribosylpyrophosphate availability and of salvage purine nucleotide synthesis

scientific article published on November 1978

Resistance of erythrocyte adenine phosphoribosyltransferase in the Lesch-Nyhan syndrome to destabilization to heat by hypoxanthine.

scientific article

Serum xanthine oxidase in jaundice ⬇️

scientific article published on August 18, 1975

Significance of increased serum lactate dehydrogenase isoenzyme 5 in acute infero-posterior myocardial infarction

scientific article published on 01 December 1987

Significance of isolated increases in total lactate dehydrogenase and its isoenzymes in serum of patients with bacterial pneumonia

scientific article published on 01 July 1988

Simpler method for the determination of 5-phosphoribosyl-1-pyrophosphate in red blood cells.

scientific article published in June 1972

Some regulatory properties of purine biosynthesis de novo in long-term cultures of epithelial-like rat liver cells ⬇️

scientific article published on February 1, 1978

Stabilization by PRPP of Cellular Purine Phosphoribosyltransferases Against Inactivation by Freezing and Thawing. Study of Normal and Hypoxanthine-Guanine Phosphoribosyltransferase Deficient Human Fibroblasts ⬇️

scientific article published on January 1, 1973

Stimulation of ribose-5-phosphate and 5-phosphoribosyl-1-pyrophosphate generation by pyrroline-5-carboxylate in mouse liver in vivo: Evidence for a regulatory role of ribose-5-phosphate availability in nucleotide synthesis ⬇️

scientific article published on 01 August 1991

Studies on the etiology of uric acid lithiasis. IV. Urinary non-dialyzable substances in idiopathic uric acid lithiasis

scientific article published on 01 September 1965

Superactivity of Phosphoribosylpyrophosphate Synthetase, due to Feedback Resistance, Causing Purine Overproduction and Gout ⬇️

scientific article published on January 1, 1977

Synovial fluid urate concentration in normouricemic and hyperuricemic subjects without joint diseases ⬇️

scientific article published on 01 April 1981

Synthesis and metabolic fate of purine nucleotides in cultured fibroblasts from normal subjects and from purine overproducing mutants ⬇️

scientific article published on December 21, 1978

The Effect of Pyrroline-5-Carboxylate on R5P and PRPP Generation in Mouse Liver in Vivo ⬇️

scientific article published on 01 January 1991

The Metabolism of Adenosine and Distribution of Adenosine Receptor Lymphocytes in two Human Circulating T Cell Subsets ⬇️

scientific article published on January 1, 1981

The activities of enzymes of purine metabolism in murine thymus dependent lymphocytes

scientific article published on 01 January 1984

The adenosine-induced mechanism for the acquisition of ischemic tolerance in primary rat neuronal cultures

scientific article

The diagnostic value of xanthine-oxidase activity in serum of hepatic patients (author's transl)

scientific article published on November 15, 1977

The effect of ribose 5-phosphate and 5-phosphoribosyl-1-pyrophosphate availability on de novo synthesis of purine nucleotides in rat liver slices ⬇️

scientific article published on April 15, 1976

The efficiency of lactate dehydrogenase isoenzyme determination for the diagnosis of acute myocardial infarction

scientific article published on 01 September 1988

The neuroprotective adenosine-activated signal transduction pathway involves activation of phospholipase C.

scientific article published in January 2006

Thyroxine-induced redistribution of creatine kinase isoenzymes in rat cardiomyocyte cultures

scientific article published on 01 June 1989

Total lactate dehydrogenase and its isoenzymes in serum of patients with non-small-cell lung cancer

scientific article published in April 1988

Transfer of resistance to selective conditions from fibroblasts with mutant feedback-resistant phosphoribosylpyrophosphate synthetase to normal cells. A form of metabolic cooperation

scientific article

Transport into erythrocytes and intestinal absorption of uric acid in hereditary renal hypouricemia

scientific article published on June 10, 1975

Urinary xanthine stones in an allopurinol-treated gouty patient with partial deficiency of hypoxanthine-guanine phosphoribosyltransferase

scientific article published on 01 February 1978

Urine xanthine oxidase activity in urinary tract infection

scientific article published on May 1978

Urolithiasis associated with hypercalciuria ⬇️

scientific article published on 01 January 1977

X-Linked Pattern of Inheritance of Gout Due to Mutant Feedback-Resistant Phosphoribosylpyrophosphate Synthetase ⬇️

scientific article published on January 1, 1977

Xanthinuria: An Additional Case with Demonstration of Xanthine Oxidase Deficiency ⬇️

scientific article published on 01 March 1971

[Etiology of uric acid lithiasis. I. Solubility of uric acid and sodium urate in buffer solution]

scientific article published on 01 January 1966

[Hereditary renal hypouricemia with hyperuricosuira, variably associated with hypercalciuria and urolithiasis: a new syndrome]

scientific article published on 01 January 1980

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